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1. 发明授权

US07323200B2 Calcium fortified, soy based, infant nutritional formulas 失效
标题翻译：钙强化，大豆，婴幼儿营养配方
公开(公告)号：US07323200B2
公开(公告)日：2008-01-29
申请号：US10642870
申请日：2003-08-18
申请人： James N. Chmura , Kent L. Cipollo , Louis I. Ndife , Karin M. Ostrom
发明人： James N. Chmura , Kent L. Cipollo , Louis I. Ndife , Karin M. Ostrom
IPC分类号： A23L1/20
CPC分类号： A23L2/52 , A23L33/16 , A23L33/185 , A23L33/40 , A23V2002/00 , Y10S426/801 , A23V2250/5488 , A23V2250/1578
摘要： Disclosed are calcium fortified, soy-based, infant nutritional formulas, including powder, liquid, or concentrate embodiments comprising per 100 kcal of formula (A) lipid, preferably up to about 8.0 g, (B) carbohydrate, preferably from about 8.0 g to about 16.0 g, (C) phytase-treated soy protein, preferably up to about 3.5 g and (D) calcium, preferably up to about 90 mg of calcium; wherein the nutritional formula is an infant formula having a calcium to lipid weight ratio of from about 0.002 to about 0.020, and wherein the formula contains not more than about 8.4 mg phytic acid per 100 kcal of formula. It has been found that these calcium-fortified, phytase-treated, soy-based, nutritional formulas provide for softer stools in infant populations, especially as compared to infants fed with other soy-based formulas including commercial soy formulas as well as soy based formulas derived from dephytinization methods other than phytase treatment, e.g., ion exchange.
摘要翻译：公开了钙强化的大豆基的婴儿营养配方，包括粉末，液体或浓缩物实施方案，其包含每100kcal式（A）脂质，优选至多约8.0g（B）碳水化合物，优选约8.0g至约16.0g，（C）植酸酶处理的大豆蛋白，优选至多约3.5g和（D）钙，优选至多约90mg的钙; 其中所述营养配方是具有约0.002至约0.020的钙与脂质重量比的婴儿配方，并且其中所述配方包含不超过约8.4mg植酸/ 100kcal配方。已经发现，这些钙强化植酸酶处理的大豆基营养配方提供了婴幼儿的较软的粪便，特别是与喂养其他大豆基配方的婴儿相比，其中包括商业大豆配方以及大豆基配方衍生自植酸酶处理以外的脱氢方法，例如离子交换。

2. 发明授权

US06440469B1 Plant protein for nutritional products and method of making same 有权
标题翻译：营养产品的植物蛋白及其制作方法
公开(公告)号：US06440469B1
公开(公告)日：2002-08-27
申请号：US09397725
申请日：1999-09-17
申请人： John D. Suh , Karin M. Ostrom , Louis I. Ndife , Paul S. Anloague , James N. Chmura , Andre Daab-Krzykowski , Paul W. Johns , Diane M. Garcia , Terrence B. Mazer , Fu-i Mei
发明人： John D. Suh , Karin M. Ostrom , Louis I. Ndife , Paul S. Anloague , James N. Chmura , Andre Daab-Krzykowski , Paul W. Johns , Diane M. Garcia , Terrence B. Mazer , Fu-i Mei
IPC分类号： A61K3578
CPC分类号： A23J3/14 , A23J3/16 , A23L5/273 , A23L11/34 , A23L33/11 , Y10S426/801
摘要： The present invention relates generally to a method of producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese or nucleotides. More specifically, this invention is directed to a method of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. This invention is also directed to the plant protein product resulting from the inventive process and to nutritional products that use the plant protein product as a source of amino nitrogen.
摘要翻译：本发明一般涉及一种生产植物蛋白的方法，所述植物蛋白用于降低植物雌激素，锰或核苷酸水平的营养产品中。更具体地，本发明涉及使用离子交换技术从植物蛋白中去除植物雌激素，锰或核苷酸的方法。本发明还涉及由本发明方法产生的植物蛋白质产物和使用植物蛋白产物作为氨基氮源的营养产品。

3. 发明授权

US5804234A Plant protein for nutritional products and method of making same 失效
公开(公告)号：US5804234A
公开(公告)日：1998-09-08
申请号：US713904
申请日：1996-09-13
申请人： John D. Suh , Karin M. Ostrom , Louis I. Ndife , Paul S. Anloague , James N. Chmura , Andre Daab-Krzykowski , Paul W. Johns , Diane M. Garcia , Terrence B. Mazer , Fu-I Mei
发明人： John D. Suh , Karin M. Ostrom , Louis I. Ndife , Paul S. Anloague , James N. Chmura , Andre Daab-Krzykowski , Paul W. Johns , Diane M. Garcia , Terrence B. Mazer , Fu-I Mei
IPC分类号： A23J3/14 , A23J3/16 , A23L1/015 , A23L1/211 , A23L1/30 , A23K1/02 , A01N43/04 , A01N65/00
CPC分类号： A23J3/14 , A23J3/16 , A23L11/34 , A23L33/11 , A23L5/273 , Y10S426/801
摘要： The present invention relates generally to a method of producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese or nucleotides. More specifically, this invention is directed to a method of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. This invention is also directed to the plant protein product resulting from the inventive process and to nutritional products that use the plant protein product as a source of amino nitrogen.

4. 发明授权

US5985338A Plant protein for nutritional products and method of making same 失效
公开(公告)号：US5985338A
公开(公告)日：1999-11-16
申请号：US163493
申请日：1998-06-30
申请人： John D. Suh , Karin M. Ostrom , Louis I. Ndife , Paul S. Anloague , James N. Chmura , Andre Daab-Krzykowski , Paul W. Johns , Diane M. Garcia , Terrence B. Mazer , Fu-I Mei
发明人： John D. Suh , Karin M. Ostrom , Louis I. Ndife , Paul S. Anloague , James N. Chmura , Andre Daab-Krzykowski , Paul W. Johns , Diane M. Garcia , Terrence B. Mazer , Fu-I Mei
IPC分类号： A23J3/14 , A23J3/16 , A23L1/015 , A23L1/211 , A23L1/30 , A23K1/02 , A23L1/00
CPC分类号： A23J3/14 , A23J3/16 , A23L11/34 , A23L33/11 , A23L5/273 , Y10S426/801
摘要： The present invention relates generally to a method of producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese or nucleotides. More specifically, this invention is directed to a method of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. This invention is also directed to the plant protein product resulting from the inventive process and to nutritional products that use the plant protein product as a source of amino nitrogen.

5. 发明授权

US06313273B1 Soy proteins and methods for their production 有权
标题翻译：大豆蛋白及其生产方法
公开(公告)号：US06313273B1
公开(公告)日：2001-11-06
申请号：US09382966
申请日：1999-08-25
申请人： Ronald L. Thomas , Louis I. Ndife , Hilary Shallo , Lynn P. Nelles
发明人： Ronald L. Thomas , Louis I. Ndife , Hilary Shallo , Lynn P. Nelles
IPC分类号： A23J114
CPC分类号： A23J1/14 , A23V2002/00 , A23V2300/34 , A23V2250/5488
摘要： A high quality soy protein concentrate (SPC) was produced by a process of enzyme treatment combined with ultrafiltration. Soy flour, the starting material, was enzymatically treated with commercial pectinases and diafiltered with a porous stainless steel ultrafiltration system. The resulting product had reduced levels of physic acid and nucleic acids due to contaminant phytase and nuclease activity in the pectinase enzymes. The functionality of the SPC was improved due to increased solubility compared to conventional soy isolates produced by acid precipitation. High performance liquid chromatography gel filtration profiles indicated that the proteins in the SPC remained intact. The SPC also had reduced flavor when compared to the original soy flour according to gas chromatography flavor profiles and sensory evaluation.
摘要翻译：通过与超滤结合的酶处理方法生产高品质大豆蛋白浓缩物（SPC）。大豆粉，起始原料，用商业果胶酶进行酶处理，并用多孔不锈钢超滤系统进行渗滤。所得产物由于果胶酶中的污染物植酸酶和核酸酶活性而降低了物理酸和核酸的水平。与通过酸沉淀生产的常规大豆分离物相比，由于增加的溶解度，SPC的功能得到改善。高效液相色谱凝胶过滤曲线表明，SPC中的蛋白质保持不变。与原始大豆粉相比，根据气相色谱风味和感官评价，SPC也具有降低的风味。

6. 发明授权

US5248502A Method for decreasing the allergenicity of psyllium seed husk by alkaline treatment 失效
标题翻译：通过碱处理降低磷酸钙的过敏症的方法
公开(公告)号：US5248502A
公开(公告)日：1993-09-28
申请号：US789309
申请日：1991-11-08
申请人： Louis I. Ndife
发明人： Louis I. Ndife
IPC分类号： A61K36/68
CPC分类号： A61K36/68 , Y10S514/885 , Y10S514/892
摘要： A method of reducing the allergenicity of psyllium seed husk. Psyllium seed husk is treated with a alkaline solution at a temperature and for a time sufficient to reduce the allergenicity of the psyllium seed husk.
摘要翻译：降低欧车前草种皮过敏原的方法。车前子壳种子在碱性溶液中在足以降低欧车前壳的过敏原性的温度和时间下进行处理。

7. 发明申请

US20090005544A1 Process for Making Soy Protein Isolates 审中-公开
标题翻译：制作大豆蛋白分离物的方法
公开(公告)号：US20090005544A1
公开(公告)日：2009-01-01
申请号：US12145776
申请日：2008-06-25
申请人： Louis I. Ndife , Chad R. Cole , Jeffrey H. Baxter
发明人： Louis I. Ndife , Chad R. Cole , Jeffrey H. Baxter
IPC分类号： C07K1/30
CPC分类号： A23J3/16 , A23J1/14 , A23L11/07 , A23L11/32 , A23L33/165 , A23L33/185 , A23V2002/00 , A23V2250/5488 , A23V2250/1578 , A23V2250/1612
摘要： Disclosed is a process comprising: mixing a soy protein-containing material with an aqueous medium; removing the non-solubilized solids from the slurry to form an alkaline liquid containing solubilized soy protein; adjusting the pH of the solubilized soy protein liquid to between about 3.8 and about 6.6, to precipitate soy protein from the liquid; separating the precipitated soy protein from the pH-adjusted soy protein liquid; resolubilizing the separated soy protein precipitate in an aqueous medium at a pH of from about 1.8 to 3.2; treating the resolubilized soy protein with at least one water-soluble calcium salt to form a calcium-enriched soy protein mixture; precipitating soy protein from the calcium-enriched soy protein mixture by adjusting the pH of the mixture to between about 3.8 and about 6.6; separating the precipitated soy protein from the calcium-enriched soy protein mixture; and washing to form calcium-enriched soy protein isolate having selectively reduced manganese concentrations.
摘要翻译：公开了一种方法，其包括：将含大豆蛋白的材料与水性介质混合; 从浆液中除去未溶解的固体以形成含有溶解大豆蛋白的碱性液体; 将溶解的大豆蛋白液体的pH调节至约3.8至约6.6，以从液体中沉淀大豆蛋白; 将沉淀的大豆蛋白与pH调节的大豆蛋白液体分离; 将分离的大豆蛋白沉淀物在约1.8至3.2的pH下在水性介质中重新溶解; 用至少一种水溶性钙盐处理所述再溶解的大豆蛋白以形成富含钙的大豆蛋白混合物; 通过将混合物的pH调节至约3.8至约6.6，从富钙大豆蛋白混合物中沉淀大豆蛋白; 将沉淀的大豆蛋白与富钙大豆蛋白混合物分离; 并洗涤以形成具有选择性还原的锰浓度的富钙大豆蛋白分离物。

8. 发明授权

US5489440A Rice flour-based oral rehydration solution 失效
标题翻译：米粉口服补液方案
公开(公告)号：US5489440A
公开(公告)日：1996-02-06
申请号：US398707
申请日：1995-03-06
申请人： Louis I. Ndife , Paul S. Anloague , Rosa C. B. Beach , Michelle M. B. Rushlow , Michael J. Neylan
发明人： Louis I. Ndife , Paul S. Anloague , Rosa C. B. Beach , Michelle M. B. Rushlow , Michael J. Neylan
IPC分类号： A23J3/34 , A23L1/105 , A23L1/305 , A61K9/14
CPC分类号： C12Y302/01001 , A23J3/346 , A23L33/185 , A23L7/107 , C12Y302/01004 , C12Y304/00 , A23V2002/00
摘要： A method for producing an improved rice flour-based oral rehydration solution using the enzymes cellulase and protease is disclosed. The oral rehydration solution of the invention has low viscosity, low osmolality, and can be ingested through the nipple of a bottle. The oral rehydration product can also be dried into powder form before packaging and reconstituted at the time of use. The product is designed to treat individuals with severe diarrhea brought about by cholera or other causes.
摘要翻译：公开了一种使用酶纤维素酶和蛋白酶制备改进的基于米粉的口服补液溶液的方法。本发明的口服补液溶液具有低粘度，低渗透压，并且可以通过瓶的乳头摄取。口服补液产品也可以在使用前在包装和重新配制之前干燥成粉末形式。该产品旨在治疗由霍乱或其他原因引起的严重腹泻患者。

9. 发明授权

US07070825B2 Infant formula 有权
标题翻译：婴幼儿配方奶粉
公开(公告)号：US07070825B2
公开(公告)日：2006-07-04
申请号：US10603464
申请日：2003-06-25
申请人： Louis I. Ndife , Booker T. Lucas, III , Stephene L. Hohman
发明人： Louis I. Ndife , Booker T. Lucas, III , Stephene L. Hohman
IPC分类号： A23C9/18
CPC分类号： A61K9/0095 , A23C9/18 , A23L33/40 , A23P10/28 , A61K9/0056 , A61K9/2095 , Y10S426/801
摘要： The present invention is directed to a new unit dose packaging for infant formula. The infant formula is manufactured as a tablet. One tablet will typically contain sufficient nutrients to produce a single serving of the formula (i.e. the amount of formula an average infant consumes in a single feeding). Other aspects of the invention are directed to feeding an infant such a reconstituted tablet and packaging containing such infant formula tablets.
摘要翻译：本发明涉及用于婴儿配方奶粉的新的单位剂量包装。婴儿配方奶粉以片剂的形式制造。一个片剂通常将含有足够的营养物质以产生单一配方（即单次喂食中平均婴儿消耗的配方奶粉量）。本发明的其它方面涉及喂养婴儿如重构片剂和含有这种婴儿配方药片的包装。

10. 发明授权

US06475539B1 Nutritionally complete low pH enteral formula 有权
标题翻译：营养完整的低pH肠溶配方
公开(公告)号：US06475539B1
公开(公告)日：2002-11-05
申请号：US09293411
申请日：1999-04-16
申请人： Normanella T. DeWille , Jeffrey G. Morris , Terrence B. Mazer , Paul S. Anloague , Amanda L. Smeller , Michael A. Chandler , Diane M. Garcia , Louis I. Ndife
发明人： Normanella T. DeWille , Jeffrey G. Morris , Terrence B. Mazer , Paul S. Anloague , Amanda L. Smeller , Michael A. Chandler , Diane M. Garcia , Louis I. Ndife
IPC分类号： A23B412
CPC分类号： A23L2/66 , A23L2/38 , A23L33/115 , A23L33/15 , A23L33/16 , A23L33/19 , A23L33/40 , A23V2002/00 , A23V2250/628 , A23V2250/5114 , A23V2250/5424 , A23V2250/188 , A23V2250/032 , A23V2250/5072 , A23V2250/0616 , A23V2250/1944 , A23V2250/02 , A23V2250/156 , A23V2250/51084 , A23V2250/54246 , A23V2250/5108 , A23V2250/708 , A23V2250/704 , A23V2250/702 , A23V2250/712 , A23V2250/71 , A23V2250/5118 , A23V2250/54252
摘要： This invention is directed to a low pH nutritional formula that contains high levels of macronutrients, vitamins and minerals. The pH of the enteral formula is from about 3.0-4.6 and delivers at least 25% of the RDI for selected vitamins and minerals in a 237 ml. serving. The enteral formula uses a stabilizing system comprising high methoxy pectin to stabilize the protein and a unique process to produce the formula.
摘要翻译：本发明涉及含有高水平的营养素，维生素和矿物质的低pH营养配方。肠内配方的pH值约为3.0-4.6，并在237毫升中为选定的维生素和矿物质提供至少25％的RDI。服务。肠内配方使用包含高甲氧基果胶的稳定体系来稳定蛋白质和产生该配方的独特方法。

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