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1. 发明授权

US08449772B2 Micro fluidic system and a method of attaching a membrane to a tube 有权
标题翻译：微流体系统和将膜附接到管的方法
公开(公告)号：US08449772B2
公开(公告)日：2013-05-28
申请号：US12064483
申请日：2006-08-22
申请人： Holger Dirac , Per Brandt Rasmussen , Arne Briest
发明人： Holger Dirac , Per Brandt Rasmussen , Arne Briest
IPC分类号： B01D63/00
CPC分类号： A61M1/1678 , A61B5/14532 , A61B10/0045 , Y10T29/49401
摘要： A micro fluidic system comprising at least one tube (1), a membrane (3) and at least one fitting member (4). The fitting member (4) is positioned around the membrane (3) and an end part (2) of the tube(s) (1), thereby fitting the membrane (3) to the end part(s) (2). The fitting member(s) (4) is/are made from a shrinkable material, and it/they is/are fitted tightly around the membrane (3) end part(s) (2). This is obtained by causing the shrinkable material to shrink, e.g. by heating the material, while the fitting member (4) is positioned around the membrane (3) and the end part(s) (2). It is an advantage that the fitting member (4) is made from a shrinkable material because this provides the possibility of fitting the membrane (3) tightly to the end part(s) (2) in an easy and cost effective manner. The micro fluidic system is very suitable for use in a probe, such as a dialysis probe. Also claimed is a method of manufacturing the micro fluidic system.
摘要翻译：一种微流体系统，包括至少一个管（1），膜（3）和至少一个配件（4）。装配构件（4）围绕膜（3）和管（1）的端部（2）定位，从而将膜（3）装配到端部（2）。装配构件（4）由可收缩材料制成，并且/它们紧密地配合在膜（3）端部（2）周围。这是通过使收缩材料收缩而获得的。通过加热材料，同时装配构件（4）围绕膜（3）和端部（2）定位。这是一种优点，即装配构件（4）由可收缩材料制成，因为这提供了以容易和成本有效的方式将膜（3）紧密地装配到端部（2）的可能性。微流体系统非常适合用于探针，例如透析探针。还要求保护的是制造微流体系统的方法。

2. 发明申请

US20090218272A1 MICRO FLUIDIC SYSTEM AND A METHOD OF ATTACHING A MEMBRANE TO A TUBE 有权
标题翻译：微流体系统和将膜连接到管的方法
公开(公告)号：US20090218272A1
公开(公告)日：2009-09-03
申请号：US12064483
申请日：2006-08-22
申请人： Holger Dirac , Per Brandt Rasmussen , Arne Briest
发明人： Holger Dirac , Per Brandt Rasmussen , Arne Briest
IPC分类号： B01D63/00 , B23P17/00
CPC分类号： A61M1/1678 , A61B5/14532 , A61B10/0045 , Y10T29/49401
摘要： A micro fluidic system comprising at least one tube (1), a membrane (3) and at least one fitting member (4). The fitting member (4) is positioned around the membrane (3) and an end part (2) of the tube(s) (1), thereby fitting the membrane (3) to the end part(s) (2). The fitting member(s) (4) is/are made from a shrinkable material, and it/they is/are fitted tightly around the membrane (3) end part(s) (2). This is obtained by causing the shrinkable material to shrink, e.g. by heating the material, while the fitting member (4) is positioned around the membrane (3) and the end part(s) (2). It is an advantage that the fitting member (4) is made from a shrinkable material because this provides the possibility of fitting the membrane (3) tightly to the end parts) (2) in an easy and cost effective manner. The micro fluidic system is very suitable for use in a probe, such as a dialysis probe. Also claimed is a method of manufacturing the micro fluidic system.
摘要翻译：一种微流体系统，包括至少一个管（1），膜（3）和至少一个配件（4）。装配构件（4）围绕膜（3）和管（1）的端部（2）定位，从而将膜（3）装配到端部（2）。装配构件（4）由可收缩材料制成，并且/它们紧密地配合在膜（3）端部（2）周围。这是通过使收缩材料收缩而获得的。通过加热材料，同时装配构件（4）围绕膜（3）和端部（2）定位。这是因为这样可以以容易且成本有效的方式将膜（3）紧密地装配到端部部件（2））的可能性，因此装配构件（4）由可收缩材料制成是有利的。微流体系统非常适合用于探针，例如透析探针。还要求保护的是制造微流体系统的方法。

3. 发明申请

US20090054867A1 Device for Administering of Medication in Fluid Form 有权
标题翻译：用于管理流体形式药物的装置
公开(公告)号：US20090054867A1
公开(公告)日：2009-02-26
申请号：US12195791
申请日：2008-08-21
申请人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
发明人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
IPC分类号： A61M5/14
CPC分类号： A61M5/16881 , A61M5/141 , A61M5/14244 , A61M5/14276 , A61M5/148 , A61M5/152 , A61M5/16804 , A61M5/16813 , A61M5/16854 , A61M2005/1405 , A61M2205/0244 , A61M2205/0294 , A61M2205/3306 , A61M2205/3331
摘要： An infusion device for continuously infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications further contains a holding device for bolus rate of infusion for a short period. The device comprises a flow regulating device comprising a passage defined by at least a fact element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber increases the volume of the second chamber decreases.
摘要翻译：公开了一种用于持续输注药物的输注装置，其中输注通过两个单独的流体通信进行控制。在每个通过限制装置和阀装置控制的流体连通中的输注，并且流体通信中的一个进一步包含用于短时间的推注速率的保持装置。该装置包括流动调节装置，其包括由至少一个事实元件限定的通道，其是适于弹性变形以改变通道的横截面面积的主要可变形元件。此外，该装置包括用于存储和供应流体形式的药物的容器，所述容器包括相对于彼此布置的第一和第二腔室，使得当第一腔室的体积增加时，第二腔室的体积减小。

4. 发明授权

US08945064B2 Device for administering of medication in fluid form 有权
标题翻译：用于以流体形式施用药物的装置
公开(公告)号：US08945064B2
公开(公告)日：2015-02-03
申请号：US12195791
申请日：2008-08-21
申请人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
发明人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
IPC分类号： A61M5/178 , A61M5/168 , A61M5/14 , A61M5/142 , A61M5/148 , A61M5/152
CPC分类号： A61M5/16881 , A61M5/141 , A61M5/14244 , A61M5/14276 , A61M5/148 , A61M5/152 , A61M5/16804 , A61M5/16813 , A61M5/16854 , A61M2005/1405 , A61M2205/0244 , A61M2205/0294 , A61M2205/3306 , A61M2205/3331
摘要： An infusion device for continuous infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications further contains a holding device for bolus rate of infusion. The device comprises a flow regulating device comprising a passage defined by at least a first element and a second element, wherein at least one of the first and second element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber increases the volume of the second chamber decreases.
摘要翻译：公开了用于连续输注药物的输注装置，其中输注通过两个单独的流体通信来控制。在每个流体通路中通过限制装置和阀装置控制输注，并且流体通信中的一个进一步包含用于推注速率的保持装置。该装置包括流动调节装置，其包括由至少第一元件和第二元件限定的通道，其中第一和第二元件中的至少一个是适于弹性变形的主要可变形元件，以便改变横截面积的通道。此外，该装置包括用于存储和供应流体形式的药物的容器，所述容器包括相对于彼此布置的第一和第二腔室，使得当第一腔室的体积增加时，第二腔室的体积减小。

5. 发明授权

US07517335B2 Device for administering of medication in fluid form 有权
标题翻译：用于以流体形式施用药物的装置
公开(公告)号：US07517335B2
公开(公告)日：2009-04-14
申请号：US10503845
申请日：2003-02-18
申请人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
发明人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
IPC分类号： A61M37/00
CPC分类号： A61M5/16881 , A61M5/141 , A61M5/14244 , A61M5/14276 , A61M5/148 , A61M5/152 , A61M5/16804 , A61M5/16813 , A61M5/16854 , A61M2005/1405 , A61M2205/0244 , A61M2205/0294 , A61M2205/3306 , A61M2205/3331
摘要： An infusion device for continuous infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications farther contains a holding device for bolus rate of infusion for a short period. The device comprises a flow regulating device comprising a passage defined by at least a first element and a second element, wherein at least one of the first and second element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber Increases the volume of the second chamber decreases.
摘要翻译：公开了用于连续输注药物的输注装置，其中输注通过两个单独的流体通信来控制。在每个通过限制装置和阀装置控制的流体连通中的输注是，流体通信中的一个进一步包含用于短时间的推注速率的保持装置。该装置包括流动调节装置，其包括由至少第一元件和第二元件限定的通道，其中第一和第二元件中的至少一个是适于弹性变形的主要可变形元件，以便改变横截面积的通道。此外，该装置包括用于存储和供应流体形式的药物的容器，所述容器包括相对于彼此布置的第一和第二腔室，使得当第一腔室的体积增加时，第二腔室的体积减小。

6. 发明申请

US20050165384A1 Device for administering of medication in gluid form 有权
标题翻译：用于以胶体形式施用药物的装置
公开(公告)号：US20050165384A1
公开(公告)日：2005-07-28
申请号：US10503845
申请日：2003-02-18
申请人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
发明人： Peter Gravesen , Per Brandt Rasmussen , Holger Dirac
IPC分类号： A61M5/00 , A61M5/142 , A61M5/145 , A61M5/168 , A61M39/00 , A61K9/22
CPC分类号： A61M5/16881 , A61M5/141 , A61M5/14244 , A61M5/14276 , A61M5/148 , A61M5/152 , A61M5/16804 , A61M5/16813 , A61M5/16854 , A61M2005/1405 , A61M2205/0244 , A61M2205/0294 , A61M2205/3306 , A61M2205/3331
摘要： An infusion device for continuously infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications further contains a holding device for bolus rate of infusion for a short period. The device comprises a flow regulating device comprising a passage defined by at least a first element and a second element, wherein at least one of the first and second element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber increases the volume of the second chamber decreases.
摘要翻译：公开了一种用于持续输注药物的输注装置，其中输注通过两个单独的流体通信进行控制。在每个通过限制装置和阀装置控制的流体连通中的输注，并且流体通信中的一个进一步包含用于短时间的推注速率的保持装置。该装置包括流动调节装置，其包括由至少第一元件和第二元件限定的通道，其中第一和第二元件中的至少一个是适于弹性变形的主要可变形元件，以便改变横截面积的通道。此外，该装置包括用于存储和供应流体形式的药物的容器，所述容器包括相对于彼此布置的第一和第二腔室，使得当第一腔室的体积增加时，第二腔室的体积减小。

7. 发明授权

US11020526B2 Sprinkler cannula 有权
公开(公告)号：US11020526B2
公开(公告)日：2021-06-01
申请号：US13823236
申请日：2011-09-30
申请人： Holger Dirac , John Myhre Frederiksen , Søren Thorup , Bo L. Justesen
发明人： Holger Dirac , John Myhre Frederiksen , Søren Thorup , Bo L. Justesen
IPC分类号： A61M5/158 , A61M5/32 , A61M25/00 , A61M5/142
摘要： An infusion device (50) incl. a preferably soft cannula (1) configured to be inserted by means of an insertion needle. The cannula has a tubular body member having a proximal end and a subcutaneously placed distal portion having a distal end where the distal portion is provided with an opening (2) allowing a portion of a drug conveyed through the tubular body member to discharge. The cannula further comprise, in the distal portion, a radial opening allowing a portion of a drug conveyed through the tubular body member to discharge.

8. 发明申请

US20120095406A1 Inserter Device 审中-公开
标题翻译：插入器设备
公开(公告)号：US20120095406A1
公开(公告)日：2012-04-19
申请号：US13256291
申请日：2010-03-30
申请人： Steffen Gyrn , Søren Thorup , Holger Dirac , Thomas Heinstrup Vikkelsø
发明人： Steffen Gyrn , Søren Thorup , Holger Dirac , Thomas Heinstrup Vikkelsø
IPC分类号： A61B17/34
CPC分类号： A61M5/158 , A61M2005/1581 , A61M2005/1585 , A61M2205/58
摘要： The present application relates to an inserter device for inserting a medical device subcutaneous Iy which inserter device comprises a housing (1); a cover (2) which is slidably connected to the housing (1); a hub (5) for an insertion needle (4) which can be moved linearly relative to the housing (1) and relative to the cover (2); a primary spring (6) which moves the hub (5) for the insertion needle (4) relative to the cover (2) and which primary spring (6) is configured to pull the hub (5) for the insertion needle (4) either to a forward or to a retracted position wherein the inserter device further comprises means for biasing the primary spring (6) before insertion.
摘要翻译：本申请涉及用于插入医疗设备皮下Iy的插入器装置，该插入器装置包括壳体（1）; 可滑动地连接到壳体（1）的盖（2）; 用于插入针（4）的毂（5），其可以相对于所述壳体（1）并相对于所述盖子（2）线性移动; 相对于盖（2）移动用于插入针（4）的轮毂（5）的主弹簧（6），并且该主弹簧（6）构造成拉动用于插入针（4）的轮毂（5）或者到前进或缩回位置，其中插入器装置还包括用于在插入之前偏压主弹簧（6）的装置。

9. 发明申请

US20130245555A1 Sprinkler Cannula 审中-公开
标题翻译：喷头插管
公开(公告)号：US20130245555A1
公开(公告)日：2013-09-19
申请号：US13823236
申请日：2011-09-30
申请人： Holger Dirac , John Myhre Frederiksen , Søren Thorup , Bo L. Justesen
发明人： Holger Dirac , John Myhre Frederiksen , Søren Thorup , Bo L. Justesen
IPC分类号： A61M5/158
CPC分类号： A61M5/158 , A61M5/3291 , A61M2005/1586
摘要： An infusion device (50) incl. a preferably soft cannula (1) configured to be inserted by means of an insertion needle. The cannula has a tubular body member having a proximal end and a subcutaneously placed distal portion having a distal end where the distal portion is provided with an opening (2) allowing a portion of a drug conveyed through the tubular body member to discharge. The cannula further comprise, in the distal portion, a radial opening allowing a portion of a drug conveyed through the tubular body member to discharge.
摘要翻译：输液装置（50）构造成通过插入针插入的优选软套管（1）。套管具有管状本体构件，其具有近端和皮下放置的远侧部分，其具有远端，远端部分设置有允许通过管状本体构件输送的药物的一部分排出的开口（2）。套管还包括在远侧部分中的径向开口，允许通过管状本体构件输送的药物的一部分排出。

10. 发明申请

US20100209300A1 ANALYSIS SYSTEM WITH A REMOTE ANALYSING UNIT 审中-公开
标题翻译：具有远程分析单元的分析系统
公开(公告)号：US20100209300A1
公开(公告)日：2010-08-19
申请号：US12524032
申请日：2008-01-25
申请人： Holger Dirac , Karsten Dupont Nielsen , Jim Radmer , Jesper Peter Windum , Thorkild Ahm
发明人： Holger Dirac , Karsten Dupont Nielsen , Jim Radmer , Jesper Peter Windum , Thorkild Ahm
IPC分类号： G01N21/00 , G01N33/00
CPC分类号： A61B5/14503 , A61B5/14528 , A61B5/14532 , A61B5/1459
摘要： A system for analysing a fluid, the system comprising a base station, an analysing unit being remote from the base station, and a substance collecting device being remote both from the base station and from the analysing unit, a first fluid communication link for communicating fluid between the base station and the analysing unit, and a second fluid communication link for communicating fluid between the analysing unit and the substance collecting device, wherein the analysing unit comprises sensing means adapted to provide data representing a content of a substance in the fluid and wherein the base station comprises data processing means being adapted to process the data to provide information regarding the content of the substance in the fluid.
摘要翻译：一种用于分析流体的系统，所述系统包括基站，远离所述基站的分析单元和远离所述基站和所述分析单元的物质收集装置，用于连通流体的第一流体连通链路以及用于在所述分析单元和所述物质收集装置之间连通流体的第二流体连通链路，其中所述分析单元包括适于提供表示流体中物质含量的数据的感测装置，其中，基站包括数据处理装置，其适于处理数据以提供关于流体中物质的内容的信息。

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