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1. 发明申请

US20060058299A1 N-2s-4-3,4-difluorobenzyl morpholin-2yl methyl -2-(3-methylsulphonyl amino!phenyl acetamide as ccr3 antagonist for the treatment of inflammatory conditions 审中-公开
标题翻译： N-2s-4-3,4-二氟苄基吗啉-2-基甲基-2-（3-甲基磺酰基氨基苯基乙酰胺）作为治疗炎性病症的ccr3拮抗剂
公开(公告)号：US20060058299A1
公开(公告)日：2006-03-16
申请号：US10509417
申请日：2003-03-27
申请人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
发明人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
IPC分类号： C07D265/30 , A61K31/537
CPC分类号： C07D265/30 , A61K31/5375
摘要： Compound of formula (I): and salts and solvates thereof, a process for its preparation, pharmaceutical formulations containing it and its use in therapy.
摘要翻译：式（I）化合物：

2. 发明申请

US20060063765A1 Novel compounds 有权
标题翻译：新型化合物
公开(公告)号：US20060063765A1
公开(公告)日：2006-03-23
申请号：US10509162
申请日：2003-03-27
申请人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
发明人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
IPC分类号： A61K31/537 , C07D265/30
CPC分类号： C07D413/12 , C07D413/14 , C07D417/12
摘要： Compounds of formula (I): wherein: R1 represents substituted or unsubstituted heteroaryl; Y represents —(CRnaRnb)n—; Rna and Rnb are each independently hydrogen or C1-6alkyl; n is an integer from 0 to 5; R2 represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3 and R4 each independently represent hydrogen or C1-6alkyl; R7 represents hydrogen or C1-6alkyl; R8 represents hydrogen or C1-6alkyl; and salts and solvates thereof; are CCR3 antagonists and are thus indicated to be useful in therapy.
摘要翻译：式（I）的化合物：

3. 发明申请

US20050222147A1 Process for the preparation of morpholine derivatives and intermediates therefore 审中-公开
标题翻译：因此，制备吗啉衍生物和中间体的方法
公开(公告)号：US20050222147A1
公开(公告)日：2005-10-06
申请号：US10509519
申请日：2003-03-27
申请人： Martin Hayes , Gail Mills , Stephen Swanson , Andrew Walker , Mark Wilkinson
发明人： Martin Hayes , Gail Mills , Stephen Swanson , Andrew Walker , Mark Wilkinson
IPC分类号： A61K31/5375 , A61K31/5377 , A61P1/04 , A61P3/10 , A61P9/10 , A61P9/14 , A61P11/02 , A61P11/06 , A61P17/00 , A61P17/04 , A61P17/06 , A61P19/02 , A61P25/00 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/18 , A61P33/00 , A61P33/02 , A61P33/10 , A61P33/12 , A61P37/02 , A61P37/06 , C07D265/30 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D413/02
CPC分类号： C07D265/30 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Processes for the preparation of a compound of formula (IIIA) or a salt thereof are disclosed.
摘要翻译：公开了制备式（IIIA）化合物或其盐的方法。

4. 发明授权

US07622464B2 Morpholinyl-urea derivatives for use in the treatment of inflammatory diseases 有权
标题翻译：用于治疗炎性疾病的吗啉基 - 脲衍生物
公开(公告)号：US07622464B2
公开(公告)日：2009-11-24
申请号：US10509162
申请日：2003-03-27
申请人： Rachael Ann Ancliff , Caroline Mary Cook , Colin David Eldred , Paul Martin Gore , Lee Andrew Harrison , Martin Alistair Hayes , Simon Teanby Hodgson , Duncan Bruce Judd , Suzanne Elaine Keeling , Xiao Qing Lewell , Gail Mills , Graeme Michael Robertson , Stephen Swanson , Andrew John Walker , Mark Wilkinson
发明人： Rachael Ann Ancliff , Caroline Mary Cook , Colin David Eldred , Paul Martin Gore , Lee Andrew Harrison , Martin Alistair Hayes , Simon Teanby Hodgson , Duncan Bruce Judd , Suzanne Elaine Keeling , Xiao Qing Lewell , Gail Mills , Graeme Michael Robertson , Stephen Swanson , Andrew John Walker , Mark Wilkinson
IPC分类号： A61K31/535 , C07D413/14 , C07D413/12
CPC分类号： C07D413/12 , C07D413/14 , C07D417/12
摘要： Compounds of formula (I): wherein: R1 represents substituted or unsubstituted heteroaryl; Y represents —(CRnaRnb)n—; Rna and Rnb are each independently hydrogen or C1-6alkyl; n is an integer from 0 to 5; R2 represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3 and R4 each independently represent hydrogen or C1-6-alkyl; R7 represents hydrogen or C1-6alkyl; R8 represents hydrogen or C1-6alkyl; and salts and solvates thereof; are CCR3 antagonists and are thus indicated to be useful in therapy.
摘要翻译：式（I）化合物：其中：R 1表示取代或未取代的杂芳基; Y表示 - （CRnaRnb）n-; Rna和Rnb各自独立地为氢或C 1-6烷基; n为0〜5的整数， R2表示未取代或取代的芳基或未取代或取代的杂芳基; R3和R4各自独立地表示氢或C1-6烷基; R 7表示氢或C 1-6烷基; R8代表氢或C1-6烷基; 其盐和溶剂合物; 是CCR3拮抗剂，因此被认为可用于治疗。

5. 发明申请

US20060089497A1 Benzenesulphonate salt of a morpholine urea derivative for use as a ccr-3 antagonist in the treatment of inflammatory conditions 失效
标题翻译：用作治疗炎性病症的ccr-3拮抗剂的吗啉脲衍生物的苯磺酸盐
公开(公告)号：US20060089497A1
公开(公告)日：2006-04-27
申请号：US10509521
申请日：2003-03-27
申请人： John Cook , Robert Landon , Andrew Walker , Mark Wilkinson
发明人： John Cook , Robert Landon , Andrew Walker , Mark Wilkinson
IPC分类号： C07D265/30 , C07C215/28
CPC分类号： C07D265/30
摘要： Compounds of formula (I): wherein A− represents the benzenesulphonate (besylate) anion; R represents H or C1-6 alkyl; and n is a number from 0.8 to 2.2 are CCR3 antagonists and are therefore indictated to be useful in therapy are described.
摘要翻译：式（I）的化合物：其中A表示苯磺酸盐（苯磺酸盐）阴离子; R代表H或C 1-6烷基; 并且n是0.8至2.2的数字是CCR3拮抗剂，因此被指示可用于治疗。

6. 发明申请

US20070170657A1 Stuffing box bushing, assembly and method of manufacture 审中-公开
标题翻译：填料箱衬套，组装和制造方法
公开(公告)号：US20070170657A1
公开(公告)日：2007-07-26
申请号：US11336143
申请日：2006-01-20
申请人： Mark Wilkinson
发明人： Mark Wilkinson
IPC分类号： F16J15/00
CPC分类号： F16J15/183 , F04D29/106
摘要： A one-piece bushing to be inserted into the seal cavity of a rotary mechanical device includes a one-piece cylindrical bushing element with a single slit to allow easy installation over the shaft. The bushing is a substantially cylindrical semi-rigid member with an inner bore closely approximating the outer diameter of the shaft and includes a groove at the motor end on the outer surface and a corresponding groove on the inner surface to provide a lantern ring. Milling slots or other types of relief are formed on one surface of a flat piece of material to allow for shaping into cylindrical form and to provide for easy installation over an installed device shaft. Seal water openings are provided between the outer groove and inner groove of the bushing to form a lantern ring. Generally, two or three packing rings are added on the motor side to complete the shaft sealing system for installation in the seal cavity.
摘要翻译：插入到旋转机械装置的密封腔中的一体式衬套包括具有单个狭缝的一体式圆柱形衬套元件，以允许容易地安装在轴上。衬套是基本上圆柱形的半刚性构件，其内孔与轴的外径接近，并且包括位于外表面上的马达端处的凹槽和内表面上的相应凹槽，以提供一个灯笼环。铣削槽或其他类型的浮雕形成在平坦材料的一个表面上，以允许成形为圆柱形，并提供容易安装在安装的装置轴上。密封水开口设置在衬套的外槽和内槽之间，形成一个灯环。通常，在电动机一侧加入两个或三个填料环，以完成安装在密封腔中的轴封系统。

7. 外观设计

USD446253S1 Board game 失效
标题翻译：棋盘游戏
公开(公告)号：USD446253S1
公开(公告)日：2001-08-07
申请号：US29129661
申请日：2000-09-19
申请人： Mark Wilkinson , Joan Wilkinson
设计人： Mark Wilkinson , Joan Wilkinson

8. 发明授权

US09555552B2 Trimmer line cutting device and method 有权
标题翻译：微调线切割装置及方法
公开(公告)号：US09555552B2
公开(公告)日：2017-01-31
申请号：US13478606
申请日：2012-05-23
申请人： David B. Skinner , Mark Wilkinson
发明人： David B. Skinner , Mark Wilkinson
IPC分类号： B26D3/16 , B26D7/01
CPC分类号： B26D3/16 , B26D1/085 , B26D7/01 , B26D7/14
摘要： A cutting device includes a body and a cutting blade assembly. The cutting blade assembly includes a cutting blade having a cutting edge and is reciprocally secured to the body. Movement of the cutting blade assembly from a retracted position to an engaged position causes the cutting edge to engage a line, such as a monofilament trimmer line, to cut the line to a desired length. Tension may be created in the line prior to cutting by positioning the line in a non-linear trough in the body.
摘要翻译：切割装置包括主体和切割刀片组件。切割刀片组件包括具有切割刃的切割刀片并且相互固定在本体上。切割刀片组件从缩回位置到接合位置的移动使得切割边缘接合诸如单丝修剪线的线，以将线切割成期望的长度。通过将线定位在身体中的非线性槽中，可以在切割之前的线中产生张力。

9. 发明申请

US20120297626A1 Trimmer Line Cutting Device and Method 有权
标题翻译：微调线切割装置及方法
公开(公告)号：US20120297626A1
公开(公告)日：2012-11-29
申请号：US13478606
申请日：2012-05-23
申请人： David B. Skinner , Mark Wilkinson
发明人： David B. Skinner , Mark Wilkinson
IPC分类号： B26D3/16 , B26D7/14
CPC分类号： B26D3/16 , B26D1/085 , B26D7/01 , B26D7/14
摘要： A cutting device includes a body and a cutting blade assembly. The cutting blade assembly includes a cutting blade having a cutting edge and is reciprocally secured to the body. Movement of the cutting blade assembly from a retracted position to an engaged position causes the cutting edge to engage a line, such as a monofilament trimmer line, to cut the line to a desired length. Tension may be created in the line prior to cutting by positioning the line in a non-linear trough in the body.
摘要翻译：切割装置包括主体和切割刀片组件。切割刀片组件包括具有切割刃的切割刀片并且相互固定在本体上。切割刀片组件从缩回位置到接合位置的移动使得切割边缘接合诸如单丝修剪线的线，以将线切割成期望的长度。通过将线定位在身体中的非线性槽中，可以在切割之前的线中产生张力。

10. 发明授权

US07725388B2 Verification of electronic financial transactions 有权
标题翻译：验证电子金融交易
公开(公告)号：US07725388B2
公开(公告)日：2010-05-25
申请号：US10430361
申请日：2003-05-05
申请人： Mark Wilkinson
发明人： Mark Wilkinson
IPC分类号： G06Q30/00
CPC分类号： G07F7/1008 , G06F21/36 , G06F21/83 , G06Q20/10 , G06Q20/102 , G06Q20/341 , G06Q20/40 , G07C9/00142 , G07F7/10 , G07F7/1041 , G07F7/1083
摘要： Techniques are provided for verifying an electronic financial transaction. In certain implementations, verifying an electronic financial transaction includes generating a user interface including a security code, the user interface associating different portions of the code with different parts of a user input device, and associating at least one code portion with a user input device part having visual indicia dissimilar to the visual representation of the code portion. Verifying an electronic financial transaction also includes detecting activation of the user input device in a manner that generates a code, and determining whether the generated code corresponds to the security code.
摘要翻译：提供了用于验证电子金融交易的技术。在某些实现中，验证电子金融交易包括生成包括安全代码的用户界面，所述用户界面将代码的不同部分与用户输入设备的不同部分相关联，并且将至少一个代码部分与用户输入设备部分相关联具有与代码部分的视觉表示不相似的视觉标记。验证电子金融交易还包括以生成代码的方式检测用户输入设备的激活，并且确定生成的代码是否对应于安全代码。

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