专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20040106190A1 Flow-through assay devices 审中-公开
标题翻译：流通测定装置
公开(公告)号：US20040106190A1
公开(公告)日：2004-06-03
申请号：US10308926
申请日：2002-12-03
申请人： Kimberly-Clark Worldwide, Inc.
发明人： Kaiyuan Yang , Xuedong Song , Kevin Peter McGrath , Rameshbabu Boga , Shawn Ray Feaster , David Cohen
IPC分类号： C12M001/34
CPC分类号： G01N33/5438
摘要： A flow-through assay device capable of detecting the presence or quantity of an analyte of interest is provided. The device is in communication with an electrochemical biosensor that utilizes detection and calibration working electrodes that communicate with affinity reagents, such as redox mediators and capture ligands. For instance, capture ligands that are specific binding members for the analyte of interest may be applied to the detection electrode to serve as the primary location for detection of the analyte. The calibration working electrode may be used to calibrate the detection working electrode for any intrinsic background current not generated by the reagents of the biosensor system. Moreover, capture ligands that are non-specific binding members for the analyte of interest may also be applied to the calibration electrode. In such instances, the calibration electrode may be used to calibrate the detection working electrode for any non-specific binding that may contribute to the current generated on the surface thereof.
摘要翻译：提供了能够检测感兴趣的分析物的存在或数量的流通测定装置。该装置与电化学生物传感器连通，其利用与亲和试剂如氧化还原介体和捕获配体进行通信的检测和校准工作电极。例如，可以将作为感兴趣分析物的特异性结合成员的捕获配体施加到检测电极，以用作检测分析物的主要位置。校正工作电极可用于校准检测工作电极，用于由生物传感器系统的试剂不产生的任何本征背景电流。此外，也可以将用于感兴趣分析物的非特异性结合成分的捕获配体施加到校准电极。在这种情况下，校准电极可以用于校准检测工作电极，用于任何可能有助于在其表面上产生的电流的非特异性结合。

IPRDB

热门服务

关于我们

友情链接

联系方式