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1. 发明授权

US06679890B2 Method and apparatus for augmentation of the femoral neck 失效
标题翻译：用于增大股骨颈的方法和装置
公开(公告)号：US06679890B2
公开(公告)日：2004-01-20
申请号：US10199090
申请日：2002-07-22
申请人： Joseph Y. Margulies , Gamal Baroud , Thomas Steffen , Max Aebi
发明人： Joseph Y. Margulies , Gamal Baroud , Thomas Steffen , Max Aebi
IPC分类号： A61F200
CPC分类号： A61B17/742 , A61B17/7098
摘要： Combining an implant and cement for prophylactic and/or preventative use for femoral neck augmention. A hole is drilled into the femoral neck. The hole is filled with an uncured filler cement after loose materials have been removed from the hole. Then, an open-ended tube, an implant, having openings through its walls is inserted into the hole and attached to the bone. Finally, additional filler cement is provided under pressure to the inside of the tubular implant. The filler cement flows into spaces in the bone structure via the tube wall openings. A sliding leak-tight fit between the implant and a cement injection tube permits delivery of cement at preselected locations along the implant length. Pressure is maintained until the filler cement has hardened. A strengthening factor up to 3 was measured when osteoporotic bone was strengthened.
摘要翻译：结合种植体和水泥，用于股骨颈扩大的预防和/或预防性使用。在股骨颈上钻一个洞。从孔中取出松散材料后，孔中填充有未固化的填料。然后，将具有穿过其壁的开口的开口管，植入物插入孔中并附着到骨上。最后，在压力下向管状植入物的内侧提供另外的填充胶。填料粘合剂通过管壁开口流入骨结构中的空间。在植入物和水泥注射管之间的滑动密封配合允许沿着植入物长度在预选位置输送水泥。保持压力直到填料水泥硬化。当骨质疏松骨被加强时，测量了高达3的强化因子。

2. 发明授权

US6028907A System and method for three-dimensional geometric modeling by extracting and merging two-dimensional contours from CT slice data and CT scout data 失效
标题翻译：通过从CT切片数据和CT侦察数据提取和合并二维轮廓，进行三维几何建模的系统和方法
公开(公告)号：US6028907A
公开(公告)日：2000-02-22
申请号：US78522
申请日：1998-05-15
申请人： Roy Lee Adler , Alan David Kalvin , Joseph Y. Margulies , Charles P. Tresser , Chai Wah Wu
发明人： Roy Lee Adler , Alan David Kalvin , Joseph Y. Margulies , Charles P. Tresser , Chai Wah Wu
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： A61B6/032 , A61B6/4085 , A61B6/488 , A61B6/505 , Y10S378/901
摘要： A computer system and method solve the problem of getting a useful three-dimensional representation of an object like the spine using a small amount of data. This is done by gathering three-dimensional data in the form of a set of 2D computer tomography (CT) slices of a patient's bones and a coaxial set of 2D CT scout images, which are digital two-dimensional X-ray images that can be produced by a CT scanner; extracting from each of these three-dimensional data sets a corresponding stack of 2D contours; and constructing a 3D geometric model of the object. The main features of spinal deformation are captured by integrating these two sets of three-dimensional data, and constructing from them a three-dimensional geometric model of the spine. Scouts are usually used to monitor CT scan acquisition. Here, they are also used as an essential source of data.
摘要翻译：计算机系统和方法解决了使用少量数据来获得诸如脊柱的对象的有用的三维表示的问题。这是通过以一组患者骨骼的2D计算机断层摄影（CT）切片和2D CT侦察图像的同轴组的形式收集三维数据来完成的，其是可以是数字二维X射线图像由CT扫描仪产生; 从这些三维数据集中的每一个提取相应的2D轮廓的堆叠; 并构建对象的3D几何模型。通过整合这两组三维数据来捕获脊柱变形的主要特征，并从中构建脊柱三维几何模型。侦察兵通常用于监测CT扫描采集。在这里，它们也被用作数据的重要来源。

3. 发明授权

US6086590A Cable connector for orthopaedic rod 有权
标题翻译：矫形杆用电缆连接器
公开(公告)号：US6086590A
公开(公告)日：2000-07-11
申请号：US241980
申请日：1999-02-02
申请人： Joseph Y. Margulies , Matthew N. Songer , Francis J. Korhonen
发明人： Joseph Y. Margulies , Matthew N. Songer , Francis J. Korhonen
IPC分类号： A61B17/70 , A61B17/84 , A61B17/58
CPC分类号： A61B17/7053 , A61B17/842
摘要： A connector for securing surgical cable or wire to an implantable surgical rod or the like. The connector comprises a connector body having an open space for receiving the surgical rod or similar support device. The body carries a lock member for firmly affixing the connector and the rod together in a desired position along the rod. Typically, the lock member is a set screw. The connector also has a retention member carried on the connector in a rotatable manner. The retention member, typically in ring form, defines at least one bore extending there through for receiving the cable or wire, and retaining it in a desired position relative to the rod. Thus, tension can be placed upon broken bones or the like from a desired, controllable direction and with a desired magnitude of tension.
摘要翻译：用于将手术电缆或线固定到可植入手术杆等的连接器。连接器包括具有用于接收外科手术杆或类似支撑装置的开放空间的连接器本体。主体承载锁定构件，用于将连接器和杆牢固地固定在沿杆的期望位置。通常，锁定构件是固定螺钉。连接器还具有可旋转的方式承载在连接器上的保持构件。保持构件通常为环形，限定了至少一个在其上延伸的孔，用于接收电缆或电线，并将其保持在相对于杆的期望位置。因此，张力可以从期望的，可控制的方向和期望的张力大小放置在骨折等处。

4. 发明授权

US5542847A Method, apparatus and device for dental prosthesis implantation 失效
标题翻译：用于牙科假体植入的方法，装置和装置
公开(公告)号：US5542847A
公开(公告)日：1996-08-06
申请号：US303438
申请日：1994-09-09
申请人： Joseph Y. Margulies
发明人： Joseph Y. Margulies
IPC分类号： A61C1/08 , A61C8/00
CPC分类号： A61C1/084 , A61C8/0009 , A61C8/001
摘要： A dental implant, placed into a socket formed in the jaw bone, is held in position by screws that pass through the jaw bone from the buccal cortical surface to the lingual cortical surface, and through the implant that is located between the cortical surfaces. Threads on the screw shank form and engage threads in the cortex on opposite sides of the jaw bone. The implant, when inserted in the socket and anchored by the screws, is immediately strongly held to the jaw's bony structure. Stresses applied to a prosthetic device, e.g., a tooth crown that is attached to the implant, are substantially borne by the cortex by way of the screws.
摘要翻译：放置在形成在颚骨中的插座中的牙科植入物通过穿过颚骨从颊皮质表面到舌侧皮质表面以及通过位于皮质表面之间的植入物的螺钉保持就位。螺钉柄上的螺纹形成并接合在颚骨相对侧的皮层中的螺纹。当植入物插入插座并被螺钉固定时，立即牢固地固定在颌骨的骨骼结构上。应用于假体装置，例如附着于植入物的牙冠，其基本上由皮质由螺钉承载。

5. 发明授权

US6023495A System and method for acquiring three-dimensional data subject to practical constraints by integrating CT slice data and CT scout images 失效
标题翻译：通过集成CT切片数据和CT侦察图像获取实际约束的三维数据的系统和方法
公开(公告)号：US6023495A
公开(公告)日：2000-02-08
申请号：US79515
申请日：1998-05-15
申请人： Roy Lee Adler , Alan David Kalvin , Joseph Y. Margulies , Charles P. Tresser , Chai Wah Wu
发明人： Roy Lee Adler , Alan David Kalvin , Joseph Y. Margulies , Charles P. Tresser , Chai Wah Wu
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： A61B6/032 , A61B6/4085 , A61B6/488 , A61B6/505 , Y10S378/901
摘要： A computer system and method solve the problem of getting a useful three-dimensional representation of an object like the spine using a small amount of data. This is done by gathering and combining three-dimensional data in the form of (a) a set of 2D computer tomography (CT) slices of a patient's bones with (b) a set of 2D CT scout images, which are digital two-dimensional X-ray images that can be produced by a CT scanner. The main features of spinal deformation are captured by integrating these two sets of three-dimensional data, and constructing from them a three-dimensional geometric model of the spinal. Scouts are usually used to monitor CT scan acquisition. Here, they are also used as an essential source of data.
摘要翻译：计算机系统和方法解决了使用少量数据来获得诸如脊柱的对象的有用的三维表示的问题。这是通过以（a）患者骨骼的一组2D计算机断层摄影（CT）切片的形式收集和组合三维数据来完成的，（b）一组2D CT侦察图像，其是数字二维可以由CT扫描仪生产的X射线图像。脊柱变形的主要特征是通过整合这两组三维数据，并从中构建脊柱三维几何模型。侦察兵通常用于监测CT扫描采集。在这里，它们也被用作数据的重要来源。

6. 发明授权

US5562735A Spinal stabilization system and improved method 失效
标题翻译：脊柱稳定系统和改进方法
公开(公告)号：US5562735A
公开(公告)日：1996-10-08
申请号：US145603
申请日：1993-11-04
申请人： Joseph Y. Margulies
发明人： Joseph Y. Margulies
IPC分类号： A61B17/17 , A61B17/70 , A61F2/10
CPC分类号： A61B17/7052 , A61B17/1757
摘要： A spinal stabilization system for fixing affected vertebrae having anterior and posterior aspects. The system comprises a plurality of rods or plates disposed over the affected vertebrae, at least one rod or plate disposed anteriorly and at least one disposed posteriorly, and a plurality of bolts and nuts extending laterally through the affected vertebrae and attached to the rods.
摘要翻译：用于固定患有前后方面的椎骨的脊柱稳定系统。该系统包括设置在受影响的椎骨上的多个杆或板，至少一个杆或板，其位于前方且至少一个设置在后方，以及多个螺栓和螺母，其横向延伸穿过受影响的椎骨并附接到杆。

7. 发明授权

US06662148B1 Computation of shapes of three-dimensional linkage structures based on optimization techniques 失效
标题翻译：基于优化技术计算三维连杆结构的形状
公开(公告)号：US06662148B1
公开(公告)日：2003-12-09
申请号：US09493146
申请日：2000-01-28
申请人： Roy L. Adler , Jean-Pierre Dedieu , Alan D. Kalvin , Joseph Y. Margulies , Marco Martens , Michael Shub
发明人： Roy L. Adler , Jean-Pierre Dedieu , Alan D. Kalvin , Joseph Y. Margulies , Marco Martens , Michael Shub
IPC分类号： G06G748
CPC分类号： G09B23/32 , G09B23/30
摘要： Spinal modeling is based on a concept called spinal energy which assumes that the spine assumes a shape to minimize spinal energy. Spinal energy depends on parameters called stiffness coefficients. These parameters can be determined from human data which, by hypothesis, are universal for a large class of humans. The method adapts Newton's method to the manifold SO(3)n to find a solution of model of the human spine. Where basins of attraction are small in Newton's method, homotopy methods are introduced to move from known solutions to unknown solutions. By setting the gradient of the spinal energy to zero, Newton's method is used to solve the inverse problem of finding stiffness coefficients from human data. A new approach to improving deformed spines uses the modeling method based on spinal energy. This approach preserves maximally the range of motion of the spine. The technique used is vertebraplasty; i.e., adding and/or subtracting material surgically from various vertebral bodies without fusing or altering soft tissue. An interactive process is used to determine the surgery to be performed to improve spinal shape.
摘要翻译：脊柱建模基于一种称为脊椎能量的概念，其假定脊柱呈现为使脊椎能量最小化的形状。脊柱能量取决于称为刚度系数的参数。这些参数可以从人类数据中确定，根据假设，人类数据对于大类人类是普遍的。该方法将牛顿法适应于歧管SO（3），以找到人类脊柱模型的解。在牛顿法的吸引力小的地方，引入同伦方法从已知解决方案转移到未知解决方案。通过将脊柱能量的梯度设置为零，使用牛顿法来解决从人类数据中找到刚度系数的逆问题。改进变形脊柱的新方法使用基于脊椎能量的建模方法。这种方法最大限度地保留了脊柱的运动范围。使用的技术是椎体成形术即从各种椎体外科手术加入和/或减去材料，而不会熔化或改变软组织。使用交互过程来确定要进行的手术以改善脊柱形状。

8. 发明授权

US5946370A System and method for accessing the three-dimensional geometry of large objects using X-ray based method subject to limitations on radiation doses 失效
标题翻译：使用基于X射线的方法对受限于辐射剂量的大对象的三维几何进行访问的系统和方法
公开(公告)号：US5946370A
公开(公告)日：1999-08-31
申请号：US62276
申请日：1998-04-15
申请人： Roy Lee Adler , Nogah Haramati , Alan David Kalvin , Joseph Y. Margulies , Charles P. Tresser , Chai Wah Wu
发明人： Roy Lee Adler , Nogah Haramati , Alan David Kalvin , Joseph Y. Margulies , Charles P. Tresser , Chai Wah Wu
IPC分类号： G06T11/00 , G06T17/00 , A61B6/03
CPC分类号： G06T17/00 , G06T11/006 , G06T2211/436 , Y10S378/901
摘要： A computer system and method solve the problem of getting a useful three dimensional representation of an object like the spine using a small amount of data. This is done by gathering and combining three dimensional data in the form of computer tomography (CT) scans of a patient's bones with two dimensional data consisting of CT scout images (or scouts), which are digital two dimensional X-ray images that can be produced by a CT scanner. The main features of spinal deformation are captured by combining the two dimensional data from CT scouts and the three-dimensional information from the CT scans using simple modeling of vertebrae. Scouts are usually used to monitor CT scan acquisition. Here, they are also used as an essential source of data.
摘要翻译：计算机系统和方法解决了使用少量数据来获得像脊柱的对象有用的三维表示的问题。这是通过收集和组合患者骨骼的计算机断层摄影（CT）扫描形式的三维数据与由CT侦察图像（或侦察器）组成的二维数据来完成的，这些数据是可以是数字二维X射线图像由CT扫描仪产生。脊柱变形的主要特征是通过使用简单的椎骨建模结合来自CT侦察的二维数据和来自CT扫描的三维信息来捕获。侦察兵通常用于监测CT扫描采集。在这里，它们也被用作数据的重要来源。

9. 发明授权

US5700292A Spinal stabilization system and method 失效
标题翻译：脊柱稳定系统及方法
公开(公告)号：US5700292A
公开(公告)日：1997-12-23
申请号：US528801
申请日：1995-09-15
申请人： Joseph Y. Margulies
发明人： Joseph Y. Margulies
IPC分类号： A61B17/17 , A61B17/70 , A61F2/10
CPC分类号： A61B17/7052 , A61B17/1757
摘要： A spinal stabilization system for fixing vertebrae and sacrum having anterior and posterior aspects. The system comprises a plurality of rods or plates disposed over the vertebrae and/or sacrum, at least one rod or plate disposed anteriorly and at least one disposed posteriorly, and a plurality of bolts and nuts extending laterally through said vertebrae and/or sacrum and attached to the rods. A method for installing a spinal stabilization system to fix vertebrae and/or sacrum, comprising the steps of: exposing the spine anteriorly and posteriorly to reveal a level of vertebrae and/or sacrum, inserting a pair of beam means through the vertebrae and/or sacrum; repeating the exposing and inserting steps for a next level of vertebrae and/or sacrum; disposing column means over the anterior and posterior aspects of the two levels of vertebrae and/or sacrum; and connecting the ends of the beam means at each vertebrae and/or sacrum level to the column means.
摘要翻译：用于固定具有前后方面的椎骨和骶骨的脊柱稳定系统。该系统包括设置在椎骨和/或骶骨之上的多个杆或板，至少一个杆或板，其位于前方且至少一个设置在后方，以及多个螺栓和螺母，横向延伸穿过所述椎骨和/或骶骨，连接到杆上。一种用于安装脊椎稳定系统以固定椎骨和/或骶骨的方法，包括以下步骤：将脊柱前部和后部暴露以露出一定程度的椎骨和/或骶骨，将一对梁装置穿过椎骨和/或骶骨重复下一级椎骨和/或骶骨的暴露和插入步骤; 在两级椎骨和/或骶骨的前后方面设置柱装置; 并且将每个椎骨和/或骶骨水平处的梁装置的端部连接到柱装置。

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