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1. 发明授权

US09103809B2 Liquid handler with dual pipetting groups 有权
标题翻译：具有双吸移组的液体处理器
公开(公告)号：US09103809B2
公开(公告)日：2015-08-11
申请号：US13453867
申请日：2012-04-23
申请人： Daniel West , David Knorr , James E. Young , Kimberly Subrahmanyan , Nicholas Fleming , Randy K. Roushall
发明人： Daniel West , David Knorr , James E. Young , Kimberly Subrahmanyan , Nicholas Fleming , Randy K. Roushall
IPC分类号： B01L3/02 , G01N35/10 , G01F11/00
CPC分类号： G01N35/1065 , B01L3/02 , B01L2200/0605 , B01L2200/0642 , G01F11/006 , G01N2035/1076 , Y10T29/49826
摘要： An automated liquid handling system is disclosed. A system includes a first pipetting group, which includes at least one pipettor, movably arranged on a first arm; and a second pipetting group, which includes at least one pipettor, movably arranged on a second arm, wherein the first arm and the second arm are movably arranged on at least one track such that the first arm and the second arm can independently move along the at least one track while keeping the first arm parallel with the second arm, wherein the at least one pipettor of the first pipetting group is arranged on a side of the first arm facing the second pipetting group, wherein the at least one pipettor of the second pipetting group is arranged on a side of the second arm facing the first pipetting group.
摘要翻译：公开了一种自动化液体处理系统。一种系统包括第一吸移组，其包括至少一个移液器，可移动地布置在第一臂上; 以及第二吸移组，其包括可移动地布置在第二臂上的至少一个移液器，其中所述第一臂和所述第二臂可移动地布置在至少一个轨道上，使得所述第一臂和所述第二臂可以独立地沿着所述第二臂移动，至少一个轨道，同时保持所述第一臂与所述第二臂平行，其中所述第一吸移组的所述至少一个吸移管布置在所述第一臂的面向所述第二吸移组的一侧上，其中所述第二移液管的所述至少一个移液管移液组布置在第二臂的面向第一移液组的一侧。

2. 发明授权

US5262031A Electroosmotic flow control apparatus for capillary electrophoresis 失效
标题翻译：用于毛细管电泳的电渗流量控制装置
公开(公告)号：US5262031A
公开(公告)日：1993-11-16
申请号：US834174
申请日：1992-02-07
申请人： Jurgen A. Lux , Sally A. Swedberg , James E. Young , Douglass McManigill
发明人： Jurgen A. Lux , Sally A. Swedberg , James E. Young , Douglass McManigill
IPC分类号： G01N27/447 , G01N27/26
CPC分类号： G01N27/44713 , G01N27/44752
摘要： An electrophoretic apparatus that is useful for separation of analytes, such as proteins, comprises a capillary tube that has an interfacial layer bonded to reduce interactions between the bore and analytes during electroosmotic flow through the capillary, and an electrically modified media carried by or contacting a capillary wall outward from the bore. The modified media can be an electrically resistive coating or an electrically conductive coating. Together with appropriate power supply configurations, the electrically modified media permits the application of a voltage gradient that is transverse to the electrophoretic gradient, and provides electroosmotic flow control in cooperation with the interfacial layer.
摘要翻译：可用于分离分析物如蛋白质的电泳装置包括毛细管，其具有结合的界面层，以减少通过毛细管的电渗流过程中的孔和分析物之间的相互作用，以及由毛细管壁从孔内向外。改性介质可以是电阻涂层或导电涂层。与适当的电源配置一起，电修改的介质允许施加横向于电泳梯度的电压梯度，并且与界面层协作提供电渗流控制。

3. 发明授权

US4407280A Disposable hood 失效
标题翻译：一次性罩
公开(公告)号：US4407280A
公开(公告)日：1983-10-04
申请号：US274182
申请日：1981-06-16
申请人： W. Edgar Trammell , James E. Young , James R. Chidester , Ralph S. Walker
发明人： W. Edgar Trammell , James E. Young , James R. Chidester , Ralph S. Walker
IPC分类号： A61M16/06 , A61M16/02
CPC分类号： A61M16/06 , A61M16/0627 , Y10S128/91
摘要： A disposable hood of unitary one-piece construction for maintaining a desired gas atmosphere about the head of a patient incorporates a novel attachment means for connecting a flexible conduit or hose to the hood. The hood itself is a generally bubble-shaped chamber molded of a transparent material with the top and sidewalls being joined in arcuate contours so that there are no sharp corners. Flat extension means extend from the bottom of the hood so as to lie flatwise on the bed, and an arcuate ballast member is adapted to fit closely around the hood and on the flat extension means to hold the hood in position on the bed.
摘要翻译：用于在患者头部保持期望的气体气氛的整体式单件结构的一次性罩具有用于将柔性导管或软管连接到罩的新型附接装置。罩本身是由透明材料模制的通常为气泡形的室，顶部和侧壁以弓形轮廓连接，使得没有尖角。扁平延伸装置从罩的底部延伸以平躺在床上，并且弧形压载件适于紧密地配合在发动机罩和平坦的延伸装置上以将发动机罩保持在床上的适当位置。

4. 发明申请

US20130280145A1 LIQUID HANDLER WITH DUAL PIPETTING GROUPS 有权
标题翻译：液体处理器与双管道组
公开(公告)号：US20130280145A1
公开(公告)日：2013-10-24
申请号：US13453867
申请日：2012-04-23
申请人： Daniel West , David Knorr , James E. Young , Kimberly Subrahmanyan , Nicholas Fleming , Randy K. Roushall
发明人： Daniel West , David Knorr , James E. Young , Kimberly Subrahmanyan , Nicholas Fleming , Randy K. Roushall
IPC分类号： B01L3/02 , B23P11/00
CPC分类号： G01N35/1065 , B01L3/02 , B01L2200/0605 , B01L2200/0642 , G01F11/006 , G01N2035/1076 , Y10T29/49826
摘要： An automated liquid handling system is disclosed. A system includes a first pipetting group, which includes at least one pipettor, movably arranged on a first arm; and a second pipetting group, which includes at least one pipettor, movably arranged on a second arm, wherein the first arm and the second arm are movably arranged on at least one track such that the first arm and the second arm can independently move along the at least one track while keeping the first arm parallel with the second arm, wherein the at least one pipettor of the first pipetting group is arranged on a side of the first arm facing the second pipetting group, wherein the at least one pipettor of the second pipetting group is arranged on a side of the second arm facing the first pipetting group.
摘要翻译：公开了一种自动化液体处理系统。一种系统包括第一吸移组，其包括至少一个移液器，可移动地布置在第一臂上; 以及第二吸移组，其包括可移动地布置在第二臂上的至少一个移液器，其中所述第一臂和所述第二臂可移动地布置在至少一个轨道上，使得所述第一臂和所述第二臂可以独立地沿着所述第二臂移动，至少一个轨道，同时保持所述第一臂与所述第二臂平行，其中所述第一吸移组的所述至少一个吸移管布置在所述第一臂的面向所述第二吸移组的一侧上，其中所述第二移液管的所述至少一个移液管移液组布置在第二臂的面向第一移液组的一侧。

5. 发明申请

US20080032290A1 Nanopore flow cells 审中-公开
标题翻译：纳米孔流动池
公开(公告)号：US20080032290A1
公开(公告)日：2008-02-07
申请号：US11498566
申请日：2006-08-03
申请人： James E. Young
发明人： James E. Young
IPC分类号： C12Q1/68 , C12M3/00
CPC分类号： G01N15/1031 , B01L3/5027 , C12Q1/6869 , G01N33/48721
摘要： Systems and methods for nanopore flow cells are provided.
摘要翻译：提供了纳米孔流动池的系统和方法。

6. 发明授权

US5700106A Island form 失效
标题翻译：岛形式
公开(公告)号：US5700106A
公开(公告)日：1997-12-23
申请号：US614283
申请日：1996-03-12
申请人： James E. Young , Roy A. Meyer
发明人： James E. Young , Roy A. Meyer
IPC分类号： E01F1/00 , E01C11/22
CPC分类号： E01F1/00
摘要： An easily assembled concrete form including a plurality of elongated wall members manufactured by roll forming and connected together to define an enclosure. Each wall member has a first end and a second end, an inner surface and an outer surface. Attached to the inner surface of the wall member at the first end is a U-shaped key having legs extending beyond the first end of the wall member. Attached to the inner surface of the wall member at the second end is an interlocking bracket having two vertically spaced slots for receiving the legs of the U-shaped key to connect adjacent wall members together. One of the slots is enlarged for also receiving an extending flange from a support bracket to frictionally maintain the U-shaped key and interlocking bracket in a locked relationship.
摘要翻译：一种易于组装的混凝土形式，其包括通过辊轧成型制造并连接在一起以限定外壳的多个细长壁构件。每个壁构件具有第一端和第二端，内表面和外表面。在第一端处附接到壁构件的内表面的是具有延伸超过壁构件的第一端的腿的U形钥匙。在第二端处附接到壁构件的内表面的是互锁支架，其具有两个垂直间隔的槽，用于接收U形钥匙的腿以将相邻的壁构件连接在一起。其中一个槽被放大，用于从支撑托架接收延伸的凸缘以摩擦地保持U形键和互锁支架处于锁定关系。

7. 发明授权

US5312295A Subterranean transformer enclosure vent 失效
标题翻译：地下变压器外壳通风口
公开(公告)号：US5312295A
公开(公告)日：1994-05-17
申请号：US110732
申请日：1993-08-23
申请人： James E. Young
发明人： James E. Young
IPC分类号： F24F13/08 , F24F7/00
CPC分类号： F24F13/08
摘要： A heat venting system for subterranean transformer enclosures for sidewalks or streets includes a vent guard that passes air but prevents solids and fluids such as destructive oil from dropping upon the transformers. Used in connection with a vent plate having very many small holes will prevent leaves and sticks from clogging the vent and destroying the transformers.
摘要翻译：用于人行道或街道的用于地下变压器外壳的散热系统包括通风孔，其通过空气但防止固体和诸如破坏性油的流体掉入变压器。与具有非常多的小孔的排气孔相连用，可防止叶片和棒块堵塞排气孔并破坏变压器。

8. 发明授权

US5180475A System and method for controlling electroosmotic flow 失效
标题翻译：用于控制电渗流的系统和方法
公开(公告)号：US5180475A
公开(公告)日：1993-01-19
申请号：US754797
申请日：1991-09-04
申请人： James E. Young , Douglass McManigill , Jurgen A. Lux
发明人： James E. Young , Douglass McManigill , Jurgen A. Lux
IPC分类号： B01D57/02 , G01N27/447
CPC分类号： G01N27/44752 , G01N27/44713
摘要： A system and method for controlling the rate of electroosmotic flow in capillary electrophoresis. A first high voltage power supply is electrically connected to the inlet end of a capillary tube, while a second high voltage power supply is connected at an outlet end. The potential difference across the capillary tube is therefore the difference between the high voltages. Electroosmotic flow can be controlled by varying the two high voltages correspondingly to maintain the same potential difference but to achieve a different voltage offset relative to ground. Optionally, the voltage offset may be varied during electrophoresis analysis to slow migration during periods in which constituents are closely spaced and to speed migration when constituents are sufficiently spaced apart. A conductive capillary tube coating which is preferably grounded defines an external control area for electroosmotic flow. A detector is located downstream of the external control area, so that the coating is a unitary layer.

9. 发明授权

US5131997A Capillary zone electrophoresis cassette 失效
标题翻译：毛细管电泳仪
公开(公告)号：US5131997A
公开(公告)日：1992-07-21
申请号：US522278
申请日：1990-05-11
申请人： John A. Christianson , Douglass McManigill , James E. Young
发明人： John A. Christianson , Douglass McManigill , James E. Young
IPC分类号： B01D57/02 , G01N27/447
CPC分类号： G01N27/44704
摘要： An apparatus for electrophoretic separation comprising a fixed support structure and a cassette shell which is removably attached to the support device. Within the cassette shell is a basket having symmetrically arranged ribs to secure a capillary tube in a helical configuration. The ribs have notches to receive a loop of the helically wound capillary tube. The notches of the ribs alternate in orientation with respect to the axis of the helically wound capillary tube. A quarter-turn locking member provides electrical, optical and coolant fluid communication between the cassette shell and the support device.

10. 发明授权

US4743831A Apparatus and method for indicating remaining battery life in a battery powered device 失效
标题翻译：用于指示电池供电装置中的剩余电池寿命的装置和方法
公开(公告)号：US4743831A
公开(公告)日：1988-05-10
申请号：US906543
申请日：1986-09-12
申请人： James E. Young
发明人： James E. Young
IPC分类号： G01R31/36 , H02J7/00 , G08B21/00
CPC分类号： G01R31/3648 , G01R31/3675 , H02J7/008 , G01R19/16542 , Y10S320/21
摘要： The remaining battery life of a battery powered device is predicted by monitoring the immediate past history of battery life and employing this immediate past history as a basis for subsequent predictions of the useful life of the battery. By this approach, the present invention is able to take into account the deterioration of battery life which occurs during the life-time of a rechargeable battery. The device includes a data storage means for storing a predetermined value representing the total number of usable hours to be expected to obtain from a fully charged battery during normal use, means for counting the number of hours of actual use of the battery, and means operable in response to the occurrence of a full discharge of the battery in normal use for updating the data storage means to store therein as the predetermined value for the expected useful life of the battery in the next cycle of normal use, the value for the number of hours of use actually obtained from the battery in the current cycle, so that subsequent predictions of the battery life will be based upon the immediate past history of actual battery life.
摘要翻译：电池供电设备的剩余电池寿命通过监控电池寿命的直接过去历史并采用这种直接的过去历史作为随后预测电池的使用寿命的基础来预测。通过这种方法，本发明能够考虑到在可再充电电池的使用寿命期间发生的电池寿命的恶化。该装置包括数据存储装置，用于存储表示在正常使用期间从完全充电的电池获得的可用小时数的总数的预定值，用于对实际使用电池的小时数进行计数的装置，以及可操作的装置响应于正常使用中的电池的完全放电的发生，用于更新数据存储装置以将其存储为在正常使用的下一个周期中电池的预期使用寿命的预定值，在当前周期中实际从电池获得的使用小时数，以便随后对电池寿命的预测将基于实际电池寿命的直接过去历史。

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