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    • 8. 发明申请
    • Ultra-sensitive detection systems
    • 超敏感检测系统
    • US20050069916A1
    • 2005-03-31
    • US10825568
    • 2004-04-14
    • Brian ChaitDarin LatimerPaul LizardiEric KershnarJon MorrowMatthew RothMartin MattessichKevin McConnell
    • Brian ChaitDarin LatimerPaul LizardiEric KershnarJon MorrowMatthew RothMartin MattessichKevin McConnell
    • G01N27/62C07H21/02C07H21/04C07K1/04C07K1/107C07K1/13C07K7/00C07K7/06C07K7/08C12Q1/68G01N27/333G01N27/447G01N27/64G01N33/483G01N33/53G01N33/566G01N33/58G01N33/68
    • G01N33/6842C07K1/047C07K1/1077C07K1/13C07K7/06C07K7/08G01N33/6803
    • Disclosed are compositions and methods for sensitive detection of one or multiple analytes. In general, the methods involve the use of special label components, referred to as reporter signals, that can be associated with, incorporated into, or otherwise linked to the analytes. In some embodiments, the reporter signals can be altered such that the altered forms of different reporter signals can be distinguished from each other. In some embodiments, sets of reporter signals can be used where two or more of the reporter signals in a set have one or more common properties that allow the reporter signals having the common property to be distinguished and/or separated from other molecules lacking the common property. In other embodiments, sets of reporter signal/analyte conjugates can be used where two or more of the reporter signal/analyte conjugates in a set have one or more common properties that allow the reporter signal/analyte conjugates having the common property to be distinguished and/or separated form other molecules lacking the common property. Reporter signals can also be in conjunction with analytes (such as in mixtures of reporter signals and analytes), where no significant physical association between the reporter signals and analytes occurs; or alone, where no analyte is present.
    • 公开了用于敏感检测一种或多种分析物的组合物和方法。 通常,这些方法涉及使用称为报告信号的特殊标记成分,其可以与分析物相关联,并入或以其它方式连接到分析物上。 在一些实施方案中,可以改变报道信号,使得不同报道信号的改变形式可以彼此区分。 在一些实施方案中,可以使用一组报告信号,其中一组中的两个或更多个报告基因信号具有一个或多个共同性质,其允许具有共同性质的报道信号被区分和/或与其他分子不相同 属性。 在其它实施方案中,可以使用组的报告信号/分析物缀合物,其中组中的两个或多个报道信号/分析物缀合物具有一个或多个共同性质,其允许区分具有共同性质的报道信号/分析物缀合物, /或分离形成其他缺乏共同性质的分子。 记者信号也可以与分析物(例如报告信号和分析物的混合物)结合,其中报告信号和分析物之间不存在明显的物理结合; 或单独存在,其中不存在分析物。
    • 9. 发明授权
    • Pump system for a firefighting vehicle
    • 用于消防车的泵系统
    • US07874373B2
    • 2011-01-25
    • US11551096
    • 2006-10-19
    • Jon MorrowDave SteinbergerCorey VoigtTim Meilahn
    • Jon MorrowDave SteinbergerCorey VoigtTim Meilahn
    • A62C27/00
    • A62C27/00F04D1/06F04D13/14F04D15/0072
    • A firefighting vehicle having a dual pressure pump system includes a fluid supply, a first pump stage coupled to the fluid supply and configured to pump fluid at a first pressure, a second pump stage coupled to the first pump stage and configured to pump fluid at a second pressure, the second pressure being substantially different from the first pressure, a fluid manipulator; and a valving arrangement coupling the first pump stage and the second pump stage to the fluid manipulator, the valving arrangement being selectively adjustable between a first position forming a first fluid path and a second position forming a second fluid path, wherein the first fluid path provides the fluid to the fluid manipulator at a first output pressure and the second fluid path provides fluid to the fluid manipulator at a second output pressure.
    • 具有双重压力泵系统的消防车辆包括流体供应,联接到流体供应并被配置成在第一压力下泵送流体的第一泵级,耦合到第一泵级的第二泵级,并且构造成在 第二压力,第二压力基本上不同于第一压力,流体操纵器; 以及将所述第一泵级和所述第二泵级耦合到所述流体操纵器的阀装置,所述阀装置可选择性地在形成第一流体路径的第一位置和形成第二流体路径的第二位置之间调节,其中所述第一流体路径提供 在第一输出压力下以流体机械手的流体和第二流体路径在第二输出压力下向流体操纵器提供流体。