会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明申请
    • REDUCTION OF ENDOTOXIN IN POLYSIALIC ACIDS
    • 减少多糖中的内毒素
    • US20110159130A1
    • 2011-06-30
    • US12528763
    • 2008-02-28
    • Sanjay JainPeter LaingGregory Gregoriadis
    • Sanjay JainPeter LaingGregory Gregoriadis
    • A61K35/74C07K14/00C12P21/06
    • C08B37/0006B01D15/363C08B37/0003
    • The present invention relates to process for reducing the endotoxin content of a sample of fermentation broth containing polysialic acid and endotoxin comprising the sequential steps: (i) adding to the sample a base having a pKa of at least 12 to form a basic solution having a pH of at least 12, incubating the solution for a pre-determined time at a pre-determined temperature; and (ii) recovery of PSA, suitably by (iii) passing the sample through an anion-exchange column whereby polysialic acid is absorbed on the ion exchange resin; (iv) washing the column with one washing buffer, whereby polysialic acid remains absorbed on the ion exchange resin; and (v) eluting the polysialic acid from the column using an elution buffer to provide a product solution of polysialic acid having reduced endotoxin content.
    • 本发明涉及降低含有唾液酸和内毒素的发酵肉汤样品的内毒素含量的方法,其包括以下顺序步骤:(i)向样品中加入pKa至少为12的碱,以形成具有 pH至少为12,在预定温度下将溶液温育预定时间; 和(ii)PSA的回收,适当地通过(iii)使样品通过阴离子交换柱,由此唾液酸被吸收在离子交换树脂上; (iv)用一个洗涤缓冲液洗涤该柱,由此聚唾液酸保持吸收在离子交换树脂上; 和(v)使用洗​​脱缓冲液从柱洗脱聚唾液酸以提供具有降低的内毒素含量的聚唾液酸的产物溶液。
    • 3. 发明授权
    • Hardware-based rate control for bursty traffic
    • 突发性流量的基于硬件的速率控制
    • US07652988B2
    • 2010-01-26
    • US10446419
    • 2003-05-28
    • Sanjay JainDeepak AatreshDaniel M. Hegglin
    • Sanjay JainDeepak AatreshDaniel M. Hegglin
    • H04L12/26
    • H04L47/10
    • A hardware-based rate control engine is designed to allow credits to be accumulated over multiple time-slices up to a maximum credit limit. The rate control engine is also allowed to dispatch packets up to a maximum drain rate during each time-slice as long as sufficient credits are available. Allowing credits to accumulate over multiple time slices allows unused bandwidth to be saved during times of little or no traffic and used when the subsequent traffic bursts arrive. Additionally, limiting the maximum drain rate puts a cap on how fast the saved bandwidth can be consumed by subsequent traffic bursts. The rate control settings can be adapted in response to a characteristic, or characteristics, of the traffic flow. For example, one group of settings of a traffic flow can be used for bursty traffic, while a different group of settings can be used for smooth traffic.
    • 基于硬件的速率控制引擎被设计为允许在多个时间片上积累信用以达到最大信用限额。 只要有足够的信用额度,速率控制引擎也可以在每个时间片段内调度数据包,达到最大排放速率。 允许信用累积多个时间片允许在很少或没有流量的时间内保存未使用的带宽,并且在随后的业务突发到达时使用。 另外,限制最大漏极率可以说明随后的业务脉冲串可以节省多长时间的带宽。 速率控制设置可以响应于业务流的特性或特性进行调整。 例如,流量的一组设置可以用于突发流量,而不同的设置组可用于平滑流量。
    • 9. 发明授权
    • Method and apparatus for reduced latency in hold bus cycles
    • 在保持总线周期中减少延迟的方法和装置
    • US5398244A
    • 1995-03-14
    • US92488
    • 1993-07-16
    • Gregory S. MathewsDeepak J. AatreshSanjay Jain
    • Gregory S. MathewsDeepak J. AatreshSanjay Jain
    • G06F13/30G06F13/364H04J3/00
    • G06F13/364G06F13/30
    • An innovative protocol and system for implementing the same enables quick release of the bus by the master device, such as a CPU, to permit slave devices access to the bus. In one embodiment, the arbiter can select between the original hold protocol and quick hold protocol according to predetermined criteria which indicates that a low latency response is requested. Upon assertion of a QHOLD signal, the CPU issues a burst last signal to prematurely terminate outstanding burst transactions on the bus in a manner transparent to the slave devices. Once the outstanding bus cycles are complete, the CPU performs an internal backoff to immediately release the bus for access by the slave device requesting access. Any pending burst cycles which were terminated prematurely by the QHOLD signal, are subsequently restarted for the data not transacted by the CPU after the slave device completes access to the bus. The internal backoff mechanism is similarly transparent to the slave devices and does not cause a backoff signal to be issued to the peripherals or devices coupled to the bus. Thus, the addition of a quick hold protocol is added without significant modification of the slave devices' bus interface.
    • 用于实现该协议和系统的创新协议和系统能够通过主设备(例如CPU)快速释放总线,以允许从设备访问总线。 在一个实施例中,仲裁器可以根据预定标准在原始保持协议和快速保持协议之间进行选择,这些标准指示请求低延迟响应。 在断言QHOLD信号时,CPU以对从属设备透明的方式发出突发上一个信号以提前终止总线上的突发事件。 一旦未完成的总线周期完成,CPU将执行内部退避,以立即释放总线以供从机设备请求访问。 随后,在从站设备完成对总线的访问之后,由QHOLD信号提前终止的任何未决突发周期随后重新启动,以便CPU不处理数据。 内部退避机制对于从属设备类似地是透明的,并且不会导致向连接到总线的外围设备或设备发出退避信号。 因此,添加快速保持协议,而不显着修改从设备的总线接口。