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1. 发明授权

US08355547B2 Ultrasonic imaging apparatus with adaptable spatial image combination 有权
标题翻译：具有适应性空间图像组合的超声成像设备
公开(公告)号：US08355547B2
公开(公告)日：2013-01-15
申请号：US10525132
申请日：2003-08-05
申请人： Jean-Michel Lagrange , Claude Cohen-Bacrie , Claire Levrier , Nicolas Villain , Robert R. Entrekin
发明人： Jean-Michel Lagrange , Claude Cohen-Bacrie , Claire Levrier , Nicolas Villain , Robert R. Entrekin
IPC分类号： G06K9/00
CPC分类号： G01S15/8995 , G01S7/52077
摘要： An ultrasonic imaging apparatus using a method for combining CMB images of the same object including a step of seeking representative contours CNT of an interface on the images to be combined IM,[I], IM[J] is disclosed. The step is intended to define interest areas IA[I], IA[J] in the vicinity of the representative contours. The method also includes analyzing the interest areas IA[I], IA[J] being intended to allocate weights W[I], W[J] to the points on the interest areas IA[I], IA[J] and to the points corresponding to the interest areas IA[I], IA[J] on the various images. The method also includes constructing a combination image IMC, a point on the combination image IMC corresponding to a point on at least one interest area IA being obtained from a weighting of the corresponding points on the images to be combined IM[I], IM[J] according to the weights W[I], W[J] allocated in the analysis step ANA.
摘要翻译：公开了一种使用组合相同对象的CMB图像的方法的超声波成像装置，包括在待组合的图像IM，[I]，IM [J]上的接口的代表性轮廓CNT的步骤。该步骤旨在定义在代表性轮廓附近的兴趣区域IA [I]，IA [J]。该方法还包括分析兴趣区域IA [I]，IA [J]旨在将权重W [I]，W [J]分配给兴趣区域IA [I]，IA [J]上的点，以及对应于各个图像上的兴趣区域IA [I]，IA [J]的点。该方法还包括构成组合图像IMC，对应于要组合的图像上的对应点的加权获得的至少一个感兴趣区域IA上的点上的组合图像IMC上的点，IM [I]，IM [ J]根据在分析步骤ANA中分配的权重W [I]，W [J]。

2. 发明授权

US07361144B2 Ultrasound imaging system with a high lateral resolution 失效
标题翻译：具有高横向分辨率的超声成像系统
公开(公告)号：US07361144B2
公开(公告)日：2008-04-22
申请号：US10512492
申请日：2003-04-22
申请人： Claire Levrier , Claude Cohen-Bacrie , Nicholas Villain , Jean-Michel Lagrange , Robert R. Entrekin
发明人： Claire Levrier , Claude Cohen-Bacrie , Nicholas Villain , Jean-Michel Lagrange , Robert R. Entrekin
IPC分类号： A61B8/00
CPC分类号： G01S7/52049 , G01S15/8977 , G01S15/8995
摘要： The invention relates to an ultrasound imaging system for forming an echographic image of a medium, which system includes a set [REC] of transducer elements [EL] which are operative in a transmission mode and in a reception mode for ultrasound waves, construction means [REB] for constructing echographic signals on the basis of signals [S[1] . . . S[N]] received on the transducer elements [EL], display means [DIS] which are coupled to the construction means [REB] in order to display an image of the medium formed by means of the echographic signals. The construction means [REB] are such that in so-called exclusion zones, in which a coherent reflector is detected and which are determined by determination means [DET], the reception delays [D] are estimated in a manner [INT] other than that [CORR] used for the other zones. The calculation [CAL] of echographic signals is then carried out on the basis of the estimated delays [D[Z],Di[Z}}. The invention enables a correction of phase aberrations and nevertheless offers an excellent lateral resolution, notably in the case of point coherent reflectors.
摘要翻译：本发明涉及一种用于形成介质的回波图像的超声波成像系统，该系统包括以传输模式和超声波接收模式操作的换能器元件[EL]的组[REC]，构造装置[ REB]，用于根据信号[S [1]构建回波信号。。。 S [N]]接收到传感器元件[EL]上，显示装置[DIS]，它们耦合到构造装置[REB]，以便显示通过回波信号形成的介质的图像。构造装置[REB]使得在所谓的排除区域中，其中检测到相干反射器并且由确定装置[DET]确定，所述接收延迟[D]以除[ [CORR]用于其他区域。然后基于估计的延迟[D [Z]，Di [Z}}进行回波信号的计算[CAL]。本发明能够校正相位差，并且提供优异的横向分辨率，特别是在点相干反射器的情况下。

3. 发明授权

US08208697B2 Method and apparatus for automatically developing a high performance classifier for producing medically meaningful descriptors in medical diagnosis imaging 有权
标题翻译：用于自动开发用于在医学诊断成像中产生医学上有意义的描述符的高性能分类器的方法和装置
公开(公告)号：US08208697B2
公开(公告)日：2012-06-26
申请号：US11721999
申请日：2005-12-13
申请人： James David Schaffer , Walid Ali , Larry J. Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicholas Villain , Robert R. Entrekin
发明人： James David Schaffer , Walid Ali , Larry J. Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicholas Villain , Robert R. Entrekin
IPC分类号： G06K9/36
CPC分类号： G06K9/6217
摘要： A method for determining the presence or absence of malignant features in medical images, wherein a plurality of base comparison or training images of various types of lesions taken of actual patient is examined by one or more image reading experts to create a first database array. Low-level features of each of the lesions in the same plurality of base comparisons or training images are determined using one or more image processing algorithms to obtain a second database array set. The first and second database array set are combined to create a training database array set which is input to a learning system that discovers/learns a classifier that maps from a subset of the low-level features to the expert's evaluation in the first database array set. The classifier is used to determine the presence of a particular mid-level feature in an image of lesion in a patient based solely on the image.
摘要翻译：一种用于确定医学图像中恶性特征的存在或不存在的方法，其中由一个或多个图像读取专家检查由实际患者取得的各种类型的损伤的多个基础比较或训练图像以创建第一数据库阵列。使用一个或多个图像处理算法确定相同多个基本比较或训练图像中的每个病变的低级特征以获得第二数据库阵列集。组合第一和第二数据库阵列组以创建训练数据库阵列集合，其被输入到发现/学习从低级特征的子集映射到第一数据库阵列集合中的专家评估的分类器的学习系统。分类器用于仅基于图像来确定患者的病变图像中特定中级特征的存在。

4. 发明授权

US06117081A Method for correcting blurring of spatially compounded ultrasonic diagnostic images 失效
标题翻译：用于校正空间复合超声诊断图像模糊的方法
公开(公告)号：US06117081A
公开(公告)日：2000-09-12
申请号：US335060
申请日：1999-06-17
申请人： James R. Jago , Robert R. Entrekin
发明人： James R. Jago , Robert R. Entrekin
IPC分类号： A61B8/14 , A61B8/00 , G01S7/52 , G01S15/89 , G06T1/00 , G06T3/00 , G06T7/00 , G06T7/60
CPC分类号： G01S7/52085 , G01S15/8913 , G01S15/8995 , G01S7/52025 , G01S7/5205 , G01S7/52057 , G01S7/52065 , A61B8/00 , G01S7/52023 , G01S7/52034 , G01S7/52038 , G01S7/5206
摘要： An ultrasonic imaging method is described in which component ultrasonic images which are to be spatially compounded are corrected for misregistration prior to compounding. The component images may be registered to a reference image or registered to form intermediate compound images which are then registered and compounded. The misregistration may be sensed by calculating a similarity or difference metric for a region of interest of the image frames being registered, or on the basis of reference lines acquired for the purpose of registering images.
摘要翻译：描述了一种超声成像方法，其中将要进行空间复合的分量超声波图像在混合之前被校正用于重合。分量图像可以被注册到参考图像或者被注册以形成中间化合物图像，然后将其注册和复合。可以通过计算正在注册的图像帧的感兴趣区域的相似度或差异度量，或者基于为了注册图像而获取的参考线来感测重新排列。

5. 发明授权

US4503861A Fetal heartbeat doppler transducer 失效
标题翻译：胎心跳多普勒换能器
公开(公告)号：US4503861A
公开(公告)日：1985-03-12
申请号：US500061
申请日：1983-06-01
申请人： Robert R. Entrekin
发明人： Robert R. Entrekin
IPC分类号： A61B8/02 , G10K11/30 , A61B10/00
CPC分类号： A61B8/02 , A61B8/0866 , G10K11/30
摘要： A doppler transducer which is particularly well adapted for use in fetal heartbeat measurements is comprised of a piston type transducer with a pair of lenses, which together provide both a divergent acoustic pattern and a flat surface for good acoustic coupling between the transducer and the mother's abdomen.
摘要翻译：特别适用于胎儿心跳测量的多普勒换能器包括具有一对透镜的活塞式换能器，其一起提供发散声学图形和平坦表面，用于在换能器和母体腹部之间良好的声耦合。

6. 发明授权

US06468216B1 Ultrasonic diagnostic imaging of the coronary arteries 有权
标题翻译：冠状动脉超声诊断成像
公开(公告)号：US06468216B1
公开(公告)日：2002-10-22
申请号：US09645872
申请日：2000-08-24
申请人： Jeffry E. Powers , Michalakis Averkiou , Matthew Bruce , Danny M. Skyba , Robert R. Entrekin , John D. Fraser , Clifford R. Cooley , Brent Stephen Robinson , David N. Roundhill , Gary Allen Schwartz , Patrick René Pesque
发明人： Jeffry E. Powers , Michalakis Averkiou , Matthew Bruce , Danny M. Skyba , Robert R. Entrekin , John D. Fraser , Clifford R. Cooley , Brent Stephen Robinson , David N. Roundhill , Gary Allen Schwartz , Patrick René Pesque
IPC分类号： A61B800
CPC分类号： A61B8/483 , A61B8/06 , A61B8/0883 , A61B8/0891 , A61B8/4472 , A61B8/481 , A61B8/543 , G01S7/52025 , G01S7/52074 , G01S7/5208 , G01S7/52095 , G01S15/8918 , G01S15/8925 , G01S15/894 , G01S15/8963 , G01S15/8979 , G01S15/8993 , G10K11/341 , Y10S128/916
摘要： An ultrasonic imaging method and apparatus are described for imaging the coronary arteries of the heart. The vascular system is infused with an ultrasonic contrast agent. A volumetric region of the heart wall including a coronary artery is three dimensionally scanned. A projection image of the volumetric region is produced from the scanning, providing a two dimensional contrast image of the coronary artery with the appearance of an angiogram. Preferably the coronary artery signals are segmented from contrast signals emanating from the myocardium and the heart blood pool so that the coronary arteries are clearly highlighted and distinct in the ultrasonic angiogram.
摘要翻译：描述了用于对心脏的冠状动脉成像的超声成像方法和装置。血管系统注入超声造影剂。包括冠状动脉的心壁的体积区域被三维扫描。从扫描产生体积区域的投影图像，提供冠状动脉的二维造影图像和血管造影图像的外观。优选地，冠状动脉信号从从心肌和心脏血池发出的对比信号分段，使得冠状动脉在超声波血管造影中被清楚地突出显示和不同。

7. 发明授权

US06224552B1 Ultrasonic diagnostic imaging system with reduced spatial compounding seam artifacts 有权
标题翻译：超声波诊断成像系统具有减少的空间复合缝隙伪像
公开(公告)号：US06224552B1
公开(公告)日：2001-05-01
申请号：US09335157
申请日：1999-06-17
申请人： James R. Jago , Daniel C. Schmiesing , Robert R. Entrekin
发明人： James R. Jago , Daniel C. Schmiesing , Robert R. Entrekin
IPC分类号： A61B800
CPC分类号： A61B8/00 , G01S7/52023 , G01S7/52025 , G01S7/52034 , G01S7/52038 , G01S7/5205 , G01S7/52057 , G01S7/5206 , G01S7/52065 , G01S7/52085 , G01S15/8913 , G01S15/8995
摘要： An ultrasonic diagnostic imaging system produces spatially compounded images by combining component frames acquired from different look directions. Different regions of the spatially compounded images are formed by different numbers of overlapping component frames. Seam artifacts at the boundaries of the regions are reduced by processing the component frames to maintain a common signal and noise characteristic, varying the transmit pulse amplitude or the receiver gain, spatially aligning component frames at the boundaries, or weighting scan lines less heavily at the seam boundaries.
摘要翻译：超声诊断成像系统通过组合从不同外观方向获得的组件框架产生空间复合图像。空间复合图像的不同区域由不同数量的重叠分量帧形成。通过处理分量帧来减少区域边界处的缝隙伪影，以保持共同的信号和噪声特性，改变发射脉冲幅度或接收机增益，在边界处空间对齐分量帧，或者在接缝边界。

8. 发明授权

US06682484B1 Compression plate for diagnostic breast imaging 失效
标题翻译：压缩板用于诊断乳腺成像
公开(公告)号：US06682484B1
公开(公告)日：2004-01-27
申请号：US10194766
申请日：2002-07-12
申请人： Robert R. Entrekin , Nicholas D. Change, III
发明人： Robert R. Entrekin , Nicholas D. Change, III
IPC分类号： A61B800
CPC分类号： A61B8/0825
摘要： A breast imaging system is described which includes compression plates for retaining a breast during an examination. One of compression plates is formed by a polymeric membrane stretched under tension to provide a rigid but compliant retention surface which is substantially acoustically transparent for the conduct of a sonographic examination. The polymeric membrane may also be substantially radiographically transparent for the conduct of a mammographic examination. The thickness of the membrane is chosen to be a function of one-half of the wavelength of the ultrasonic frequency used for the sonographic examination so as to be substantially transparent to ultrasonic energy at that frequency.
摘要翻译：描述了一种乳房成像系统，其包括用于在检查期间保持乳房的压缩板。压缩板中的一个由在张力下拉伸的聚合物膜形成，以提供刚性但顺从的保持表面，该保持表面对于进行超声波检查而言基本上是声学透明的。对于进行乳房X线照相检查，聚合物膜也可以基本上是放射学透明的。膜的厚度选择为用于超声波检查的超声频率的波长的一半的函数，以便在该频率下对超声能量基本上是透明的。

9. 发明授权

US06623432B2 Ultrasonic diagnostic imaging transducer with hexagonal patches 失效
公开(公告)号：US06623432B2
公开(公告)日：2003-09-23
申请号：US09908294
申请日：2001-07-17
申请人： Jeffry E. Powers , Michalakis Averkiou , Matthew Bruce , Danny M. Skyba , Robert R. Entrekin , John D. Fraser , Clifford R. Cooley , Brent Stephen Robinson , David N. Roundhill , Gary Allen Schwartz , Patrick Rene' Pesque
发明人： Jeffry E. Powers , Michalakis Averkiou , Matthew Bruce , Danny M. Skyba , Robert R. Entrekin , John D. Fraser , Clifford R. Cooley , Brent Stephen Robinson , David N. Roundhill , Gary Allen Schwartz , Patrick Rene' Pesque
IPC分类号： A61B800
CPC分类号： A61B8/483 , A61B8/06 , A61B8/0883 , A61B8/0891 , A61B8/4472 , A61B8/481 , A61B8/543 , G01S7/52025 , G01S7/52074 , G01S7/5208 , G01S7/52095 , G01S15/8918 , G01S15/8925 , G01S15/894 , G01S15/8963 , G01S15/8979 , G01S15/8993 , G10K11/341 , Y10S128/916
摘要： An ultrasonic imaging method and apparatus are described for imaging the coronary arteries of the heart. The vascular system is infused with an ultrasonic contrast agent. A volumetric region of the heart wall including a coronary artery is three dimensionally scanned. A projection image of the volumetric region is produced from the scanning, providing a two dimensional contrast image of the coronary artery with the appearance of an angiogram. Preferably the coronary artery signals are segmented from contrast signals emanating from the myocardium and the heart blood pool so that the coronary arteries are clearly highlighted and distinct in the ultrasonic angiogram.

10. 发明授权

US5085220A Doppler flow sensing device and method for its use 失效
标题翻译：多普勒流感测装置及其使用方法
公开(公告)号：US5085220A
公开(公告)日：1992-02-04
申请号：US417525
申请日：1989-10-05
申请人： Bruce M. Nudell , Robert R. Entrekin , Robert Skidmore , Nicholas P. Luckman
发明人： Bruce M. Nudell , Robert R. Entrekin , Robert Skidmore , Nicholas P. Luckman
IPC分类号： A61B8/06 , G01F1/66 , G01P5/24
CPC分类号： A61B8/065 , G01F1/663 , G01P5/244
摘要： A device for sensing blood flow in a human aorta and a method for its use. The device includes two arrays, each array including one or more ultrasonic transducers for transmitting and/or receiving ultrasonic pulses. By appropriate weighting and phasing of the two ultrasonic arrays, a wide beam for insonifying the entire aorta, and a narrow beam for insonifying only a portion of the interior of the aorta, are produced. In addition, signals from the arrays can be processed to produce a signal indicating the direction to move the device so that the wide beam insonifies the entire aorta and the narrow beam insonifies only an interior portion of the aorta. The direction-finding array can be made from sensors arranged in a north-south-east-west pattern or as four sectors of an annulus.

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