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1. 发明授权

US08616195B2 Nebuliser for the production of aerosolized medication 有权
标题翻译：喷雾器用于生产雾化药物
公开(公告)号：US08616195B2
公开(公告)日：2013-12-31
申请号：US10833932
申请日：2004-04-27
申请人： John S Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
发明人： John S Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
IPC分类号： A61M11/00 , B05B17/06
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebulizer to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebulizer and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebulizer.
摘要翻译：一种用于递送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气溶胶发生器，其中发生器将至少一部分药物雾化成气溶胶，气体通气入口允许气体进入雾化器并与气溶胶形成混合物，以及将气溶胶和气体的混合物输送到喷雾器的出口的通道。

2. 发明申请

US20050011514A1 Nebuliser for the production of aerosolized medication 有权
标题翻译：喷雾器用于生产雾化药物
公开(公告)号：US20050011514A1
公开(公告)日：2005-01-20
申请号：US10833932
申请日：2004-04-27
申请人： John Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
发明人： John Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
IPC分类号： A61M15/00 , A61M16/00
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebuliser to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebuliser and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebuliser.
摘要翻译：一种用于递送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气溶胶发生器，其中发生器将至少一部分药物雾化成气溶胶，气体通气入口允许气体进入雾化器并与气溶胶形成混合物，以及将气溶胶和气体的混合物输送到雾化器的出口的通道。

3. 发明申请

US20050217666A1 Methods and systems for operating an aerosol generator 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US20050217666A1
公开(公告)日：2005-10-06
申请号：US11090328
申请日：2005-03-24
申请人： James Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
发明人： James Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
IPC分类号： A61M11/00 , A61M16/00
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 μg to about 500 mg of a medicament. Additionally, an aerosolized medicament for the treatment of a pulmonary disease, where the medicament includes amikacin mixed with an aqueous solution having an adjusted pH from about 5.5 to about 6.3. The pH is adjusted by adding hydrochloric acid and sodium hydroxide to the aqueous solution.
摘要翻译：一种治疗患有肺部疾病的患者的方法，其中所述方法包括将一定剂量的雾化药物间歇地递送至与患者呼吸系统相连的通气机回路。另外，一种治疗患有肺部疾病的患者的方法，其中所述方法包括使患者脱离呼吸机，并向患者施用包含约100至500mg药物的雾化气雾剂。另外，一种用于治疗肺部疾病的雾化药物，其中药物包含与调节pH约5.5至约6.3的水溶液混合的阿米卡星。通过向水溶液中加入盐酸和氢氧化钠来调节pH。

4. 发明申请

US20080060641A1 METHODS AND SYSTEMS FOR OPERATING AN AEROSOL GENERATOR 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US20080060641A1
公开(公告)日：2008-03-13
申请号：US11928214
申请日：2007-10-30
申请人： NIALL SMITH , John Power , James Fink , Michael Klimowicz
发明人： NIALL SMITH , John Power , James Fink , Michael Klimowicz
IPC分类号： A61M16/10
CPC分类号： A61J1/065 , A61J2205/10 , A61J2205/60 , A61M15/00 , A61M15/0028 , A61M15/0031 , A61M15/0033 , A61M15/0085 , A61M16/024 , A61M16/04 , A61M16/06 , A61M16/08 , A61M2016/0021 , A61M2016/0024 , A61M2205/52 , A61M2205/6045 , A61M2205/6054 , A61M2205/6072 , A61M2205/8206 , A61M2205/8262 , A61M2209/082 , B05B17/0646 , B65D1/095 , B65D2203/00
摘要： A nebulized fluid, generated by vibrating an aerosolization element, is introduced into a breathing circuit during a certain interval of a patient's breathing cycle. In some embodiments, the fluid comprises an antibiotic that is selected to treat a pulmonary infection resulting from mechanical ventilation.
摘要翻译：通过振动雾化元件产生的雾化流体在患者呼吸周期的一定间隔期间被引入呼吸回路中。在一些实施方案中，流体包含选择用于治疗由机械通气引起的肺部感染的抗生素。

5. 发明申请

US20050172954A1 Methods and systems for operating an aerosol generator 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US20050172954A1
公开(公告)日：2005-08-11
申请号：US10996994
申请日：2004-11-23
申请人： Niall Smith , John Power , James Fink , Michael Klimowicz
发明人： Niall Smith , John Power , James Fink , Michael Klimowicz
IPC分类号： A61K9/12 , A61J1/06 , A61K47/04 , A61M15/00 , A61M16/00 , A61M16/04 , A61M16/06 , A61M16/08 , B05B15/00 , B05B17/06 , B65D1/09 , A61M11/00
CPC分类号： A61J1/065 , A61J2205/10 , A61J2205/60 , A61M15/00 , A61M15/0028 , A61M15/0031 , A61M15/0033 , A61M15/0085 , A61M16/024 , A61M16/04 , A61M16/06 , A61M16/08 , A61M2016/0021 , A61M2016/0024 , A61M2205/52 , A61M2205/6045 , A61M2205/6054 , A61M2205/6072 , A61M2205/8206 , A61M2205/8262 , A61M2209/082 , B05B17/0646 , B65D1/095 , B65D2203/00
摘要： A nebule comprising at least one identification marker or label can be coupled an aerosol generator. The identification marker can be sensed by a sensing device on the aerosol generator so as to identify the liquid in the nebule to the controller of the aerosol generator. The controller of the aerosol generator can control the aerosol generator based on the information read from the identification marker.
摘要翻译：包含至少一个识别标记物或标记物的星云可以与气溶胶发生器连接。识别标记可以由气溶胶发生器上的感测装置感测，以便识别烟雾中的液体到气溶胶发生器的控制器。气溶胶发生器的控制器可以基于从识别标记读取的信息来控制气溶胶发生器。

6. 发明申请

US20060007653A1 Data center cooling system 有权
公开(公告)号：US20060007653A1
公开(公告)日：2006-01-12
申请号：US11228950
申请日：2005-09-16
申请人： James Fink
发明人： James Fink
IPC分类号： H05K7/20
CPC分类号： H05K7/20745 , E04H5/02 , E04H2005/005 , H05K7/2079
摘要： A modular data center includes a plurality of racks, each of the racks having a front face and a back face, wherein the plurality of racks is arranged in a first row and a second row, such that the back faces of racks of the first row are facing the second row, and the back faces of the racks of the second row are facing the first row, a first end panel coupled between a first rack of the first row and a first rack of the second row, the first end panel having a bottom edge and a tope edge, a second end panel coupled between a second rack of the first row and a second rack of the second row, the second end panel having a top edge and a bottom edge, and a roof panel coupled between the top edge of the first panel and the top edge of the second panel.

7. 发明申请

US20070267010A1 Methods and systems for operating an aerosol generator 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US20070267010A1
公开(公告)日：2007-11-22
申请号：US11654212
申请日：2007-01-16
申请人： James Fink , John Power , Ehud Ivri , Kevin Corkery
发明人： James Fink , John Power , Ehud Ivri , Kevin Corkery
IPC分类号： A61M11/00
CPC分类号： A61M16/20 , A61M11/005 , A61M15/0085 , A61M16/08 , A61M16/0858 , A61M16/1065 , A61M16/201 , A61M16/208
摘要： A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 μg to about 500 mg of a medicament. Also a method of treating a patient with a pulmonary disease, the method comprising administering an aerosolized first medicament comprising amikacin to the patient and administering, systemically a second medicament comprising an antibiotic to the patient that also treats the pulmonary disease, wherein a resulting amikacin concentration in the lung and/or pulmonary system is therapeutically-effective, and an amount of the systemically administered antibiotics is reduced.
摘要翻译：一种治疗患有肺部疾病的患者的方法，其中所述方法包括将一定剂量的雾化药物间歇地递送至与患者呼吸系统相连的通气机回路。另外，一种治疗患有肺部疾病的患者的方法，其中所述方法包括使患者脱离呼吸机，并向患者施用包含约100至500mg药物的雾化气雾剂。还有一种治疗患有肺部疾病的患者的方法，该方法包括向患者施用包含阿米卡星的雾化的第一药物，并全身给予包含抗生素的第二药物，所述抗生素还可治疗肺部疾病，其中得到的阿米卡星浓度在肺和/或肺系统中是治疗有效的，并且减少了全身施用的抗生素的量。

8. 发明授权

US07201167B2 Method and composition for the treatment of lung surfactant deficiency or dysfunction 有权
标题翻译：用于治疗肺表面活性物质缺乏症或功能障碍的方法和组合物
公开(公告)号：US07201167B2
公开(公告)日：2007-04-10
申请号：US11080279
申请日：2005-03-14
申请人： James Fink , Yehuda Ivri
发明人： James Fink , Yehuda Ivri
IPC分类号： A61M15/00
CPC分类号： A61M11/005 , A61M15/0085 , A61M16/0666 , A61M16/08 , A61M16/0833 , A61M16/1055 , A61M16/1065 , A61M16/14 , A61M2016/0021 , A61M2016/0033 , A61M2205/7518
摘要： A method of treating a disease involving surfactant deficiency or dysfunction in a patient's lungs is disclosed comprising the steps of providing a liquid lung surfactant composition; aerosolizing the lung surfactant composition with a vibrating aperture-type aerosol generator to form a surfactant aerosol; and introducing the surfactant aerosol into the gas flow within a circuit of a pressure-assisted breathing system coupled to the patient's respiratory system, whereby a therapeutically effective amount of said surfactant is delivered to the patient's lungs. Apparatus is also disclosed that increases the efficiency of delivery of aerosolized medicaments such as aerosolized lung surfactant.
摘要翻译：公开了一种治疗涉及患者肺部表面活性物质缺乏或功能障碍的疾病的方法，包括提供液体肺表面活性剂组合物的步骤; 用振动孔型气溶胶发生器雾化肺表面活性剂组合物以形成表面活性剂气溶胶; 以及将表面活性剂气溶胶引入耦合到患者呼吸系统的压力辅助呼吸系统的回路内的气流中，由此将治疗有效量的所述表面活性剂递送至患者的肺。还公开了增加雾化药物如气雾化肺表面活性剂的递送效率的装置。

9. 发明申请

US20050229927A1 Ventilation systems and methods employing aerosol generators 有权
标题翻译：采用气溶胶发生器的通风系统和方法
公开(公告)号：US20050229927A1
公开(公告)日：2005-10-20
申请号：US10828765
申请日：2004-04-20
申请人： James Fink , Ehud Ivri
发明人： James Fink , Ehud Ivri
IPC分类号： A61M11/00 , A61M15/00 , A61M16/00 , A61M16/08
CPC分类号： A61M11/005 , A61M15/0085 , A61M16/08 , A61M16/0833
摘要： A pressure-assisted breathing system comprises a pressure-generating circuit for maintaining a positive pressure within the system, and a patient interface device coupled to a patient's respiratory system. A respiratory circuit is positioned between the pressure-generating circuit and the patient interface device and a nebulizer is coupled to the respiratory circuit.
摘要翻译：压力辅助呼吸系统包括用于在系统内保持正压力的压力产生电路以及耦合到患者呼吸系统的患者接口装置。呼吸回路位于压力产生电路和患者接口装置之间，并且雾化器耦合到呼吸回路。

10. 发明授权

US06859366B2 Data center cooling system 有权
标题翻译：数据中心冷却系统
公开(公告)号：US06859366B2
公开(公告)日：2005-02-22
申请号：US10391971
申请日：2003-03-19
申请人： James Fink
发明人： James Fink
IPC分类号： H05K7/20
CPC分类号： H05K7/20745 , E04H5/02 , E04H2005/005 , H05K7/2079
摘要： A cooling solution is provided for a modular data center. The modular data center includes a plurality of racks, each of the racks having a front face and a back face, wherein the plurality of racks is arranged in a first row and a second row, such that the back faces of racks of the first row are facing the second row, and the back faces of the racks of the second row are facing the first row, a first end panel coupled between a first rack of the first row and a first rack of the second row, the first end panel having a bottom edge and a tope edge, a second end panel coupled between a second rack of the first row and a second rack of the second row, the second end panel having a top edge and a bottom edge, and a roof panel coupled between the top edge of the first panel and the top edge of the second panel. Cooling equipment within at least one of the equipment racks draws hot air from between the rows of racks and delivers cooled air out of the front face of one of the racks.
摘要翻译：为模块化数据中心提供冷却解决方案。模块化数据中心包括多个机架，每个机架具有前表面和后表面，其中多个机架布置在第一行和第二行中，使得第一行的机架的背面面向第二排，并且第二排的齿条的背面面向第一排，第一端面板联接在第一排的第一齿条和第二排的第一齿条之间，第一端面板具有底部边缘和顶部边缘，第二端板，其联接在第一行的第二齿条和第二排的第二齿条之间，第二端面板具有顶部边缘和底部边缘，以及顶板，第一面板的顶边缘和第二面板的上边缘。至少一个设备架内的冷却设备从机架排之间吸取热空气，并将冷却的空气从其中一个机架的前表面输出。

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