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1. 发明申请

US20070096014A1 CONFOCAL SCANNER 失效
标题翻译：协同扫描仪
公开(公告)号：US20070096014A1
公开(公告)日：2007-05-03
申请号：US11382724
申请日：2006-05-11
申请人： Kenta Mikuriya , Takashi Yoshida , Yasuhito Kosugi
发明人： Kenta Mikuriya , Takashi Yoshida , Yasuhito Kosugi
IPC分类号： H01J3/14
CPC分类号： G02B21/0044 , G02B21/0032 , G02B27/30
摘要： There is achieved a confocal scanner capable of being adjusted can be achieved with ease so as to be in a well-balanced state where a utilization ratio of an excited light is high and light quantity distribution on the cross-section of beams is excellent in evenness even in the case of being coupled with an optical fiber varying in a beam spread-angle. The confocal scanner is provided with a collimator lens for causing beams outgoing from an emission end of an optical fiber for guiding an excited light, with a predetermined spread-angle, to be converted into collimated beams before falling on a microlens disk, wherein a beam spread-angle adjusting means for adjusting the spread-angle is provided between the emission end, and the collimator lens.
摘要翻译：实现能够被调整的共焦扫描器能够容易地实现，以便处于激发光的利用率高的良好平衡状态，并且横梁的横截面上的光量分布具有优异的均匀性即使在与光束扩展角度变化的光纤耦合的情况下也是如此。共焦扫描器设置有准直透镜，用于使得从光纤的发射端射出的光束以预定的扩展角度引导激发的光，在被落入微透镜盘之前被转换为准直的光束，其中光束在发射端和准直透镜之间设置用于调整扩展角的扩展角度调节装置。

2. 发明授权

US07592582B2 Confocal scanner having beam spread angle adjustment device 失效
标题翻译：共焦扫描器具有光束扩展角度调节装置
公开(公告)号：US07592582B2
公开(公告)日：2009-09-22
申请号：US11382724
申请日：2006-05-11
申请人： Kenta Mikuriya , Takashi Yoshida , Yasuhito Kosugi
发明人： Kenta Mikuriya , Takashi Yoshida , Yasuhito Kosugi
IPC分类号： H01J3/14 , G02B21/06
CPC分类号： G02B21/0044 , G02B21/0032 , G02B27/30
摘要： There is achieved a confocal scanner capable of being adjusted can be achieved with ease so as to be in a well-balanced state where a utilization ratio of an excited light is high and light quantity distribution on the cross-section of beams is excellent in evenness even in the case of being coupled with an optical fiber varying in a beam spread-angle. The confocal scanner is provided with a collimator lens for causing beams outgoing from an emission end of an optical fiber for guiding an excited light, with a predetermined spread-angle, to be converted into collimated beams before falling on a microlens disk, wherein a beam spread-angle adjusting means for adjusting the spread-angle is provided between the emission end, and the collimator lens.
摘要翻译：实现能够被调整的共焦扫描器能够容易地实现，以便处于激发光的利用率高的良好平衡状态，并且横梁的横截面上的光量分布具有优异的均匀性即使在与光束扩展角度变化的光纤耦合的情况下也是如此。共焦扫描器设置有准直透镜，用于使得从光纤的发射端射出的光束以预定的扩展角度引导激发的光，在被落入微透镜盘之前被转换为准直的光束，其中光束在发射端和准直透镜之间设置用于调整扩展角的扩展角度调节装置。

3. 发明申请

US20060072191A1 Confocal microscope 审中-公开
标题翻译：共焦显微镜
公开(公告)号：US20060072191A1
公开(公告)日：2006-04-06
申请号：US11242871
申请日：2005-10-05
申请人： Takashi Akiyama , Kenta Mikuriya , Yasuhito Kosugi
发明人： Takashi Akiyama , Kenta Mikuriya , Yasuhito Kosugi
IPC分类号： G02B21/06
CPC分类号： G02B21/0032 , G02B21/0044 , G02B21/0048 , G02B21/0084
摘要： In A confocal microscope, a mirror reflects illumination light to focus on a focal point face of a sample through an object lens. The mirror is rotated to scan a focal point of the illumination light. A confocal image provided based on returned light from the sample. The confocal microscope has a first multipinhole array which has a plurality of pinholes, and to which light emitted from a light source is illuminated, and a second multipinhole array which has a plurality of pinholes, and intercepts light from other than the focal point face out of the returned light from the sample. The first multipinhole array functions as a plurality of point light sources, and the illumination light is light which passes through the pinholes of the first multipinhole array.
摘要翻译：在共聚焦显微镜中，镜子反射照明光以通过物镜聚焦在样品的焦点面上。旋转镜子以扫描照明光的焦点。基于来自样品的返回光提供的共焦图像。共焦显微镜具有第一多孔阵列，其具有多个针孔，并且从光源发射的光被照射到该第一多孔阵列，以及第二多孔阵列，其具有多个针孔，并且将来自焦点以外的光截取为面向外来自样品的返回光。第一多孔阵列用作多个点光源，并且照明光是穿过第一多孔阵列的针孔的光。

4. 发明授权

US07190514B2 Confocal scanning microscope 有权
标题翻译：共焦扫描显微镜
公开(公告)号：US07190514B2
公开(公告)日：2007-03-13
申请号：US10916425
申请日：2004-08-12
申请人： Kenta Mikuriya , Yasuhiro Tanibata , Hideomi Negishi , Naoki Seki , Yasuhito Kosugi
发明人： Kenta Mikuriya , Yasuhiro Tanibata , Hideomi Negishi , Naoki Seki , Yasuhito Kosugi
IPC分类号： G02B21/06 , G02B21/00
CPC分类号： G02B21/0024
摘要： The present invention provides a confocal scanning microscope whereby fluorescence observations can be made using a plurality of types of excitation light without the need for attaching and detaching a light source to and from the optical fiber. The confocal scanning microscope comprises: a light source unit for emitting excitation light that excites a sample; a scanner unit for scanning the sample with the excitation light; and an imaging camera for capturing an image of the sample by receiving fluorescent light emitted from the sample; the light source unit having a plurality of light sources for emitting laser light with different wavelengths and a multicore optical fiber cable for transmitting light from the plurality of light sources, one end of the multicore optical fiber cable being separated into a plurality of optical fibers, and light from each of the plurality of light sources being input to one end of each of the separate optical fibers.
摘要翻译：本发明提供一种共焦扫描显微镜，其中可以使用多种类型的激发光进行荧光观察，而不需要将光源连接到光纤和从光纤分离。共焦扫描显微镜包括：用于发射激发样品的激发光的光源单元; 用于用激发光扫描样品的扫描器单元; 以及成像摄像机，用于通过接收从样本发射的荧光来捕获样本的图像; 所述光源单元具有用于发射具有不同波长的激光的多个光源和用于透射来自所述多个光源的光的多芯光缆，所述多芯光缆的一端被分离成多根光纤，并且来自多个光源中的每一个的光被输入到每个分离的光纤的一端。

5. 发明申请

US20060033988A1 Confocal scanning microscope 有权
标题翻译：共焦扫描显微镜
公开(公告)号：US20060033988A1
公开(公告)日：2006-02-16
申请号：US10916425
申请日：2004-08-12
申请人： Kenta Mikuriya , Yasuhiro Tanibata , Hideomi Negishi , Naoki Seki , Yasuhito Kosugi
发明人： Kenta Mikuriya , Yasuhiro Tanibata , Hideomi Negishi , Naoki Seki , Yasuhito Kosugi
IPC分类号： G02B21/06
CPC分类号： G02B21/0024
摘要： The present invention provides a confocal scanning microscope whereby fluorescence observations can be made using a plurality of types of excitation light without the need for attaching and detaching a light source to and from the optical fiber. The confocal scanning microscope comprises: a light source unit for emitting excitation light that excites a sample; a scanner unit for scanning the sample with the excitation light; and an imaging camera for capturing an image of the sample by receiving fluorescent light emitted from the sample; the light source unit having a plurality of light sources for emitting laser light with different wavelengths and a multicore optical fiber cable for transmitting light from the plurality of light sources, one end of the multicore optical fiber cable being separated into a plurality of optical fibers, and light from each of the plurality of light sources being input to one end of each of the separate optical fibers.
摘要翻译：本发明提供一种共焦扫描显微镜，其中可以使用多种类型的激发光进行荧光观察，而不需要将光源连接到光纤和从光纤分离。共焦扫描显微镜包括：用于发射激发样品的激发光的光源单元; 用于用激发光扫描样品的扫描器单元; 以及成像摄像机，用于通过接收从样本发射的荧光来捕获样本的图像; 所述光源单元具有用于发射具有不同波长的激光的多个光源和用于透射来自所述多个光源的光的多芯光缆，所述多芯光缆的一端被分离成多根光纤，并且来自多个光源中的每一个的光被输入到每个分离的光纤的一端。

6. 发明授权

US07400446B2 Confocal microscope 失效
标题翻译：共焦显微镜
公开(公告)号：US07400446B2
公开(公告)日：2008-07-15
申请号：US11362228
申请日：2006-02-27
申请人： Kenta Mikuriya , Takashi Yoshida , Takayuki Kei
发明人： Kenta Mikuriya , Takashi Yoshida , Takayuki Kei
IPC分类号： G02B21/06
CPC分类号： G02B21/004 , G02B21/0044 , G02B21/0076
摘要： A confocal microscope uses fluorescent or reflected light obtained by irradiating a plurality of beam spots to a sample so as to observe the sample. The confocal microscope has a phase modulator element which modulates phase of laser light to form the beam spots, a liquid crystal element which forms a plurality of pinholes through which only the fluorescent or the reflected light is transmitted, and a control section which controls the phase modulator element and the liquid crystal element.
摘要翻译：共焦显微镜使用通过对样品照射多个束斑而获得的荧光或反射光，以观察样品。共聚焦显微镜具有调制激光相位以形成光束斑的相位调制元件，形成仅透过荧光或反射光的多个针孔的液晶元件和控制相位的控制部调制元件和液晶元件。

7. 发明申请

US20060209399A1 Confocal microscope 失效
标题翻译：共焦显微镜
公开(公告)号：US20060209399A1
公开(公告)日：2006-09-21
申请号：US11362228
申请日：2006-02-27
申请人： Kenta Mikuriya , Takashi Yoshida , Takayuki Kei
发明人： Kenta Mikuriya , Takashi Yoshida , Takayuki Kei
IPC分类号： G02B21/06
CPC分类号： G02B21/004 , G02B21/0044 , G02B21/0076
摘要： A confocal microscope uses fluorescent or reflected light obtained by irradiating a plurality of beam spots to a sample so as to observe the sample. The confocal microscope has a phase modulator element which modulates phase of laser light to form the beam spots, a liquid crystal element which forms a plurality of pinholes through which only the fluorescent or the reflected light is transmitted, and a control section which controls the phase modulator element and the liquid crystal element.
摘要翻译：共焦显微镜使用通过对样品照射多个束斑而获得的荧光或反射光，以观察样品。共聚焦显微镜具有调制激光相位以形成光束斑的相位调制元件，形成仅透过荧光或反射光的多个针孔的液晶元件和控制相位的控制部调制元件和液晶元件。

8. 发明申请

US20060050375A1 Confocal microscope 审中-公开
标题翻译：共焦显微镜
公开(公告)号：US20060050375A1
公开(公告)日：2006-03-09
申请号：US11210656
申请日：2005-08-25
申请人： Kenta Mikuriya , Takayuki Kei , Takashi Yoshida
发明人： Kenta Mikuriya , Takayuki Kei , Takashi Yoshida
IPC分类号： G02B21/06
CPC分类号： G02B21/0076 , G02B21/0044 , G02B21/0064
摘要： A confocal microscope for performing an observation of a sample using a confocal image, the confocal microscope comprises a microscope, a confocal scanner of a Nipkow disk type, and a laser beam output section which is connected to the microscope and outputs a first laser beam for applying photic stimulation on the sample.
摘要翻译：共焦显微镜用于使用共聚焦图像进行样品的观察，共聚焦显微镜包括显微镜，Nipkow盘型的共聚焦扫描仪和激光束输出部分，其连接到显微镜并输出第一激光束对样品施加光刺激。

9. 发明授权

US5428475A Confocal optical scanner 失效
标题翻译：共焦光学扫描仪
公开(公告)号：US5428475A
公开(公告)日：1995-06-27
申请号：US942156
申请日：1992-09-08
申请人： Takeo Tanaami , Kenta Mikuriya
发明人： Takeo Tanaami , Kenta Mikuriya
IPC分类号： G02B3/00 , G02B3/08 , G02B21/00 , G02B26/02
CPC分类号： G02B3/0056 , G02B21/0044 , G02B21/0064 , G02B3/08 , G02B3/0006
摘要： A confocal optical scanner which realizes optical scanning without nonuniformity of brightness at the inside and outside periperies of the pinhole disk by arraying the pinholes along spiral tracks at the same pitch; which allows adjustment of decentering to be readily performed by disposing pinholes so that stripes do not occur even when decentering is large; which allows more incident light to be collected at the pinholes through a plurality of collector elements by disposing the pinholes at focal points of the collector elements; which improves luminous utilization efficacy by reducing the illumination area of light by adopting the collector elements to focus outside of the aperture pupil; which prevents decrease of confocal resolution due to pinhole diameter by causing the light reflected from the sample to not enter a collector disk; and which reduces stray light from the pinhole disk by covering non-collector portions of the collector disk with a shading film.
摘要翻译：一种共焦光学扫描仪，通过以相同的间距沿着螺旋轨道排列针孔，实现光学扫描，而不会在针孔盘的内侧和外侧的亮度不均匀; 这允许通过布置针孔来容易地进行偏心调节，使得即使在偏心较大时也不会发生条纹; 这允许通过将针孔设置在集电器元件的焦点处，通过多个收集器元件在针孔处收集更多的入射光; 通过采集收集器元件聚焦在孔径光瞳外部，通过减小光的照明面积来提高发光效率; 通过使得从样品反射的光不进入集电盘，防止由于针孔直径引起的共聚焦分辨率降低; 并且通过用遮光膜覆盖收集盘的非集电器部分来减少来自针孔盘的杂散光。

10. 发明授权

US06982824B2 Three-dimensional confocal microscope system 失效
标题翻译：三维共焦显微镜系统
公开(公告)号：US06982824B2
公开(公告)日：2006-01-03
申请号：US10800754
申请日：2004-03-16
申请人： Takayuki Kei , Kenji Hachiya , Kenta Mikuriya
发明人： Takayuki Kei , Kenji Hachiya , Kenta Mikuriya
IPC分类号： G02B21/00
CPC分类号： G02B21/0024
摘要： The present invention is characterized in that it is possible to provide a three-dimensional confocal microscope system configured so that an objective lens can be scanned in the optical-axis direction using an actuator to obtain sliced confocal images of a sample, wherein the actuator is driven using a scanning waveform signal, which is triangular or step-like and has been corrected so that acceleration is kept virtually constant at discontinuous points of change in the scanning waveform signal, thereby consistently providing sliced confocal images of the sample.
摘要翻译：本发明的特征在于，可以提供一种三维共聚焦显微镜系统，其被配置为使得可以使用致动器在光轴方向上扫描物镜，以获得样品的切片共聚焦图像，其中致动器是使用三角形或阶梯状的扫描波形信号进行驱动，并且已被校正，使得加速度在扫描波形信号的不连续点处几乎保持不变，从而一致地提供样品的切片共聚焦图像。

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