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    • 4. 发明申请
    • ANXIETY DISORDER MONITORING
    • 安静的异常监视
    • US20100280336A1
    • 2010-11-04
    • US12751537
    • 2010-03-31
    • Jonathon E. GiftakisMark T. RisePaul H. Stypulkowski
    • Jonathon E. GiftakisMark T. RisePaul H. Stypulkowski
    • A61B5/00
    • A61B5/0476A61B5/1118A61B5/165A61B5/4803A61B5/6846A61B5/7267
    • An anxiety episode may be identified as being an anxiety event that is attributable to an anxiety disorder of a patient based on the patient activity associated with the anxiety episode. The patient activity may include, for example, patient motion, patient posture or voice activity. Detection of the activity component during an anxiety episode can help distinguish between a general anxiety state and an anxiety event that differs from the general anxiety state. Examples of anxiety events include, for example, an occurrence of a compulsion or a panic attack. The detected anxiety events can be used to evaluate an anxiety disorder of a patient, evaluate therapy programs implemented by a medical device to treat the anxiety disorder, or control therapy delivery. In some examples, a mood state transition is detected based on patient activity information and therapy delivery is controlled based on the detection of the mood state transition.
    • 基于与焦虑发作相关的患者活动,可能将焦虑事件确定为可归因于患者的焦虑症的焦虑事件。 患者活动可以包括例如患者运动,患者姿势或语音活动。 在焦虑症状期间检测活动成分可以帮助区分一般焦虑状态和与一般焦虑状态不同的焦虑事件。 焦虑事件的例子包括例如强迫或惊恐发作的发生。 检测到的焦虑事件可用于评估患者的焦虑症,评估由医疗装置实施的治疗程序以治疗焦虑症或控制治疗递送。 在一些示例中,基于患者活动信息检测情绪状态转换,并且基于心情状态转换的检测来控制治疗递送。
    • 7. 发明申请
    • SELECTING THERAPY CYCLE PARAMETERS BASED ON MONITORED BRAIN SIGNAL
    • 基于监测的脑信号选择治疗周期参数
    • US20110137371A1
    • 2011-06-09
    • US12843665
    • 2010-07-26
    • Jonathon E. GiftakisPaul H. Stypulkowski
    • Jonathon E. GiftakisPaul H. Stypulkowski
    • A61N1/36
    • A61N1/36139A61B5/0478A61B5/4094A61N1/37247G16H40/63
    • Bioelectrical brain signals may be monitored at one more regions of the brain of a patient by a medical device. The monitored bioelectrical signals may be used to select one or more therapy cycle parameters, e.g., on cycle duration and/or off cycle duration, for therapy delivered to treat a patient disorder. In one example, the off cycle duration of a therapy may be selected based on the washout period determined from sensed brain signals of the patient following delivery of therapy during an on cycle. In another example, the on cycle duration and/or off cycle duration of a therapy may be selected to maintain the value of one or more characteristics of a brain signal (e.g., cortical activity) of patient within a threshold range of a target value defined for the characteristic that is associated with effective treatment of the patient disorder.
    • 可以通过医疗装置在患者的脑的另外一个区域监测生物电脑信号。 监测的生物电信号可用于选择一种或多种治疗周期参数,例如循环持续时间和/或关闭循环持续时间,用于治疗递送用于治疗患者病症的治疗。 在一个实例中,治疗的关闭周期持续时间可以基于在开启周期期间递送治疗后患者的感测的脑信号所确定的清除时间来选择。 在另一个实例中,可以选择治疗的开启周期持续时间和/或关闭周期持续时间以将患者的脑信号的一个或多个特征值(例如,皮层活动)的值保持在定义的目标值的阈值范围内 与有效治疗患者障碍有关的特征。