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1. 发明申请

US20060036284A1 PFO closure devices and related methods of use 有权
公开(公告)号：US20060036284A1
公开(公告)日：2006-02-16
申请号：US11249317
申请日：2005-10-14
申请人： David Blaeser , Peter Keith , Jerome Grudem , Scott Olson , Steven Hackett , Thomas Ressemann , Joel Phillips , Mark Christianson , Dennis Wahr
发明人： David Blaeser , Peter Keith , Jerome Grudem , Scott Olson , Steven Hackett , Thomas Ressemann , Joel Phillips , Mark Christianson , Dennis Wahr
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/00491 , A61B17/0057 , A61B17/0401 , A61B2017/00575 , A61B2017/00592 , A61B2017/00615 , A61B2017/0409 , A61B2017/0458 , A61B2017/0464 , A61B2017/0474 , A61B2017/0496 , A61B2017/22051
摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

2. 发明申请

US20050131447A1 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US20050131447A1
公开(公告)日：2005-06-16
申请号：US11034824
申请日：2005-01-14
申请人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
发明人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
IPC分类号： A61B17/00 , A61B17/12 , A61B17/22 , A61B19/00 , A61F2/06 , A61F2/82 , A61F2/84 , A61M25/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Prior to advancing a device across a stenosis to be treated, normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped. While blood flow is stopped, the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。抽真空组件包括限定具有近端和远端的抽空腔的细长管。近侧密封表面设置在管的近端部分上，并被构造成与引导导管的内腔形成密封。远端密封表面设置在管的远端部分上并构造成与血管形成密封。使用排气鞘组件治疗血管的方法包括通过引导导管将排空鞘组件推进到血管中。在将装置推进通过待治疗的狭窄之前，停止在狭窄附近的血管中的正常顺行血流。当血流停止时，狭窄处理。在血管内引起逆行血流，以便在处理进入抽真空鞘组件期间将栓塞物移走。

3. 发明申请

US20060036282A1 Closure devices, related delivery methods and tools, and related methods of use 有权
公开(公告)号：US20060036282A1
公开(公告)日：2006-02-16
申请号：US11198325
申请日：2005-08-08
申请人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
发明人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2018/00214 , A61B2018/00273 , A61B2018/00351
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor also includes a plurality of arms and preferably does not include a cover. Preferably, the elongate member has a first end of fixedly connected to the left atrial anchor and a portion, proximal to the first end, releasably connected to the right atrial anchor. Preferably, the elongate member is flexible.

4. 发明申请

US20060116659A1 Emboli protection device and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US20060116659A1
公开(公告)日：2006-06-01
申请号：US11337126
申请日：2006-01-19
申请人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
发明人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
IPC分类号： A61M31/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a lesion within a blood vessel, e.g., a coronary artery, includes advancing a sheath into the blood vessel, the sheath having a lumen extending to a port at a distal end of the sheath and further having an occlusive member within a distal region of the sheath. The occlusive member is then positioned within the blood vessel proximal to the lesion. Subsequently, the occlusive member is deployed, thereby stopping antegrade flow across the lesion. A contrast agent can then be infused through a port in the sheath. A dilation balloon is then advanced across the lesion. Suction is then applied to the lumen to induce retrograde flow across the lesion after dilating the lesion.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。治疗血管（例如冠状动脉）内的病变的方法包括使鞘进入血管，护套具有延伸到护套远端端口处的内腔，并且还具有闭塞构件护套的远端区域。然后将闭塞性构件定位在靠近病变的血管内。随后，闭塞成员被部署，从而阻止穿过病变的顺行流动。然后可以通过护套中的端口注入造影剂。然后将扩张气囊推进穿过病变。然后在扩张病变之后，将吸引应用于管腔以诱导穿过病变的逆行流。

5. 发明申请

US20050267526A1 Closure devices, related delivery methods and tools, and related methods of use 审中-公开
标题翻译：关闭装置，相关的运送方式和工具以及相关的使用方法
公开(公告)号：US20050267526A1
公开(公告)日：2005-12-01
申请号：US11185951
申请日：2005-07-21
申请人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
发明人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
IPC分类号： A61B17/00 , A61B17/12 , A61B18/14 , A61M25/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2018/00214 , A61B2018/00273 , A61B2018/00351
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor also includes a plurality of arms and preferably does not include a cover. Preferably, the elongate member has a first end of fixedly connected to the left atrial anchor and a portion, proximal to the first end, releasably connected to the right atrial anchor.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚右心房锚优选地包括多个臂和附接到臂的盖。左心房锚还包括多个臂，优选地不包括盖。优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的可释放地连接到右心房锚的部分。

6. 发明申请

US20070255210A1 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US20070255210A1
公开(公告)日：2007-11-01
申请号：US11824451
申请日：2007-06-29
申请人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
发明人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
IPC分类号： A61M29/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a blood vessel, includes providing an elongate member having proximal and distal ends, a lumen therebetween, the distal end having a braided sheath expandable between a reduced and expanded diameter, and a fluid-tight covering. The elongate member is advanced into a blood vessel that supplies blood to the heart. The braided sheath is expanded to engage the endoluminal surface of the blood vessel and stop antegrade flow.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。一种治疗血管的方法，包括提供具有近端和远端的细长构件，其间的腔，所述远端具有可在缩径和扩张直径之间扩张的编织护套和流体密封的覆盖物。细长构件前进到向心脏供应血液的血管。编织的鞘被扩张以接合血管的内腔表面并停止顺行的流动。

7. 发明授权

US5645533A Apparatus and method for performing an intravascular procedure and exchanging an intravascular device 失效
标题翻译：用于进行血管内手术和交换血管内装置的装置和方法
公开(公告)号：US5645533A
公开(公告)日：1997-07-08
申请号：US379091
申请日：1995-01-26
申请人： David Blaeser , Janita Burmeister , Peter Keith , Thomas Ressemann
发明人： David Blaeser , Janita Burmeister , Peter Keith , Thomas Ressemann
IPC分类号： A61M25/00 , A61M29/02
CPC分类号： A61M25/104 , A61M2025/0004 , A61M2025/0047 , A61M2025/0079 , A61M2025/0098 , A61M2025/0175 , A61M2025/0183 , A61M2025/1063 , A61M2025/1079 , A61M2025/1093 , A61M25/0067 , A61M25/0069 , A61M25/0075
摘要： A method and apparatus are provided for performing a balloon angioplasty procedure and for exchanging a guide wire and an intravascular catheter during the procedure. An intravascular balloon catheter includes an elongated shaft having a proximal portion adapted to extend outside the body of a patient during use, a distal portion adapted for connection to a dilation balloon and adapted for positioning intravascularly during use, and an inflation lumen extending therethrough in fluid flow communication with the balloon. In one aspect of the invention, an elongated guide lumen is connected to the catheter such that the guide lumen and catheter are movable relative to each other during use. A proximal portion of the guide lumen is adapted to extend outside the body of a patient during use, and a distal portion of the guide lumen is adapted to extend distally of the balloon during use. In another aspect of the invention, one or both of a guide wire and an intravascular device can be withdrawn from the guide lumen while the guide lumen remains substantially stationary. In yet another aspect of the invention, proximal and distal seal members are adapted to provide a substantially sealing fit around an intravascular device to inhibit the egress of fluid from the balloon.
摘要翻译：提供了一种用于执行球囊血管成形术程序并在手术期间更换导丝和血管内导管的方法和装置。血管内气囊导管包括细长轴，其具有适于在使用期间延伸到患者身体外部的近端部分，适于连接到扩张气囊的远端部分，并且适于在使用期间血管内定位，以及在流体中延伸穿过的充气腔与气球的流动通信。在本发明的一个方面，细长的引导腔连接到导管，使得引导腔和导管在使用期间可相对于彼此移动。引导腔的近端部分适于在使用期间延伸到患者身体的外部，并且引导腔的远侧部分适于在使用期间向远端延伸。在本发明的另一方面，引导管和血管内装置中的一个或两个可以在引导腔保持基本上静止的同时从引导腔中取出。在本发明的另一方面，近端和远端密封构件适于提供围绕血管内装置的基本密封配合，以抑制流体从气囊的流出。

8. 发明申请

US20060009800A1 Closure devices, related delivery methods, and related methods of use 有权
标题翻译：关闭装置，相关的运送方式和相关的使用方法
公开(公告)号：US20060009800A1
公开(公告)日：2006-01-12
申请号：US10934735
申请日：2004-09-07
申请人： Mark Christianson , Scott Olson , Edward Anderson , Philip Haarstad , Douglas Krone , Dennis Wahr , David Blaeser
发明人： Mark Christianson , Scott Olson , Edward Anderson , Philip Haarstad , Douglas Krone , Dennis Wahr , David Blaeser
IPC分类号： A61B17/08 , A61D1/00
CPC分类号： A61B17/0057 , A61B17/22032 , A61B17/221 , A61B90/39 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/2215 , A61F2002/011
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. A system for delivering the closure device includes side-by-side tubes. A device for retrieving a mis-deployed closure device includes a shaft portion and an expandable retrieval portion.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚用于输送封闭装置的系统包括并排管。用于检索错误展开的闭合装置的装置包括轴部分和可扩张的回缩部分。

9. 发明申请

US20070066994A1 Closure devices, related delivery methods, and related methods of use 审中-公开
标题翻译：关闭装置，相关的运送方式和相关的使用方法
公开(公告)号：US20070066994A1
公开(公告)日：2007-03-22
申请号：US11522193
申请日：2006-09-16
申请人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
发明人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor preferably also includes a plurality of arms and preferably does not include a cover. Preferably, the elongate member has a first end fixedly connected to the left atrial anchor and a portion, proximal to the first end, passing through the right atrial anchor. Preferably, the elongate member is flexible.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚右心房锚优选地包括多个臂和附接到臂的盖。左心房锚固件优选地还包括多个臂，并且优选地不包括盖。优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的部分，穿过右心房锚。优选地，细长构件是柔性的。

10. 发明申请

US20070016250A1 Closure devices, related delivery methods, and related methods of use 有权
标题翻译：关闭装置，相关的运送方式和相关的使用方法
公开(公告)号：US20070016250A1
公开(公告)日：2007-01-18
申请号：US11522158
申请日：2006-09-16
申请人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
发明人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor preferably also includes a plurality of arms and preferably, does not include a cover. Preferably, the elongate member has a first end fixedly connected to the left atrial anchor and a portion, proximal to the first end, passing through the right atrial anchor. Preferably, the elongate member is flexible.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚右心房锚优选地包括多个臂和附接到臂的盖。左心房锚优选地还包括多个臂，优选地不包括盖。优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的部分，穿过右心房锚。优选地，细长构件是柔性的。

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