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1. 发明申请

US20070103693A1 Method of bioimage data processing for revealing more meaningful anatomic features of diseased tissues 有权
标题翻译：生物图像数据处理方法，用于揭示病变组织的更有意义的解剖特征
公开(公告)号：US20070103693A1
公开(公告)日：2007-05-10
申请号：US11223549
申请日：2005-09-09
申请人： Matthew Everett , Scott Meyer , Paul Stetson , Yan Zhou
发明人： Matthew Everett , Scott Meyer , Paul Stetson , Yan Zhou
IPC分类号： G01B9/02 , G06K9/00 , A61B5/05 , A61B5/103
CPC分类号： A61B5/0066 , G06T7/0014 , G06T19/00 , G06T2200/24 , G06T2207/10101 , G06T2207/30041 , G06T2210/41
摘要： The present invention discloses a method for generating elevation maps or images of a tissue layer/boundary with respect to a fitted reference surface, comprising the steps of finding and segmenting a desired tissue layer/boundary; fitting a smooth reference surface to the segmented tissue layer/boundary; calculating elevations of the same or other tissue layer/boundary relative to the fitted reference surface; and generating maps of elevation relative to the fitted surface. The elevation can be displayed in various ways including three-dimensional surface renderings, topographical contour maps, contour maps, en-face color maps, and en-face grayscale maps. The elevation can also be combined and simultaneously displayed with another tissue layer/boundary dependent set of image data to provide additional information for diagnostics.
摘要翻译：本发明公开了一种用于产生相对于拟合的参考表面的组织层/边界的仰角图或图像的方法，包括以下步骤：找到并分割所需的组织层/边界; 将平滑的参考表面拟合到分段的组织层/边界; 计算相对于拟合参考表面的相同或其它组织层/边界的高度; 并产生相对于拟合表面的高程图。高程可以以各种方式显示，包括三维表面效果图，地形轮廓图，轮廓图，面孔颜色图和面对灰度图。也可以将高程组合并同时显示另一个组织层/边界依赖的图像数据集，以提供用于诊断的附加信息。

2. 发明申请

US20070216909A1 Methods for mapping tissue with optical coherence tomography data 有权
标题翻译：用光学相干断层扫描数据绘制组织的方法
公开(公告)号：US20070216909A1
公开(公告)日：2007-09-20
申请号：US11717263
申请日：2007-03-13
申请人： Matthew Everett , Paul Stetson , Scott Meyer , Shahram Dastmalchi , Jochen Straub
发明人： Matthew Everett , Paul Stetson , Scott Meyer , Shahram Dastmalchi , Jochen Straub
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： A61B3/10 , A61B3/00 , A61B3/102 , A61B5/0059 , A61B5/0066 , G01B9/02048 , G01B9/02089 , G01B9/02091 , G01N21/4795 , G06F19/00
摘要： Various methods are disclosed for mapping optical coherence tomography (OCT) data to facilitate review and diagnosis. In one aspect, high resolution 2D line scans are obtained along with lower density 3D cube scans and displayed in a manner to provide context to the clinician. In another aspect, OCT data is analyzed to provide information about non-uniformities of the tissue. Binary image maps of maps useful for determining tautness of membranes are also disclosed.
摘要翻译：公开了各种用于映射光学相干断层扫描（OCT）数据的方法以便于检查和诊断。在一个方面，获得高分辨率2D线扫描以及较低密度的3D立方体扫描，并以向临床医生提供上下文的方式显示。在另一方面，分析OCT数据以提供关于组织的非均匀性的信息。还公开了可用于确定膜紧张度的地图的二进制图像映射。

3. 发明申请

US20060072424A1 Patterned spinning disk based optical phase shifter for spectral domain optical coherence tomography 失效
标题翻译：用于光谱相干层析成像的基于旋转圆盘的光学移相器
公开(公告)号：US20060072424A1
公开(公告)日：2006-04-06
申请号：US10933795
申请日：2004-09-03
申请人： Matthew Everett , Scott Meyer , Yan Zhou
发明人： Matthew Everett , Scott Meyer , Yan Zhou
IPC分类号： G11B7/135
CPC分类号： A61B3/102 , A61B3/1005 , G01B9/02012 , G01B9/02044 , G01B9/02049 , G01B9/02069 , G01B9/02091 , G01B2290/35
摘要： A low cost patterned spinning disk is disclosed for achieving relatively rapid discrete optical phase shifts for an optical beam. The invention is particularly useful in a spectral domain optical coherence tomography system. The disk contains stepped patterns of different heights and/or refractive index distribution such that as it spins, an optical beam passing through or being reflected by the disk will experience different discrete optical phase delays. The disk can be operated as a phase shifter or it can be operated in synchronization with an intensity modulating chopper disk or a direct intensity modulation of the light source. The disk can also contain intensity modulating patterns such that both phase shifting and intensity modulation can be achieved at the same time. Various possible methods are also disclosed for the fabrication of the disk.
摘要翻译：公开了一种低成本图案旋转盘，用于实现光束的相对快速的离散光学相移。本发明在频域光学相干断层摄影系统中特别有用。盘包含不同高度和/或折射率分布的阶梯图案，使得当其旋转时，通过或被盘反射的光束将经历不同的离散光学相位延迟。磁盘可以作为移相器来操作，或者可以与强度调制斩波盘同步操作，也可以与光源进行直接强度调制。磁盘还可以包含强度调制模式，使得可以同时实现相移和强度调制。还公开了用于制造盘的各种可能的方法。

4. 发明申请

US20070291277A1 Spectral domain optical coherence tomography system 审中-公开
标题翻译：光谱光学相干断层扫描系统
公开(公告)号：US20070291277A1
公开(公告)日：2007-12-20
申请号：US11820773
申请日：2007-06-20
申请人： Matthew Everett , Scott Meyer , Martin Hacker , Jochen Horn , Christopher Baker , Kabir Arianta , James Foley , Jochen Straub , Yue Qiu , David Landhuis , Claus Flachenecker , Clement Viard
发明人： Matthew Everett , Scott Meyer , Martin Hacker , Jochen Horn , Christopher Baker , Kabir Arianta , James Foley , Jochen Straub , Yue Qiu , David Landhuis , Claus Flachenecker , Clement Viard
IPC分类号： G01B11/02 , G01B9/02
CPC分类号： G01B9/02077 , A61B3/102 , G01B9/0203 , G01B9/02044 , G01B9/02091 , G01B2290/65 , G01B2290/70 , G01N21/4795
摘要： An ophthalmic imaging device for improved ophthalmic imaging including: an optical coherence scanning device, a fundus imaging device: an iris viewer; a motorized chin rest; an internal test target, and a fixation target device wherein the optical coherence scanning device, the ophthalmic scanning device, the iris viewer, and the fixation target device all share at least one common optical element. The optical coherence device preferably employs a Mach-Zehnder interferometer with an all fiber reference path; monitoring and attenuating power within the reference path. The multiple devices are separately and in combination aligned with the eye. The system includes internal and external calibration and improved image formats.
摘要翻译：一种用于改进眼科成像的眼科成像装置，包括：光学相干扫描装置，眼底成像装置：虹膜观察者; 机动下巴休息; 内部测试对象和固定目标设备，其中光学相干扫描设备，眼科扫描设备，虹膜观察器和固定目标设备都共享至少一个公共光学元件。光学相干装置优选采用具有全光纤参考路径的马赫 - 策德尔干涉仪; 在参考路径内监测和衰减功率。多个装置是分开的并且与眼睛组合对准。该系统包括内部和外部校准和改进的图像格式。

5. 发明申请

US20060228011A1 Method and apparatus for measuring motion of a subject using a series of partial images from an imaging system 有权
公开(公告)号：US20060228011A1
公开(公告)日：2006-10-12
申请号：US11389351
申请日：2006-03-24
申请人： Matthew Everett , Claus Flachenecker , Martin Hacker , Scott Meyer , Keith O'Hara , Rick Williams
发明人： Matthew Everett , Claus Flachenecker , Martin Hacker , Scott Meyer , Keith O'Hara , Rick Williams
IPC分类号： G09G5/00 , G06K9/00
CPC分类号： A61B3/102 , A61B3/113
摘要： A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.

6. 发明申请

US20070152225A1 Optical broadband emitters and methods of making the same 失效
标题翻译：光纤宽带发射器及其制作方法
公开(公告)号：US20070152225A1
公开(公告)日：2007-07-05
申请号：US11322814
申请日：2005-12-29
申请人： Boon-Siew Ooi , Hery Djie , Yan Zhou , Scott Meyer
发明人： Boon-Siew Ooi , Hery Djie , Yan Zhou , Scott Meyer
IPC分类号： H01L29/15
CPC分类号： H01L33/0045 , B82Y20/00 , H01S5/026 , H01S5/0425 , H01S5/0602 , H01S5/22 , H01S5/34313 , H01S5/4031 , H01S5/50 , H01S2301/02 , H01S2301/04
摘要： An optical broadband emitter and the method of making such a broadband emitter are described. Intermixing of closely coupled multiple quantum wells, especially carrier tunneled coupled quantum wells, is described using nano-imprinting of a gel like dielectric layer such as a sol-gel derived SiO2 layer into multiple stepped or graded sections to form intermixing cap regions of different thickness. A thermal annealing process is performed to condense the SiO2 intermixing cap and induce intermixing. A superluminescent diode is described having multiple electrodes deposited over multiple sections of different bandgaps in which each individual electrode can be either forward or reverse biased to different degrees such that each diode section can individually function as a sub-band spontaneous emitter, an amplifier/attenuator, a photon-absorber, a transparent waveguide, or a photodetector/optical power monitor.
摘要翻译：描述了光学宽带发射器和制造这种宽带发射器的方法。使用诸如溶胶 - 凝胶衍生的SiO 2层之类的凝胶状电介质层将多个步进或分级部分的纳米压印描述为紧密耦合的多个量子阱，特别是载流子隧道耦合量子阱的混合以形成不同厚度的混合盖区域。进行热退火处理以冷凝SiO 2混合盖并引发混合。描述了一种超发光二极管，其具有沉积在不同带隙的多个部分上的多个电极，其中每个单独的电极可以被正向或反向偏置到不同的程度，使得每个二极管部分可以单独地用作子带自发发射极，放大器/衰减器光子吸收器，透明波导或光电检测器/光功率监视器。

7. 发明授权

US08489519B2 Apparatus, systems and methods for online, multi-parcel, multi-carrier, multi-service enterprise parcel shipping management 有权
标题翻译：用于在线，多包裹，多载体，多业务企业包裹运输管理的设备，系统和方法
公开(公告)号：US08489519B2
公开(公告)日：2013-07-16
申请号：US11510801
申请日：2006-08-24
申请人： Daniel F. Williams , David Allison Bennett , Lynn Shaindell Goldhaber , Dennis Glavin , Lory Elizabeth Krett , Charles D. Mentzer , Stephen M. Teglovic , John M. Dietz , William W. Smith, III , Paul Bilibin , Jinyue Liu , Paul R. McLaughlin , Scott Meyer , Sean Hu
发明人： Daniel F. Williams , David Allison Bennett , Lynn Shaindell Goldhaber , Dennis Glavin , Lory Elizabeth Krett , Charles D. Mentzer , Stephen M. Teglovic , John M. Dietz , William W. Smith, III , Paul Bilibin , Jinyue Liu , Paul R. McLaughlin , Scott Meyer , Sean Hu
IPC分类号： G06Q30/00 , G06F17/00 , G06G7/00
CPC分类号： G06Q10/0835 , G06Q10/08 , G06Q10/083 , G06Q10/0834 , G06Q10/08345 , G06Q10/10 , G06Q10/101 , G06Q30/0282 , G06Q30/0601
摘要： The present invention provides a plurality of Enterprises with a single online user interface with which the Enterprise can provide Enterprise Shippers, shipping origination users and shipping intermediary users with an automated parcel management system for a plurality of supported Carriers for a plurality of services. The present invention provides for the hierarchical definition of users, including the establishment of at least one user for each Enterprise as a Super-Administrator with the highest level of privileges and authority for the Enterprise, and the identification of other users as Sub-Administrators, Desktop Users and Shipping Station Users. The present invention also provides for the hierarchical definition of organizational units within each Enterprise, including the definition of sites, groups within a site, and users within a group and for a distinct definition of policies, privileges, and other types of specifications for each user level, each user, and each organizational unit.
摘要翻译：本发明提供了具有单个在线用户界面的多个企业，企业可以通过该企业提供企业托运人，为起始用户和运输中间用户提供用于多个服务的多个被支持运营商的自动包裹管理系统。本发明提供了用户的分层定义，包括为每个企业建立至少一个具有企业级别的权限和权限的超级管理员的用户，以及将其他用户识别为子管理员，桌面用户和航运站用户。本发明还提供了每个企业内的组织单位的分层定义，包括站点的定义，站点内的组以及组内的用户以及针对每个用户的策略，特权和其他类型的规范的明确定义级别，每个用户和每个组织单位。

8. 发明授权

US08321002B2 Arrhythmia discrimination using ECG's sensed from multiple implanted electrodes 有权
标题翻译：使用从多个植入电极感测的心电图进行心律失常辨别
公开(公告)号：US08321002B2
公开(公告)日：2012-11-27
申请号：US13027608
申请日：2011-02-15
申请人： Yi Zhang , Carlos A. Ricci , Jeffrey E. Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
发明人： Yi Zhang , Carlos A. Ricci , Jeffrey E. Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
IPC分类号： A61B5/0464
CPC分类号： A61B5/04011 , A61B5/7203
摘要： Cardiac monitoring and/or stimulation methods and systems provide for monitoring, diagnosing, defibrillation and pacing therapies, or a combination of these capabilities, including cardiac systems incorporating or cooperating with neuro-stimulating devices, drug pumps, or other therapies. Embodiments of the present invention relate generally to implantable medical devices employing automated cardiac activation sequence monitoring and/or tracking for arrhythmia discrimination. Embodiments of the invention are directed to devices and methods involving sensing a plurality of composite cardiac signals using a plurality of implantable electrodes. A source separation is performed using the sensed plurality of composite cardiac signals and the separation produces one or more cardiac signal vectors associated with one or more cardiac activation sequences that is indicative of ischemia. A change of the one or more cardiac signal vectors is detected using the one or more cardiac signal vectors. Cardiac arrhythmias are discriminated using the one or more cardiac signal vectors.
摘要翻译：心脏监测和/或刺激方法和系统提供监测，诊断，除颤和起搏治疗，或这些能力的组合，包括结合或与神经刺激装置，药物泵或其他疗法组合的心脏系统。本发明的实施方案一般涉及使用自动心脏激活序列监测和/或跟踪用于心律失常鉴别的可植入医疗装置。本发明的实施例涉及使用多个可植入电极感测多个复合心脏信号的装置和方法。使用感测的多个复合心脏信号进行源分离，并且分离产生与指示缺血的一个或多个心脏激活序列相关联的一个或多个心脏信号载体。使用一个或多个心脏信号矢量检测一个或多个心脏信号矢量的改变。使用一个或多个心脏信号载体来区分心律失常。

9. 发明授权

US08145296B2 Adaptive windowing for cardiac waveform discrimination 有权
标题翻译：心脏波形鉴别的自适应窗口
公开(公告)号：US08145296B2
公开(公告)日：2012-03-27
申请号：US12538297
申请日：2009-08-10
申请人： Kevin J. Stalsberg , Yanting Dong , Scott Meyer , Eric K. Enrooth , Derek D. Bohn
发明人： Kevin J. Stalsberg , Yanting Dong , Scott Meyer , Eric K. Enrooth , Derek D. Bohn
IPC分类号： A61B5/042
CPC分类号： A61N1/371 , A61B5/04525 , A61B5/0472 , A61B5/7217
摘要： Cardiac devices and methods provide adaptation of detection windows used to determine a cardiac response to pacing. Adapting a detection window involves sensing a cardiac signal indicative of a particular type of cardiac pacing response, and detecting a feature of the sensed cardiac signal. The cardiac response detection window associated with the type of cardiac pacing response is preferentially adjusted based on the location of the detected cardiac feature. Preferential adjustment of the detection window may involve determining a direction of change between the detection window and the detected feature. The detection window may be adapted more aggressively in a more preferred direction and less aggressively in a less preferred direction.
摘要翻译：心脏装置和方法提供用于确定对起搏的心脏反应的检测窗口的适应。适应检测窗口包括感测指示特定类型的心脏起搏反应的心脏信号，以及检测感测到的心脏信号的特征。基于检测到的心脏特征的位置优先调整与心脏起搏响应类型相关联的心脏响应检测窗口。检测窗口的优先调整可以包括确定检测窗口和检测到的特征之间的变化方向。检测窗口可以在更优选的方向上更积极地改变，并且在较不优选的方向上较不积极地适配。

10. 发明申请

US20080166208A1 WET CLEAN SYSTEM DESIGN 失效
标题翻译：湿清洁系统设计
公开(公告)号：US20080166208A1
公开(公告)日：2008-07-10
申请号：US11620610
申请日：2007-01-05
申请人： Paul Lester , Scott Meyer , Wyland L. Atkins , Douglas Richards , Constantin Predoaica , Jeffrey Hudgens , Charles Carlson , Penchala Kankanala , Mike Rice , James S. Papanu , Evanson G. Baiya , John J. Rosato
发明人： Paul Lester , Scott Meyer , Wyland L. Atkins , Douglas Richards , Constantin Predoaica , Jeffrey Hudgens , Charles Carlson , Penchala Kankanala , Mike Rice , James S. Papanu , Evanson G. Baiya , John J. Rosato
IPC分类号： H01L21/67
CPC分类号： H01L21/67766 , H01L21/67051 , H01L21/68707 , Y10S134/902
摘要： The present invention generally provides an apparatus and method for processing and transferring substrates in a multi-chamber processing system that has the capability of receiving and performing single substrate processing steps performed in parallel, while using the many favorable aspects of batch processing. Embodiments of the invention described herein are adapted to maximize system throughput, reduce system cost, reduce cost per substrate during processing, increase system reliability, improve the device yield on the processed substrates, and reduce system footprint. In one embodiment, the cluster tool is adapted to perform a wet/clean process sequence in which various substrate cleaning processes are performed on a substrate in the cluster tool.
摘要翻译：本发明通常提供了一种在多室处理系统中处理和传送基板的装置和方法，该多室处理系统具有在使用批处理的许多有利方面的同时并行执行的单个基板处理步骤的能力。本文描述的本发明的实施例适用于最大化系统吞吐量，降低系统成本，在处理期间降低每个基板的成本，增加系统可靠性，提高处理的基板上的装置产量，并减少系统占用面积。在一个实施例中，群集工具适于执行湿/清洁处理序列，其中在群集工具中的基板上执行各种基板清洁处理。

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