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1. 发明授权

US06328710B1 Process improvements for preparing catheter balloons 失效
标题翻译：制备导管球囊的工艺改进
公开(公告)号：US06328710B1
公开(公告)日：2001-12-11
申请号：US08955984
申请日：1997-10-22
申请人： Lixiao Wang , Paul J. Miller , Daniel J. Horn , Deborah A. Frank
发明人： Lixiao Wang , Paul J. Miller , Daniel J. Horn , Deborah A. Frank
IPC分类号： A61M2900
CPC分类号： A61M25/1029 , A61M25/0045 , A61M25/1002 , A61M25/104 , A61M2025/1075 , A61M2025/1088 , B29C35/041 , B29C49/04 , B29C49/18 , B29C49/783 , B29C2049/0089 , B29K2067/00 , B29K2105/258 , B29K2905/12 , B29L2031/7542 , Y10T428/1331 , Y10T428/1352 , Y10T428/139
摘要： A method for forming a balloon for a dilatation catheter may utilize the steps of extruding a tubing preform of a polyester resin and then blowing the tubing into an oriented balloon, wherein the tubing preform is dried prior to blowing into the balloon form. Other process steps by which balloon cone and waist thicknesses may be reduced involve varying the axial tension and blowing pressure at several stages as a mold containing the balloon preform is dipped into a heating medium. Specifically, tubing of a thermoplastic material is placed in a mold and blown by pressurizing and tensioning the tubing and gradually dipping the mold into a heated heat transfer media so as to sequentially blow a first waist, a body and a second waist portion. The tubing is subjected to a relatively lower pressure while the body portion is blown than while the first and second waist portions are blown.
摘要翻译：用于形成用于扩张导管的球囊的方法可以采用以下步骤：挤出聚酯树脂的管坯预成型件，然后将管道吹入定向气囊中，其中将管坯预先吹入气囊形式之前进行干燥。球囊和腰部厚度可能减小的其他工艺步骤包括在将包含球囊预制件的模具浸入加热介质中时，在几个阶段改变轴向张力和吹塑压力。具体地说，将热塑性材料的管材放置在模具中，并通过加压和张紧管子并将模具逐渐浸入加热的传热介质中，以便顺序地吹动第一腰部，身体和第二腰部部分而吹塑。当吹塑本体部分时，管道相对于第一和第二腰部部分被吹送而受到相对较低的压力。

2. 发明申请

US20120150109A1 MEDICAL DEVICES COMPRISING NANOCOMPOSITES 审中-公开
标题翻译：包含纳米复合体的医疗器械
公开(公告)号：US20120150109A1
公开(公告)日：2012-06-14
申请号：US13402141
申请日：2012-02-22
申请人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, JR. , Jan Weber
发明人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, JR. , Jan Weber
IPC分类号： A61M25/10
CPC分类号： A61F2/95 , A61F2/01 , A61F2/02 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61L29/126 , A61L31/125 , Y10S623/90 , Y10S977/905
摘要： The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.
摘要翻译：本发明提供包含纳米复合材料的医疗装置。通过在其生产中利用纳米复合材料，本发明的医疗装置可以以各种有利的性质生产。还提供了制造本发明的医疗装置的方法。由于本发明的装置预期在使用中提供某些优点，还提供了包括治疗或诊断方法的医疗护理方法，其中本发明的装置与被治疗或被诊断的身体进行治疗接触。

3. 发明申请

US20100010440A1 Medical Devices Comprising Nanocomposites 有权
标题翻译：包含纳米复合材料的医疗器械
公开(公告)号：US20100010440A1
公开(公告)日：2010-01-14
申请号：US12563780
申请日：2009-09-21
申请人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, JR. , Jan Weber
发明人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, JR. , Jan Weber
IPC分类号： A61M25/10
CPC分类号： A61F2/95 , A61F2/01 , A61F2/02 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61L29/126 , A61L31/125 , Y10S623/90 , Y10S977/905
摘要： The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.
摘要翻译：本发明提供包含纳米复合材料的医疗装置。通过在其生产中利用纳米复合材料，本发明的医疗装置可以以各种有利的性质生产。还提供了制造本发明的医疗装置的方法。由于本发明的装置预期在其使用中提供某些优点，还提供了包括治疗或诊断方法的医疗护理方法，其中本发明的装置与被治疗或被诊断的身体进行治疗接触。

4. 发明授权

US07591831B2 Medical devices comprising nanocomposites 有权
标题翻译：包含纳米复合材料的医疗器械
公开(公告)号：US07591831B2
公开(公告)日：2009-09-22
申请号：US10259545
申请日：2002-09-27
申请人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, Jr. , Jan Weber
发明人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, Jr. , Jan Weber
IPC分类号： A61M25/00 , A61M25/10 , A61F2/01 , A61F2/82
CPC分类号： A61F2/95 , A61F2/01 , A61F2/02 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61L29/126 , A61L31/125 , Y10S623/90 , Y10S977/905
摘要： The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provide a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.
摘要翻译：本发明提供包含纳米复合材料的医疗装置。通过在其生产中利用纳米复合材料，本发明的医疗装置可以以各种有利的性质生产。还提供了制造本发明的医疗装置的方法。由于本发明的装置预期在其使用中提供某些优点，还提供包括治疗或诊断方法的医疗护理方法，其中本发明的装置与被治疗或被诊断的身体进行治疗接触。

5. 发明授权

US09463103B2 Medical devices comprising nanocomposites 有权
标题翻译：包含纳米复合材料的医疗器械
公开(公告)号：US09463103B2
公开(公告)日：2016-10-11
申请号：US13402141
申请日：2012-02-22
申请人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, Jr. , Jan Weber
发明人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, Jr. , Jan Weber
IPC分类号： A61L29/00 , A61F2/95 , A61F2/01 , A61F2/02 , A61F2/958 , A61L29/12 , A61L31/12
CPC分类号： A61F2/95 , A61F2/01 , A61F2/02 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61L29/126 , A61L31/125 , Y10S623/90 , Y10S977/905
摘要： The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.
摘要翻译：本发明提供包含纳米复合材料的医疗装置。通过在其生产中利用纳米复合材料，本发明的医疗装置可以以各种有利的性质生产。还提供了制造本发明的医疗装置的方法。由于本发明的装置预期在使用中提供某些优点，还提供了包括治疗或诊断方法的医疗护理方法，其中本发明的装置与被治疗或被诊断的身体进行治疗接触。

6. 发明授权

US08133250B2 Medical devices comprising nanocomposites 有权
标题翻译：包含纳米复合材料的医疗器械
公开(公告)号：US08133250B2
公开(公告)日：2012-03-13
申请号：US12563780
申请日：2009-09-21
申请人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, Jr. , Jan Weber
发明人： Edward Parsonage , Daniel J. Horn , John J. Chen , Paul J. Miller , Douglas A. Devens, Jr. , Jan Weber
IPC分类号： A61M25/00 , A61M25/10
CPC分类号： A61F2/95 , A61F2/01 , A61F2/02 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61L29/126 , A61L31/125 , Y10S623/90 , Y10S977/905
摘要： The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.
摘要翻译：本发明提供包含纳米复合材料的医疗装置。通过在其生产中利用纳米复合材料，本发明的医疗装置可以以各种有利的性质生产。还提供了制造本发明的医疗装置的方法。由于本发明的装置预期在使用中提供某些优点，还提供了包括治疗或诊断方法的医疗护理方法，其中本发明的装置与被治疗或被诊断的身体进行治疗接触。

7. 发明申请

US20080177126A1 Radiopharmaceutical administration methods, fluid delivery systems and components thereof 有权
标题翻译：放射性药物给药方法，流体输送系统及其组分
公开(公告)号：US20080177126A1
公开(公告)日：2008-07-24
申请号：US11981429
申请日：2007-10-31
申请人： Leon J. Tate , James H. Shigeno , Steven C. Rygg , Jared E. Neff , Scott R. Griffith , Joseph E. Bisegna , Edward Ilgenfritz , Paul J. Miller , Scott Yanke
发明人： Leon J. Tate , James H. Shigeno , Steven C. Rygg , Jared E. Neff , Scott R. Griffith , Joseph E. Bisegna , Edward Ilgenfritz , Paul J. Miller , Scott Yanke
IPC分类号： A61M36/08
CPC分类号： A61M5/172 , A61K51/00 , A61M5/007 , A61M5/14 , A61M5/16822 , A61M5/3146 , A61M2005/1402 , G06F19/3468 , G16H20/17
摘要： A fluid path set for a fluid delivery system includes a tube coil that is designed to optimally position one or more volumes of a pharmaceutical within an ionization chamber to optimally measure and prepare a pharmaceutical dose for administration to a patient. The tube coil may be maintained in a desired dimensional geometry by means of a core structure around which the tube coil is positioned. Novel developments in radiopharmaceutical administration methods and systems include, but are not limited to, the configuration and layout of a fluid path set for use in a fluid delivery system, arrangements for piercing and drawing fluid from a pharmaceutical container (such as a vial), arrangements for optimizing the positioning of a tube coil within an ionization chamber, a handling system for transporting vial shields that maintain an operator's hand and fingers at a safe distance from a pharmaceutical vial, a method for calibrating a radiopharmaceutical delivery system in which the difference between the expected and measured activities of two radioisotopes are used to calculate an estimated error in the measured activity of a third radioisotope and a vial access system that ensures an optimal draw of fluid from a radiopharmaceutical container.
摘要翻译：设置用于流体输送系统的流体路径包括管线圈，其设计成在电离室内优化地定位药物的一个或多个体积，以最佳地测量并制备用于给予患者的药物剂量。管线圈可以通过围绕管线圈定位的芯结构保持在期望的尺寸几何形状。放射性药物管理方法和系统的新发展包括但不限于用于流体输送系统的流体路径组的配置和布局，用于从药物容器（例如小瓶）刺穿和抽取流体的布置，用于优化电离室内的管线圈的定位的布置，用于运输维护操作者的手和手指与药物瓶的安全距离的小瓶护罩的处理系统，用于校准放射性药物递送系统的方法，其中，使用两个放射性同位素的预期和测量的活动来计算第三放射性同位素和小瓶进入系统的测量活动的估计误差，其确保从放射性药物容器中最佳地吸取流体。

8. 发明授权

US5686697A Electrical circuit suspension system 失效
标题翻译：电路悬挂系统
公开(公告)号：US5686697A
公开(公告)日：1997-11-11
申请号：US369377
申请日：1995-01-06
申请人： Paul J. Miller , Kevin G. Foreman
发明人： Paul J. Miller , Kevin G. Foreman
IPC分类号： H01L25/16 , H05K1/00 , H05K1/18 , H05K3/28 , H01L23/28 , H01R23/68 , H05K7/02
CPC分类号： H01L25/165 , H05K3/284 , H01L2224/45144 , H01L2224/45147 , H01L2924/00014 , H01L2924/01015 , H01L2924/01047 , H05K1/0393 , H05K1/18
摘要： A device and method wherein electrical components are mechanically suspended and electrically interconnected in an insulative elastomeric body, such as silicone, thereby eliminating the need for a circuit board or other circuit substrate. The device can change shape through compression, distension, flexure, and other external forces while maintaining its electrical performance and mechanical integrity. The device can be compressed and deformed to fit snugly within another device, such as the shell of an electrical connector or a plastic clamshell, simultaneously creating spring forces for reliable electrical contacts and an environmental seal. Accordingly, the device and method can be used for a wide variety of purposes such as electrical filtering for avionics, computer or automotive connectors, or a non-intrusive manner to package electronics for medical implants.
摘要翻译：一种装置和方法，其中电气部件在诸如硅树脂的绝缘弹性体中机械地悬挂并电互连，从而不需要电路板或其它电路基板。该装置可以通过压缩，膨胀，弯曲和其他外力来改变形状，同时保持其电性能和机械完整性。该装置可以被压缩和变形以适应于另一装置，例如电连接器的外壳或塑料蛤壳，同时产生用于可靠的电接触和环境密封的弹簧力。因此，该装置和方法可以用于各种各样的目的，例如用于航空电子设备的电气过滤，计算机或汽车连接器，或非侵入式的方式来封装用于医疗植入物的电子装置。

9. 发明授权

US08105274B2 Catheter incorporating a high column strength distal tip region 有权
标题翻译：导管结合高柱强度的远端尖端区域
公开(公告)号：US08105274B2
公开(公告)日：2012-01-31
申请号：US12848673
申请日：2010-08-02
申请人： Paul J. Miller , Tracee E. J. Eidenschink
发明人： Paul J. Miller , Tracee E. J. Eidenschink
IPC分类号： A61M29/00
CPC分类号： A61M25/0074 , A61M25/0023 , A61M25/008 , A61M25/104 , A61M2025/1093
摘要： A catheter is disclosed providing a balloon catheter having a distal tip that is flexible while additionally incorporating high column strength. The present invention additionally provides a distal tip region that accommodates for various sized guidewires. In preferred embodiments, the distal tip region is initially configured for accommodating the passage of 0.12-inch guidewires only. Through specific manufacturing processes, however, the distal tip is modified so that it also may be expanded to accommodate the passage of 0.14-inch guidewires. In additional preferred embodiments, an elastomeric sleeve is disposed over the modified distal tip to allow the tip to return to the initial 0.12 -inch accommodating profile when the larger 0.14-inch guidewire is withdrawn from the catheter.
摘要翻译：公开了一种导管，其提供具有柔性的远侧末端的气囊导管，同时还具有高柱强度。本发明另外提供一种可容纳各种大小的导丝的远侧尖端区域。在优选实施例中，远端尖端区域最初被构造成仅容纳0.12英寸导线的通道。然而，通过特定的制造过程，远侧末端被修改，使得其也可以被扩张以适应0.14英寸导丝的通过。在另外的优选实施例中，当更大的0.14英寸导丝从导管中取出时，弹性体套筒设置在修改的远侧末端上方，以允许尖端返回到初始的0.12英寸容纳轮廓。

10. 发明授权

US07879008B2 Control device for a fluid delivery system 有权
标题翻译：流体输送系统的控制装置
公开(公告)号：US07879008B2
公开(公告)日：2011-02-01
申请号：US11085616
申请日：2005-03-21
申请人： John A. Haury , James M. Gimbel , Matthew J. Leroch, IV , Paul J. Miller , Gerald W. Callan , Richard C. Morton , Ralph E. Kopacko , Jennie Kwo , Luis A. Padraza , Roderick H. Beaulieu , Russell W. Wade , Milan V. Trcka , Mark Evan Whitebook
发明人： John A. Haury , James M. Gimbel , Matthew J. Leroch, IV , Paul J. Miller , Gerald W. Callan , Richard C. Morton , Ralph E. Kopacko , Jennie Kwo , Luis A. Padraza , Roderick H. Beaulieu , Russell W. Wade , Milan V. Trcka , Mark Evan Whitebook
IPC分类号： A61M1/00
CPC分类号： A61M5/16877 , A61M5/007 , A61M5/16804 , A61M2205/3576
摘要： The control device is used to control delivery of fluid from a fluid delivery system during a medical injection procedure. The fluid delivery system includes an injector adapted to actuate a syringe used to deliver the injection fluid to a patient. The control device is operatively associated with the injector for controlling discrete flow rates of injection fluid delivered to the patient. The control device includes a housing and an actuator associated with the housing. An electronic substrate is disposed within the housing and comprises a conductive pattern. The actuator is adapted for operative association with the conductive pattern. The conductive pattern includes a plurality of predetermined digital values corresponding to discrete flow rates of injection fluid to be delivered by the injector, such that when the actuator is actuated the actuator operatively associates with the conductive pattern for transmitting the digital values to the injector.
摘要翻译：控制装置用于在医疗注射过程期间控制来自流体输送系统的流体的输送。流体递送系统包括适于致动用于将注射流体输送给患者的注射器的注射器。控制装置可操作地与注射器相关联，用于控制输送给患者的注射液体的离散流速。控制装置包括壳体和与壳体相关联的致动器。电子基板设置在壳体内并且包括导电图案。致动器适于与导电图案操作地关联。导电图案包括对应于由喷射器输送的喷射流体的离散流速的多个预定数字值，使得当致动器被致动时，致动器可操作地与导电图案相关联，以将数字值传送到喷射器。

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