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1. 发明申请

US20060063765A1 Novel compounds 有权
标题翻译：新型化合物
公开(公告)号：US20060063765A1
公开(公告)日：2006-03-23
申请号：US10509162
申请日：2003-03-27
申请人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
发明人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
IPC分类号： A61K31/537 , C07D265/30
CPC分类号： C07D413/12 , C07D413/14 , C07D417/12
摘要： Compounds of formula (I): wherein: R1 represents substituted or unsubstituted heteroaryl; Y represents —(CRnaRnb)n—; Rna and Rnb are each independently hydrogen or C1-6alkyl; n is an integer from 0 to 5; R2 represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3 and R4 each independently represent hydrogen or C1-6alkyl; R7 represents hydrogen or C1-6alkyl; R8 represents hydrogen or C1-6alkyl; and salts and solvates thereof; are CCR3 antagonists and are thus indicated to be useful in therapy.
摘要翻译：式（I）的化合物：

2. 发明申请

US20060266602A1 Shock absorber assembly 有权
标题翻译：减震器总成
公开(公告)号：US20060266602A1
公开(公告)日：2006-11-30
申请号：US10567947
申请日：2004-08-12
申请人： Graeme Robertson
发明人： Graeme Robertson
IPC分类号： F16F9/34
CPC分类号： F16F9/063
摘要： A shock absorber assembly includes a motion damping means that is filled with a fluid in operation and has a pair of relatively moveable parts (12, 14) and valve means (26) permitting flow of the fluid between the parts. The parts comprise a first part (12) and a second part (14) in which the first part is receivable whereby the parts are arranged for relative retracting and extending movement during which fluid is forced through the valve means (26) at respective predetermined controlled flow rates so as to dampen the movement. The relatively moveable parts contain respective primary chambers (24, 29) for the fluid. The first part is substantially smaller in cross-section than the second part to define an intermediate chamber (52) about the first part within the second part. Lateral port means (56) communicates the intermediate chamber (52) and the primary chamber (24) of first part (12). The flows at respective predetermined controlled flow rates are limited to respective flows (i) directly from the primary chamber (24) of the first part (12) to the primary chamber (29) of the second part (14) and (ii) via the intermediate chamber (52) and lateral port means (56) from the primary chamber (29) of the second part (14) to the primary chamber (24) of the first part (12).
摘要翻译：减震器组件包括运动阻尼装置，其在运行中填充有流体，并且具有一对相对可移动的部件（12,14）和阀装置（26），允许流体在部件之间流动。这些部件包括第一部分（12）和第二部分（14），第一部分（12）和第二部分（14）中的第一部分可接收，由此部件布置成用于相对缩回和延伸运动，在该过程中流体被强制通过阀装置（26）流量以抑制运动。相对可移动的部件包含用于流体的相应的主室（24,29）。第一部分的横截面显着小于第二部分，以限定第二部分内的第一部分周围的中间室（52）。横向端口装置（56）连通第一部分（12）的中间室（52）和主室（24）。在各个预定的受控流速下的流量被限制到直接从第一部分（12）的主室（24）到第二部分（14）的主室（29）的相应流（i）和（ii）中间室（52）和从第二部分（14）的主室（29）到第一部分（12）的主室（24）的侧向端口装置（56）。

3. 发明申请

US20060158806A1 Single power source for serially connectable devices 审中-公开
标题翻译：单电源，用于可串行连接的设备
公开(公告)号：US20060158806A1
公开(公告)日：2006-07-20
申请号：US11049504
申请日：2005-02-02
申请人： Graeme Robertson
发明人： Graeme Robertson
IPC分类号： H02H3/00
CPC分类号： G06F1/266 , G11B33/12
摘要： There is disclosed a serially connectable device (200) for acting as a master device to control power usage by itself and one or more other serially connectable devices comprising a power input port (208) through which power is supplied to the serially connectable device (200), an output serial power connector (206) for supplying power and power control signals to any other serially connectable device or devices connected via said first serial power connector to the supply of power received through said power input port (200), and a microcontroller (216) for controlling power usage by one or more internal components (218,222) of the serially connectable device and for producing control signals to control power usage by any other device or devices connected in series with said serially connectable device.
摘要翻译：公开了一种可串行连接的装置（200），其用作主装置以控制其自身的功率使用以及一个或多个其它可串行连接的装置，其包括电力输入端口（208），电力供应给可串行连接的装置（200 ），用于向通过所述第一串行电源连接器连接的任何其它可串行连接的设备或设备向通过所述电力输入端口（200）接收的电力供应提供电力和功率控制信号的输出串行电源连接器（206）（216），用于控制可串行连接的设备的一个或多个内部部件（218,222）的功率使用，并产生控制信号，以控制与所述可串行连接的设备串联连接的任何其他设备或设备的功率使用。

4. 发明申请

US20060091591A1 Suspension system 审中-公开
标题翻译：悬挂系统
公开(公告)号：US20060091591A1
公开(公告)日：2006-05-04
申请号：US11305658
申请日：2005-12-16
申请人： Graeme Robertson
发明人： Graeme Robertson
IPC分类号： F16F9/14
CPC分类号： B60G3/20 , B60G7/008 , B60G7/02 , B60G13/003 , B60G13/005 , B60G17/0424 , B60G21/073 , B60G2200/14 , B60G2200/18 , B60G2202/154 , B60G2202/24 , B60G2204/13 , B60G2204/143 , B60G2204/148 , B60G2204/421 , B60G2206/422 , B60G2600/08 , F16F9/063 , F16F9/36
摘要： A suspension unit (110) for a suspension system has an accumulator (12) for holding and maintaining a fluid such as a gas under pressure. The accumulator is associated with a motion damping unit (114) that is filled with a fluid, such as an oil, in operation. The accumulator includes a floating piston (122) that separates a first chamber (120) in which is stored the pressurised gas, and a second chamber (124) for storing the other fluid under pressure. A third chamber (128) in the motion damping unit (114) is in fluid flow communication with the second chamber (124) of said accumulator through valve means (126) controlling the flow of fluid between the chambers. Relative movement between the accumulator (112) and said motion damping unit (114) causes fluid to flow from the second chamber (124) of the accumulator (112) through the valve (126) to the third chamber (128) whereby gas pressure in said first chamber (120) moves the floating piston (122) in the accumulator thereby reducing the gas pressure in said first chamber. A side chamber (152) within said motion damping unit (114) also expands and contracts with said relative retracting and extending movement of said accumulator (112) and the motion damping unit (114). At least one bleed port (156) communicates the side chamber (152) with the second chamber (124), the bleed port (156) restricting the flow of fluid between the side chamber (152) and the second chamber (124) thereby assisting control of the relative movement of the accumulator (112) and the motion damping unit (114).
摘要翻译：用于悬架系统的悬挂单元（110）具有用于保持和保持流体（例如在压力下的气体）的蓄能器（12）。蓄能器与运行阻尼单元（114）相关联，运动阻尼单元（114）在操作中填充有诸如油的流体。蓄能器包括分离其中存储有加压气体的第一室（120）的浮动活塞（122）和用于在压力下储存其它流体的第二室（124）。运动阻尼单元（114）中的第三腔室（128）通过阀装置（126）与所述蓄能器的第二腔室（124）流体连通，从而控制腔室之间的流体流动。蓄能器（112）和所述运动阻尼单元（114）之间的相对运动导致流体从蓄能器（112）的第二腔室（124）流过阀门（126）流到第三腔室（128），由此气体压力所述第一室（120）将浮动活塞（122）移动到蓄能器中，从而减小所述第一室中的气体压力。所述运动阻尼单元（114）内的侧室（152）还随所述蓄能器（112）和运动阻尼单元（114）的所述相对缩回和延伸运动而膨胀和收缩。至少一个排出口（156）将侧室（152）与第二室（124）连通，排出口（156）限制侧室（152）和第二室（124）之间的流体流从而辅助控制蓄能器（112）和运动阻尼单元（114）的相对运动。

5. 发明申请

US20060079525A1 Morpholin-acetamide derivatives for the treatment of inflammatory diseases 有权
标题翻译：吗啉 - 乙酰胺衍生物用于治疗炎性疾病
公开(公告)号：US20060079525A1
公开(公告)日：2006-04-13
申请号：US11284544
申请日：2005-11-22
申请人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Graeme Robertson , Stephen Swanson
发明人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Graeme Robertson , Stephen Swanson
IPC分类号： A61K31/537 , C07D265/30
CPC分类号： C07D265/30 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： There are provided according to the invention, novel compounds of formula (I) wherein R1, R2, R3, R4, R5, X, a, b and Z are as defined in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译：根据本发明，提供了式（I）的新化合物，其中R 1，R 2，R 3，R 3， 4，R 5，X，a，b和Z如说明书中所定义，制备方法，含有它们的制剂及其在治疗炎性疾病中的用途。

6. 发明申请

US20060058299A1 N-2s-4-3,4-difluorobenzyl morpholin-2yl methyl -2-(3-methylsulphonyl amino!phenyl acetamide as ccr3 antagonist for the treatment of inflammatory conditions 审中-公开
标题翻译： N-2s-4-3,4-二氟苄基吗啉-2-基甲基-2-（3-甲基磺酰基氨基苯基乙酰胺）作为治疗炎性病症的ccr3拮抗剂
公开(公告)号：US20060058299A1
公开(公告)日：2006-03-16
申请号：US10509417
申请日：2003-03-27
申请人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
发明人： Rachael Ancliff , Caroline Cook , Colin Eldred , Paul Gore , Lee Harrison , Martin Hayes , Simon Hodgson , Duncan Judd , Suzanne Keeling , Xiao Lewell , Gail Mills , Graeme Robertson , Stephen Swanson , Andrew Walker , Mark Wilkinson
IPC分类号： C07D265/30 , A61K31/537
CPC分类号： C07D265/30 , A61K31/5375
摘要： Compound of formula (I): and salts and solvates thereof, a process for its preparation, pharmaceutical formulations containing it and its use in therapy.
摘要翻译：式（I）化合物：

7. 发明授权

US06794439B1 Acrylic polymer composition 有权
标题翻译：丙烯酸聚合物组合物
公开(公告)号：US06794439B1
公开(公告)日：2004-09-21
申请号：US09744162
申请日：2001-01-22
申请人： Graeme Robertson , Ian Muir Fraser
发明人： Graeme Robertson , Ian Muir Fraser
IPC分类号： C08K336
CPC分类号： C08F292/00 , C08K3/22 , C08L33/066
摘要： An abrasion resistant acrylic composition comprises at least 70% w/w of the residues of at least one polmerisable acrylic monomer, 0.2-5% w/w of a finely divided compound comprising at least one oxide selected from silicon, titanium, zirconium and aluminum oxides, and 0.2-25% w/w of at least one linking compound which is miscible with said polymerisable acrylic monomer and which is capable of bonding to the surface of the oxide compound. The acrylic composition may be thermoformed while retaining its abrasion resistant surface properties.
摘要翻译：耐磨性丙烯酸组合物包含至少70％w / w的至少一种可聚合丙烯酸类单体的残余物，0.2-5％w / w的细分化合物，其包含至少一种选自硅，钛，锆和铝的氧化物氧化物和0.2-25％w / w的至少一种与所述可聚合的丙烯酸类单体混溶并且能够结合到氧化物化合物的表面的连接化合物。丙烯酸组合物可以热成型，同时保持其耐磨性表面性质。

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