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1. 发明授权

US06395717B1 Therapeutic drug for endotoxin blood symptom and multi-organ failure induced thereby 失效
标题翻译：由此引起内毒素血症和多器官功能衰竭的治疗药物
公开(公告)号：US06395717B1
公开(公告)日：2002-05-28
申请号：US08776032
申请日：1997-01-23
申请人： Michio Ohta , Takaaki Hasegawa , Masayuki Nadai , Yasuko Yoshida , Mitsuo Kawase , Tadahiko Inukai
发明人： Michio Ohta , Takaaki Hasegawa , Masayuki Nadai , Yasuko Yoshida , Mitsuo Kawase , Tadahiko Inukai
IPC分类号： A61K31726
CPC分类号： A61K31/726 , A61K31/7012 , A61K31/715 , Y10S514/921
摘要： Therapeutic drugs for endotoxin blood symptom and multi-organ failure induced by it is provided, which therapeutic during are composed of sialic acid its salt, polymers of sialic acid or a salt of the polymer as effective components and have high therapeutic effects for shock death and organ failure induced by endotoxin as well as high safety, and are effective for treatment of endotoxin-shock, and organ failure.
摘要翻译：提供了由其引起的内毒素血症和多器官功能衰竭的治疗药物，其由唾液酸盐，唾液酸聚合物或聚合物的盐作为有效成分组成，对休克死亡具有很高的治疗效果，内毒素引起的器官功能衰竭以及安全性高，对内毒素休克和器官功能衰竭有效。

2. 发明授权

US5610139A Antimicrobial compositions and pharmaceutical preparations thereof 失效
标题翻译：抗微生物组合物及其药物制剂
公开(公告)号：US5610139A
公开(公告)日：1997-03-11
申请号：US375165
申请日：1995-01-18
申请人： Michio Ohta , Nobuo Kato
发明人： Michio Ohta , Nobuo Kato
IPC分类号： A61K31/545 , A61K31/16 , A61K31/43 , A61K38/00 , A61K38/17 , A61P31/04 , A61K38/10
CPC分类号： A61K38/1767
摘要： Antimicrobial compositions which are effective against methicillin-resistant Staphylococcus aureus organisms (MRSAs) contain peptides isolated from horseshoe crabs combined with one or more .beta.-lactam antibiotics and/or chloramphenicol antibiotics. The compositions exhibit synergistic bactericidal effects against MRSAs at low concentrations, and can be used as defensive agents against opportunistic infections.
摘要翻译：对耐甲氧西林金黄色葡萄球菌生物（MRSA）有效的抗微生物组合物含有从一种或多种β-内酰胺抗生素和/或氯霉素抗生素组合的马蹄蟹分离的肽。该组合物在低浓度下表现出对MRSA的协同杀菌作用，并且可以用作针对机会性感染的防御剂。

3. 发明授权

US4538481A First-order balancer of internal combustion engine 失效
标题翻译：一级内燃机平衡机
公开(公告)号：US4538481A
公开(公告)日：1985-09-03
申请号：US632265
申请日：1984-07-19
申请人： Michio Ohta , Sakito Kamei , Kazumi Aoki
发明人： Michio Ohta , Sakito Kamei , Kazumi Aoki
IPC分类号： F02B3/06 , F02B75/18 , F16C3/20 , F16F15/26 , F16C3/06
CPC分类号： F16C3/20 , F16F15/264 , F02B2075/1816 , F02B3/06 , Y10T74/2183
摘要： The present application discloses a first-order balancer of an internal combustion engine comprising forward-rotating fly-wheels fitted on both ends of a shaft and allowed to rotate in the same direction as said shaft, backward-rotating fly-wheels fitted respectively on said both forward-rotating fly-wheels and allowed to rotate in the opposite direction from said both forward-rotating fly-wheels, forward-rotational counterweights placed on said both forward-rotating fly-wheels, and backward-rotational counterweights placed on said both backward-rotating fly-wheels and having a different weight from said both forward-rotational counterweights. According to the first-order balancer of an internal combustion engine of the present invention, vertical and horizontal first-order unbalanced moments arising in an internal combustion engine may be simultaneously balanced.
摘要翻译：本申请公开了一种内燃机的一级平衡器，其包括安装在轴的两端并允许沿与所述轴相同的方向旋转的正向旋转的飞轮，分别安装在所述轴上的向后旋转的飞轮两个向前旋转的飞轮并且允许沿着与所述两个向前旋转的飞轮相反的方向旋转，放置在所述两个向前旋转的飞轮上的前向旋转配重以及放置在所述两个向前旋转的飞轮上的向后旋转的配重并且具有与所述两个正向旋转配重不同的重量。根据本发明的内燃机的一阶平衡器，可以同时平衡在内燃机中产生的垂直和水平一级不平衡力矩。

4. 发明授权

US07264959B2 Synthase of cereulide produced by Bacillus cereus, gene encoding the same and method of detecting cereulide 失效
标题翻译：蜡状芽孢杆菌产生的大脑合成酶，编码基因的基因和检测大肠杆菌的方法
公开(公告)号：US07264959B2
公开(公告)日：2007-09-04
申请号：US10513786
申请日：2003-05-16
申请人： Michio Ohta , Norio Agata
发明人： Michio Ohta , Norio Agata
IPC分类号： C12N1/20 , C12N9/00 , C12N15/70 , C12Q1/68 , C07H21/04
CPC分类号： C12N9/00 , C07K14/32 , C07K16/40
摘要： It is intended to provide a method of conveniently and quickly detecting cereulide which is an emetic toxin produced by Bacillus cereus. Cereulide is detected using the presence of cereulide synthase in a specimen as an indication. The presence of cereulide synthase is examined by detecting a nucleic acid encoding this enzyme or by an immunological method with the use of an antibody specific to the enzyme.
摘要翻译：旨在提供一种方便快捷地检测作为蜡状芽孢杆菌产生的催吐毒素的大肠杆菌的方法。使用样品中存在大量的合成酶作为指标来检测Cereulide。通过检测编码该酶的核酸或通过使用对该酶特异的抗体的免疫学方法来检查cereulide合酶的存在。

5. 发明授权

US5722818A Suction valve arrangement for a hermetic compressor 失效
标题翻译：一种封闭式压缩机的抽吸阀装置
公开(公告)号：US5722818A
公开(公告)日：1998-03-03
申请号：US707178
申请日：1996-09-03
申请人： Michio Ohta , Hirokazu Kawakami , Shuji Kawashima
发明人： Michio Ohta , Hirokazu Kawakami , Shuji Kawashima
IPC分类号： F04B39/10 , F04B53/10 , F04B37/00
CPC分类号： F04B39/1073
摘要： A hermetically sealed type compressor having a valve seat plate equipped with a plurality of suction holes to effectively suck a refrigerant into a cylinder and capable of preventing the breakage of the valve seat plate coming from the opening and closing operations of a suction reed valve. A partition 50 between adjacent suction holes in the valve seat plate 15 is made to have a constant dimension, thus maintaining a given strength of the partition section and preventing the breakage of the partition 50 coming from the opening and closing movements of the suction reed valve. In addition, in the valve seat plate 15, a cavity 22 or a groove 37 is formed to define a low-pressure space 36 communicating with the plurality of suction holes 24, 25, thereby reducing the suction resistance.
摘要翻译：一种气密密封型压缩机，其具有装配有多个吸入孔的阀座板，以有效地将制冷剂吸入气缸中并且能够防止来自吸入簧片阀的打开和关闭操作的阀座板的破损。阀座板15中相邻的吸入孔之间的隔板50具有恒定的尺寸，从而保持分隔部分的给定强度，并且防止隔板50从吸入簧片阀的打开和关闭运动中断。此外，在阀座板15中，形成有空腔22或槽37，以限定与多个吸入孔24,25连通的低压空间36，从而降低吸入阻力。

6. 发明授权

US5338378A Dental gold alloy with age-hardenability at intraoral temperature 失效
标题翻译：在口腔内温度下具有年龄硬化性的牙科金合金
公开(公告)号：US5338378A
公开(公告)日：1994-08-16
申请号：US51299
申请日：1993-04-23
申请人： Michio Ohta , Shigeki Matsuya , Takanobu Shiraishi , Masaharu Nakagawa
发明人： Michio Ohta , Shigeki Matsuya , Takanobu Shiraishi , Masaharu Nakagawa
IPC分类号： A61K6/04 , A61L27/00 , C22C5/02 , C22F1/00 , C22F1/14
CPC分类号： A61K6/046 , C22C5/02
摘要： A dental gold alloy which is soft enough for adjustment of a patient's occlusal condition, which is age-hardenable with passage of time at temperatures encountered within a patient's oral cavity, and which has a single phase structure which imparts improved corrosion resistance, the dental gold alloy consisting essentially of 82-67% by a weight of gold; 18-33% by weight of copper; and 2-8 at % of an age-hardening accelerator which is at least one metal selected from the group consisting of gallium, aluminum and zinc, wherein the dental gold alloy has been subjected to a solution treatment by heating at 670-700.degree. C. and quenching into water.
摘要翻译：一种牙科金合金，其足够柔软以调节患者的咬合状况，其随着时间的流逝在患者口腔内遇到的温度下老化，并且具有赋予改善的耐腐蚀性的单相结构，牙科金合金基本上由金重量的82-67％组成; 18-33重量％的铜; 和至少一种选自镓，铝和锌的金属的时效硬化促进剂的2-8at％，其中所述牙科金合金已经在670-700℃加热进行固溶处理并淬火入水中。

7. 发明授权

US4147161A Intracranial pressure monitoring method and system 失效
标题翻译：颅内压监测方法及系统
公开(公告)号：US4147161A
公开(公告)日：1979-04-03
申请号：US827740
申请日：1977-08-25
申请人： Jun Ikebe , Yoriaki Kumagai , Kintomo Takakura , Michio Ohta
发明人： Jun Ikebe , Yoriaki Kumagai , Kintomo Takakura , Michio Ohta
IPC分类号： A61B5/00 , A61B5/03 , G01L7/00
CPC分类号： A61B5/031
摘要： System for measuring or monitoring the intracranial pressure which comprises a non-elastic detecting pouch to be inserted into the space between the skull and the cerebrum, a flexible tube connected to the pouch, a device for supplying a liquid into the pouch through the flexible tube and a device for measuring the pressure of the liquid in the pouch. When the pressure of the liquid reaches the intracranial pressure, the curve showing relation between liquid pressure vs. pouch volume flattens. Thus, by measuring the pressure of the flattened region, intracranial pressure may be determined.
摘要翻译：用于测量或监测颅内压的系统，其包括插入颅骨和大脑之间的空间中的非弹性检测袋，连接到小袋的柔性管，用于通过柔性管将液体供应到袋中的装置以及用于测量袋中的液体的压力的装置。当液体的压力达到颅内压时，曲线表示液体压力与袋体积平坦度之间的关系。因此，通过测量平坦化区域的压力，可以确定颅内压。

8. 发明申请

US20060194748A1 Methods for treating disorders induced by H. pylori infections and pharmaceutical compositions for the same 审中-公开
标题翻译：用于治疗由幽门螺杆菌感染诱导的病症的方法及用于其的药物组合物
公开(公告)号：US20060194748A1
公开(公告)日：2006-08-31
申请号：US11066476
申请日：2005-02-28
申请人： Masaaki Minami , Takafumi Ando , Hidemi Goto , Michio Ohta
发明人： Masaaki Minami , Takafumi Ando , Hidemi Goto , Michio Ohta
IPC分类号： A61K31/7048 , A61K31/43 , A61K31/198
CPC分类号： A61K45/06 , A61K31/198 , A61K31/43 , A61K31/7048 , A61K2300/00
摘要： The present invention provides a pharmaceutical composition for the treatment of disorders induced, caused, and/or mediated by Helicobacter pylori infection, as well as methods of treating the same by administering the pharmaceutical composition of the present invention.
摘要翻译：本发明提供了用于治疗由幽门螺杆菌感染诱导，引起和/或介导的病症的药物组合物，以及通过施用本发明的药物组合物来治疗疾病的方法。

9. 发明申请

US20050260589A1 Synthase of cereulide produced by bacillus cereus, gene encoding the same and method of detecting cereulide 失效
标题翻译：由蜡状芽孢杆菌产生的大肠杆菌合成酶，编码基因的基因和检测大肠杆菌的方法
公开(公告)号：US20050260589A1
公开(公告)日：2005-11-24
申请号：US10513786
申请日：2003-05-16
申请人： Michio Ohta , Norio Agata
发明人： Michio Ohta , Norio Agata
IPC分类号： C07K14/32 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N9/00 , C12Q1/68 , C07H21/04 , C12N9/64 , C12P21/06
CPC分类号： C12N9/00 , C07K14/32 , C07K16/40
摘要： It is intended to provide a method of conveniently and quickly detecting cereulide which is an emetic toxin produced by Bacillus cereus. Cereulide is detected using the presence of cereulide synthase in a specimen as an indication. The presence of cereulide synthase is examined by detecting a nucleic acid encoding this enzyme or by an immunological method with the use of an antibody specific to the enzyme.
摘要翻译：旨在提供一种方便快捷地检测作为蜡状芽孢杆菌产生的催吐毒素的大肠杆菌的方法。使用样品中存在大量的合成酶作为指标来检测Cereulide。通过检测编码该酶的核酸或通过使用对酶特异的抗体的免疫学方法来检查cereulide合酶的存在。

10. 发明授权

US5031871A Outside mirror assembly for motor vehicles 失效
标题翻译：机动车外镜组件
公开(公告)号：US5031871A
公开(公告)日：1991-07-16
申请号：US446551
申请日：1989-12-06
申请人： Michio Ohta , Hideharu Naganuma
发明人： Michio Ohta , Hideharu Naganuma
IPC分类号： B60R1/06
CPC分类号： B60R1/06
摘要： In an outside mirror assembly for motor vehicles, having a mirror installed pivotably inside an enclosure fixed to a stay, the retaining force of a structure pivotably holding the mirror can be adjusted and the mirror can be detached and reinstalled. The holding structure can be removably installed by means of a fixture inside the enclosure fixed to the stay. A back plate holding the mirror is pivotably supported to the holding structure, and the force of the holding structure for retaining the back plate can be adjusted. The enclosure has formed therein an opening through which a tool for adjusting the retaining force of the holding structure and for removing or reinstalling the fixture can be introduced, and a cover is removably attached to the enclosure to close said opening.
摘要翻译：在用于机动车辆的外部反射镜组件中，具有可旋转地安装在固定到支柱的外壳内的镜子，可以调节可枢转地保持反射镜的结构的保持力，并且可以拆卸并重新安装镜子。保持结构可以通过固定在支架的外壳内的夹具可拆卸地安装。保持镜子的背板可枢转地支撑在保持结构上，并且可以调节保持背板的保持结构的力。外壳在其中形成有开口，通过该开口可以引入用于调节保持结构的保持力并用于移除或重新安装固定装置的工具，并且盖可移除地附接到外壳以封闭所述开口。

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