专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5607400A Pre-fillable syringe and stopper assembly therefor 失效
标题翻译：预填充注射器和止动器组件
公开(公告)号：US5607400A
公开(公告)日：1997-03-04
申请号：US445130
申请日：1995-05-19
申请人： Jean-Claude Thibault , Jean-Pierre Grimard , Catherine F. Faure
发明人： Jean-Claude Thibault , Jean-Pierre Grimard , Catherine F. Faure
IPC分类号： A61M5/178 , A61M5/31 , A61M5/315 , A61M5/32
CPC分类号： A61M5/31513 , A61M2005/3121 , A61M2005/3131 , A61M2205/0222 , A61M2205/0238 , A61M5/3202
摘要： A pre-fillable hypodermic syringe is provided. The hypodermic syringe includes a syringe barrel having opposed proximal and distal ends and a drug-receiving chamber therebetween. The distal end of the syringe receives a needle cannula that is sealingly and protectively covered by a cap. The proximal end of the syringe is sealed by a stopper assembly. The stopper assembly includes a distal stopper that is positioned adjacent the drug pre-filled into the syringe barrel. The distal stopper is formed to exhibit acceptably low sliding forces without the presence of lubricants deleterious to the drug. The stopper assembly further includes a proximal stopper formed from a material that exhibits acceptable microbiological sealing. Because the proximal stopper is separated from the drug by the distal stopper the proximal stopper may be treated with any convenient lubricant, such as silicone oil. The distal stopper functions as a barrier between the drug and the lubricant such as silicone oil that is on or near the proximal stopper. The proximal stopper, on the other hand, provides the required microbiological sealing.
摘要翻译：提供预先填充的皮下注射器。皮下注射器包括具有相对的近端和远端的注射器筒和其间的药物接收室。注射器的远端接收密封地且由帽盖保护性地覆盖的针插管。注射器的近端由止动器组件密封。止动器组件包括远端止动器，该远端止动件邻近预先填充到注射器筒内的药物定位。远端止动器形成为显示可接受的低滑动力，而不存在对药物有害的润滑剂。止动器组件还包括由表现出可接受的微生物密封的材料形成的近端塞。由于近侧止动器通过远端止动件与药物分开，所以近端止动器可以用任何方便的润滑剂例如硅油处理。远侧止血器用作药物和润滑剂之间的屏障，例如在近端塞上或附近的硅油。另一方面，近端塞子提供所需的微生物密封。

2. 发明授权

US06969375B2 Sealed connection device for medical use of the luer lock type and syringe incorporating such a device 有权
标题翻译：用于鲁尔锁式医疗用途的密封连接装置和结合这种装置的注射器
公开(公告)号：US06969375B2
公开(公告)日：2005-11-29
申请号：US10296429
申请日：2001-05-23
申请人： Jean-Claude Thibault , Hubert Jansen , Jean-Pierre Grimard
发明人： Jean-Claude Thibault , Hubert Jansen , Jean-Pierre Grimard
IPC分类号： A61M5/32 , A61M5/34 , A61M5/31
CPC分类号： A61M5/344 , A61M5/3202 , A61M5/346
摘要： Luer lock type connection device for medical use having a nozzle in which an axial internal passage is formed. The nozzle includes a bearing connection surface and a proximal annular retention zone. The connection device also has a flange forming an axial open seat having a wall that includes a distal part with internal screw thread, and a transverse proximal part in which a central proximal retention opening is formed, and whose diameter is matched to that of the proximal annular zone of the nozzle. The proximal annular retention zone of the nozzle and/or the central proximal retention opening of the flange include a circular band or cord covered or treated with a roughening agent.
摘要翻译：用于医疗用途的鲁尔锁式连接装置具有其中形成有轴向内部通道的喷嘴。喷嘴包括轴承连接表面和近端环形保持区域。连接装置还具有形成轴向开口座的凸缘，其具有包括具有内螺纹的远侧部分的壁和横向近端部分，其中形成有中心近端保持开口，并且其直径与近端喷嘴的环形区域。喷嘴的近端环形保持区域和/或凸缘的中心近侧保持开口包括用粗糙剂覆盖或处理的圆形带或绳索。

3. 发明申请

US20050103666A1 Package for products to be sterlised with a high-temperature sterilising fluid 有权
标题翻译：用高温灭菌液灭菌的产品包装
公开(公告)号：US20050103666A1
公开(公告)日：2005-05-19
申请号：US10485930
申请日：2001-11-16
申请人： Jean-Pierre Grimard , Jean-Claude Thibault
发明人： Jean-Pierre Grimard , Jean-Claude Thibault
IPC分类号： B65D77/26 , A61J1/14 , A61L2/26 , B65D53/04 , B65D81/20 , A61L15/00
CPC分类号： A61L2/183 , A61L2/26 , A61L2202/181 , A61L2202/24 , A61M5/008
摘要： The invention concerns a plastic package, having a content capable of being sterilised at high temperature, said package comprising at least a fluid communication member (16) between the inside and the outside of said package consisting of at least a frame circumscribing an opening and an inner seal (18) closing the opening, and whereof the peripheral edge (18a, 22a) is continuously linked to said frame, said inner seal including, a selectively sealing material sheet whereof the cutoff threshold from outside inwards, stops contaminating particles and allows through the thermal sterilising fluid, said selectively sealing material being deformable in the plane of said sheet at said high temperature. The invention is characterised in that it comprises means compensating the planar deformation of the selectively sealing material sheet, when said inner seal (18) is in contact with the thermal sterilising fluid, said compensating means being designed to release at least part of the load in the direction opening the fluid communication member (16) applied on the frame as a result of said deformation.
摘要翻译：本发明涉及一种塑料包装，其具有能够在高温下灭菌的内容物，所述包装至少包括在所述包装的内部和外部之间的流体连通构件（16），该流体连通构件至少包括围绕开口的框架和封闭开口的内部密封件（18），并且周边边缘（18a，22a）连续地连接到所述框架，所述内部密封件包括选择性地密封材料片，其中从外侧进入的截止阈值停止污染颗粒，允许通过热灭菌流体，所述选择性密封材料可在所述高温下在所述片材的平面中变形。本发明的特征在于，当所述内部密封件（18）与热灭菌流体接触时，其包括补偿选择性密封材料片材的平面变形的装置，所述补偿装置设计成将至少部分负载释放作为所述变形的结果，打开施加在框架上的流体连通构件（16）的方向。

4. 发明授权

US6003702A Vial with resealable connector assembly having a membrane and a multi-configuration fluid access device 失效
标题翻译：具有可重复密封的连接器组件的样品瓶，其具有膜和多配置流体存取装置
公开(公告)号：US6003702A
公开(公告)日：1999-12-21
申请号：US534519
申请日：1995-09-27
申请人： Jean-Pierre Grimard , Jean-Claude Thibault
发明人： Jean-Pierre Grimard , Jean-Claude Thibault
IPC分类号： B65D51/18 , A61J1/00 , A61J1/20 , B65D47/24 , B65D47/30 , B65B1/06 , B65D39/00 , B65D45/30
CPC分类号： A61J1/2089 , B65D47/248 , A61J1/201 , A61J1/2037 , A61J1/2055 , A61J1/2072 , Y10S215/03
摘要： A resealable vial featuring a fluid access device having a membrane for selectively opening or sealing a fluid passageway between the bottle and the fluid access device. The vial includes a body disposed on said bottle. The fluid access device can be configured as a spike assembly, a needle assembly, or a luer lock assembly, and features a hollowed rod in sliding, fluid-tight relation to an orifice defined by the body. A membrane, preferably formed from an elastomeric material, is secured across both the orifice and the open top of the bottle, and may be retained between the top surface of the bottle and the body. The membrane preferably includes a central area sealing the orifice from the open top of the bottle, with one or more fluid passages defined on a portion of the membrane outside of the central area. A force exerted upon the hollowed rod deflects the membrane towards the interior of the vial, urging the membrane and fluid openings away from the body to open the fluid path between the bottle and the orifice. A sealing rib may be provided around the portion of the periphery of the recess for sealing contact between the central area of the membrane and the orifice.
摘要翻译：一种可重新密封的小瓶，其特征在于具有用于选择性地打开或密封瓶与流体存取装置之间的流体通道的膜的流体进入装置。小瓶包括设置在所述瓶子上的主体。流体通道装置可以被配置为尖钉组件，针组件或路厄锁定组件，并且具有与由主体限定的孔隙滑动，流体密封的中空杆。优选由弹性体材料形成的膜跨过瓶口的孔口和开口顶部固定，并且可以保持在瓶子的顶部表面和主体之间。膜优选地包括从孔的开口顶部密封孔口的中心区域，其中一个或多个流体通道限定在中心区域外部的膜的一部分上。施加在中空杆上的力使膜朝向小瓶的内部偏转，从而使膜和流体开口远离本体以打开瓶和孔之间的流体路径。密封肋可以围绕凹部的周边部分设置，用于密封膜的中心区域和孔口之间的接触。

5. 发明授权

US07100768B2 Package for products to be sterilized with a high-temperature sterilizing fluid 有权
标题翻译：用高温灭菌液灭菌的产品包装
公开(公告)号：US07100768B2
公开(公告)日：2006-09-05
申请号：US10485930
申请日：2001-11-16
申请人： Jean-Pierre Grimard , Jean-Claude Thibault
发明人： Jean-Pierre Grimard , Jean-Claude Thibault
IPC分类号： A61B17/06
CPC分类号： A61L2/183 , A61L2/26 , A61L2202/181 , A61L2202/24 , A61M5/008
摘要： The invention concerns a plastic package, having a content capable of being sterilised at high temperature, said package comprising at least a fluid communication member (16) between the inside and the outside of said package consisting of at least a frame circumscribing an opening and an inner seal (18) closing the opening, and whereof the peripheral edge (18a, 22a) continuously linked to said frame, said inner seal including, a selectively sealing material sheet whereof the cutoff threshold from outside inwards, stops contaminating particles and allows through the thermal sterilising fluid, said selectively sealing material being deformable in the plane of said sheet at said high temperature. The invention is characterised in that it comprises means compensating the planar deformation of the selectively sealing material sheet, when said inner seal (18) is in contact with the thermal sterilising fluid, said compensating means being designed to release at least part of the load in the direction opening the fluid communication member (16) applied on the frame as a result of said deformation.
摘要翻译：本发明涉及一种塑料包装，其具有能够在高温下灭菌的内容物，所述包装至少包括在所述包装的内部和外部之间的流体连通构件（16），该流体连通构件至少包括围绕开口的框架和封闭开口的内密封件（18），以及与所述框架连续连接的周边边缘（18a，22a），所述内密封件包括选择性密封材料片，其中从外侧进入的截止阈值停止污染颗粒，并允许通过热灭菌流体，所述选择性密封材料可在所述高温下在所述片材的平面中变形。本发明的特征在于，当所述内部密封件（18）与热灭菌流体接触时，其包括补偿选择性密封材料片材的平面变形的装置，所述补偿装置设计成将至少部分负载释放作为所述变形的结果，打开施加在框架上的流体连通构件（16）的方向。

6. 发明授权

US5613291A Method for providing a sterility seal in a medicinal storage bottle 失效
标题翻译：在药用储藏瓶中提供无菌密封的方法
公开(公告)号：US5613291A
公开(公告)日：1997-03-25
申请号：US377885
申请日：1995-01-25
申请人： Donald D. Solomon , Jean-Claude Thibault
发明人： Donald D. Solomon , Jean-Claude Thibault
IPC分类号： B65B7/28 , A61J1/00 , A61J1/14 , A61J1/20 , B65D41/02 , B65D53/06 , B23P25/00
CPC分类号： A61J1/2089 , A61J1/1412 , A61J1/18 , A61J1/1468 , A61J1/201 , Y10S604/905 , Y10T29/49885 , Y10T29/49982
摘要： A bottle having a sterility seal and a method for producing same are disclosed. The bottle, which can be configured to retain a medicament in powder or tablet form, features a protective cap configured to engage a transfer assembly associated with the bottle. The cap includes one or more raised ridges on an interior surface engageable with a portion of the transfer assembly. A band or layer configuration of a sealing material such as silicone is applied to the transfer assembly prior to insertion of the cap thereover. As the cap comes into surface contact with the sealing material, the ridges cause the material to "roll up" into a toroidal O-ring configuration, thereby forming a seal between the cap and the bottle adapted to the dimensional variations of those components. The seal, which is resilient, is able to withstand harsh handling treatment and pressure or temperature variations without separation from the cap or bottle, thereby providing a hermetic seal isolating the transfer assembly and, hence, the medicament from the outside environment.
摘要翻译：公开了一种具有无菌密封的瓶子及其制造方法。可以构造成保持粉末或片剂形式的药物的瓶具有构造成接合与瓶相关联的转运组件的保护帽。所述盖包括在内表面上与所述转移组件的一部分可接合的一个或多个凸脊。在其上插入盖之前，将诸如硅树脂的密封材料的带或层构造施加到转移组件。当盖与密封材料进行表面接触时，脊使材料“卷起”成环形O形环构型，从而在适于这些部件的尺寸变化的帽和瓶之间形成密封。具有弹性的密封件能够承受恶劣的处理处理和压力或温度变化，而不会与盖或瓶分离，从而提供将转印组件以及因此从外部环境分离的气密密封。

7. 发明授权

US06957745B2 Transfer set 有权
标题翻译：转移集
公开(公告)号：US06957745B2
公开(公告)日：2005-10-25
申请号：US10059497
申请日：2002-01-29
申请人： Jean-Claude Thibault , Hubert Jansen , Stephen Bint
发明人： Jean-Claude Thibault , Hubert Jansen , Stephen Bint
IPC分类号： A61J1/00 , A61J1/14 , A61J1/20 , B65D51/00 , B65D39/00 , B65D41/10 , B65D47/04
CPC分类号： A61J1/2096 , A61J1/1406 , A61J1/1412 , A61J1/201 , B65D51/002 , Y10S215/03
摘要： A transfer set for transferring fluids from a first container, such as a conventional vial, to a second container, such as a conventional syringe. The transfer set includes an integral tubular housing having a tubular collar surrounding the rim of the vial, a radial portion sealingly engaging the stopper in the vial, an integral tubular transfer member and an outer tubular portion surrounding at least the distal portion of the tubular transfer member, a piercing member within the tubular transfer member and a closure releasably retaining the distal end of the piercing member.
摘要翻译：用于将流体从诸如常规小瓶的第一容器传送到诸如常规注射器的第二容器的传送装置。传送组件包括整体管状壳体，其具有围绕小瓶边缘的管状套环，径向部分密封地接合瓶中的止动件，整体管状传送构件和至少围绕管状传送器的远端部分的外部管状部分构件，管状转移构件内的刺穿构件和可释放地保持穿孔构件的远端的封闭件。

8. 发明授权

US06681946B1 Resealable medical transfer set 有权
公开(公告)号：US06681946B1
公开(公告)日：2004-01-27
申请号：US09665859
申请日：2000-09-20
申请人： Hubert Jansen , Jean-Claude Thibault
发明人： Hubert Jansen , Jean-Claude Thibault
IPC分类号： B65D3900
CPC分类号： A61J1/1406 , A61J1/201 , A61J1/2096 , B65D51/002 , Y10S215/03
摘要： A transfer set for transferring fluid, including drugs, vaccines, medicaments, solutions and the like, between a first container, such as a conventional vial, and a second container, such as a conventional syringe having a unique multipurpose resealable member. The transfer set assembly includes an elastomeric tubular fluid transfer and resealable valve member preferably including an open end mounted on the pierceable closure or stopper of a vial and a generally closed distal end having a longitudinal slit and a piercing member is telescopically received within the fluid transfer valve member having a piercing end opposite the pierceable closure. The fluid transfer valve member is preferably formed of silicone and is surrounded by a generally tubular luer connector member having an open end mounted on the pierceable closure and a distal end having male luer threads. This assembly is enclosed within a cup-shaped closure and the assembly is retained to the first container or vial by a collar preferably secured to the vial by crimping. Upon removal of the cup-shaped closure, fluid communication between the vial and a second container, such as a syringe, is achieved by threading the luer connector of the syringe on the luer threads of the tubular luer connector member, which drives the tip through the slit of the elastomeric fluid transfer valve member against the distal end of the piercing member, driving the piercing end through the pierceable closure. In the preferred embodiment, the piercing member includes a generally longitudinal channel which establishes communication between the vial and the syringe through the tubular fluid transfer valve member.

9. 发明授权

US06209738B1 Transfer set for vials and medical containers 有权
标题翻译：转瓶套和医疗容器
公开(公告)号：US06209738B1
公开(公告)日：2001-04-03
申请号：US09420998
申请日：1999-10-20
申请人： Hubert Jansen , Jean-Claude Thibault
发明人： Hubert Jansen , Jean-Claude Thibault
IPC分类号： B65D3900
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2096 , B65D51/002 , Y10S215/03
摘要： A transfer set assembly for transferring fluids between a first container, such as a conventional medical vial, having a sealed open end and a second container such as a conventional IV infusion bag. The transfer set includes a collar having a proximate tubular end portion for securement to the container, a needle cannula and holder assembly, which is telescopically received in a distal tubular portion of the collar, and a closure including a tubular body portion having an open proximate end which is telescopically received over the needle cannula and holder assembly and the distal tubular portion of the collar, a closed distal end portion and an inner tubular portion which is integral with the closed distal end. The inner tubular portion includes a free end having spiral camming surfaces which mate with spiral camping surfaces on the inside surface of the tubular distal portion of the needle cannula holder. The tubular body portion of the closure includes lateral slots which receive projections on the collar and contiguous camming surface which extends toward the proximate open end of the closure. Rotation of the closure relative to the collar first drives the mating spiral camming surfaces of the closure and holder together, thereby driving the needle cannula and holder assembly axially to pierce the seal of the container. Continued rotation of the closure drives the projections on the collar against the contiguous angled camming surface, driving the closure from the collar and providing access to the needle cannula for transfer of fluids to a second container, such as an IV infusion bag.
摘要翻译：一种用于在具有密封开口端的第一容器（例如常规医用小瓶）和诸如常规IV输液袋的第二容器之间传送流体的转移组件。转移组件包括具有用于固定到容器的近端管状端部的套环，套管和保持器组件，其可伸缩地容纳在套环的远端管状部分中，以及封闭件，该封闭件包括管状本体部分，其可伸缩地容纳在针插管和保持器组件以及套环的远端管状部分，封闭的远端部分和与封闭的远端一体的内部管状部分。内部管状部分包括具有螺旋形凸轮表面的自由端，其与针管保持器的管状远端部分的内表面上的螺旋形露营表面配合。封闭件的管状主体部分包括横向狭槽，其接收套环上的凸起和朝向闭合件的近端开口端延伸的邻接凸轮表面。闭合件相对于套环的旋转首先将闭合件和保持器的配合的螺旋凸轮表面驱动到一起，从而轴向地驱动针插管和保持器组件以刺穿容器的密封。闭合件的继续旋转驱动套环上的凸起抵靠邻接的倾斜的凸轮表面，从套环驱动闭合件，并提供对针管的通路，以将流体传送到第二容器，例如IV输液袋。

10. 发明授权

US06904662B2 Method of sealing a cartridge or other medical container with a plastic closure 有权
标题翻译：用塑料盖封住药筒或其他医疗容器的方法
公开(公告)号：US06904662B2
公开(公告)日：2005-06-14
申请号：US09841371
申请日：2001-04-24
申请人： Jean-Claude Thibault , Hubert Jansen , Volker Niermann
发明人： Jean-Claude Thibault , Hubert Jansen , Volker Niermann
IPC分类号： A61J1/00 , A61J1/14 , A61J1/20 , B65B7/28 , B65D51/00 , B23P11/00
CPC分类号： A61J1/1406 , A61J1/201 , A61J1/2037 , A61J1/2041 , A61J1/2093 , A61J1/2096 , A61M2207/00 , B65B7/285 , B65D51/002 , Y10T29/4987 , Y10T29/49918 , Y10T29/49922 , Y10T29/49927
摘要： A method of sealing a cartridge having a barrel with a polymeric closure, wherein the polymeric closure includes a tubular collar portion and an integral radial portion, The method includes disposing the tubular collar portion over the radial rim portion of the barrel to surround the reduced diameter neck portion and incrementally rolling and radially deforming the tubular collar portion adjacent its free end into the reduced diameter neck portion with a crimping tool, wherein the polymeric closure is sufficiently malleable to permit radial deformation, yet sufficiently rigid and resistant to creep to retain its shape following deformation The crimping tool or tools include an inclined surface having a gradually decreasing angles of inclination which are driven against the tubular collar portion adjacent the free end and the cartridge assembly and crimping tool are relatively rotated.
摘要翻译：一种用聚合物封闭物密封具有筒体的盒的方法，其中所述聚合物封闭件包括管状套环部分和整体的径向部分。所述方法包括将所述管状套环部分设置在所述筒的径向边缘部分上以围绕所述缩小的直径颈部和逐渐地滚动，并且使用压接工具将管状套环部分邻近其自由端径向地变形成直径减小的颈部，其中聚合物封闭件具有足够的延展性以允许径向变形，但足够刚性并且抗蠕变以保持其形状随后变形压接工具或工具包括具有逐渐减小的倾斜角度的倾斜表面，其相对于与自由端相邻的管状套环部分被驱动，并且盒组件和压接工具相对旋转。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式