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1. 发明申请

US20110124948A1 RADIOLABELED TREATMENT INFUSION SYSTEM, APPARATUS, AND METHODS OF USING THE SAME 审中-公开
标题翻译：放射线治疗输注系统，装置及其使用方法
公开(公告)号：US20110124948A1
公开(公告)日：2011-05-26
申请号：US12936083
申请日：2009-04-03
申请人： Daniel L. Yokell
发明人： Daniel L. Yokell
IPC分类号： A61M36/08
CPC分类号： A61M5/1407 , A61M5/007 , A61M5/1415 , A61M5/1785 , A61M2209/08 , G21F5/015 , G21G1/0005 , G21H5/02
摘要： Described herein are methods and devices for infusion of a radioactive compound, such as yttrium-90 radiolabeled somatostatin peptide or analog. A radiation shield defining a shielded cavity suitable for storing a radioactive substance includes a first aperture providing external access to the shielded cavity and a second aperture suitable for transferring a dosage vial into and out of the shielded cavity. A removable shielded plug and panel are adapted to shield respective apertures of the radiation shield. At least one dose of a radiolabeled compound stored in a vial in the radiation shield is delivered through a fluid communication channel at a rate of about 500 mL/hour. The fluid communication channel is washed after delivery, such that the process substantially reduces radiation exposure during infusion of the radiolabeled compound into a patient.
摘要翻译：本文描述了用于输注放射性化合物的方法和装置，例如钇-90放射性标记的生长抑素肽或类似物。限定适于存储放射性物质的屏蔽空腔的辐射屏蔽包括提供对屏蔽空腔的外部通路的第一孔和适于将剂量小瓶转入和移出屏蔽腔的第二孔。可拆卸屏蔽插头和面板适于屏蔽辐射屏蔽的各个孔。储存在辐射屏蔽中的小瓶中的至少一剂放射性标记化合物以约500mL /小时的速率通过流体连通通道输送。流体连通通道在输送后洗涤，使得该过程在将放射性标记的化合物输注入患者期间显着降低辐射暴露。

2. 发明申请

US20120041253A1 Protective Apparatus for Chemotherapy Injection Needle 审中-公开
标题翻译：化疗注射针保护装置
公开(公告)号：US20120041253A1
公开(公告)日：2012-02-16
申请号：US12853432
申请日：2010-08-10
申请人： Ching-Yang Wu , Yun-Hen Liu , Po-Jen Ko
发明人： Ching-Yang Wu , Yun-Hen Liu , Po-Jen Ko
IPC分类号： A61M36/08
CPC分类号： A61M5/321 , A61M5/1418 , A61M5/158 , A61M5/3216 , A61M2005/1416 , A61M2005/1581
摘要： A protective apparatus for a chemotherapy injection needle, includes a coring needle, a plastic film integrated with a hand-held film, and an injection vessel, wherein the coring needle is a through, hollow and metal needle having a needle head bent downwards to form an angle with a needle body which connects to the injection vessel at a rear end. The plastic film has two trapezoidal and protruding wings extending to two sides, and when the two protruding wings are folded to clamp the needle head, the protruding wings' extending length is sufficient to wrap a tip part of the needle head, and positions where the protruding wings wrap the tip part are corresponding to concaved grooves of the needle head, so that the two protruding wings attach closely with each other. Also, the two protruding wings engage with each other by a locking device to secure the protruding wings.
摘要翻译：一种用于化疗注射针的保护装置，包括取芯针，与手持膜一体化的塑料膜和注射容器，其中所述取芯针是具有向下弯曲以形成的针头的通孔，中空和金属针与后端的与注射容器连接的针体的角度。塑料薄膜具有两个延伸到两侧的梯形和突出的翼，当两个突出的翼折叠以夹住针头时，突出的翼的延伸长度足以包裹针头的尖端部分，尖头部分的突出翼片对应于针头的凹槽，使得两个突出的翼片彼此紧密地附接。此外，两个突出的翼通过锁定装置彼此接合以固定突出的翼。

3. 发明授权

US4941874A Device for the administration of implants 失效
标题翻译：植入物管理装置
公开(公告)号：US4941874A
公开(公告)日：1990-07-17
申请号：US229957
申请日：1988-08-09
申请人： Jurgen K. Sandow , Wilfried De Felice , Horst Pajunk , Heinrich Pajunk
发明人： Jurgen K. Sandow , Wilfried De Felice , Horst Pajunk , Heinrich Pajunk
IPC分类号： A61M37/00 , A61B17/00 , A61M20060101 , A61M5/00 , A61M31/00 , A61M36/00 , A61M36/08 , A61M36/12
CPC分类号： A61M37/0069
摘要： The invention relates to a device for the injection of implants, preferably implants "in the form of small rods" (called rods), which are used for the long-term treatment of diseases, whose essential features are the completely transparent construction, especially of the injector body (3), as well as a protecting device which prevents the plunger rod from falling out, and a protective cap (6) for the plunger rod.
摘要翻译：本发明涉及一种用于注射植入物的装置，优选地以“小杆”形式（称为棒）的植入物，其用于长期治疗疾病，其基本特征是完全透明的构造，特别是喷射器主体（3）以及防止柱塞杆脱落的保护装置和用于柱塞杆的保护盖（6）。

4. 发明授权

US4715359A Safety bottle and cap for the administration of liquid radioactive iodine 失效
标题翻译：用于管理液体放射性碘的安全瓶和盖
公开(公告)号：US4715359A
公开(公告)日：1987-12-29
申请号：US845259
申请日：1986-03-28
申请人： U. Yun Ryo
发明人： U. Yun Ryo
IPC分类号： A61J7/00 , A61M36/08 , A61N5/12
CPC分类号： A61J7/0038 , A61J7/0046
摘要： A safety cap for tightly closing a container having liquid radioactive iodine solution in it. The cap is provided with a pair of holes through which extend a pair of straws, each of the straws having an inner end in communication with the interior of the container. Each straw also has an outer end, one of which is insertable into the patient's mouth for drinking the liquid radioactive iodine solution in the container, and the other of which is insertable into a glass of water so that, after the patient has drunk most of the liquid radioactive iodine solution in the container, the residue of the solution in the bottle may be flushed out by forming a partial vacuum in the interior of the bottle, thereby causing the water in the glass to be drawn into the interior of the container to be mixed with the residue of the solution and, thereafter, to be drawn into the mouth and drunk by the patient. The dispenser, thus formed, prevents any accidental leakage of radioactivity from the liquid radioactive iodine solution to the ambient air and, therefore, to any person, such as a doctor or nurse, administering the dosage of liquid radioactive iodine solution. The safety cap also prevents accidental spilling of the liquid radioactive iodine solution during administration of the liquid to the patient, since access to the liquid in the container is provided by the straws, with the safety cap not removed from the bottle.
摘要翻译：一个安全帽，用于紧密关闭其中具有液体放射性碘溶液的容器。盖设置有一对孔，通过该孔延伸一对吸管，每个吸管具有与容器内部连通的内端。每个吸管还具有外端，其中一个可插入到患者口中，用于饮用容器中的液体放射性碘溶液，另一个可插入一杯水中，使得在患者醉了大部分容器中的液体放射性碘溶液可以通过在瓶子的内部形成部分真空而将瓶子中的溶液残留物冲洗掉，从而使玻璃中的水被吸入容器的内部，与溶液的残留物混合，然后被吸入口中并由患者饮用。如此形成的分配器防止放射性物质从液体放射性碘溶液泄漏到环境空气中，并因此防止任何人，例如医生或护士，给予液体放射性碘溶液的剂量。安全帽还可防止液体向患者投放期间意外泄漏液体放射性碘溶液，因为通过吸管提供容器中的液体，而安全帽不能从瓶中取出。

5. 发明申请

US20120310031A1 SHIELDING ASSEMBLIES FOR INFUSION SYSTEMS 审中-公开
标题翻译：用于输液系统的屏蔽组件
公开(公告)号：US20120310031A1
公开(公告)日：2012-12-06
申请号：US13588341
申请日：2012-08-17
申请人： Charles R. Quirico , Ernest Balestracci , Daniel Darst , Eric J. Krause , Vishal N. Lokhande , Jacob S. Childs , Peter B. Madson , Daniel V. Clements
发明人： Charles R. Quirico , Ernest Balestracci , Daniel Darst , Eric J. Krause , Vishal N. Lokhande , Jacob S. Childs , Peter B. Madson , Daniel V. Clements
IPC分类号： A61M36/08
CPC分类号： G21F3/00 , A61M5/007 , A61M5/14 , A61M5/1407 , A61M5/1785 , A61M2209/08 , G01T1/02 , Y10T29/49826
摘要： A shielding assembly for an infusion system includes a plurality of compartments and a door for each compartment, and provides a radioactive radiation barrier for the compartments. One of the compartments contains a radioisotope generator of the infusion system and another of the compartments may contain a waste bottle of the infusion system. An opening into each of the generator and waste bottle compartments may be oriented upward, and the opening into the latter may be at a higher elevation than the opening into the former, for example, to facilitate independent removal and replacement of each. A door of at least one of the compartments, other than the generator compartment, when closed, may prevent the door of the generator compartment from being opened. A cabinet structure for the infusion system may enclose the shielding assembly and secure the generator.
摘要翻译：用于输注系统的屏蔽组件包括多个隔室和用于每个隔室的门，并为隔间提供放射性辐射屏障。其中一个隔室含有输注系统的放射性同位素发生器，另一个隔室可以包含输液系统的废液瓶。每个发电机和废瓶隔间的开口可以向上定向，并且进入后者的开口可以处于比通向前者的开口更高的高度，例如以便于各自独立地移除和更换。除了发电机室之外，至少一个隔间的门在关闭时可能会阻止发电机室的门被打开。用于输注系统的橱柜结构可以封闭屏蔽组件并固定发电机。

6. 发明申请

US20090292157A1 Radiation Shielded Syringe Assembly and Uses Thereof 审中-公开
标题翻译：辐射屏蔽注射器组件及其用途
公开(公告)号：US20090292157A1
公开(公告)日：2009-11-26
申请号：US12374051
申请日：2007-07-12
申请人： John K. Bruce , Frank M Fago
发明人： John K. Bruce , Frank M Fago
IPC分类号： A61M36/08
CPC分类号： A61M5/1785 , A61M2005/312 , A61M2005/3128 , G21F5/018
摘要： The application relates to radiation shielding (12) for use with radiopharmaceutical syringes (14). For example, in at least some regards, the invention relates to a syringe radiation shield that includes a sleeve (18) having a syringe receptacle defined therein to accommodate a barrel (26) of the syringe. In addition, this syringe radiation shield may also include a cover (20) having a plunger receptacle defined therein to accommodate a plunger of the syringe. The sleeve and the cover may be removably coupled with one another so that the syringe can be housed within the syringe radiation shield, for example, during administration of a radiopharmaceutical from the syringe.
摘要翻译：本申请涉及用于放射性药物注射器（14）的辐射屏蔽（12）。例如，至少在某些方面，本发明涉及一种注射器辐射屏蔽，其包括具有限定在其中的注射器容器的套筒（18），以容纳注射器的筒体（26）。此外，该注射器辐射屏蔽还可以包括具有限定在其中的柱塞接收器以容纳注射器的柱塞的盖（20）。套筒和盖可以彼此可拆卸地联接，使得注射器可以容纳在注射器辐射屏蔽内，例如在从注射器施用放射性药物期间。

7. 发明授权

US07498595B2 Positron radioactive drug radiation shielding device 有权
标题翻译：正电子放射性药物辐射屏蔽装置
公开(公告)号：US07498595B2
公开(公告)日：2009-03-03
申请号：US11258015
申请日：2005-10-26
申请人： Chi-Kuang Chen
发明人： Chi-Kuang Chen
IPC分类号： G21F5/018 , A61M36/08
CPC分类号： G21F5/018 , G21Y2002/201 , G21Y2002/301 , G21Y2004/30
摘要： The present invention provides an improved positron radioactive drug radiation shielding device, which achieves savings in space required to store a canister after dismantling the device. Furthermore, a tungsten sleeve is disposed within the canister, and functions in coordination with a syringe. The tungsten sleeve is able to block radioactive radiation released by radioactive drugs contained in the syringe. Moreover, a front cover and a rear cover joined to two sides of the canister enable a hermetically-sealed space to be formed within the canister, which increases the effectiveness of blocking the amount of radiation from the canister, thereby reducing danger to the human body from the radiation.
摘要翻译：本发明提供一种改进的正电子放射性药物辐射屏蔽装置，其在拆卸装置之后实现储存罐所需的空间。此外，钨套筒设置在罐内，并且与注射器配合起作用。钨套筒能够阻挡注射器中放射性药物释放的放射性辐射。此外，连接到罐的两侧的前盖和后盖能够在罐内形成气密密封的空间，这增加了阻挡来自罐的辐射量的有效性，从而减少对人体的危害从辐射。

8. 发明申请

US20050224728A1 Packaging system for radioactive materials 有权
标题翻译：放射性物质包装系统
公开(公告)号：US20050224728A1
公开(公告)日：2005-10-13
申请号：US10966490
申请日：2004-10-15
申请人： Uwe Schwarz , Joachim Kahl
发明人： Uwe Schwarz , Joachim Kahl
IPC分类号： A61M36/08 , G21F5/018 , A61L15/00 , G21F5/00
CPC分类号： G21F5/018 , G21Y2002/304 , G21Y2002/501 , G21Y2004/303 , G21Y2004/304
摘要： Packaging system for radioactive materials having: a vial with closure for accommodating the radioactive material; a first casing to be opened, enclosing the vial, and essentially made from a transparent material, which has a capture cross-section selected for shielding at least a part of the emitted radiation; and a second casing to be opened, made from a material with a high capture cross-section (Z) for essentially shielding the remaining radiation, the second casing enclosing the first casing.
摘要翻译：用于放射性物质的包装系统，具有：具有用于容纳放射性物质的封闭物的小瓶; 要打开的第一套管，包围小瓶，并且基本由透明材料制成，其具有被选择用于屏蔽所发射的辐射的至少一部分的捕获截面; 以及由具有高捕获截面（Z）的材料制成的用于基本上屏蔽剩余辐射的待打开的第二壳体，所述第二壳体包围所述第一壳体。

9. 发明授权

US10016618B2 Methods and systems for integrated radiopharmaceutical generation, preparation, transportation and administration 有权
公开(公告)号：US10016618B2
公开(公告)日：2018-07-10
申请号：US15142000
申请日：2016-04-29
申请人： BAYER HEALTHCARE LLC
发明人： Alan D. Hirschman , Arthur E. Uber, III , David M. Reilly , John F. Kalafut , Frederick W. Trombley, III , Steven J. Remis , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths , Marc A. Mabie , Mark Trocki
IPC分类号： A61B6/00 , A61M36/06 , A61M36/08 , A61N5/10 , A61B6/03 , A61B6/04 , A61M5/172 , G06F19/00 , G21G4/08 , A61B6/10 , A61B5/055 , G21F5/015 , A61B5/0205 , A61B5/00 , A61M5/00 , A61M5/145 , A61M5/168 , A61M5/178
CPC分类号： A61N5/1001 , A61B5/0205 , A61B5/055 , A61B5/7289 , A61B6/032 , A61B6/037 , A61B6/0478 , A61B6/107 , A61B6/4057 , A61B6/4258 , A61B6/4423 , A61B6/507 , A61B6/508 , A61B6/5288 , A61B6/548 , A61M5/007 , A61M5/14546 , A61M5/1456 , A61M5/16827 , A61M5/16881 , A61M5/1723 , A61M5/1785 , A61M2205/3576 , A61N5/1071 , A61N2005/1021 , A61N2005/1094 , G06F19/3468 , G16H20/17 , G21F5/015 , G21G4/08
摘要： An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

10. 发明申请

US20110028775A1 THERAPEUTIC INFUSION AND TRANSFER SYSTEM FOR USE WITH RADIOACTIVE AGENTS 审中-公开
标题翻译：用于放射性药物的治疗输入和转移系统
公开(公告)号：US20110028775A1
公开(公告)日：2011-02-03
申请号：US12678670
申请日：2008-09-15
申请人： Norman Lafrance , Miguel De La Guardia
发明人： Norman Lafrance , Miguel De La Guardia
IPC分类号： A61M36/08
CPC分类号： A61M5/142 , A61M2205/75
摘要： Described herein are infusion systems and methods for delivering a radiopharmaceutical agent to a subject without exposing an administering health care professional to a potentially deleterious amount of radiation.
摘要翻译：本文描述的输注系统和方法用于将放射性药剂递送到受试者，而不会使管理卫生保健专业人员暴露于潜在有害量的辐射。

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