会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 10. 发明申请
    • POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF
    • 含有降解可控离子基团的聚(有机磷),其制备方法及其用途
    • US20140031289A1
    • 2014-01-30
    • US13569737
    • 2012-08-08
    • Soo-Chang SONGYoung-Min Kim
    • Soo-Chang SONGYoung-Min Kim
    • C08G79/02A61K47/34
    • C08G79/025A61K47/34
    • The present invention relates to a thermosensitive phosphazene-based polymer having a degradation controllable ionic group, a use thereof, and a use thereof as a material for delivering bioactive substances. The phosphazene-based polymer according to the present invention has the thermosensitivity of showing the temperature-dependent sol-gel phase transition. Thus, it forms a gel phase at the body temperature when it is injected into the body to make it easy to control the release of bioactive substances such as drugs, and has the functional groups capable of making chemical bonds such as ionic bond, covalent bond, coordinate bond, etc. with drugs and thus is excellent in bearing the drugs. Since it can control the degradation rate depending on the kind of ionic group, it can selectively control the release time depending on the characteristics of drugs. Furthermore, it has an excellent biocompatibility and thus is very useful as a material for delivery of bioactive substances such as drugs, etc.
    • 本发明涉及具有降解可控离子基团的热敏磷腈基聚合物,其用途及其用作输送生物活性物质的材料的用途。 根据本发明的磷腈基聚合物具有显示温度依赖性溶胶 - 凝胶相变的热敏性。 因此,当其注入体内时,其在体温下形成凝胶相,以便容易地控制生物活性物质如药物的释放,并且具有能够进行化学键的官能团,例如离子键,共价键 ,配合药物等,因此具有优异的耐药性。 由于可以根据离子基团的种类控制降解速率,因此可根据药物的特性选择性地控制释放时间。 此外,它具有优异的生物相容性,因此作为用于递送生物活性物质如药物等的材料是非常有用的。