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1. 发明申请

US20120202286A1 rbLIF PROTEIN FOR USE IN EMBRYONIC STEM CELL CULTURES 审中-公开
标题翻译： rbLIF蛋白用于胚胎干细胞培养
公开(公告)号：US20120202286A1
公开(公告)日：2012-08-09
申请号：US13451268
申请日：2012-04-19
申请人： Jie Xu , Jerry Yang , Xiuchun Tian , Fuliang Du , Yinghong Ma
发明人： Jie Xu , Jerry Yang , Xiuchun Tian , Fuliang Du , Yinghong Ma
IPC分类号： C12N5/0735 , C12N5/02
CPC分类号： C07K14/5415 , C12N2501/235
摘要： Provided herein methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell on a rabbit feeder cell layer, wherein the rabbit feeder layer expresses a leukemia inhibitory factor (LIF) protein. Also provided are methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell in a culture medium comprising rabbit leukemia inhibitory factor (rbLIF) protein. Also provided are polynucleotide and amino acid sequences of a rabbit leukemia inhibitory factor protein (rbLIF).
摘要翻译：本发明提供将胚胎干细胞培养物维持在未分化状态的方法，其中所述方法包括在兔饲养细胞层上培养胚胎干细胞，其中所述兔饲养层表达白血病抑制因子（LIF）蛋白。还提供了将胚胎干细胞培养物维持在未分化状态的方法，其中所述方法包括在包含兔白血病抑制因子（rbLIF）蛋白的培养基中培养胚胎干细胞。还提供了兔白血病抑制因子蛋白（rbLIF）的多核苷酸和氨基酸序列。

2. 发明申请

US20100227403A1 rbLIF PROTEIN FOR USE IN EMBRYONIC STEM CELL CULTURES 审中-公开
标题翻译： rbLIF蛋白用于胚胎干细胞培养
公开(公告)号：US20100227403A1
公开(公告)日：2010-09-09
申请号：US12637660
申请日：2009-12-14
申请人： Jie Xu , Jerry Yang , Xiuchun Tian , Fuliang Du , Yinghong Ma
发明人： Jie Xu , Jerry Yang , Xiuchun Tian , Fuliang Du , Yinghong Ma
IPC分类号： C12N5/0735 , C07K14/00 , C07H21/04
CPC分类号： C07K14/5415 , C12N2501/235
摘要： Provided herein methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell on a rabbit feeder cell layer, wherein the rabbit feeder layer expresses a leukemia inhibitory factor (LIF) protein. Also provided are methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell in a culture medium comprising rabbit leukemia inhibitory factor (rbLIF) protein. Also provided are polynucleotide and amino acid sequences of a rabbit leukemia inhibitory factor protein (rbLIF).
摘要翻译：本发明提供将胚胎干细胞培养物维持在未分化状态的方法，其中所述方法包括在兔饲养细胞层上培养胚胎干细胞，其中所述兔饲养层表达白血病抑制因子（LIF）蛋白。还提供了将胚胎干细胞培养物维持在未分化状态的方法，其中所述方法包括在包含兔白血病抑制因子（rbLIF）蛋白的培养基中培养胚胎干细胞。还提供了兔白血病抑制因子蛋白（rbLIF）的多核苷酸和氨基酸序列。

3. 发明授权

US08586369B2 Ion channel-forming peptides 有权
标题翻译：离子通道形成肽
公开(公告)号：US08586369B2
公开(公告)日：2013-11-19
申请号：US12668178
申请日：2008-07-09
申请人： Jerry Yang , Steven Blake , Michael Mayer
发明人： Jerry Yang , Steven Blake , Michael Mayer
IPC分类号： G01N33/00
CPC分类号： G01N33/5438
摘要： The invention pertains generally to novel compositions and methods for constructing chemically sensitive ion channels. The compositions and methods include, for example, novel gramicidin A derivatives and their use in constructing novel ion channels for use as biosensors.
摘要翻译：本发明一般涉及用于构建化学敏感离子通道的新型组合物和方法。组合物和方法包括例如新型短杆菌肽A衍生物及其在构建用作生物传感器的新型离子通道中的用途。

4. 发明申请

US20120302603A1 AMYLOID BINDING AGENTS 有权
标题翻译： AMYLOID绑定代理
公开(公告)号：US20120302603A1
公开(公告)日：2012-11-29
申请号：US13515239
申请日：2010-12-10
申请人： Jerry Yang , Emmanuel A. Theodorakis
发明人： Jerry Yang , Emmanuel A. Theodorakis
IPC分类号： C07C255/43 , G01N21/64 , A61P25/28 , A61K31/277 , A61K31/451 , G01N33/566 , C07D295/155
CPC分类号： G01N33/6896 , C07C255/42 , C07C255/43 , C07D295/13 , C07D295/155 , C07D317/24 , G01N2333/4703
摘要： There are provided compounds and methods for the detection and treatment of amyloid deposits and diseases and disorders characterized by amyloid deposits including Alzheimer's disease and related amyloid-based neurodegenerative disorders.
摘要翻译：提供了用于检测和治疗淀粉样蛋白沉积物和以淀粉样蛋白沉积物为特征的疾病和病症的化合物和方法，包括阿尔茨海默氏病和相关淀粉样蛋白的神经变性疾病。

5. 发明授权

US08575359B2 Acid-sensitive linkers for drug delivery 有权
标题翻译：用于药物输送的酸敏感接头
公开(公告)号：US08575359B2
公开(公告)日：2013-11-05
申请号：US12295858
申请日：2007-04-04
申请人： Jerry Yang , Seong Deok Kong , Alice Luong , Stephen Howell
发明人： Jerry Yang , Seong Deok Kong , Alice Luong , Stephen Howell
IPC分类号： C07D233/00 , C07D233/02 , C07D233/54 , C07D233/60 , C07H15/24
CPC分类号： C07D233/68 , C07D233/60
摘要： The invention is in general directed to acid-sensitive linkers, and methods of use thereof, such as, for example, in drug delivery methods.
摘要翻译：本发明一般涉及酸敏感连接体及其使用方法，例如药物递送方法。

6. 发明申请

US20070163150A1 Insole board for high-heel shoe 审中-公开
标题翻译：高跟鞋鞋垫
公开(公告)号：US20070163150A1
公开(公告)日：2007-07-19
申请号：US11331282
申请日：2006-01-13
申请人： Jerry Yang
发明人： Jerry Yang
IPC分类号： A43B21/06 , A43B23/00
CPC分类号： A43B13/41 , A43B7/141 , A43B17/00 , A43B21/22 , A43B21/24 , B29D35/142
摘要： An insole board for high-heel shoe includes a board member, a plastic molded member and a rigid supporting member embedded in the plastic molded member. The board member has a forefoot portion, a midfoot portion and a heel portion. The midfoot portion and said heel portion of the board member are split into an upper layer and a lower layer to form a space to enclose the plastic molded member and the rigid supporting member. The plastic molded member is shaped in such a way that a flexline and an arched surface are formed on the surface of the board member. The rigid supporting member and the plastic molded member are formed and enclosed in the space of the board member by one step molding process.
摘要翻译：用于高跟鞋的鞋垫板包括板构件，塑料模制构件和嵌入在塑料模制构件中的刚性支撑构件。板构件具有前脚部分，中脚部分和脚后跟部分。板构件的中脚部分和所述脚跟部分被分成上层和下层以形成用于封闭塑料模制构件和刚性支撑构件的空间。塑料模制构件的形状使得在板构件的表面上形成挠曲线和拱形表面。刚性支撑构件和塑料模制构件通过一步模制工艺形成并封闭在板构件的空间中。

7. 发明授权

US06447841B1 Plastic pigments for durable ink jet paper 失效
标题翻译：用于耐用喷墨纸的塑料颜料
公开(公告)号：US06447841B1
公开(公告)日：2002-09-10
申请号：US09323901
申请日：1999-06-02
申请人： Jeanlynn Mets , Yaoliang Hong , Mike Koenig , Hiroshi Tomimasu , Jerry Yang
发明人： Jeanlynn Mets , Yaoliang Hong , Mike Koenig , Hiroshi Tomimasu , Jerry Yang
IPC分类号： B05D138
CPC分类号： B41M5/52 , B41M5/506 , B41M5/5227 , B41M5/5254 , B41M5/5281 , B41M7/0054
摘要： The invention relates to ink jet printing and a process for ink jet printing wherein a coating is formed on an ink receiving layer containing a plastic pigment. The coating is fused into a durable coating which is water-resistant, has some lightfastness, is scratch resistant and can be used in indoor and outdoor environments.
摘要翻译：本发明涉及喷墨印刷和喷墨印刷方法，其中在含有塑料颜料的油墨接收层上形成涂层。涂层熔化成耐水涂层，具有耐光性，耐划伤性，可用于室内和室外环境。

8. 发明申请

US20130157924A1 REDUCING TRANSMISSION OF SEXUALLY TRANSMITTED INFECTIONS 审中-公开
标题翻译：减少传染性传染性感染
公开(公告)号：US20130157924A1
公开(公告)日：2013-06-20
申请号：US13643026
申请日：2011-04-22
申请人： Stephen Dewhurst , Bradley Nilsson , Joanna Olsen , Jerry Yang
发明人： Stephen Dewhurst , Bradley Nilsson , Joanna Olsen , Jerry Yang
IPC分类号： A61K31/428 , A61K47/48 , A61K45/06
CPC分类号： A61K31/428 , A61K45/06 , A61K47/55 , A61K47/64
摘要： Described herein are compositions and methods for treating or preventing a sexually transmitted infection in a subject.
摘要翻译：本文描述了用于治疗或预防受试者中性传播感染的组合物和方法。

9. 发明申请

US20130048499A1 CONTROLLING TRANSLOCATION THROUGH NANOPORES WITH FLUID WALL 有权
标题翻译：通过流体管道通过纳米管控制转移
公开(公告)号：US20130048499A1
公开(公告)日：2013-02-28
申请号：US13400472
申请日：2012-02-20
申请人： Michael Mayer , Erik Yusko , Jerry Yang
发明人： Michael Mayer , Erik Yusko , Jerry Yang
IPC分类号： G01N27/26 , B82Y30/00
CPC分类号： G01N33/48721 , B82Y30/00 , C12Q1/6869 , G01N15/1209 , G01N2015/0038 , C12Q2563/131 , C12Q2565/631
摘要： Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid lipid walls. The fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.
摘要翻译：当在Coulter原理上运行的装置中的纳米孔连接液体隔室设置有流体脂质壁时，实现了纳米颗粒的改进的分辨率和检测。流体脂质壁由脂质双层制成，优选包括脂质锚定的移动配体作为脂质双层的一部分。通过改变脂质双层中的移动配体的性质和浓度，提供脂质的多功能涂层。

10. 发明申请

US20110046020A1 NOVEL ION CHANNEL-FORMING PEPTIDES 有权
标题翻译：新型离子通道肽
公开(公告)号：US20110046020A1
公开(公告)日：2011-02-24
申请号：US12668178
申请日：2008-07-09
申请人： Jerry Yang , Steven Blake , Michael Mayer
发明人： Jerry Yang , Steven Blake , Michael Mayer
IPC分类号： C40B60/00 , C07K2/00 , C07K7/66 , C12Q1/42 , C12M1/34
CPC分类号： G01N33/5438
摘要： The invention pertains generally to novel compositions and methods for constructing chemically sensitive ion channels. The compositions and methods include, for example, novel gramicidin A derivatives and their use in constructing novel ion channels for use as biosensors.
摘要翻译：本发明一般涉及用于构建化学敏感离子通道的新型组合物和方法。组合物和方法包括例如新型短杆菌肽A衍生物及其在构建用作生物传感器的新型离子通道中的用途。

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