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1. 发明授权

US5804597A Agent for the prevention or treatment of cataracts 失效
标题翻译：用于预防或治疗白内障的药剂
公开(公告)号：US5804597A
公开(公告)日：1998-09-08
申请号：US779097
申请日：1997-01-06
申请人： Jun Yamakoshi , Toshiaki Ariga , Hiroharu Ishikawa , Yukihiko Iwai , Tatuo Manaka , Shigehiro Kataoka , Katsumi Yuasa , Mamoru Kikuchi
发明人： Jun Yamakoshi , Toshiaki Ariga , Hiroharu Ishikawa , Yukihiko Iwai , Tatuo Manaka , Shigehiro Kataoka , Katsumi Yuasa , Mamoru Kikuchi
IPC分类号： C07H17/065 , A61K31/35 , A61K31/352 , A61K31/353 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61K36/18 , A61P27/02 , C07D311/30 , C07D311/62
CPC分类号： A61K31/353 , Y10S514/912
摘要： An agent for the prevention or treatment of cataracts comprising a proanthocyanidin oligomer is provided. The oral administration or application to the eyes of the agent of the invention produces a sufficient preventive or therapeutic effect against cataracts caused by oxidative disorders.
摘要翻译：提供了用于预防或治疗包含原花色素寡聚物的白内障的药剂。对本发明的药剂的眼睛的口服或施用对由氧化性疾病引起的白内障产生足够的预防或治疗作用。

2. 发明授权

US6051234A Health diet for preventing diseases caused by life-habit 失效
标题翻译：用于预防因生命习惯引起的疾病的健康饮食
公开(公告)号：US6051234A
公开(公告)日：2000-04-18
申请号：US18437
申请日：1998-02-04
申请人： Shigehiro Kataoka , Akio Obata , Jun Yamakoshi , Yukihiko Iwai , Tatuo Manaka , Toru Izumi , Koichiro Tobe , Nobuyuki Yamaji
发明人： Shigehiro Kataoka , Akio Obata , Jun Yamakoshi , Yukihiko Iwai , Tatuo Manaka , Toru Izumi , Koichiro Tobe , Nobuyuki Yamaji
IPC分类号： C07D311/36 , A23G3/00 , A23G3/36 , A23L1/20 , A23L1/22 , A23L1/238 , A23L1/30 , A61K31/35 , A61K31/352 , A61P3/06 , A61P31/04 , A61P43/00 , C07D311/40 , A61K35/78 , A23L1/28 , A23L1/31
CPC分类号： A23G3/368 , A23G3/362 , A23L11/07 , A23L27/50 , A23L27/72 , A23L33/105
摘要： A health diet for preventing life-habit diseases (adult diseases) is provided.The health diet is prepared by directly encapsulating or tableting an organic solvent extract of soy sauce cakes or an aqueous alkali extract of a soy sauce oil, or blending the extracts with a diet.
摘要翻译：提供了一种用于预防生命习惯疾病（成人疾病）的健康饮食。健康饮食是通过直接包装或压片酱油蛋白的有机溶剂提取物或酱油油的碱性提取物，或者将提取物与饮食混合来制备的。

3. 发明授权

US5698585A Pharmaceutical preparation for prevention and/or treatment for cataract 失效
标题翻译：用于白内障预防和/或治疗的药物制剂
公开(公告)号：US5698585A
公开(公告)日：1997-12-16
申请号：US631424
申请日：1996-04-12
申请人： Jun Yamakoshi , Tsutomu Sasaki , Hiroharu Ishikawa , Yukihiko Iwai , Takanao Matsudo , Kenji Mori , Mamoru Kikuchi
发明人： Jun Yamakoshi , Tsutomu Sasaki , Hiroharu Ishikawa , Yukihiko Iwai , Takanao Matsudo , Kenji Mori , Mamoru Kikuchi
IPC分类号： A61K31/341 , A61K31/34
CPC分类号： A61K31/341 , Y10S514/912
摘要： In order to prevent or treat cataract, present invention features 3(2H)-furanone derivatives having 3(2H)-furanone skeleton as a main structure and/or pharmaceutically acceptable salts thereof, pharmaceutical preparations containing the derivatives and/or the salts thereof, treatment methods of cataract, and their use. The 3(2H)-furanone derivatives have excellent effects for the prevention and/or treatment of cataract, for instance, senile cataract caused by oxidation disorder. Particularly, the pharmaceutical preparations have good effect for the prevention and/or treatment of cataract when they are administrated as ophtalmics.
摘要翻译：为了防止或治疗白内障，本发明的特征在于具有3（2H） - 呋喃酮骨架的3（2H） - 呋喃酮衍生物作为主要结构和/或其药学上可接受的盐，其含有衍生物和/或其盐的药物制剂，白内障治疗方法及其应用。 3（2H） - 呋喃酮衍生物对于预防和/或治疗白内障具有优异的效果，例如由氧化障碍引起的老年性白内障。特别地，药物制剂对于预防和/或治疗白内障时具有良好的效果，当它们作为眼底液给药时。

4. 发明授权

US06395280B1 Deodorant agents for oral use for discharges and method for relieving odor of discharges 有权
标题翻译：口腔使用的除臭剂及其排放物的排气方法
公开(公告)号：US06395280B1
公开(公告)日：2002-05-28
申请号：US09601117
申请日：2000-07-27
申请人： Jun Yamakoshi , Shigehiro Kataoka , Hiroshi Hosoyama , Toshiaki Ariga
发明人： Jun Yamakoshi , Shigehiro Kataoka , Hiroshi Hosoyama , Toshiaki Ariga
IPC分类号： A61K39385
CPC分类号： A61Q15/00 , A23K20/10 , A23K20/179 , A23K50/30 , A61K8/97 , A61K31/35 , A61K31/352 , A61K31/7048 , A61K36/06 , A61K36/87 , A61K2800/92 , A61K2300/00
摘要： An oral deodorant for excreta containing a proanthocyanidin as an active ingredient and a method of reducing the odor of excreta of an object comprising dosing the object with an effective amount of a proanthocyanidin.
摘要翻译：用于含有原花青素作为活性成分的排泄物的口腔除臭剂和减少对象排泄物气味的方法，包括用有效量的原花青素给药物质。

5. 发明授权

US07718209B2 Low-salt soy sauce 有权
标题翻译：低盐酱油
公开(公告)号：US07718209B2
公开(公告)日：2010-05-18
申请号：US11575834
申请日：2005-08-05
申请人： Jun Yamakoshi , Kohsuke Matsumoto , Makoto Saito , Hitomi Aota , Takeharu Nakahara , Satoshi Fukuda , Tetsuya Oguma , Norikazu Fujii
发明人： Jun Yamakoshi , Kohsuke Matsumoto , Makoto Saito , Hitomi Aota , Takeharu Nakahara , Satoshi Fukuda , Tetsuya Oguma , Norikazu Fujii
IPC分类号： A23L1/40
CPC分类号： A23L33/185 , A23L27/50 , A23V2002/00 , A23V2200/326 , A23V2250/5488
摘要： A low common salt soy sauce, which has good flavor, significantly suppresses elevation of blood pressure, prevents cardiac hypertrophy, and is also available as special nutritious food, is obtained. 1.0% to 10.0% by weight of potassium chloride and 0.1% to 5.0% by weight of γ-aminobutyric acid are added to a reduced common salt soy sauce, so as to obtain a low common salt soy sauce of issue. Otherwise, a KCl-containing low common slat soy sauce is obtained by: (1) a common production method of soy sauce, in which a mixed solution consisting of KCl and common salt is used as mother water; (2) a method of subjecting a soy sauce obtained using saline solution as mother water to electrodialysis, a membrane treatment, or the like, so as to eliminate common salt from the above soy sauce, and then adding KCl thereto; or other methods. Thereafter, γ-aminobutyric acid is added to the above KCl-containing low common salt soy sauce, so as to obtain a low common salt soy sauce comprising 0% to 10% by weight of common salt, 1.0% to 10.0% by weight of potassium chloride, and 0.1% to 5.0% by weight of γ-aminobutyric acid.
摘要翻译：具有良好风味的低盐酱油显着抑制血压升高，预防心脏肥大，也可作为特殊营养食品使用。将1.0％至10.0％重量的氯化钾和0.1％至5.0％重量的γ-氨基丁酸加入到还原的普通盐酱油中，以获得低常见的酱油。另外，含有KCl的低普通板条酱油是通过以下方法获得的：（1）将由KCl和普通盐组成的混合溶液用作母水的酱油的常规生产方法; （2）使用盐水溶液得到的酱油作为母水进行电渗析，膜处理等，以从上述酱油中除去常见的盐，然后加入KCl; 或其他方法。然后，向上述含有KCl的低盐酱油中加入γ-氨基丁酸，得到含有0〜10重量％的普通盐，1.0〜10.0重量％氯化钾和0.1〜5.0重量％的γ-氨基丁酸。

6. 发明申请

US20080057174A1 Low-Salt Soy Sauce 有权
标题翻译：低盐酱油
公开(公告)号：US20080057174A1
公开(公告)日：2008-03-06
申请号：US11575834
申请日：2005-08-05
申请人： Jun Yamakoshi , Kohsuke Matsumoto , Makoto Saito , Hitomi Aota , Takeharu Nakahara , Satoshi Fukuda , Tetsuya Oguma , Norikazu Fujii
发明人： Jun Yamakoshi , Kohsuke Matsumoto , Makoto Saito , Hitomi Aota , Takeharu Nakahara , Satoshi Fukuda , Tetsuya Oguma , Norikazu Fujii
IPC分类号： A23L1/238
CPC分类号： A23L33/185 , A23L27/50 , A23V2002/00 , A23V2200/326 , A23V2250/5488
摘要： A low common salt soy sauce, which has good flavor, significantly suppresses elevation of blood pressure, prevents cardiac hypertrophy, and is also available as special nutritious food, is obtained. 1.0% to 10.0% by weight of potassium chloride and 0.1% to 5.0% by weight of γ-aminobutyric acid are added to a reduced common salt soy sauce, so as to obtain a low common salt soy sauce of issue. Otherwise, a KCl-containing low common salt soy sauce is obtained by: (1) a common production method of soy sauce, in which a mixed solution consisting of KCl and common salt is used as mother water; (2) a method of subjecting a soy sauce obtained using saline solution as mother water to electrodialysis, a membrane treatment, or the like, so as to eliminate common salt from the above soy sauce, and then adding KCl thereto; or other methods. Thereafter, γ-aminobutyric acid is added to the above KCl-containing low common salt soy sauce, so as to obtain a low common salt soy sauce comprising 0% to 10% by weight of common salt, 1.0% to 10.0% by weight of potassium chloride, and 0.1% to 5.0% by weight of γ-aminobutyric acid.
摘要翻译：具有良好风味的低盐酱油显着抑制血压升高，预防心脏肥大，也可作为特殊营养食品使用。将1.0％至10.0％重量的氯化钾和0.1％至5.0％的γ-氨基丁酸加入到还原的普通盐酱油中，以获得低常见的酱油。另外，含有KCl的低盐酱油是通过以下方法获得的：（1）将由KCl和普通盐组成的混合溶液用作母水的酱油的常规生产方法; （2）使用盐水溶液得到的酱油作为母水进行电渗析，膜处理等，以从上述酱油中除去常见的盐，然后加入KCl; 或其他方法。然后，向上述含有KCl的低盐酱油中加入γ-氨基丁酸，得到含有0〜10重量％的普通盐，1.0〜10.0重量％氯化钾和0.1重量％〜5.0重量％的γ-氨基丁酸。

7. 发明授权

US06264997B1 Anti-arteriosclerotic food 有权
标题翻译：抗动脉硬化食物
公开(公告)号：US06264997B1
公开(公告)日：2001-07-24
申请号：US09577359
申请日：2000-05-23
申请人： Jun Yamakoshi , Makoto Saito , Akio Obata , Toru Izumi , Koichiro Tobe
发明人： Jun Yamakoshi , Makoto Saito , Akio Obata , Toru Izumi , Koichiro Tobe
IPC分类号： A61K3578
CPC分类号： A61K36/48 , A23G3/36 , A23G3/48 , A23L2/56 , A23L33/105 , A61K36/87 , A61K2300/00
摘要： A proanthocyanidin and an isoflavone are incorporated into a food. Compounding of grape seed extract as a proanthocyanidin and soy sauce cake extract as an isoflavone gives an anti-arteriosclerotic composition that is effective at a small intake.
摘要翻译：将原花青素和异黄酮掺入食品中。将葡萄籽提取物作为原花青素和酱油饼提取物复合为异黄酮，得到抗小动脉硬化组合物，其在少量摄入中有效。

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