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1. 发明授权

US11172960B2 Apparatus and method for septal punch 有权
公开(公告)号：US11172960B2
公开(公告)日：2021-11-16
申请号：US17192329
申请日：2021-03-04
申请人： James S. Gammie , Philip J. Haarstad , David Blaeser , Ryan Bauer , Stephen Roller , Rachael Quinn , Chetan Pasrija , Edwin Hlavka
发明人： James S. Gammie , Philip J. Haarstad , David Blaeser , Ryan Bauer , Stephen Roller , Rachael Quinn , Chetan Pasrija , Edwin Hlavka
IPC分类号： A61B17/34 , A61B17/00
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.

2. 发明申请

US20060009800A1 Closure devices, related delivery methods, and related methods of use 有权
标题翻译：关闭装置，相关的运送方式和相关的使用方法
公开(公告)号：US20060009800A1
公开(公告)日：2006-01-12
申请号：US10934735
申请日：2004-09-07
申请人： Mark Christianson , Scott Olson , Edward Anderson , Philip Haarstad , Douglas Krone , Dennis Wahr , David Blaeser
发明人： Mark Christianson , Scott Olson , Edward Anderson , Philip Haarstad , Douglas Krone , Dennis Wahr , David Blaeser
IPC分类号： A61B17/08 , A61D1/00
CPC分类号： A61B17/0057 , A61B17/22032 , A61B17/221 , A61B90/39 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/2215 , A61F2002/011
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. A system for delivering the closure device includes side-by-side tubes. A device for retrieving a mis-deployed closure device includes a shaft portion and an expandable retrieval portion.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚用于输送封闭装置的系统包括并排管。用于检索错误展开的闭合装置的装置包括轴部分和可扩张的回缩部分。

3. 发明申请

US20110009801A1 DEVICES AND METHODS FOR TREATMENT OF OBESITY 有权
标题翻译：用于治疗肥胖的装置和方法
公开(公告)号：US20110009801A1
公开(公告)日：2011-01-13
申请号：US12677227
申请日：2008-09-12
申请人： David Blaeser , Dale Spencer
发明人： David Blaeser , Dale Spencer
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61B17/064 , A61B17/0644 , A61B2017/00818 , A61F2/04 , A61F2002/045
摘要： A device for isolating tissue in the digestive tract including a biocompatible portion having a surface sized to cover the tissue to be isolated and also includes a plurality of micro-anchors attached to the biocompatible portion and extending from the surface, the micro-anchors sized to penetrate the mucosa of the tissue. A method for isolating tissue in the digestive tract in which an isolation element is delivered to a desired location in the digestive system; the isolation element having fixed thereto a plurality of micro-anchors. The method also includes attaching the isolation element to tissue at the desired location by causing the micro-anchors to penetrate the mucosa of the tissue.
摘要翻译：一种用于分离消化道中的组织的装置，包括生物相容部分，其具有尺寸适于覆盖要分离的组织的表面，并且还包括附接到生物相容部分并从表面延伸的多个微锚，所述微锚尺寸为穿透组织的粘膜。一种用于分离消化道中的组织的方法，其中分离元件被递送到消化系统中的期望位置; 该隔离元件固定有多个微锚。该方法还包括通过使微锚定体穿透组织的粘膜而将隔离元件附接到期望位置处的组织。

4. 发明申请

US20060036284A1 PFO closure devices and related methods of use 有权
公开(公告)号：US20060036284A1
公开(公告)日：2006-02-16
申请号：US11249317
申请日：2005-10-14
申请人： David Blaeser , Peter Keith , Jerome Grudem , Scott Olson , Steven Hackett , Thomas Ressemann , Joel Phillips , Mark Christianson , Dennis Wahr
发明人： David Blaeser , Peter Keith , Jerome Grudem , Scott Olson , Steven Hackett , Thomas Ressemann , Joel Phillips , Mark Christianson , Dennis Wahr
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/00491 , A61B17/0057 , A61B17/0401 , A61B2017/00575 , A61B2017/00592 , A61B2017/00615 , A61B2017/0409 , A61B2017/0458 , A61B2017/0464 , A61B2017/0474 , A61B2017/0496 , A61B2017/22051
摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

5. 发明申请

US20050131447A1 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US20050131447A1
公开(公告)日：2005-06-16
申请号：US11034824
申请日：2005-01-14
申请人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
发明人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
IPC分类号： A61B17/00 , A61B17/12 , A61B17/22 , A61B19/00 , A61F2/06 , A61F2/82 , A61F2/84 , A61M25/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Prior to advancing a device across a stenosis to be treated, normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped. While blood flow is stopped, the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。抽真空组件包括限定具有近端和远端的抽空腔的细长管。近侧密封表面设置在管的近端部分上，并被构造成与引导导管的内腔形成密封。远端密封表面设置在管的远端部分上并构造成与血管形成密封。使用排气鞘组件治疗血管的方法包括通过引导导管将排空鞘组件推进到血管中。在将装置推进通过待治疗的狭窄之前，停止在狭窄附近的血管中的正常顺行血流。当血流停止时，狭窄处理。在血管内引起逆行血流，以便在处理进入抽真空鞘组件期间将栓塞物移走。

6. 发明申请

US20070066994A1 Closure devices, related delivery methods, and related methods of use 审中-公开
标题翻译：关闭装置，相关的运送方式和相关的使用方法
公开(公告)号：US20070066994A1
公开(公告)日：2007-03-22
申请号：US11522193
申请日：2006-09-16
申请人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
发明人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor preferably also includes a plurality of arms and preferably does not include a cover. Preferably, the elongate member has a first end fixedly connected to the left atrial anchor and a portion, proximal to the first end, passing through the right atrial anchor. Preferably, the elongate member is flexible.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚右心房锚优选地包括多个臂和附接到臂的盖。左心房锚固件优选地还包括多个臂，并且优选地不包括盖。优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的部分，穿过右心房锚。优选地，细长构件是柔性的。

7. 发明申请

US20060036282A1 Closure devices, related delivery methods and tools, and related methods of use 有权
公开(公告)号：US20060036282A1
公开(公告)日：2006-02-16
申请号：US11198325
申请日：2005-08-08
申请人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
发明人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2018/00214 , A61B2018/00273 , A61B2018/00351
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor also includes a plurality of arms and preferably does not include a cover. Preferably, the elongate member has a first end of fixedly connected to the left atrial anchor and a portion, proximal to the first end, releasably connected to the right atrial anchor. Preferably, the elongate member is flexible.

8. 发明申请

US20150374524A1 DEVICES AND METHODS FOR TREATMENT OF OBESITY 审中-公开
标题翻译：用于治疗肥胖的装置和方法
公开(公告)号：US20150374524A1
公开(公告)日：2015-12-31
申请号：US14847486
申请日：2015-09-08
申请人： David Blaeser , Dale Spencer
发明人： David Blaeser , Dale Spencer
IPC分类号： A61F5/00 , A61B17/064
CPC分类号： A61F5/0076 , A61B17/064 , A61B17/0644 , A61B2017/00818 , A61F2/04 , A61F2002/045
摘要： A device for isolating tissue in the digestive tract including a biocompatible portion having a surface sized to cover the tissue to be isolated and also includes a plurality of micro-anchors attached to the biocompatible portion and extending from the surface, the micro-anchors sized to penetrate the mucosa of the tissue. A method for isolating tissue in the digestive tract in which an isolation element is delivered to a desired location in the digestive system; the isolation element having fixed thereto a plurality of micro-anchors. The method also includes attaching the isolation element to tissue at the desired location by causing the micro-anchors to penetrate the mucosa of the tissue.
摘要翻译：一种用于分离消化道中的组织的装置，包括生物相容部分，其具有尺寸适于覆盖要分离的组织的表面，并且还包括附接到生物相容部分并从表面延伸的多个微锚，所述微锚尺寸为穿透组织的粘膜。一种用于分离消化道中的组织的方法，其中分离元件被递送到消化系统中的期望位置; 该隔离元件固定有多个微锚。该方法还包括通过使微锚定体穿透组织的粘膜而将隔离元件附接到期望位置处的组织。

9. 发明授权

US09155608B2 Devices and methods for treatment of obesity 有权
标题翻译：用于治疗肥胖的装置和方法
公开(公告)号：US09155608B2
公开(公告)日：2015-10-13
申请号：US12677227
申请日：2008-09-12
申请人： David Blaeser , Dale Spencer
发明人： David Blaeser , Dale Spencer
IPC分类号： A61F2/04 , A61B19/00 , A61F2/36 , A61B17/064 , A61F5/00 , A61B17/00
CPC分类号： A61F5/0076 , A61B17/064 , A61B17/0644 , A61B2017/00818 , A61F2/04 , A61F2002/045
摘要： A device for isolating tissue in the digestive tract including a biocompatible portion having a surface sized to cover the tissue to be isolated and also includes a plurality of micro-anchors attached to the biocompatible portion and extending from the surface, the micro-anchors sized to penetrate the mucosa of the tissue. A method for isolating tissue in the digestive tract in which an isolation element is delivered to a desired location in the digestive system; the isolation element having fixed thereto a plurality of micro-anchors. The method also includes attaching the isolation element to tissue at the desired location by causing the micro-anchors to penetrate the mucosa of the tissue.
摘要翻译：一种用于分离消化道中的组织的装置，包括生物相容部分，其具有尺寸适于覆盖要分离的组织的表面，并且还包括附接到生物相容部分并从表面延伸的多个微锚，所述微锚尺寸为穿透组织的粘膜。一种用于分离消化道中的组织的方法，其中分离元件被递送到消化系统中的期望位置; 该隔离元件固定有多个微锚。该方法还包括通过使微锚定体穿透组织的粘膜而将隔离元件附接到期望位置处的组织。

10. 发明申请

US20070016250A1 Closure devices, related delivery methods, and related methods of use 有权
标题翻译：关闭装置，相关的运送方式和相关的使用方法
公开(公告)号：US20070016250A1
公开(公告)日：2007-01-18
申请号：US11522158
申请日：2006-09-16
申请人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
发明人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor preferably also includes a plurality of arms and preferably, does not include a cover. Preferably, the elongate member has a first end fixedly connected to the left atrial anchor and a portion, proximal to the first end, passing through the right atrial anchor. Preferably, the elongate member is flexible.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚右心房锚优选地包括多个臂和附接到臂的盖。左心房锚优选地还包括多个臂，优选地不包括盖。优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的部分，穿过右心房锚。优选地，细长构件是柔性的。

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