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    • 10. 发明授权
    • System and method for deploying a drug-eluting external body and tissue scaffold
    • 用于部署药物洗脱外部身体和组织支架的系统和方法
    • US07491225B2
    • 2009-02-17
    • US11059242
    • 2005-02-16
    • Jan WeberBrian J. BrownRichard C. GundersonSusan Shoemaker
    • Jan WeberBrian J. BrownRichard C. GundersonSusan Shoemaker
    • A61F2/06
    • A61F2/915A61F2/07A61F2/90A61F2/91A61F2/966A61F2002/075A61F2002/91541A61F2002/91558A61F2220/005A61F2220/0058A61F2230/0054A61F2230/0067A61F2250/0068
    • A medical appliance is provided that includes a self-expanding stent; a sheath adapted to enclose the self-expanding stent in an interior space during deployment; and an external body comprising a bioactive agent attached to the self-expanding stent and adapted to lie outside the interior space of the sheath when the self-expanding stent is enclosed in the sheath. The medical appliance may be deployed in a lumen of a human body and the external body may release the bioactive agent. A method of producing a medical device is provided that includes attaching an external body to a stent and coupling the stent to a delivery arrangement. The external body includes a bioactive agent. A medical device is provided that includes a tissue scaffold; a sheath adapted to enclose the tissue scaffold in an interior space during deployment; and an external body comprising endothelial cells attached to the tissue scaffold and adapted to lie outside the interior space of the sheath when the tissue scaffold is enclosed in the sheath.
    • 提供了包括自扩张支架的医疗器具; 适于在展开期间将自扩张支架包围在内部空间中的护套; 以及包括附着在自膨胀支架上的生物活性剂的外部本体,并且当所述自扩张支架被包封在所述护套中时适于位于所述护套的内部空间外部。 医疗器具可以部署在人体的内腔中,并且外部体可以释放生物活性剂。 提供了一种制造医疗装置的方法,其包括将外部主体附接到支架并将支架联接到输送装置。 外部身体包括生物活性剂。 提供了包括组织支架的医疗装置; 适于在展开期间将组织支架封闭在内部空间中的护套; 以及外部体,其包括附着在所述组织支架上的内皮细胞,并且当所述组织支架被包封在所述鞘中时,所述外部本体适于位于所述鞘的内部空间的外部。