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1. 发明申请

US20130029964A1 [5, 6] HETEROCYCLIC COMPOUND 审中-公开
标题翻译： [5,6]杂环化合物
公开(公告)号：US20130029964A1
公开(公告)日：2013-01-31
申请号：US13595608
申请日：2012-08-27
申请人： Kazumasa Aoki , Satoshi Matsui , Kenji Yoshikawa , Hiroki Shimizu , Junko Sasaki , Katsuyoshi Nakajima , Osamu Kanno , Kiyoshi Oizumi
发明人： Kazumasa Aoki , Satoshi Matsui , Kenji Yoshikawa , Hiroki Shimizu , Junko Sasaki , Katsuyoshi Nakajima , Osamu Kanno , Kiyoshi Oizumi
IPC分类号： A61K31/4184 , C07D471/04 , A61K31/437 , C07D235/14 , C07D401/10 , C07D413/10 , A61K31/5377 , C07D405/12 , C07D491/056 , A61K31/4188 , C07D403/10 , A61K31/496 , A61K31/506 , A61K31/454 , A61K31/4439 , A61P19/08 , A61P19/10 , C07D235/12
CPC分类号： C07D235/06 , A61K31/4184 , A61K31/4188 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D403/04 , C07D405/12 , C07D405/14 , C07D417/04 , C07D471/04 , C07D491/056
摘要： An object of the present invention is to provide a novel low molecular weight compound exhibiting an osteogenesis-promoting action. This object is achieved by a compound having the general formula (I) or a pharmacologically acceptable salt thereof. In the general formula (I), R1 and R2 represent hydrogen atoms, and the like; R3 represents a hydrogen atom, and the like; X, Y, and Z represent nitrogen atoms, and the like; A represents a phenylene group, and the like; n represents 1 or 2, and the like; and V and W represent oxygen atoms, and the like.
摘要翻译：本发明的目的是提供一种表现出成骨促进作用的新型低分子量化合物。该目的通过具有通式（I）的化合物或其药理学上可接受的盐来实现。在通式（I）中，R 1和R 2表示氢原子等; R3表示氢原子等; X，Y和Z表示氮原子等; A表示亚苯基等; n表示1或2，等等; V和W表示氧原子等。

2. 发明申请

US20110060228A1 METHOD AND APPARATUS FOR EVALUATING FLUIDITY OF BLOOD 审中-公开
标题翻译：用于评估血液流动性的方法和装置
公开(公告)号：US20110060228A1
公开(公告)日：2011-03-10
申请号：US12836417
申请日：2010-07-14
申请人： Shinji Koshino , Hiroki Shimizu , Kyoko Shimizu , Hiroo Sato
发明人： Shinji Koshino , Hiroki Shimizu , Kyoko Shimizu , Hiroo Sato
IPC分类号： A61B5/026 , A61B6/00
CPC分类号： A61B5/0261 , A61B5/02028 , A61B5/02416 , A61B5/6826 , A61B5/6838
摘要： In order to supply a method and a device that can evaluate the fluidity of blood with good sensitivity in a simple manner, there is provided a blood fluidity evaluation method in which a pressure member is pressed against a test site upon a test subject, blood at the test site is squeezed to flow out to the periphery of the test site, change over time of the amount of blood at the test site is measured at this time using optical scattering, and blood fluidity at the test site is evaluated from this measurement data; and, desirably, before the above method, a positioning process is performed in which: the pressure member is pressed against the test site with a weak force; pulse measurement data is acquired due to the absorption of light; and a relative position, at which the intensity of the pulse measurement data attains a local maximum, is determined as being an optimum measurement position.
摘要翻译：为了提供能够以简单的方式以良好的灵敏度评估血液的流动性的方法和装置，提供了一种血液流动性评价方法，其中将压力构件压在测试对象的测试位置，血液在测试部位被挤压流出到测试部位的周围，此时使用光学散射测量在测试部位的血液量的变化，并且从该测量数据评估测试部位的血液流动性 ; 并且期望地在上述方法之前，执行定位处理，其中：压力构件以弱的力压在测试地点上; 由于吸收光而获取脉冲测量数据; 以及脉冲测量数据的强度达到局部最大值的相对位置被确定为最佳测量位置。

3. 发明授权

US4363043A Circuit arrangement for skipping marked portions of a recording tape 失效
标题翻译：用于跳过记录带的标记部分的电路布置
公开(公告)号：US4363043A
公开(公告)日：1982-12-07
申请号：US169474
申请日：1980-07-16
申请人： Masatsugu Kitamura , Hideo Onoye , Hiroki Shimizu
发明人： Masatsugu Kitamura , Hideo Onoye , Hiroki Shimizu
IPC分类号： G11B15/087 , G11B15/00 , G11B27/10 , G11B27/30 , G11B17/00
CPC分类号： G11B15/005 , G11B27/107 , G11B27/3018 , G11B2220/90
摘要： An automatic skipping control circuit includes a voltage controlled, variable frequency filter having a passband frequency variable in accordance with the voltage of a frequency control signal applied thereto. This filter is responsive to an output signal from a transducer head representative of materials recorded in a tape where a skip-mark signal is recorded in selected portions. The filter is normally tuned to the frequency of the skip mark signal when the tape is transported at normal playing speed. Upon the leading edge of a skip-mark recorded portion reaching the transducer head, the filter provides an output signal which causes the tape to be driven in the fast-forward mode, resulting in an increase in the frequency of the skip-mark signal detected by the transducer head. The frequency control signal is generated during this fast-forward mode to vary the passband frequency of the filter to correspond to the increased frequency of the detected skip-mark signal. Since the speed of the tape measured at the transducer head during the fast-forward mode varies as a function of the diameter of the convolutions of the tape wound on a takeup reel, the voltage of the frequency control signal is varied as a function of this diameter to keep track of the varying frequency of the detected skip-mark signal.
摘要翻译：自动跳跃控制电路包括具有根据施加到其上的频率控制信号的电压而具有通带频率可变的电压控制的可变频率滤波器。该滤波器响应来自代表记录在磁带中的材料的传感器头的输出信号，其中跳过标记信号被记录在选定部分中。当磁带以正常播放速度传输时，滤波器通常调谐到跳过标记信号的频率。在跳跃标记记录部分到达换能器头部的前缘时，滤波器提供输出信号，该输出信号使得磁带以快进模式被驱动，导致检测到的跳过标记信号的频率增加由换能器头。在该快进模式期间产生频率控制信号以改变滤波器的通带频率以对应于检测到的跳过标记信号的增加的频率。由于在快进模式期间在换能器头处测量的带的速度作为卷绕在卷取卷轴上的带的卷绕直径的函数而变化，所以频率控制信号的电压作为该函数而变化以跟踪检测到的跳过标记信号的变化频率。

4. 发明授权

US4259119A Boride-based refractory materials 失效
$Boride-based refractory materials$
标题翻译：硼化物耐火材料
公开(公告)号：US4259119A
公开(公告)日：1981-03-31
申请号：US89487
申请日：1979-10-30
申请人： Tadahiko Watanabe , Hiroki Shimizu
发明人： Tadahiko Watanabe , Hiroki Shimizu
IPC分类号： C22C29/12 , C04B35/58 , C22C29/14
CPC分类号： C04B35/58071 , C04B35/5156 , C04B35/5805 , C04B35/58064 , C04B35/58078 , C04B35/6303 , C04B35/645
摘要： A novel high strength, high heat resistance sintered body suitable for use as refractory and abrasive materials is proposed. The sintered body comprises from 99.99 to 70% by weight of a combination of at least two kinds of metal diborides selected from the group consisting of diborides of Ti, Ta, Cr, Mn, Mo, Y, V, Hf, Nb, Al and Zr and from 0.01 to 30% by weight of a metal boride or borides selected from the group consisting of borides of nickel, iron and cobalt.The sintered body of the invention can be prepared by sintering the powdery mixture of the components at a relatively low temperature of 1800.degree. C. or lower and has a bending strength as high as 190 kg/mm.sup.2 and a Vickers hardness of 3300 kg/mm.sup.2 at room temperature and 2400 kg/mm.sup.2 at 1000.degree. C.
摘要翻译：提出一种适用于耐火材料和研磨材料的新型高强度，高耐热烧结体。烧结体包含99.99〜70重量％的选自Ti，Ta，Cr，Mn，Mo，Y，V，Hf，Nb，Al的二硼化物和至少两种金属二硼化物的组合， Zr和0.01-30重量％的选自镍，铁和钴的硼化物的金属硼化物或硼化物。本发明的烧结体可以通过在1800℃以下的相对较低的温度下烧结组分的粉末状混合物并具有高达190kg / mm 2的弯曲强度和3300kg / mm 2的维氏硬度来制备在室温下为2400kg / mm 2，在1000℃

5. 发明授权

US4021205A Sintered powdered ferrous alloy article and process for producing the alloy article 失效
标题翻译：烧结粉末铁合金制品及其制造方法
公开(公告)号：US4021205A
公开(公告)日：1977-05-03
申请号：US693770
申请日：1976-06-08
申请人： Takayuki Matsuda , Yoichi Shimizu , Hiroki Shimizu , Kazushi Imazaki , Setsuo Nii
发明人： Takayuki Matsuda , Yoichi Shimizu , Hiroki Shimizu , Kazushi Imazaki , Setsuo Nii
IPC分类号： B22F1/00 , C22C19/07 , C22C33/02 , C22C38/00 , B22F3/00
CPC分类号： C22C33/0207
摘要： A sintered powdered ferrous alloy article having high heat and abrasion resistances and a high workability is produced by admixing, (1) 5 to 30% by weight of a finely divided component alloy which consists of the following composition,______________________________________ 1 to 4% by weight carbon 10 to 30% by weight chromium 2 to 15% by weight nickel 10 to 30% by weight molybdenum 20 to 40% by weight cobalt 1 to 5% by weight niobium the balance iron, ______________________________________ (2) 0.8 to 2% by weight of finely divided carbon and (3) the balance of a finely divided ferrous base metal, compression molding the admixture under a pressure of 4 to 6 metric tons/cm.sup.2 and sintering the molded admixture in a reducing atmosphere at a temperature of 1050.degree. to 1150.degree. C, the resultant alloy article comprising a matrix component formed from the finely divided carbon and ferrous base metal, numerous particles of the finely divided component alloy dispersed in the matrix and bounding phases formed, around the particles of the finely divided component alloy, from a portion of the matrix and portions of the finely divided component alloy diffused into the portions of the matrix.
摘要翻译：通过混合（1）5〜30重量％的由以下组成组成的细分成分合金，制造具有高耐热耐磨性和高加工性的烧结铁粉合金制品，1〜4重量％碳} 10〜30重量％的铬} 2〜15重量％的镍} 10〜30重量％的钼} 20〜40重量％的钴} 1〜5重量％的铌}余量的铁，}（2） 0.8至2％重量的精细分选碳和（3）精细分离的富碱基金属的平衡，压缩成型4至6公吨/ CM2压力下的粘合剂，并在A A中减少大气中的成型混合物 1050〜1150℃的温度，所得的合金制品包括由细碎的碳和铁基金属形成的基体组分，分散在基质中的细分散组分合金的许多颗粒和形成的界面相细分成分合金，从基体的一部分和细分散的组分合金的部分扩散到基体的部分。

6. 发明授权

US08171910B2 Cylinder liner, cylinder block and process for the preparation of cylinder liner 有权
标题翻译：气缸套，缸体和气缸套的制备过程
公开(公告)号：US08171910B2
公开(公告)日：2012-05-08
申请号：US12552813
申请日：2009-09-02
申请人： Yuki Tachibana , Yoshiro Shina , Makoto Miyasaka , Hiroki Shimizu , Daisuke Shinkai
发明人： Yuki Tachibana , Yoshiro Shina , Makoto Miyasaka , Hiroki Shimizu , Daisuke Shinkai
IPC分类号： F02F1/00
CPC分类号： F02F1/004
摘要： The present invention a cylinder liner which controls gap formation at the interface between the cylinder liner and a cylinder block main body for accepting the cylinder liner therein, and serves to acquire closely contacting state and enhanced bonding strength between the cylinder liner and the cylinder block main body, and to provide a cylinder block, and further to provide a process for the preparation of the cylinder liner.A plurality of circumferential grooves 15 extending in the circumferential direction is formed from a first circumferential groove 16 having a shape of “J” of the alphabet in sectional view and extending in a circumferential direction formed on an outer surface 12 of an cast iron cylinder liner 10, and a second circumferential groove 18 having a shape of “J” of the alphabet in sectional view and linking to the first circumferential groove 16. In enclosing the cylinder liner 10 in a cylinder block main body 30 by casting, the movement of a molten aluminum alloy is depressed by the circumferential grooves 15 and therefore a residual stress generated on the solidification and shrinkage is equally dispersed whereby cracking of the cylinder block body 3 can be prevented and close contact and bonding strength at interface between the cylinder liner 10 and the cylinder block main body 30 are ensured.
摘要翻译：本发明是一种气缸套，其控制气缸套与缸体主体之间的界面处的间隙形成，用于接纳气缸套，并且用于获得气缸套和气缸体主体之间的紧密接触状态和增强的接合强度并且提供气缸体，并且还提供用于制备气缸套的过程。沿圆周方向延伸的多个周向槽15由具有字母“J”的剖面图形的第一周向槽16形成，并且沿圆周方向延伸，形成在铸铁气缸套的外表面12上以及第一圆周凹槽18，其剖面图中具有字母表“J”的形状，并与第一周向凹槽16相连。通过铸造将汽缸套10封装在汽缸体主体30中，熔融铝合金被周向槽15压下，因此在凝固和收缩时产生的残余应力相等地分散，从而可以防止缸体主体3的裂纹，并且气缸套10与缸套10之间的界面处的紧密接触和接合强度确保气缸体主体30。

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