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    • 1. 发明申请
    • Optical Multiplexer/Demultiplexer
    • 光复用器/解复用器
    • US20080285974A1
    • 2008-11-20
    • US12120680
    • 2008-05-15
    • Makoto TakahashiYasunobu MatsuokaMasahiro Aoki
    • Makoto TakahashiYasunobu MatsuokaMasahiro Aoki
    • H04J14/02
    • G02B6/29365G02B6/29367G02B6/2938G02B6/42G02B6/4246
    • An optical multiplexer/demultiplexer comprising a member, of which first and second opposite planar surfaces are parallel to each other. The member includes therein a void, of which third and fourth opposite planar surfaces are in parallel to each other. An extension of a first line lying on the first planar surface and an extension of a third line lying on the third planar surface intersect each other in a cross section including the void of the member, a smaller one of intersection angles thereof being φ1. An extension of a second line lying on the second planar surface and an extension of a fourth line lying on the fourth planar surface intersect each other, a smaller one of intersection angles thereof being φ1. The third planar surface is provided on a part thereof with at least one high reflection coating film. The fourth planar surface is provided on a part thereof with at least one optical wavelength filter. At least parts of the high reflection coating film and the first optical wavelength filter are opposed to each other. The first optical wavelength filter transmits therethrough light of wavelength λ1 and reflects light of wavelength λ2 (here, wavelength λ1≠wavelength λ2). The member and an interior of the void are different in value of refractive index from each other.
    • 一种光信号多路复用器/解复用器,包括一第一和第二相对平面彼此平行的部件。 该构件包括其中第三和第四相对平面彼此平行的空隙。 位于第一平坦表面上的第一线的延伸部和位于第三平坦表面上的第三线的延伸线在包括构件的空隙的横截面中彼此相交,较小的一个相交角为φ1。 位于第二平坦表面上的第二线的延伸部和位于第四平坦表面上的第四线的延伸部彼此相交,较小的一个相交角为φ1。第三平面设置在其一部分上 与至少一个高反射涂膜。 第四平面在其一部分上设置有至少一个光波长滤波器。 高反射涂膜和第一光波长滤光片的至少一部分彼此相对。 第一光学波长滤波器透过波长为λ1的光并且反射波长λ2的光(这里,波长λ1 <>波长λ2)。 空隙的构件和内部的折射率值彼此不同。
    • 8. 发明授权
    • Wavelength tunable filter and wavelength tunable laser module
    • 波长可调滤波器和波长可调激光模块
    • US08179931B2
    • 2012-05-15
    • US12622785
    • 2009-11-20
    • Hideo ArimotoMasahiro Aoki
    • Hideo ArimotoMasahiro Aoki
    • H01S3/10
    • G02F1/3133H01S5/06256H01S5/1032H01S5/1035
    • A wavelength tunable filter and a wavelength tunable laser module are a codirectional coupler type whose characteristics do not vary significantly with a process error. They are structured so as to include a semiconductor substrate which has a first optical waveguide and a second optical waveguide. The first and the second optical waveguides are extended from a first side of the semiconductor substrate to an opposing second side thereof. The first optical waveguide includes a first core layer, which has a planar layout having periodic convexes and concaves, and a pair of electrodes, which vertically sandwich the first core layer. The second optical waveguide includes a second core layer, which has a lower refractive index than the first core layer. Further, a layer having the same composition and film thickness as the second core layer is placed under the first core layer.
    • 波长可调滤波器和波长可调激光器模块是一种同向耦合器类型,其特性与处理误差不会显着变化。 它们被构造成包括具有第一光波导和第二光波导的半导体衬底。 第一和第二光波导从半导体衬底的第一侧延伸到相对的第二侧。 第一光波导包括具有周期性凸起和凹陷的平面布局的第一芯层和垂直夹着第一芯层的一对电极。 第二光波导包括具有比第一芯层低的折射率的第二芯层。 此外,具有与第二芯层相同的组成和膜厚度的层被放置在第一芯层下方。
    • 10. 发明申请
    • Method Of Producing Compound Having Anti-Hcv Activity
    • 生产具有抗Hcv活性的化合物的方法
    • US20110098477A1
    • 2011-04-28
    • US11988003
    • 2006-06-27
    • Masahiro AokiYoshie NagahashiHideyuki KatoTatsuya ItoMiyako MasubuchiToru Okuda
    • Masahiro AokiYoshie NagahashiHideyuki KatoTatsuya ItoMiyako MasubuchiToru Okuda
    • C07D213/55C07C229/36C12P13/04
    • C07C229/36C07C231/14C12P13/02C07C235/76
    • There is provided a convenient and inexpensive method of producing a compound which has a high activity of inhibiting replication of hepatitis C virus (HCV) and is useful for preventing and treating a liver disease caused by HCV infection.It is a method of biologically producing a compound represented by the formula (1): [wherein A represents a hydrogen atom, a straight or branched alkyl group having 1 to 8 carbon atoms, or the like], or a pharmaceutically acceptable salt thereof, a method comprising adding an amino acid derivative represented by the formula (3): [wherein A has the same meaning as defined for the compound of the above formula (1); and R represents a hydrogen atom, a straight or branched alkyl group having 1 to 8 carbon atoms, or the like], or a salt thereof into the fungal mycelium or the culture medium/culture broth of a filamentous fungal strain having an ability to produce the compound represented by the formula (2): to thereby cause the fungal strain to directly produce the compound of the formula (1).
    • 提供了一种方便且廉价的生产具有抑制丙型肝炎病毒(HCV)复制活性的化合物的方法,并且可用于预防和治疗由HCV感染引起的肝脏疾病。 生物地制造式(1)表示的化合物或其药学上可接受的盐的方法:[其中A表示氢原子,碳原子数1〜8的直链或支链烷基等] 包括加入由式(3)表示的氨基酸衍生物的方法:[其中A具有与上述式(1)的化合物相同的含义; R表示氢原子,碳原子数为1〜8的直链或支链烷基等,或其盐形成具有生产能力的丝状真菌菌株的真菌菌丝体或培养液/培养液 由式(2)表示的化合物:由此使真菌菌株直接生成式(1)的化合物。