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1. 发明授权

US08616195B2 Nebuliser for the production of aerosolized medication 有权
标题翻译：喷雾器用于生产雾化药物
公开(公告)号：US08616195B2
公开(公告)日：2013-12-31
申请号：US10833932
申请日：2004-04-27
申请人： John S Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
发明人： John S Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
IPC分类号： A61M11/00 , B05B17/06
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebulizer to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebulizer and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebulizer.
摘要翻译：一种用于递送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气溶胶发生器，其中发生器将至少一部分药物雾化成气溶胶，气体通气入口允许气体进入雾化器并与气溶胶形成混合物，以及将气溶胶和气体的混合物输送到喷雾器的出口的通道。

2. 发明申请

US20050011514A1 Nebuliser for the production of aerosolized medication 有权
标题翻译：喷雾器用于生产雾化药物
公开(公告)号：US20050011514A1
公开(公告)日：2005-01-20
申请号：US10833932
申请日：2004-04-27
申请人： John Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
发明人： John Power , Declan Moran , Donal Devery , Gavan O'Sullivan , James Fink , Niall Smith
IPC分类号： A61M15/00 , A61M16/00
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebuliser to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebuliser and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebuliser.
摘要翻译：一种用于递送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气溶胶发生器，其中发生器将至少一部分药物雾化成气溶胶，气体通气入口允许气体进入雾化器并与气溶胶形成混合物，以及将气溶胶和气体的混合物输送到雾化器的出口的通道。

3. 发明申请

US20050217666A1 Methods and systems for operating an aerosol generator 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US20050217666A1
公开(公告)日：2005-10-06
申请号：US11090328
申请日：2005-03-24
申请人： James Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
发明人： James Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
IPC分类号： A61M11/00 , A61M16/00
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 μg to about 500 mg of a medicament. Additionally, an aerosolized medicament for the treatment of a pulmonary disease, where the medicament includes amikacin mixed with an aqueous solution having an adjusted pH from about 5.5 to about 6.3. The pH is adjusted by adding hydrochloric acid and sodium hydroxide to the aqueous solution.
摘要翻译：一种治疗患有肺部疾病的患者的方法，其中所述方法包括将一定剂量的雾化药物间歇地递送至与患者呼吸系统相连的通气机回路。另外，一种治疗患有肺部疾病的患者的方法，其中所述方法包括使患者脱离呼吸机，并向患者施用包含约100至500mg药物的雾化气雾剂。另外，一种用于治疗肺部疾病的雾化药物，其中药物包含与调节pH约5.5至约6.3的水溶液混合的阿米卡星。通过向水溶液中加入盐酸和氢氧化钠来调节pH。

4. 发明授权

US08196573B2 Methods and systems for operating an aerosol generator 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US08196573B2
公开(公告)日：2012-06-12
申请号：US12018716
申请日：2008-01-23
申请人： James B. Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
发明人： James B. Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
IPC分类号： A61M11/00 , A61M11/06 , A61M16/10
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A system for intermittent delivery of an aerosolized medicament is disclosed. The system may include an aerosol generator, a controller and a conduit. The aerosol generator may be configured to aerosolize a medicament. The controller may be configured to receive physiological characteristic information about a patient, and control the aerosol generator based at least in part on the physiological characteristic information. The conduit may be configured to supply the aerosolized medicament to the patient's airway.
摘要翻译：公开了用于间歇递送雾化药物的系统。该系统可以包括气溶胶发生器，控制器和导管。气溶胶发生器可以构造成使药物雾化。控制器可以被配置为接收关于患者的生理特征信息，并且至少部分地基于生理特征信息来控制气溶胶发生器。导管可以被构造成将雾化的药物供应到患者的气道。

5. 发明申请

US20080142002A1 Methods and Systems for Operating an Aerosol Generator 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US20080142002A1
公开(公告)日：2008-06-19
申请号：US12018716
申请日：2008-01-23
申请人： James B. Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
发明人： James B. Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
IPC分类号： A61M11/00
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A system for intermittent delivery of an aerosolized medicament is disclosed. The system may include an aerosol generator, a controller and a conduit. The aerosol generator may be configured to aerosolize a medicament. The controller may be configured to receive physiological characteristic information about a patient, and control the aerosol generator based at least in part on the physiological characteristic information. The conduit may be configured to supply the aerosolized medicament to the patient's airway.
摘要翻译：公开了用于间歇递送雾化药物的系统。该系统可以包括气溶胶发生器，控制器和导管。气溶胶发生器可以构造成使药物雾化。控制器可以被配置为接收关于患者的生理特征信息，并且至少部分地基于生理特征信息来控制气溶胶发生器。导管可以被构造成将雾化的药物供应到患者的气道。

6. 发明授权

US07971588B2 Methods and systems for operating an aerosol generator 有权
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：US07971588B2
公开(公告)日：2011-07-05
申请号：US11090328
申请日：2005-03-24
申请人： James B. Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
发明人： James B. Fink , John Power , Ehud Ivri , Niall Smith , Paul Dunne , Gavan O'Sullivan , Declan Moran , Keith Gibbons
IPC分类号： A61M16/00 , B05B11/00
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 μg to about 500 mg of a medicament. Additionally, an aerosolized medicament for the treatment of a pulmonary disease, where the medicament includes amikacin mixed with an aqueous solution having an adjusted pH from about 5.5 to about 6.3. The pH is adjusted by adding hydrochloric acid and sodium hydroxide to the aqueous solution.
摘要翻译：一种治疗患有肺部疾病的患者的方法，其中所述方法包括将一定剂量的雾化药物间歇地递送至与患者呼吸系统相连的通气机回路。另外，一种治疗患有肺部疾病的患者的方法，其中所述方法包括使患者脱离呼吸机，并向患者施用包含约100μg至约500mg药物的雾化气雾剂。另外，一种用于治疗肺部疾病的雾化药物，其中药物包含与调节pH约5.5至约6.3的水溶液混合的阿米卡星。通过向水溶液中加入盐酸和氢氧化钠来调节pH。

7. 发明申请

US20100126502A1 SELF-SEALING T-PIECE AND VALVED T-PIECE 审中-公开
标题翻译：自密封T型和阀门T型
公开(公告)号：US20100126502A1
公开(公告)日：2010-05-27
申请号：US11990587
申请日：2006-08-21
申请人： James B. Fink , Gavan O'Sullivan , Paul Dunne , Declan Moran , John Power , Niall Smith
发明人： James B. Fink , Gavan O'Sullivan , Paul Dunne , Declan Moran , John Power , Niall Smith
IPC分类号： A61M11/00
CPC分类号： A61M16/0833 , A61M11/00 , A61M15/009 , A61M16/0057 , A61M16/08 , A61M16/0875 , A61M16/14 , A61M16/20
摘要： Apparatus (500) and components for coupling fluid or gas conducting elements, such as apparatus and components for connecting a nebulizer (501) with a gas flow system. In particular, the apparatus (500) and components are useful for connecting, in a gas-tight and quick release manner, a nebulizer (501) to a pressure-assisted breathing system, such as a mechanical ventilator or a continuous positive airway pressure (“CPAP”) system.
摘要翻译：用于耦合流体或气体传导元件的装置（500）和用于将雾化器（501）与气体流动系统连接的装置和部件。特别地，装置（500）和部件可用于以气密和快速释放的方式将雾化器（501）连接到诸如机械呼吸机或持续正气道压力的压力辅助呼吸系统（501） “CPAP”）系统。

8. 发明授权

US09339838B2 Aerosol generator assembly 有权
标题翻译：气溶胶发生器总成
公开(公告)号：US09339838B2
公开(公告)日：2016-05-17
申请号：US13697517
申请日：2011-05-10
申请人： Declan Moran , Gavan O'Sullivan
发明人： Declan Moran , Gavan O'Sullivan
IPC分类号： A61M15/00 , A61M11/00 , B05B17/06 , B05B17/04 , B05B17/00 , A61M15/02
CPC分类号： B05B17/0676 , A61M11/005 , A61M15/0085 , A61M15/025 , A61M2202/0468 , B05B17/0646
摘要： An aerosol generator assembly comprising a vibratable piezo ceramic body (2) having first and second opposing sides, an aperture (o) defined in the vibratable body and extending through the body from the first side to the second side and having a layer of electrical contact material on each side of the vibratable body, the vibratable body being vibratable by application of an electrical signal thereto; a vibratable member (1) with pores defined therein, the vibratable member mounted across the aperture; and an electrical contact material free-zone (4) is provided on at least one side of the body about the aperture, characterized in that the electrical contact material free-zone and the vibratable member are dimensioned so that the vibratable member is mountable directly onto the vibratable body on top thereof within the electrical contact material free-zone such that a gap area free of electrode contact material is formed between the terminating edge of the electrical contact material and the periphery of the vibratable member.
摘要翻译：一种气溶胶发生器组件，包括具有第一和第二相对侧面的可振动压电陶瓷体（2），限定在可振动体中的孔（o），并且从第一侧延伸到第二侧并且具有电接触层材料在可振动体的每一侧上，可振动体通过向其施加电信号而可振动; 具有限定在其中的孔的可振动构件（1），所述可振动构件穿过所述孔安装; 并且在所述主体的至少一侧围绕所述孔提供电接触材料自由区（4），其特征在于，所述电接触材料自由区和所述可振动构件的尺寸被设计成使得所述可振动构件可直接安装到在电接触材料自由区的顶部上的可振动体，使得在电接触材料的终端边缘和可振动构件的周边之间形成没有电极接触材料的间隙区域。

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