专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5804597A Agent for the prevention or treatment of cataracts 失效
标题翻译：用于预防或治疗白内障的药剂
公开(公告)号：US5804597A
公开(公告)日：1998-09-08
申请号：US779097
申请日：1997-01-06
申请人： Jun Yamakoshi , Toshiaki Ariga , Hiroharu Ishikawa , Yukihiko Iwai , Tatuo Manaka , Shigehiro Kataoka , Katsumi Yuasa , Mamoru Kikuchi
发明人： Jun Yamakoshi , Toshiaki Ariga , Hiroharu Ishikawa , Yukihiko Iwai , Tatuo Manaka , Shigehiro Kataoka , Katsumi Yuasa , Mamoru Kikuchi
IPC分类号： C07H17/065 , A61K31/35 , A61K31/352 , A61K31/353 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61K36/18 , A61P27/02 , C07D311/30 , C07D311/62
CPC分类号： A61K31/353 , Y10S514/912
摘要： An agent for the prevention or treatment of cataracts comprising a proanthocyanidin oligomer is provided. The oral administration or application to the eyes of the agent of the invention produces a sufficient preventive or therapeutic effect against cataracts caused by oxidative disorders.
摘要翻译：提供了用于预防或治疗包含原花色素寡聚物的白内障的药剂。对本发明的药剂的眼睛的口服或施用对由氧化性疾病引起的白内障产生足够的预防或治疗作用。

2. 发明授权

US6051234A Health diet for preventing diseases caused by life-habit 失效
标题翻译：用于预防因生命习惯引起的疾病的健康饮食
公开(公告)号：US6051234A
公开(公告)日：2000-04-18
申请号：US18437
申请日：1998-02-04
申请人： Shigehiro Kataoka , Akio Obata , Jun Yamakoshi , Yukihiko Iwai , Tatuo Manaka , Toru Izumi , Koichiro Tobe , Nobuyuki Yamaji
发明人： Shigehiro Kataoka , Akio Obata , Jun Yamakoshi , Yukihiko Iwai , Tatuo Manaka , Toru Izumi , Koichiro Tobe , Nobuyuki Yamaji
IPC分类号： C07D311/36 , A23G3/00 , A23G3/36 , A23L1/20 , A23L1/22 , A23L1/238 , A23L1/30 , A61K31/35 , A61K31/352 , A61P3/06 , A61P31/04 , A61P43/00 , C07D311/40 , A61K35/78 , A23L1/28 , A23L1/31
CPC分类号： A23G3/368 , A23G3/362 , A23L11/07 , A23L27/50 , A23L27/72 , A23L33/105
摘要： A health diet for preventing life-habit diseases (adult diseases) is provided.The health diet is prepared by directly encapsulating or tableting an organic solvent extract of soy sauce cakes or an aqueous alkali extract of a soy sauce oil, or blending the extracts with a diet.
摘要翻译：提供了一种用于预防生命习惯疾病（成人疾病）的健康饮食。健康饮食是通过直接包装或压片酱油蛋白的有机溶剂提取物或酱油油的碱性提取物，或者将提取物与饮食混合来制备的。

3. 发明授权

US5972357A Healthy foods and cosmetics 失效
标题翻译：健康食品和化妆品
公开(公告)号：US5972357A
公开(公告)日：1999-10-26
申请号：US975713
申请日：1997-11-21
申请人： Fumio Yamaguchi , Makoto Saito , Hiroharu Ishikawa , Shigehiro Kataoka , Toshiaki Ariga
发明人： Fumio Yamaguchi , Makoto Saito , Hiroharu Ishikawa , Shigehiro Kataoka , Toshiaki Ariga
IPC分类号： A23L1/30 , A61K8/35 , A61K8/97 , A61Q19/08 , A61K7/00
CPC分类号： A61K8/97 , A23L33/10 , A61K8/35 , A61Q19/08 , A23V2002/00 , A61K2800/522
摘要： The present invention relates to healthy foods and cosmetics. More particularly, it relates to healthy foods and cosmetics containing a polyisoprenylated benzophenone derivatives as effective ingredients and having a variety of functions for maintaining health such as anti-ulcer activity, the Maillard reaction inhibiting activity, anti-oxidation activity, reactive oxygen species scavenging activity, and anti-tumor promotion activity.
摘要翻译：本发明涉及健康食品和化妆品。更具体地说，本发明涉及含有聚异戊二烯基二苯甲酮衍生物作为有效成分的健康食品和化妆品，具有保持健康的各种功能，例如抗溃疡活性，美拉德反应抑制活性，抗氧化活性，活性氧清除活性，和抗肿瘤促进活动。

4. 发明授权

US06395280B1 Deodorant agents for oral use for discharges and method for relieving odor of discharges 有权
标题翻译：口腔使用的除臭剂及其排放物的排气方法
公开(公告)号：US06395280B1
公开(公告)日：2002-05-28
申请号：US09601117
申请日：2000-07-27
申请人： Jun Yamakoshi , Shigehiro Kataoka , Hiroshi Hosoyama , Toshiaki Ariga
发明人： Jun Yamakoshi , Shigehiro Kataoka , Hiroshi Hosoyama , Toshiaki Ariga
IPC分类号： A61K39385
CPC分类号： A61Q15/00 , A23K20/10 , A23K20/179 , A23K50/30 , A61K8/97 , A61K31/35 , A61K31/352 , A61K31/7048 , A61K36/06 , A61K36/87 , A61K2800/92 , A61K2300/00
摘要： An oral deodorant for excreta containing a proanthocyanidin as an active ingredient and a method of reducing the odor of excreta of an object comprising dosing the object with an effective amount of a proanthocyanidin.
摘要翻译：用于含有原花青素作为活性成分的排泄物的口腔除臭剂和减少对象排泄物气味的方法，包括用有效量的原花青素给药物质。

5. 发明授权

US5231193A Process for producing ellagic acid 失效
标题翻译：生产鞣花酸的方法
公开(公告)号：US5231193A
公开(公告)日：1993-07-27
申请号：US854799
申请日：1992-03-25
申请人： Kiyoshi Mizusawa , Yasuhiko Imai , Katsumi Yuasa , Hirokazu Koyama , Nobuyuki Yamaji , Shigehiro Kataoka , Tetsuya Oguma
发明人： Kiyoshi Mizusawa , Yasuhiko Imai , Katsumi Yuasa , Hirokazu Koyama , Nobuyuki Yamaji , Shigehiro Kataoka , Tetsuya Oguma
IPC分类号： C07D493/06
CPC分类号： C07D493/06
摘要： A process for producing ellagic acid comprising reacting a tannin having gallic acid residues attached as constituents with an oxidizing agent at pH 7 or higher.
摘要翻译：一种生产鞣花酸的方法，包括使具有作为成分附着的没食子酸残基的单宁与pH7或更高的氧化剂反应。

6. 发明授权

US5246922A N.sup.6,N.sup.6 -disubstituted-cyclic adenosine-3',5'-monophosphates and pharmacutical compositions 失效
标题翻译： N6，N6-二取代 - 环腺苷-3'，5'-单磷酸酯和药物组合物
公开(公告)号：US5246922A
公开(公告)日：1993-09-21
申请号：US571188
申请日：1990-08-23
申请人： Shigehiro Kataoka , Nobuyuki Yamaji , Motohiko Kato , Shoichi Imai
发明人： Shigehiro Kataoka , Nobuyuki Yamaji , Motohiko Kato , Shoichi Imai
IPC分类号： C07H19/213 , A61K31/70 , A61K31/7042 , A61K31/7052 , A61K31/7076 , A61P9/04 , C07H19/20
CPC分类号： C07H19/20 , Y02P20/55
摘要： The present invention relates to a N.sup.6,N.sup.6 -disubstituted-cyclic adenosine-3',5'-monophosphate represented by the formula ##STR1## wherein R represents a linear alkyl group having 3 or more carbon atoms or a branched alkyl group having 4 or more carbon atoms, an aralkyl group or an alkenyl group; A.sup..sym. represents a hydrogen ion, an alkali metal ion, an alkaline earth metal ion, an ammonium ion or an organoammonium ion, or a salt thereof, and a cardiac composition comprising it as an effective component, and further includes a process for preparing a compound represented by the formula ##STR2## wherein R.sub.1 represents an alkyl group, an aralkyl group or an alkenyl group and A.sup..sym. has the same meanings as defined above, or a salt thereof, characterized in that a 2'-O-protected-cyclic adenosine-3',5'-monophosphate represented by the formula ##STR3## wherein Y represents a protecting group and A.sup..sym. has the same meanings as defined above, or a salt thereof is reacted with an organic halide represented by the formulaR.sub.1 X (III) wherein X represents a halogen atom and R.sub.1 has the same meanings as defined above, and the protecting group is then removed.
摘要翻译：本发明涉及由式（I）表示的N6，N6-二取代环腺苷-3'，5'-单磷酸酯，其中R表示具有3个或更多个碳原子的直链烷基或支链烷基具有4个或更多个碳原子，芳烷基或烯基; A（+）表示氢离子，碱金属离子，碱土金属离子，铵离子或有机铵离子或其盐，以及包含其作为有效成分的心脏组合物，还包括制备由式（I'）表示的化合物，其中R 1表示烷基，芳烷基或烯基，A（+）具有与上述相同的含义或其盐，其特征在于，或其盐，其中Y表示保护基，A（+）与上述相同的含义，由式（II）表示的2'-O-保护环腺苷-3'，5'-单磷酸与式R1X（III）表示的有机卤化物反应，其中X表示卤素原子，R 1具有与上述相同的含义，然后除去保护基。

7. 发明授权

US4902677A Treatment of heart failure of mammals with N.sup.6 -substituted cyclic adenosine monophosphates 失效
标题翻译：用N6-取代的环状腺苷单磷酸酯治疗哺乳动物的心力衰竭
公开(公告)号：US4902677A
公开(公告)日：1990-02-20
申请号：US159747
申请日：1988-02-24
申请人： Shoichi Imai , Shigehiro Kataoka , Junko Isono , Nobuyuki Yamaji , Motohiko Kato
发明人： Shoichi Imai , Shigehiro Kataoka , Junko Isono , Nobuyuki Yamaji , Motohiko Kato
IPC分类号： C07H19/213 , A61K31/70 , A61K31/7042 , A61K31/7052 , A61K31/7076 , A61P9/04 , C07H19/20
CPC分类号： C07H19/20
摘要： A composition for use in the treatment of heart failure of mammals which comprises, as its active ingredient, an N.sup.6 -substututed-adenosine-3',5'-cyclic phosphate represented by the following general formula (I) or a physiologically acceptable salt thereof: ##STR1## wherein R represents alkyl or aralkyl group and a pharmaceutically acceptable carrier, as well as a method for treating heart failure of mammals which comprises administering said composition.
摘要翻译：一种用于治疗哺乳动物心力衰竭的组合物，其包含作为其活性成分的由以下通式（I）表示的N 6 - 亚基 - 腺苷-3'，5'-环磷酸酯或其生理学上可接受的盐：其中R表示烷基或芳烷基和药学上可接受的载体，以及用于治疗哺乳动物心力衰竭的方法，其包括施用所述组合物。

8. 发明授权

US4567254A Method for preparing N.sup.6,8-disubstituted 3',5'-cyclic adenosine monophosphate and salt thereof 失效
标题翻译：制备N6,8-二取代的3'，5'-环腺苷单磷酸及其盐的方法
公开(公告)号：US4567254A
公开(公告)日：1986-01-28
申请号：US652093
申请日：1984-09-19
申请人： Shigehiro Kataoka , Takashi Nakamura , Nobuyuki Yamaji , Seiichi Nasuno
发明人： Shigehiro Kataoka , Takashi Nakamura , Nobuyuki Yamaji , Seiichi Nasuno
IPC分类号： C07H19/20 , C07H15/12 , C07H17/00
CPC分类号： C07H19/20
摘要： A method for preparing an N.sup.6,8-disubstituted 3',5'-cyclic adenosine monophosphate or a salt thereof represented by the general formula ##STR1## wherein X denotes a halogen atom or ##STR2## N.sub.3, OH or OR, R being an alkyl or aralkyl group; A.sup..sym. denotes a hydrogen ion, alkali metal ion, ammonium ion or organic ammonium ion; and R.sub.1 denotes an alkyl or aromatic group, which method comprises reacting an 8-substituted 3',5'-cyclic adenosine monophosphate or a salt thereof represented by the general formula (II) ##STR3## wherein X and A.sup.61 are as defined above, with an aldehyde represented by the general formulaR.sub.1 --CHO (III)wherein R.sub.1 is as defined above, to form an imine compound represented by the general formula ##STR4## wherein X, R.sub.1 and A.sup..sym. are as defined above, as an intermediate, and then reducing the imine compound.
摘要翻译：一种制备由通式（I）表示的N6,8-二取代的3'，5'-环腺苷单磷酸或其盐的方法，其中X表示卤素原子或N 3，OH或OR， R为烷基或芳烷基; A（+）表示氢离子，碱金属离子，铵离子或有机铵离子; 并且R 1表示烷基或芳基，该方法包括使由通式（II）表示的8-取代的3'，5'-环腺苷一磷酸或其盐，其中X和A61为（IV）表示的亚胺化合物，其中X，R 1和A（+）是如上定义的，其中R 1如上所定义，通式为R1-CHO 如上所定义，作为中间体，然后还原亚胺化合物。

9. 发明授权

US4751293A Process for preparation of N.sup.6 -substituted 3',5'-cyclic adenosine monophosphate and salt thereof 失效
标题翻译：制备N6-取代的3'，5'-环腺苷一磷酸及其盐的方法
公开(公告)号：US4751293A
公开(公告)日：1988-06-14
申请号：US727062
申请日：1985-04-25
申请人： Shigehiro Kataoka , Ayako Nasu , Nobuyuki Yamaji , Motohiko Kato
发明人： Shigehiro Kataoka , Ayako Nasu , Nobuyuki Yamaji , Motohiko Kato
IPC分类号： C07H19/213 , C07H1/00 , C07H19/20 , C07H15/12 , C07H17/00
CPC分类号： C07H19/20
摘要： A method for the preparation of an N.sup.6 -substituted 3',5'-cyclic adenosine monophosphate or a salt thereof represented by the general formula ##STR1## wherein R.sub.1 represents a straight chain or branched chain alkyl group of 1 to 13 carbon atoms or an aromatic group and B.sym. represents a hydrogen ion or an alkali metal ion, which comprises allowing a 3',5'-cyclic adenosine monophosphate or a salt thereof represented by the general formula ##STR2## wherein A.sym. represents a hydrogen ion, alkali metal ion, organic ammonium ion, or ammonium ion, to react with an aldehyde represented by the general formulaR.sub.1 CHO (III)wherein R.sub.1 is as defined above, under the conditions such that pH is 7.0 or below, the temperature is -10.degree. to 120.degree. C., and the molar ratio of the compound (II) to the compound (III) is 1:1-40, and reducing the resulting compound with a metal hydride or nascent hydrogen.
摘要翻译：一种制备由通式（I）表示的N6-取代的3'，5'-环腺苷一磷酸或其盐的方法，其中R 1表示1至13个碳的直链或支链烷基原子或芳基，B（+）表示氢离子或碱金属离子，其包括使通式（II）表示的3'，5'-环腺苷一磷酸或其盐，其中A （+）表示氢离子，碱金属离子，有机铵离子或铵离子，在通式R 1 CHO（III）表示的醛中，其中R 1如上定义，在pH为7.0或温度为-10℃〜120℃，化合物（II）与化合物（III）的摩尔比为1:1-40，用金属氢化物或新生氢还原所得化合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式