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1. 发明申请

US20130029964A1 [5, 6] HETEROCYCLIC COMPOUND 审中-公开
标题翻译： [5,6]杂环化合物
公开(公告)号：US20130029964A1
公开(公告)日：2013-01-31
申请号：US13595608
申请日：2012-08-27
申请人： Kazumasa Aoki , Satoshi Matsui , Kenji Yoshikawa , Hiroki Shimizu , Junko Sasaki , Katsuyoshi Nakajima , Osamu Kanno , Kiyoshi Oizumi
发明人： Kazumasa Aoki , Satoshi Matsui , Kenji Yoshikawa , Hiroki Shimizu , Junko Sasaki , Katsuyoshi Nakajima , Osamu Kanno , Kiyoshi Oizumi
IPC分类号： A61K31/4184 , C07D471/04 , A61K31/437 , C07D235/14 , C07D401/10 , C07D413/10 , A61K31/5377 , C07D405/12 , C07D491/056 , A61K31/4188 , C07D403/10 , A61K31/496 , A61K31/506 , A61K31/454 , A61K31/4439 , A61P19/08 , A61P19/10 , C07D235/12
CPC分类号： C07D235/06 , A61K31/4184 , A61K31/4188 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D403/04 , C07D405/12 , C07D405/14 , C07D417/04 , C07D471/04 , C07D491/056
摘要： An object of the present invention is to provide a novel low molecular weight compound exhibiting an osteogenesis-promoting action. This object is achieved by a compound having the general formula (I) or a pharmacologically acceptable salt thereof. In the general formula (I), R1 and R2 represent hydrogen atoms, and the like; R3 represents a hydrogen atom, and the like; X, Y, and Z represent nitrogen atoms, and the like; A represents a phenylene group, and the like; n represents 1 or 2, and the like; and V and W represent oxygen atoms, and the like.
摘要翻译：本发明的目的是提供一种表现出成骨促进作用的新型低分子量化合物。该目的通过具有通式（I）的化合物或其药理学上可接受的盐来实现。在通式（I）中，R 1和R 2表示氢原子等; R3表示氢原子等; X，Y和Z表示氮原子等; A表示亚苯基等; n表示1或2，等等; V和W表示氧原子等。

2. 发明申请

US20110269746A1 CYCLIC COMPOUND HAVING HETERO ATOM 失效
标题翻译：具有异位原子的环状化合物
公开(公告)号：US20110269746A1
公开(公告)日：2011-11-03
申请号：US13182777
申请日：2011-07-14
申请人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Daigo Asano
发明人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Daigo Asano
IPC分类号： A61K31/55 , A61K31/5377 , A61K31/496 , A61K31/4375 , A61K31/4725 , A61P19/00 , C07D413/14 , C07D413/04 , C07D471/04 , A61P19/10 , C07D405/14 , C07D401/14 , A61K31/5513 , C07D401/04
CPC分类号： C07D217/22 , C07D217/24 , C07D401/04 , C07D401/12 , C07D405/14 , C07D413/04 , C07D413/12 , C07D417/12 , C07D471/04
摘要： Compounds exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof: wherein A is selected from among a 3- to 10-membered heterocyclyl group, B is selected from among an amino group, and X is selected from N and CH.
摘要翻译：表现出具有通式（I）的成骨促进作用的化合物或其药理学上可接受的盐：其中A选自3-至10-元杂环基，B选自氨基，X选自来自N和CH。

3. 发明授权

US08685981B2 Cyclic compound having hetero atom 失效
标题翻译：具有杂原子的环状化合物
公开(公告)号：US08685981B2
公开(公告)日：2014-04-01
申请号：US13182777
申请日：2011-07-14
申请人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Daigo Asano
发明人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Daigo Asano
IPC分类号： A61K31/497
CPC分类号： C07D217/22 , C07D217/24 , C07D401/04 , C07D401/12 , C07D405/14 , C07D413/04 , C07D413/12 , C07D417/12 , C07D471/04
摘要： Compounds exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof: wherein A is selected from among a 3- to 10-membered heterocyclyl group, B is selected from among an amino group, and X is selected from N and CH.
摘要翻译：表现出具有通式（I）的成骨促进作用的化合物或其药理学上可接受的盐：其中A选自3-至10-元杂环基，B选自氨基，X选自来自N和CH。

4. 发明授权

US08410273B2 Cyclic compound having substituted phenyl group 失效
标题翻译：具有取代苯基的环状化合物
公开(公告)号：US08410273B2
公开(公告)日：2013-04-02
申请号：US13253792
申请日：2011-10-05
申请人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Satoru Naito
发明人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Satoru Naito
IPC分类号： C07D471/02 , A61K31/47
CPC分类号： C07D217/14 , C07D217/16 , C07D401/04 , C07D401/10 , C07D405/12 , C07D417/04 , C07D471/04
摘要： Low molecular weight compound exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof:
摘要翻译：表现出具有通式（I）的成骨促进作用的低分子量化合物或其药理学上可接受的盐：

5. 发明申请

US20120040936A1 CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP 失效
标题翻译：具有取代的苯基的环化合物
公开(公告)号：US20120040936A1
公开(公告)日：2012-02-16
申请号：US13253792
申请日：2011-10-05
申请人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Satoru Naito
发明人： Osamu Kanno , Katsuyoshi Nakajima , Kazumasa Aoki , Ryoichi Tanaka , Shimpei Hirano , Kiyoshi Oizumi , Satoru Naito
IPC分类号： A61K31/675 , A61K31/496 , A61K31/4375 , A61K31/4725 , A61K31/472 , A61P19/08 , C07D401/12 , C07F9/06 , C07D471/04 , C07D401/10 , C07D217/04 , A61P19/10 , A61K31/5377 , C07D413/12
CPC分类号： C07D217/14 , C07D217/16 , C07D401/04 , C07D401/10 , C07D405/12 , C07D417/04 , C07D471/04
摘要： Low molecular weight compound exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof:
摘要翻译：表现出具有通式（I）的成骨促进作用的低分子量化合物或其药理学上可接受的盐：

6. 发明授权

US07581613B2 Seat belt device 有权
标题翻译：安全带装置
公开(公告)号：US07581613B2
公开(公告)日：2009-09-01
申请号：US11773678
申请日：2007-07-05
申请人： Shotaro Odate , Hiroshi Akaba , Yutaka Wakisaka , Tsutomu Terasaki , Osamu Kanno , Kenichi Saito
发明人： Shotaro Odate , Hiroshi Akaba , Yutaka Wakisaka , Tsutomu Terasaki , Osamu Kanno , Kenichi Saito
IPC分类号： B60R22/00
CPC分类号： B60R22/46 , B60R22/4628 , B60R22/4676 , B60R2022/4666 , B60R2022/468
摘要： The seat belt device includes a first unit, a second unit, seat belt webbing, a spindle, a first pretensioner, a second pretensioner, and a controller. The first unit determines a possible collision of an automobile in response to a manipulation of the automobile by a driver. The second unit detects the collision of the automobile. The first pretensioner has a motor to rotate in response to a signal indicative of the possible collision determined by the first unit. The second pretensioner is pyrotechnically driven to rotate in response to a signal indicative of the collision detected by the second unit. The controller is configured to cancel an operation of the first pretensioner after an activation of the second pretensioner. The first pretensioner includes a limiter for restricting the motor from transmitting a driving force to the spindle exceeding a predetermined threshold.
摘要翻译：安全带装置包括第一单元，第二单元，安全带安全带，主轴，第一预紧器，第二预紧器和控制器。第一单元响应于驾驶员对汽车的操纵来确定汽车的可能碰撞。第二单元检测汽车的碰撞。第一预紧器具有响应于指示由第一单元确定的可能碰撞的信号而旋转的电动机。第二预张紧器被烟火地驱动以响应于指示由第二单元检测到的碰撞的信号而旋转。控制器被配置为在激活第二预张紧器之后取消第一预紧器的操作。第一预张紧器包括限制器，用于限制电动机将超过预定阈值的驱动力传递到主轴。

7. 发明申请

US20080012282A1 SEAT BELT DEVICE 有权
标题翻译：座垫设备
公开(公告)号：US20080012282A1
公开(公告)日：2008-01-17
申请号：US11773678
申请日：2007-07-05
申请人： Shotaro Odate , Hiroshi Akaba , Yutaka Wakisaka , Tsutomu Terasaki , Osamu Kanno , Kenichi Saito
发明人： Shotaro Odate , Hiroshi Akaba , Yutaka Wakisaka , Tsutomu Terasaki , Osamu Kanno , Kenichi Saito
IPC分类号： B60R22/46
CPC分类号： B60R22/46 , B60R22/4628 , B60R22/4676 , B60R2022/4666 , B60R2022/468
摘要： The seat belt device includes a first unit, a second unit, seat belt webbing, a spindle, a first pretensioner, a second pretensioner, and a controller. The first unit determines a possible collision of an automobile in response to a manipulation of the automobile by a driver. The second unit detects the collision of the automobile. The first pretensioner has a motor to rotate in response to a signal indicative of the possible collision determined by the first unit. The second pretensioner is pyrotechnically driven to rotate in response to a signal indicative of the collision detected by the second unit. The controller is configured to cancel an operation of the first pretensioner after an activation of the second pretensioner. The first pretensioner includes a limiter for restricting the motor from transmitting a driving force to the spindle exceeding a predetermined threshold.
摘要翻译：安全带装置包括第一单元，第二单元，安全带安全带，主轴，第一预紧器，第二预紧器和控制器。第一单元响应于驾驶员对汽车的操纵来确定汽车的可能碰撞。第二单元检测汽车的碰撞。第一预紧器具有响应于指示由第一单元确定的可能碰撞的信号而旋转的电动机。第二预张紧器被烟火地驱动以响应于指示由第二单元检测到的碰撞的信号而旋转。控制器被配置为在激活第二预张紧器之后取消第一预紧器的操作。第一预张紧器包括限制器，用于限制电动机将超过预定阈值的驱动力传递到主轴。

8. 发明授权

US07001897B2 1-methylcarbapenem derivatives 失效
标题翻译： 1-甲基碳青霉烯衍生物
公开(公告)号：US07001897B2
公开(公告)日：2006-02-21
申请号：US10439198
申请日：2003-05-15
申请人： Yoshiyuki Kobayashi , Tsuyoshi Shinozuka , Osamu Kanno
发明人： Yoshiyuki Kobayashi , Tsuyoshi Shinozuka , Osamu Kanno
IPC分类号： C07D477/20 , A61K31/454 , A61K31/421 , A61K31/426 , A61P31/04
CPC分类号： C07D477/20
摘要： A 1-methylcarbapenem compound represented by the formula (I): having antibacterial activity, pharmacologically acceptable esters or salts thereof and pharmaceutical compositions (particularly antibacterial agents) containing them as an active ingredient are described. In addition, the invention includes the use of these compounds, ester derivatives or salts for the manufacture of pharmaceutical compositions, or a method for the prevention or treatment of diseases (particularly bacterial infections) by administering a pharmacologically effective amount of the compounds, ester derivatives or salts to warm-blooded animals (particularly human beings).
摘要翻译：由式（I）表示的1-甲基碳青霉烯化合物

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