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1. 发明申请

US20180221573A1 Aseptic Connections For Drug Delivery Devices 审中-公开
公开(公告)号：US20180221573A1
公开(公告)日：2018-08-09
申请号：US15885404
申请日：2018-01-31
申请人： UNL Holdings LLC
发明人： Ian B. Hanson , Lawton Laurence , Antonio Ubach
IPC分类号： A61M5/162 , A61M5/142 , A61J1/14
CPC分类号： A61M5/162 , A61J1/1406 , A61J1/1412 , A61M5/14248 , A61M2205/18 , A61M2205/3317 , A61M2205/50 , A61M2205/581 , A61M2205/587 , A61M2207/00
摘要： Devices and methods for establishing aseptic connections between a drug container and a fluid pathway connection for a drug pump are provided. A fluid pathway connection includes a connection hub, a piercing member, a piercing member retainer, and a drug container. The drug container includes a cap, a pierceable seal, and a barrel. The piercing member is at least partially disposed in a sterile chamber defined by the connection hub, and the connection hub is configured to be connected to the drug container while maintaining an aseptic condition of a fluid pathway from the sterile chamber to an interior of the drug container.

2. 发明申请

US20180104149A1 CONTAINMENT AND TRANSFER DEVICE FOR HIGHLY ACTIVE OR SENSITIVE COMPOUNDS 审中-公开
公开(公告)号：US20180104149A1
公开(公告)日：2018-04-19
申请号：US15559963
申请日：2016-03-15
申请人： Leonard A. NOWAK , Merck Sharp & Dohme Corp.
发明人： LEONARD A. NOWAK
IPC分类号： A61J1/20 , A61J1/14 , A61J1/10 , F16K7/06 , F16L23/036 , F16L55/115 , F16B2/06 , F16B2/10
CPC分类号： A61J1/2048 , A61J1/10 , A61J1/1412 , A61J1/1468 , A61J1/1475 , A61M39/10 , A61M39/20 , A61M39/28 , F16B2/065 , F16B2/10 , F16B2/12 , F16K7/06 , F16L23/036 , F16L55/115 , F16L2201/44
摘要： A containment and transfer device for use with highly active or sensitive compounds, comprising a sleeve or a bag with one or more flexible walls, a first sanitary clamp, an endcap, a second sanitary clamp and a compression clamp. The sleeve or bag has a first end for connection to a container, and a second end for (a) connection to a storage or mixing vessel at the discharge location, or (b) connection to an endcap for transportation. The flexible walls surround and define an internal passageway in that permits compounds in the first end of the sleeve or bag to pass into the second end of the sleeve or bag. The compression clamp compresses the flexible walls of the sleeve or bag together to produce a barrier across the internal passageway, preventing the highly active or sensitive compound from flowing into the second end of the sleeve or bag during packing, transporting and discharging the device.

3. 发明授权

US09918902B2 Bottle for pharmacological and/or nutritional active substances with hermetic closure pierceable with a needle-free syringe and automatically resealable 有权
公开(公告)号：US09918902B2
公开(公告)日：2018-03-20
申请号：US14407701
申请日：2013-06-21
申请人： PAOLO GOBBI FRATTINI s.r.l.
发明人： Paolo Giuseppe Gobbi Frattini
IPC分类号： A61J1/22 , B65D51/00 , B65D51/20 , A61J1/14 , A61J1/20
CPC分类号： A61J1/22 , A61J1/1406 , A61J1/1412 , A61J1/1468 , A61J1/2003 , B65D51/002 , B65D51/20
摘要： A bottle for containing pharmacological and/or nutritional active substances is described. The bottle comprises a closing cap pierceable by the pressure exerted with the luer of a needle-free syringe. The closing cap is made as a single piece including a check valve and closing lips which can be opened by introducing a syringe luer and can be elastically closed back upon the extraction of the luer introduced, and a membrane which is pierceable and elastically resealable to hermetically close the inlet end of the check valve.

4. 发明申请

US20180055992A1 BAG FOR HOUSING INFUSION BAG/BOTTLE, USE OF THE SAME, AND METHOD FOR MANUFACTURING THE SAME 审中-公开
公开(公告)号：US20180055992A1
公开(公告)日：2018-03-01
申请号：US15554382
申请日：2016-04-22
申请人： PAL MEDICAL CO., LTD.
发明人： Keiichi ONO , Tsutomu UEDA
IPC分类号： A61M5/14 , A61J1/10 , A61J1/14 , B65D75/58
CPC分类号： A61M5/1409 , A61J1/10 , A61J1/14 , A61J1/1412 , A61J1/1462 , A61J1/16 , A61M5/00 , A61M5/1414 , B65D75/58
摘要： There is provided a bag for infusion bag/bottle, comprising a first end having a form of open end, and a second end having a form of close end, the second end being provided in opposed relation to the first end, wherein the first end is provided with a first sealing structure, and the second end is provided with a second sealing structure, and wherein the second end has a cutout opening or an incision.

5. 发明申请

US20180028762A1 Cap Assembly for a Medicament Delivery Device 审中-公开
公开(公告)号：US20180028762A1
公开(公告)日：2018-02-01
申请号：US15220547
申请日：2016-07-27
申请人： Carebay Europe Ltd.
发明人： Brian Maxfield
IPC分类号： A61M5/32 , B65D50/04 , A61J1/14
CPC分类号： A61M5/3202 , A61J1/1412 , A61M5/3204 , A61M2207/00 , B65D50/041 , B65D50/048
摘要： The present disclosure relates to a cap assembly (5) for a medicament delivery device, comprising: a cap (7) having a tubular body (7b) defining an axially extending distal opening (7c) and configured to be mounted to a proximal end of a medicament delivery device, wherein the cap (7) has a bottom structure (7e) defining a proximal end of the distal opening (7c), wherein the bottom structure (7e) has a cam structure (7f) provided inside the tubular body (7b), and wherein the tubular body (7b) has inner walls provided with radial recesses (7d), and an elongated squeeze member (9) configured to be received in the distal opening (7c) of the tubular body (7b), and having a longitudinally extending channel (9d) configured to receive a delivery member shield, and which squeeze member (9) has radial arms (9e) flexible in the radial direction and forming part of a wall of the channel (9d), wherein the squeeze member (9) has a proximal end face (9a) configured to cooperate with the cam structure (7f) of the cap (7), whereby axial displacement of the squeeze member (9) from a first position in which the proximal end face (9a) bears against the cam structure (7f) to a second position in which the squeeze member (9) is received further by the cap (7) causes rotation of the squeeze member (9) relative to the cap (7), wherein the radial arms (9e) are configured to engage with a respective radial recess (7d) of the tubular body (7b) in the first position of the squeeze member (9), and wherein the radial arms (9e) are configured to disengage from the respective radial recess when the squeeze member (9) is displaced from the first position to the second position and rotated, whereby the flexible radial arms (9e) are pressed into the channel (9d) by the inner walls of the tubular body (7b), reducing a cross-sectional area of the channel (9d).

6. 发明申请

US20180014997A1 Device for Transferring a Fluid Between a Storage Container and at Least One Further Container for Use 审中-公开
公开(公告)号：US20180014997A1
公开(公告)日：2018-01-18
申请号：US15546654
申请日：2016-01-22
申请人： BAYER PHARMA AKTIENGESELLCHAFT
发明人： Gero Eichelkraut , Tobias Festel , Frank Skaper , Martin Bayer , Christoph Merhold
IPC分类号： A61J1/20 , A61J1/14
CPC分类号： A61J1/2051 , A61J1/1412 , A61J1/201 , A61J1/2055 , A61J1/2082 , A61J1/2096
摘要： A device serves for transferring a fluid between a storage container and at least one further container for use. Said transfer device comprises a sealing section by means of which a main part of the transfer device sealingly rests on the storage container. A hollow-needle assembly comprises a hollow needle which can be moved between a retracted resting position and a deployed connecting position, the assembly, in the connecting position, providing a fluid connecting channel between the storage container and the transfer device. The hollow-needle assembly can be moved by means of a pressure actuating element. During said movement, the pressure actuating element is primarily connected to the sleeve of the hollow needle so as to be resistant to shear forces. A guiding device serves to axially guide the pressure actuating element on the main part. Said guiding device has at least one guiding pin. Said guiding pin slides in at least one associated guiding groove during movement. The guiding device is designed such that the movement of the hollow-needle assembly from the resting position to the connecting position is irreversible. In this way, the hollow needle can be moved from the resting position to the connecting position in an operationally safe manner.

7. 发明授权

US09867730B2 Tubing valve and uses thereof 有权
公开(公告)号：US09867730B2
公开(公告)日：2018-01-16
申请号：US14405494
申请日：2013-06-12
申请人： FlowSense Ltd.
发明人： Martin Clive Henry Jackson
IPC分类号： A61F5/44 , A61F5/451 , A61M39/00 , A61M39/26 , A61M39/10 , A61M39/12 , F16L37/40 , A61M5/162 , A61J1/10 , A61J1/14
CPC分类号： A61F5/4405 , A61F5/451 , A61J1/10 , A61J1/1412 , A61M5/162 , A61M39/10 , A61M39/12 , A61M39/26 , F16L37/40
摘要： A tubing valve is provided, including a valve body; a valve stem configured to be inserted into the valve body; and a valve tip configured to be inserted and fixed into the valve stem on its top part after it is positioned inside the valve body and to provide a holding position to a tube on its bottom side, wherein the tubing valve is opened upon pushing the valve tip and closed upon pulling said tube off the valve tip.

8. 发明申请

US20170368008A1 BOLUS DOSE OF HYDROXYCITRIC ACID WITH GLYCEROL 有权
公开(公告)号：US20170368008A1
公开(公告)日：2017-12-28
申请号：US15701107
申请日：2017-09-11
申请人： GLYKON TECHNOLOGIES GROUP, LLC
发明人： Dallas L. CLOUATRE , Daniel E. CLOUATRE , Brad J. DOUGLASS
IPC分类号： A61K31/194 , A61K45/06 , A61K36/74 , A61K36/42 , A61K31/216 , A61J1/14 , A61K31/00 , A61K9/14 , A61K9/00 , A61K47/10 , A61K36/185
CPC分类号： A61K31/194 , A61J1/1412 , A61K9/0053 , A61K9/0095 , A61K9/14 , A61K9/145 , A61K31/00 , A61K31/047 , A61K31/216 , A61K36/185 , A61K36/42 , A61K36/74 , A61K45/06 , A61K47/10 , A61K2300/00
摘要： A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of active delivered via two or three administrations (b.i.d. or t.i.d.) using current delivery modalities. The method reduces the rate of occurrence of common adverse events with hydroxycitric acid salts, and reduces the occurrence of reverse effects on diets high in fat and/or alcohol. The method improves the uptake of the active compound thereby reducing the dose required.

9. 发明申请

US20170339944A1 METHOD OF PRESERVING ORGANISMS AND APPARATUS THEREOF 审中-公开
公开(公告)号：US20170339944A1
公开(公告)日：2017-11-30
申请号：US15590026
申请日：2017-05-09
申请人： HUI-HSING YU
发明人： HUI-HSING YU
IPC分类号： A01N1/02 , A61M1/16 , A61J1/05 , A61M1/02 , A61J1/14
CPC分类号： A01N1/021 , A01N1/00 , A01N1/02 , A01N1/0242 , A01N1/0278 , A61J1/05 , A61J1/1412 , A61M1/0259 , A61M1/169
摘要： A simple, natural method of preserving organisms includes sealing biological blood or organisms in a shell filled with resin, curing the resin, and solidifying the shell for a long time to form amber. The biological blood or organisms can be preserved for a long time. Scholars of later generations may research the integrity of the biological blood or organisms of the present days. Otherwise, the biological blood or organisms may be of no researching meaning and purposes due to pollution or oxidation and dehydration. The organisms of the present days may be reconstructed after 100 years by using technologies of that time. Thus, the organisms being extinct due to pollution can be reconstructed. Diversities of organisms on the earth can be maintained. Precious genes of the organisms of the present days can be preserved for thousands years. It contributes greatly to the study of evolution of organisms.

10. 发明申请

US20170297781A1 VIAL CAP 审中-公开
公开(公告)号：US20170297781A1
公开(公告)日：2017-10-19
申请号：US15518150
申请日：2015-11-09
申请人： DAIKYO SEIKO, LTD.
发明人： Hideaki KAWAMURA
IPC分类号： B65D41/58 , B65D41/62 , A61J1/14
CPC分类号： B65D41/58 , A61J1/06 , A61J1/1412 , A61J1/1425 , B65D41/62 , B65D51/18
摘要： There is provided a vial cap with which, when there is a possibility that a cover which covers a stopper for a vial has come off and the stopper for the vial has been contaminated at a stage prior to use, the fact can easily be recognized. The vial cap is a resin vial cap (1) to be attached to a mouth portion (72) of a vial (70) to fix a stopper (74) fitted into the mouth portion (72) so that the stopper may not come off the mouth portion (72). The vial cap (1) is provided with a cap main body (8) that has an upper opening (6) formed therein and a cover (40) that covers the upper opening (6) of the cap main body (8). The cap main body (8) has a plurality of pin-receiving holes (10) formed therein, and the cover (40) has a plurality of fixing pins (46). Each pin-receiving hole (10) and a fixing pin (46) that is paired with the pin-receiving hole (10) are formed in complementary shapes. The plurality of fixing pins (46) of the cover (40) are accommodated in the plurality of pin-receiving holes (10) of the cap main body (8), and the cap main body (8) and the cover (40) are joined with the pin-receiving holes (10) and the fixing pins (46) engaged.

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