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1. 发明授权

US07482455B2 Chemical compounds 失效
标题翻译：化合物
公开(公告)号：US07482455B2
公开(公告)日：2009-01-27
申请号：US10530986
申请日：2003-10-15
申请人： Joelle L. Burgess , James F. Callahan , Toshihiro Hamajima , Satoru Ida , Ichiro Mori , Jun Tang
发明人： Joelle L. Burgess , James F. Callahan , Toshihiro Hamajima , Satoru Ida , Ichiro Mori , Jun Tang
IPC分类号： C07D215/38
CPC分类号： C07D401/12 , C07D215/54 , C07D405/12
摘要： 3-carboxy quinoline derivatives, which are useful as YAK3 inhibitors are described herein. The described invention also includes methods of making such 3-carboxy quinoline derivatives as well as methods of using the same in the treatment of diseases mediated by inappropriate YAK3 activity.
摘要翻译：本文描述了可用作YAK3抑制剂的3-羧基喹啉衍生物。所述的发明还包括制备这种3-羧基喹啉衍生物的方法以及用于治疗由不适当的YAK3活性介导的疾病的方法。

2. 发明申请

US20060106058A1 Chemical compounds 失效
公开(公告)号：US20060106058A1
公开(公告)日：2006-05-18
申请号：US10530986
申请日：2003-10-15
申请人： Joelle Burgess , James Callahan , Toshihiro Hamajima , Satoru Ida , Ichiro Mori , Jun Tang
发明人： Joelle Burgess , James Callahan , Toshihiro Hamajima , Satoru Ida , Ichiro Mori , Jun Tang
IPC分类号： A61K31/4709 , C07D215/38 , A61K31/47 , C07D405/02 , C07D403/02
CPC分类号： C07D401/12 , C07D215/54 , C07D405/12
摘要： 3-carboxy quinoline derivatives, which are useful as YAK3 inhibitors are described herein. The described invention also includes methods of making such 3-carboxy quinoline derivatives as well as methods of using the same in the treatment of diseases mediated by inappropriate YAK3 activity.

3. 发明授权

US07495102B2 Azaindole inhibitors of aurora kinases 有权
标题翻译：极光激酶的阿片苷抑制剂
公开(公告)号：US07495102B2
公开(公告)日：2009-02-24
申请号：US11855183
申请日：2007-09-14
申请人： Martha A. Sarpong , Nicholas D. Adams , Jeffrey Michael Axten , Amita M. Chaudhari , Dashyant Dhanak , Toshihiro Hamajima , Kenneth Allen Newlander , Cynthia A. Parrish , Jerry Leroy Adams , Domingos J. Silva , Jun Tang
发明人： Martha A. Sarpong , Nicholas D. Adams , Jeffrey Michael Axten , Amita M. Chaudhari , Dashyant Dhanak , Toshihiro Hamajima , Kenneth Allen Newlander , Cynthia A. Parrish , Jerry Leroy Adams , Domingos J. Silva , Jun Tang
IPC分类号： C07D453/02
CPC分类号： C07D471/04
摘要： The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.
摘要翻译：本发明涉及由式（I）表示的化合物及其药学上可接受的盐。本发明的化合物抑制Aurora激酶，使其特别适用于治疗许多疾病，包括实体瘤癌症和血液癌症。

4. 发明申请

US20100016307A1 NOVEL COMPOUNDS 审中-公开
标题翻译：新型化合物
公开(公告)号：US20100016307A1
公开(公告)日：2010-01-21
申请号：US12446762
申请日：2007-10-24
申请人： Toshihiro Hamajima , Hiroko Nakamura , Jun Tang
发明人： Toshihiro Hamajima , Hiroko Nakamura , Jun Tang
IPC分类号： A61K31/5377 , C07D471/02 , C07D413/14 , A61K31/437
CPC分类号： C07D471/04
摘要： The present invention relates to compounds of formula (I): and processes for preparing them, compositions containing them and their use in treating diseases relating to inappropriate c-Met activity.
摘要翻译：本发明涉及式（I）化合物及其制备方法，含有它们的组合物及其在治疗与不适当的c-Met活性有关的疾病中的用途。

5. 发明申请

US20080081808A1 AZAINDOLE INHIBITORS OF AURORA KINASES 有权
公开(公告)号：US20080081808A1
公开(公告)日：2008-04-03
申请号：US11855183
申请日：2007-09-14
申请人： Martha Sarpong , Nicholas Adams , Jeffrey Axten , Amita Chaudhari , Dashyant Dhanak , Toshihiro Hamajima , Kenneth Newlander , Cynthia Parrish , Jerry Adams , Domingos Silva , Jun Tang
发明人： Martha Sarpong , Nicholas Adams , Jeffrey Axten , Amita Chaudhari , Dashyant Dhanak , Toshihiro Hamajima , Kenneth Newlander , Cynthia Parrish , Jerry Adams , Domingos Silva , Jun Tang
IPC分类号： A61K31/437 , A61K31/4545 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/54 , A61P35/00 , C07D471/04
CPC分类号： C07D471/04
摘要： The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.

6. 发明申请

US20090018156A1 Pyrrolo [2,3,B] Pyridine Derivatives Useful As RAF Kinase Inhibitors 审中-公开
标题翻译：吡咯并[2,3，B]吡啶衍生物可用作RAF激酶抑制剂
公开(公告)号：US20090018156A1
公开(公告)日：2009-01-15
申请号：US12162811
申请日：2007-01-31
申请人： Jun Tang , Masato Nakano , Toshihiro Hamajima
发明人： Jun Tang , Masato Nakano , Toshihiro Hamajima
IPC分类号： A61K31/437 , C07D471/04 , A61P35/00
CPC分类号： C07D471/04
摘要： The present invention provides pyrrolo pyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.
摘要翻译：本发明提供了吡咯吡啶化合物，含有它们的组合物，以及制备方法及其作为药剂的用途。

7. 发明申请

US20120302534A1 DERIVATIVES OF BETULIN 审中-公开
标题翻译：贝母的衍生物
公开(公告)号：US20120302534A1
公开(公告)日：2012-11-29
申请号：US13577452
申请日：2011-02-09
申请人： Daxin Gao , Nianhe Han , Zhimin Jin , Fangxian Ning , Jun Tang , Yongyong Wu , Heping Yang
发明人： Daxin Gao , Nianhe Han , Zhimin Jin , Fangxian Ning , Jun Tang , Yongyong Wu , Heping Yang
IPC分类号： A61K31/568 , A61P31/18 , A61K31/58 , C07J53/00
CPC分类号： A61K31/50 , A61K31/56 , C07C225/14 , C07C233/76 , C07C235/78 , C07C275/30 , C07C311/04 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2603/52 , C07D205/04 , C07D213/40 , C07D231/12 , C07D295/185 , C07D295/26 , C07D333/20
摘要： The present invention relates to a compound characterized by the following Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, X, and Y are as described herein. Compounds of the present invention are useful for the treatment of HIV-1.
摘要翻译：本发明涉及以下式I表征的化合物或其药学上可接受的盐，其中R 1，R 2，R 3，X和Y如本文所述。本发明的化合物可用于治疗HIV-1。

8. 发明授权

US07940764B2 Method and system for processing multicast packets 有权
标题翻译：处理组播数据包的方法和系统
公开(公告)号：US07940764B2
公开(公告)日：2011-05-10
申请号：US10567001
申请日：2004-08-12
申请人： Yongxiang Han , Wei Shao , Jian Dou , Hang Yuan , Jun Tang
发明人： Yongxiang Han , Wei Shao , Jian Dou , Hang Yuan , Jun Tang
IPC分类号： H04L12/56
CPC分类号： H04L49/201 , H04L12/18
摘要： Provided are a method, system, and program for processing multicast packets. A multicast packet is received to transmit to destination addresses. A payload of the multicast packet is written to at least one packet entry in a packet memory. Headers are generated for the destination addresses and at least one descriptor is generated addressing the at least one packet entry in the packet memory including the payload to transmit to the destination addresses. For each destination address, at least one indicator is generated including information on the generated header for the destination address and the at least one descriptor, wherein indicators for the destination addresses address the at least one descriptor.
摘要翻译：提供了一种用于处理组播数据包的方法，系统和程序。接收到组播数据包以发送到目的地址。组播分组的有效载荷被写入分组存储器中的至少一个分组条目。针对目的地地址生成标题，并且生成至少一个描述符，寻址包含有效载荷的分组存储器中的至少一个分组条目以发送到目的地址。对于每个目的地地址，生成至少一个指示符，包括关于目的地地址的所生成的报头和至少一个描述符的信息，其中目的地地址的指示符寻址至少一个描述符。

9. 发明授权

US07272011B2 Computer enclosure with rotatable cover mounting assembly 失效
标题翻译：具有可旋转盖安装组件的电脑外壳
公开(公告)号：US07272011B2
公开(公告)日：2007-09-18
申请号：US11288854
申请日：2005-11-29
申请人： Yun-Lung Chen , Jun Tang , Jian Hu
发明人： Yun-Lung Chen , Jun Tang , Jian Hu
IPC分类号： H05K7/16
CPC分类号： G06F1/181
摘要： A mounting assembly for computer cover includes a chassis having a rearwall, a cover mounted to the chassis, a first connecting bar and second connecting bar movably mounted on the rearwall of the chassis and a driving member mounted on the chassis. The cover has two opposite sidewalls. A protrusion extends from each of the sidewalls. Each of the two connecting bars forms a stopping portion for engaging with the protrusion. A driving portion is provided on the driving member for urging the two connecting bars to move. The driving portion of the driving member drives the two connecting bars to urge the stopping portions to disengage from the protrusions when the driving member is driven.
摘要翻译：用于计算机盖的安装组件包括具有后壁的底盘，安装到底盘的盖，可移动地安装在底盘的后壁上的第一连接杆和第二连接杆以及安装在底盘上的驱动构件。盖子有两个相对的侧壁。突起从每个侧壁延伸。两个连接杆中的每一个形成用于与突起接合的止动部分。驱动部件设置在驱动部件上，用于推动两个连杆移动。当驱动构件被驱动时，驱动构件的驱动部分驱动两个连接杆，以迫使止动部分从突起脱离。

10. 发明申请

US20070019377A1 Mounting apparatus for data storage device 失效
标题翻译：数据存储装置用安装装置
公开(公告)号：US20070019377A1
公开(公告)日：2007-01-25
申请号：US11317273
申请日：2005-12-23
申请人： Yun-Lung Chen , Jun Tang
发明人： Yun-Lung Chen , Jun Tang
IPC分类号： G06F1/16
CPC分类号： G06F1/187
摘要： A data storage device assembly includes a data storage device having two sidewalls, each sidewall having a first positioning post; a supporting bracket having two sidewalls, one of the sidewalls defining a guiding slot for locating the first positioning post; a driving member movably attached to the supporting bracket, the driving member having a sliding post; a pivoting member pivotally located between the driving member and the supporting bracket, the pivoting member defining a sliding slot for the sliding post to slide therein, and having a stopping block for locating the first positioning post; and a first elastic component for urging the driving member to move towards an original position. When the driving member is pushed, the sliding post of the driving member slides in the sliding slot to urge the pivoting member to rotate, thereby causing the first positioning post to disengage from the stopping block.
摘要翻译：数据存储装置组件包括具有两个侧壁的数据存储装置，每个侧壁具有第一定位柱; 具有两个侧壁的支撑托架，所述侧壁中的一个限定用于定位所述第一定位柱的引导槽; 驱动构件，其可移动地附接到所述支撑托架，所述驱动构件具有滑动柱; 枢转地位于所述驱动构件和所述支撑托架之间的枢转构件，所述枢转构件限定用于所述滑动杆在其中滑动的滑动槽，并且具有用于定位所述第一定位柱的止动块; 以及用于推动所述驱动构件朝向原始位置移动的第一弹性部件。当驱动构件被推动时，驱动构件的滑动柱在滑动槽中滑动以促使枢转构件旋转，从而使第一定位柱与止动块脱离。

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