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1. 发明授权

US5936098A Process for producing indoline compounds and intermediates for the production of the same 失效
标题翻译：用于生产二氢吲哚化合物的方法和用于生产二氢吲哚化合物的中间体
公开(公告)号：US5936098A
公开(公告)日：1999-08-10
申请号：US894855
申请日：1997-08-14
申请人： Nobuyuki Yasuda , Shin-ichi Kunii , Kouichi Kazama
发明人： Nobuyuki Yasuda , Shin-ichi Kunii , Kouichi Kazama
IPC分类号： C07D209/08 , C07D209/12 , C07D401/06 , C07D403/06
CPC分类号： C07D401/06 , C07D209/08 , C07D209/12 , C07D403/06
摘要： This invention concerns a method for the production of a 3-arylindoline compound represented by the general formula ##STR1##
摘要翻译： PCT No.PCT / JP96 / 00344 Sec。 371日期1997年8月14日 102（e）日期1997年8月14日PCT 1996年2月16日PCT公布。 WO96 / 25396 PCT出版物日期：1996年8月22日本发明涉及一种制备由通式表示的3-芳基二氢吲哚啉化合物的方法

2. 发明授权

US07189717B2 Medicinal compositions promoting bowel movement 失效
标题翻译：促进排便的药物成分
公开(公告)号：US07189717B2
公开(公告)日：2007-03-13
申请号：US10257091
申请日：2001-04-26
申请人： Masahiro Yasuda , Hitoshi Harada , Shuhei Miyazawa , Seiichi Kobayashi , Kokichi Harada , Takayuki Hida , Hisashi Shibata , Nobuyuki Yasuda , Osamu Asano , Yoshihiko Kotake
发明人： Masahiro Yasuda , Hitoshi Harada , Shuhei Miyazawa , Seiichi Kobayashi , Kokichi Harada , Takayuki Hida , Hisashi Shibata , Nobuyuki Yasuda , Osamu Asano , Yoshihiko Kotake
IPC分类号： A61K31/506
CPC分类号： A61K31/506 , A61K31/519 , A61K31/522 , A61K31/5377 , A61K31/7076 , H04B10/112
摘要： The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2 receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.
摘要翻译：本发明提供一种具有温和但强烈的排便促进作用而不引起腹泻的药物。也就是说，它提供了包含具有腺苷A 2受体拮抗作用的化合物，优选腺苷A 2b受体拮抗剂或其盐的排便促进剂。

3. 发明申请

US20050195929A1 Sampling frequency conversion apparatus 审中-公开
标题翻译：采样变频装置
公开(公告)号：US20050195929A1
公开(公告)日：2005-09-08
申请号：US11100128
申请日：2005-04-06
申请人： Nobuyuki Yasuda , Kazunobu Ohkuri
发明人： Nobuyuki Yasuda , Kazunobu Ohkuri
IPC分类号： G10L19/00 , H03H17/00 , H03H17/06 , H04B14/02 , H04B14/04 , H04H5/00 , H04H20/89 , H04L7/02 , H04L25/05 , H04B1/38
CPC分类号： H03H17/0628 , H03H17/0621 , H04B14/026 , H04H20/89 , H04L25/05
摘要： A sampling frequency conversion apparatus which easily controls the phase difference (time difference) between the input data and the output data in converting the sampling frequency, and comprises storage means 13 for continuously writing the input data or the data obtained by over-sampling the input data and for continuously reading out the data written maintaining a predetermined address difference relative to the write address, and interpolation processing means 14 for interpolating the data read out from the storage means 13 to obtain data of which the sampling frequency is converted. In converting the sampling frequency, an address difference between a write address and a read address in the storage means 13 is optimized, the address difference being optimized without limitation for a predetermined period of time from the start of supplying the input data and, then, being optimized by imposing a predetermined limitation after the passage of the predetermined period of time.
摘要翻译：一种采样频率转换装置，其在转换采样频率时容易地控制输入数据和输出数据之间的相位差（时间差），并且包括用于连续写入输入数据或通过对输入进行过采样而获得的数据的存储装置13 数据，并连续地读出相对于写入地址保持预定地址差的写入数据;以及内插处理装置14，用于内插从存储装置13读出的数据，以获得采样频率被转换的数据。在转换采样频率时，优化存储装置13中的写入地址和读取地址之间的地址差异，在从提供输入数据开始的预定时间段内对地址差进行优化，而不限于此，通过在经过预定时间段之后施加预定的限制来优化。

4. 发明授权

US06841549B1 Condensed imidazole compounds and a therapeutic agent for diabetes mellitus 失效
标题翻译：缩合咪唑化合物和糖尿病治疗剂
公开(公告)号：US06841549B1
公开(公告)日：2005-01-11
申请号：US10018688
申请日：2000-06-30
申请人： Osamu Asano , Hitoshi Harada , Seiji Yoshikawa , Nobuhisa Watanabe , Takashi Inoue , Tatsuo Horizoe , Nobuyuki Yasuda , Kaya Ohashi , Hiroe Minami , Junsaku Nagaoka , Manabu Murakami , Seiichi Kobayashi , Isao Tanaka , Tsutomu Kawata , Naoyuki Shimomura , Hiroshi Akamatsu , Naoki Ozeki , Toshikazu Shimizu , Kenji Hayashi , Toyokazu Haga , Shigeto Negi , Toshihiko Naito
发明人： Osamu Asano , Hitoshi Harada , Seiji Yoshikawa , Nobuhisa Watanabe , Takashi Inoue , Tatsuo Horizoe , Nobuyuki Yasuda , Kaya Ohashi , Hiroe Minami , Junsaku Nagaoka , Manabu Murakami , Seiichi Kobayashi , Isao Tanaka , Tsutomu Kawata , Naoyuki Shimomura , Hiroshi Akamatsu , Naoki Ozeki , Toshikazu Shimizu , Kenji Hayashi , Toyokazu Haga , Shigeto Negi , Toshihiko Naito
IPC分类号： A61P3/10 , A61P43/00 , C07D471/04 , C07D473/00 , C07D473/34 , C07D473/40 , A16K31/33 , C07D239/70 , C07D471/00 , C07D487/00 , A16K31/52
CPC分类号： C07D471/04 , C07D473/00 , C07D473/34 , C07D473/40
摘要： The present invention provides a preventive or therapeutic agent for diabetes mellitus and diabetic complications, which is a new type based on an adenosine A2 receptor antagonist action.That is, it provides a novel condensed imidazole compound which has an adenosine A2 receptor antagonist action, is effective for preventing or treating diabetes mellitus and diabetic complications, and is represented by the formula (I); (wherein R1 represents e.g. an amino group which may be substituted with an alkyl group; R2 represents e.g. hydrogen atom, an alkyl group, a cycloalkyl group or an alkyl group, alkenyl group or alkynyl group which may be substituted with hydrox etc.; R3 represents e.g. an optionally substituted alkyl group, alkenyl group, alkynyl group, aryl group, heteroaryl group, pyridinone group, pyrimidinone group or piperadinone group; Ar represents e.g. an optionally substituted aryl or heteroaryl group; and Q and W are the same as or different from each other and each represents N or CH), a pharmacologically acceptable salt or hydrates thereof.
摘要翻译：本发明提供了一种基于腺苷A2受体拮抗剂作用的新型糖尿病和糖尿病并发症的预防或治疗剂。即提供了具有腺苷A2受体拮抗剂作用的新颖的缩合咪唑化合物，是有效预防或治疗糖尿病和糖尿病并发症，并由式（I）表示;（其中R 1表示例如可被烷基取代的氨基; R 2表示例如氢原子，可以被羟基取代的烷基，环烷基或烷基，烯基或炔基; R 3表示例如任选取代的烷基，烯基，炔基，芳基，杂芳基，吡啶酮基，嘧啶酮基或哌嗪酮基; Ar表示例如任选取代的芳基或杂芳基; Q和W彼此相同或不同，每个代表 N或CH），其药理学上可接受的盐或其水合物。

5. 发明授权

US06750232B2 2-aminopyridine compounds and use thereof as drugs 失效
标题翻译： 2-氨基吡啶化合物及其作为药物的用途
公开(公告)号：US06750232B2
公开(公告)日：2004-06-15
申请号：US10333689
申请日：2003-01-23
申请人： Hitoshi Harada , Osamu Asano , Shuhei Miyazawa , Masato Ueda , Masahiro Yasuda , Nobuyuki Yasuda
发明人： Hitoshi Harada , Osamu Asano , Shuhei Miyazawa , Masato Ueda , Masahiro Yasuda , Nobuyuki Yasuda
IPC分类号： C07D40102
CPC分类号： C07D213/80 , A61K31/4409 , A61K31/443 , A61K31/4436 , A61K31/444 , A61K31/455 , C07D213/82 , C07D213/85 , C07D405/04 , C07D405/14 , C07D409/14
摘要： A class of substituted compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by formula (II), wherein R1 is selected from hydrido, halo, alkoxy, aryl, alkylthio, alkylamino, aralkoxy, azido and alkenyloxy; wherein R2 is selected from hydrido, cyano, hydroxyalkyl, haloalkyl, aminoalkyl, alkylaminoalkyl, alkylcarbonyloxyalkyl, aminocarbonyl and alkylcarbonylaminoalkyl; and wherein R5 and R6 are one more radicals independently selected from halo, alkylsulfonyl, aminosulfonyl, alkoxy and alkylthio; provided one of R5 and R6 is substituted with alkysulfonyl, aminosulfonyl, or haloalkylsulfonyl; or a pharmaceutically-acceptable salt thereof.
摘要翻译：描述了一类取代的化合物用于治疗炎症和炎症相关疾病。特别感兴趣的化合物由式（II）定义，其中R 1选自氢，卤素，烷氧基，芳基，烷硫基，烷基氨基，芳烷氧基，叠氮基和烯氧基; 氰基，羟基烷基，卤代烷基，氨基烷基，烷基氨基烷基，烷基羰氧基烷基，氨基羰基和烷基羰基氨基烷基;其中R 2选自氢，氰基，并且其中R 5和R 6分别独立地选自卤素，烷基磺酰基，氨基磺酰基，烷氧基和烷硫基; 其中R 5和R 6之一被烷基磺酰基，氨基磺酰基或卤代烷基磺酰基取代; 或其药学上可接受的盐。

6. 发明授权

US06701055B2 Apparatus and method for cutting plastic optical fiber 失效
标题翻译：塑料光纤切割装置及方法
公开(公告)号：US06701055B2
公开(公告)日：2004-03-02
申请号：US10151414
申请日：2002-05-20
申请人： Nobuyuki Yasuda
发明人： Nobuyuki Yasuda
IPC分类号： G02B600
CPC分类号： B26D11/00 , B26D1/04 , B26D3/16 , B26D7/086 , B26D7/10 , G02B6/02033 , G02B6/25 , Y10T83/0405 , Y10T83/145 , Y10T83/202 , Y10T83/283
摘要： The present invention provides a method and an apparatus for cutting a plastic optical fiber having a cladding layer. The method includes a plurality of cutting steps for performing rough cutting under a rough cutting condition and finish cutting under a controlled cutting condition. With this method, since a load applied to an optical fiber upon cutting is reduced, degradation of transmission characteristics of the optical fiber after cutting can be reduced.
摘要翻译：本发明提供一种用于切割具有包覆层的塑料光纤的方法和设备。该方法包括多个切割步骤，用于在粗切割条件下进行粗切割，并在受控的切割条件下进行切割。利用这种方法，由于减少了在切割时施加到光纤上的负载，所以可以降低切割后的光纤的传输特性的劣化。

7. 发明授权

US06692287B2 Connector 失效
标题翻译：连接器
公开(公告)号：US06692287B2
公开(公告)日：2004-02-17
申请号：US10169629
申请日：2002-10-15
申请人： Nobuyuki Yasuda
发明人： Nobuyuki Yasuda
IPC分类号： H01R13/627 , H01R24/14
CPC分类号： H01R13/6275
摘要： A connection device including a plug unit (P) which has a connector plug (3) provided at an end portion of a signal cable and a receptacle unit (R) in which the plug unit (P) is inserted. The plug unit (P) has an unlocking member (4) supported on an outer circumferential surface of the connector plug (3) so as to be movable in the axial direction of the cable (2) and has a knob portion (12) mounted thereon. The receptacle unit (R), in which the plug unit (P) can be inserted and removed, has a lock member (5) housed in the receptacle unit (R) and adapted for being engaged with the connector plug (3) to lock the plug unit (P) and controlled by movement of the unlocking member (4) in the axial direction of the cable (2) via a cam portion (40) (41) provided on an outer circumferential surface of the unlocking member (4), thus locking and unlocking the connector plug (3) inserted in the receptacle unit (R).
摘要翻译：一种连接装置，包括具有设置在信号电缆的端部的连接器插头（3）的插头单元（P）和插入插头单元（P）的插座单元（R）。插头单元（P）具有支撑在连接器插头（3）的外周面上的解锁构件（4），以便能够在电缆（2）的轴向方向上移动，并且具有安装在该电缆上。可插拔插头单元（P）的插座单元（R）具有容纳在插座单元（R）中并适于与连接器插头（3）接合以锁定的锁定构件（5）所述插头单元（P）通过设置在所述解锁构件（4）的外周面上的凸轮部（40）（41）在所述电缆（2）的轴向上由所述解锁构件（4）的移动而被控制，从而锁定和解锁插入插座单元（R）中的连接器插头（3）。

8. 发明授权

US06637105B1 Method of manufacturing a multilayer printed wiring board 失效
标题翻译：制造多层印刷线路板的方法
公开(公告)号：US06637105B1
公开(公告)日：2003-10-28
申请号：US09637859
申请日：2000-08-15
申请人： Yoshio Watanabe , Nobuyuki Yasuda , Hironori Mihono , Yuji Nishitani
发明人： Yoshio Watanabe , Nobuyuki Yasuda , Hironori Mihono , Yuji Nishitani
IPC分类号： H01K310
CPC分类号： H05K3/4614 , H05K3/321 , H05K3/4046 , H05K3/4069 , H05K3/4623 , H05K2201/0367 , H05K2201/0394 , H05K2201/09536 , H05K2201/0959 , H05K2201/09827 , H05K2201/10378 , H05K2203/063 , H05K2203/0733 , H05K2203/1157 , Y10T29/49128 , Y10T29/49155 , Y10T29/49165
摘要： The invention provides a high-density multilayer printed wiring board and a method for manufacturing a multilayer printed wiring board having high-density wiring that is formed easily. A method for manufacturing a multilayer printed wiring board formed by laminating a plurality of laminates comprises a step for forming a conduction hole on a laminate comprising an insulating board having both sides on which conductive films are formed, a step for electrically connecting between both sides of said laminate through the above-mentioned conduction hole and planarizing the surface, a step for patterning the above-mentioned conductive film desiredly and forming a projection member at a desired position of the above-mentioned conductive film, a step for laminating bonding members having a through hole to which the above-mentioned projection member is inserted, which is served for bonding between the above-mentioned laminates, and the above-mentioned laminates alternately with insertion of the above-mentioned projection member into the above-mentioned throughhole, and a step for press-molding the above-mentioned laminated laminates and bonding members with heating.
摘要翻译：本发明提供了一种高密度多层印刷线路板和一种容易形成高密度布线的多层印刷布线板的制造方法。制造通过层叠多个层叠体而形成的多层印刷布线板的方法包括在层叠体上形成导电孔的步骤，该叠层包括具有两侧的绝缘板，形成有导电膜的步骤，所述层压体通过上述导电孔并使表面平坦化，所需的上述导电膜图案化步骤和在上述导电膜的所需位置形成突起构件的步骤，用于层压具有上述凸起构件插入到上述通孔中的用于上述层叠体之间的粘合的上述凸起构件和上述层压体的通孔交替地插入上述通孔中，并且用于加热上述层叠层叠体和粘接部件的压制成形工序。

9. 发明授权

US5311559A Apparatus for correcting waveform distortion 失效
标题翻译：用于校正波形失真的装置
公开(公告)号：US5311559A
公开(公告)日：1994-05-10
申请号：US940102
申请日：1992-09-03
申请人： Nobuyuki Yasuda
发明人： Nobuyuki Yasuda
IPC分类号： H03K5/131 , H03K5/14 , H04L25/03 , H04L25/49 , H04L7/06
CPC分类号： H04L25/4904
摘要： An apparatus for correcting wave distortion. An input signal is supplied to a delay circuit, the input signal being so modulated that an accumulated value of a time interval from its leading edge to its trailing edge equals another accumulated value of another time interval from a trailing edge to a leading edge. The delay circuit generates plural successively delayed outputs, each of which has a certain time delay shorter than the time interval. A selector selects a plurality of delayed signals among the plural delayed outputs. A synthesizer synthesizes a plurality of delayed signals so that a synthesized signal can be obtained by correcting at least one of the time interval and the another time interval through the certain time delay. A detector detects a difference between a time interval from a leading edge to a trailing edge and another time interval from a trailing edge to a leading edge of the synthesized signal out of the synthesizer. A generator generates a control signal which controls, based on a detected output by the detector, the selecting operation and the synthesizing operation so as to accumulate a value of a time interval from a leading edge to a trailing edge of the synthesized signal equal to another accumulated value of another time interval from a trailing edge to a leading edge of the synthesized signal.
摘要翻译：用于校正波形失真的装置。输入信号被提供给延迟电路，输入信号被调制成使得从其前沿到其后沿的时间间隔的累积值等于从后沿到前沿的另一个时间间隔的另一累积值。延迟电路产生多个相继延迟的输出，每个输出的时间延迟比时间间隔短。选择器选择多个延迟输出中的多个延迟信号。合成器合成多个延迟信号，从而可以通过在一定的时间延迟中校正时间间隔和另一时间间隔中的至少一个来获得合成信号。检测器检测从前沿到后沿的时间间隔和从合成器的合成信号的后沿到前沿的另一时间间隔之间的差异。发生器产生控制信号，该控制信号基于检测器的检测输出来控制选择操作和合成操作，以便累加从合成信号的前沿到后沿等于另一个的时间间隔的值从合成信号的后沿到前沿的另一个时间间隔的累积值。

10. 发明授权

US4744649A Ophthalmological measuring apparatus 失效
标题翻译：眼科测量仪器
公开(公告)号：US4744649A
公开(公告)日：1988-05-17
申请号：US863046
申请日：1986-05-14
申请人： Masao Niino , Nobuyuki Yasuda , Koichiro Kakizawa , Tadashi Ichihashi , Masunori Kawamura
发明人： Masao Niino , Nobuyuki Yasuda , Koichiro Kakizawa , Tadashi Ichihashi , Masunori Kawamura
IPC分类号： A61B3/117 , A61B3/12 , A61B3/135 , A61B3/10 , A61B3/14
CPC分类号： A61B3/135 , A61B3/10
摘要： An ophthalmological measuring apparatus having a laser-slit projector unit for projecting a laser beam on a portion in a human eyeball, a microscope unit adapted for receiving and observing the light reflected from the portion in the eyeball and a detector unit adapted for displaying the observing point in the eyeball projected by the laser beam. The microscope unit includes an objective optical system, an imaging optical system, a scattered light pickup prism disposed between the objective optical system and the imaging optical system and having a reflecting surface for diverging and directing a part of the reflected light, a beam splitter for superposing another optical axis parallel to the optical axis diverged by the prism on the optical axis of the imaging optical system, a converging optical system for receiving the diverged optical axis and the other optical axis parallel thereto, and an optical fiber having one end disposed adjacent to the focal plane of the converging optical system and movable up and down and right and left. The detector unit includes a photoelectric device directed to the other end of the optical fiber, a wavelength separating mirror disposed between the other end of the optical fiber and the photoelectric device, a light emitting diode disposed on the reflecting side of the mirror and adapted for emitting light having a wavelength different from that of the laser beam, and a right-to-left inverting optical system disposed between the beam splitter and the converging optical system.
摘要翻译：一种眼科测量装置，具有用于将激光束投射在人眼球部分上的激光狭缝投影仪单元，适于接收和观察从眼球部分反射的光的显微镜单元和适于显示观察的检测器单元指向由激光束投影的眼球。显微镜单元包括物镜光学系统，成像光学系统，设置在物镜光学系统和成像光学系统之间的散射光拾取棱镜，并具有用于发散和引导部分反射光的反射表面，用于将与棱镜分离的光轴平行的另一个光轴叠加在成像光学系统的光轴上，会聚光学系统用于接收发散的光轴和与其平行的另一个光轴，以及光纤，其一端设置在相邻到会聚光学系统的焦平面，上下左右移动。检测器单元包括指向光纤另一端的光电装置，设置在光纤的另一端和光电装置之间的波长分离镜，设置在反射镜的反射面上的发光二极管，发射具有与激光束不同的波长的光，以及设置在分束器和会聚光学系统之间的从右到左的反转光学系统。

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