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1. 发明申请

US20120141555A1 Compound and device for treating bone and/or cartilage defects 失效
标题翻译：用于治疗骨和/或软骨缺陷的复合物和装置
公开(公告)号：US20120141555A1
公开(公告)日：2012-06-07
申请号：US13357182
申请日：2012-01-24
申请人： Arne Briest
发明人： Arne Briest
IPC分类号： A61K38/18 , A61K9/00 , A61K33/42 , A61P19/00
CPC分类号： A61L27/227 , A61K38/1866 , A61K38/1875 , A61K38/39 , A61L27/24 , A61K2300/00
摘要： The present invention relates to compositions devices and methods for treating bone and/or cartilage defects, and a method for manufacturing such a composition or device. In a certain embodiment, the invention provides a device and/or composition for treating bone and/or cartilage defects, having at least one collagen, for example of animal origin, and further containing at least one substance having an osteo-inductive or chondro-inductive activity, at least one differentiation and/or growth factor having osteo-stimulative and/or chondro-stimulative effect, and at least one filling material, in which the composition is in the form of a lyophil.
摘要翻译：本发明涉及用于治疗骨和/或软骨缺陷的组合物装置和方法，以及制造这种组合物或装置的方法。在某个实施方案中，本发明提供了用于治疗骨和/或软骨缺陷的装置和/或组合物，其具有至少一种胶原，例如动物来源，并且还含有至少一种具有骨诱导性或软骨型的物质，诱导活性，至少一种具有骨刺激和/或软骨刺激作用的分化和/或生长因子，以及至少一种填充材料，其中所述组合物为冻干物形式。

2. 发明申请

US20120116151A1 DEVICE FOR PREVENTING INCONTINENCE 审中-公开
标题翻译：防止不正当的手段
公开(公告)号：US20120116151A1
公开(公告)日：2012-05-10
申请号：US13261097
申请日：2010-06-22
申请人： Arne BRIEST
发明人： Arne BRIEST
IPC分类号： A61F2/04
CPC分类号： A61F2/004 , A61B17/12099 , A61B17/12136 , A61B2017/00805 , A61F2002/047
摘要： The invention relates to a device for preventing incontinence, having a tube-shaped body (3; 129; 203) comprising a first longitudinal guide element (7; 143; 207) in the interior thereof. A hose-like retaining element connects to the tube-shaped body (3), comprising a second longitudinal guide element (13; 113; 213) in the interior thereof. Said second guide element (13; 113; 213) opens in the axial direction into a termination on the side thereof opposite the tube-shaped body (3). The hose-like retaining element is implemented as a reversible stretchable and collapsible metal mesh (23) comprising a polymer coating (25).
摘要翻译：本发明涉及一种用于防止失禁的装置，其具有在其内部包括第一纵向引导元件（7; 143; 207）的管状主体（3; 129; 203）。软管状保持元件连接到管状体（3），其包括在其内部的第二纵向引导元件（13; 113; 213）。所述第二引导元件（13; 113; 213）在轴向方向上开放成与管状主体（3）相对的一侧的终端。软管状保持元件被实施为包括聚合物涂层（25）的可逆拉伸和可折叠的金属网（23）。

3. 发明申请

US20090017093A1 GELATINOUS MATERIAL FOR FILLING BONE AND/OR CARTILAGE DEFECTS 审中-公开
标题翻译：用于填充骨和/或牙齿缺陷的凝胶材料
公开(公告)号：US20090017093A1
公开(公告)日：2009-01-15
申请号：US11722528
申请日：2005-12-22
申请人： Marco Springer , Arne Briest
发明人： Marco Springer , Arne Briest
IPC分类号： A61K9/00
CPC分类号： A61L27/52 , A61L27/24 , A61L27/54 , A61L2300/406 , A61L2300/414 , A61L2300/416 , A61L2300/426 , A61L2300/802
摘要： Disclosed is a goal gel-type material for filling bone and/or cartilage defects. Said gel-type material comprises at least one gelatinizing component and collagen in at least one liquid dispersing agent. The collagen contains an active substance complex. Preferably, the inventive material is provided with osteoconductive and osteoinductive properties.
摘要翻译：公开了用于填充骨和/或软骨缺陷的目标凝胶型材料。所述凝胶型材料在至少一种液体分散剂中包含至少一种胶凝组分和胶原蛋白。胶原蛋白含有活性物质复合物。优选地，本发明的材料具有骨传导和骨诱导性质。

4. 发明申请

US20090216336A1 BIORESORBABLE, MINERALISED MATERIAL FOR FILLING OSSEOUS DEFECTS 审中-公开
标题翻译：用于填充麻醉缺陷的可生物降解的矿物质
公开(公告)号：US20090216336A1
公开(公告)日：2009-08-27
申请号：US11719864
申请日：2005-11-22
申请人： Marco Springer , Arne Briest
发明人： Marco Springer , Arne Briest
IPC分类号： A61F2/28 , C07K14/78 , A61K47/42 , A61P19/00 , B29C35/16
CPC分类号： A61L27/24 , A61L27/32 , A61L2430/02 , C08L89/02
摘要： A bioresorbable and mineralized material for filling osseous defects includes a native and/or renatured collagen matrix of congregated collagen chains, in which essentially only a surface of the congregated collagen chains is mineralized. A shaped article for filling osseous defects includes such a material. A method for producing a shaped article for filling osseous defects from a liquid medium, includes the steps of deposition of a mineral substance, preferably from its dissolved ionogenic components, on a collagen matrix, precipitation of the mineralized collagen matrix, separation of the mineralized collagen matrix, transfer of the mineralized collagen matrix to a suspension, transfer of the suspension to a mold defining the shaped article, and freeze-drying of the suspension in the mold.
摘要翻译：用于填充骨缺损的生物可吸收和矿化的材料包括聚集的胶原链的天然和/或复性胶原基质，其中基本上只有聚集的胶原链的表面被矿化。用于填充骨缺损的成形制品包括这种材料。一种用于从液体介质填充骨缺损的成形制品的方法，包括以下步骤：将矿物质，优选其溶解的离子发生成分沉积在胶原基质上，沉淀矿化胶原基质，分离矿化胶原基质，将矿化的胶原基质转移到悬浮液中，将悬浮液转移到限定成型制品的模具中，以及将模具中的悬浮液冷冻干燥。

5. 发明申请

US20090022773A1 POROUS AND BIOCOMPATIBLE CARRIER MATERIAL FOR TREATING BONE AND/OR CARTILAGE DEFECTS 审中-公开
标题翻译：用于治疗骨质疏松和/或治疗缺陷的多孔和生物活性载体材料
公开(公告)号：US20090022773A1
公开(公告)日：2009-01-22
申请号：US12095342
申请日：2006-12-01
申请人： Marco Springer , Arne Briest
发明人： Marco Springer , Arne Briest
IPC分类号： A61K35/32 , A61F2/28 , A61P19/00
CPC分类号： A61L27/56 , A61L27/24 , A61L27/54 , A61L2300/412 , A61L2300/802
摘要： A porous and biocompatible carrier material for treating bone and/or cartilage defects, including a collagen of animal origin that has an active substance complex.
摘要翻译：一种用于治疗骨和/或软骨缺陷的多孔和生物相容的载体材料，包括具有活性物质复合物的动物来源的胶原蛋白。

6. 发明授权

US08506514B2 System for regulating intracranial pressure 有权
标题翻译：颅内压调节系统
公开(公告)号：US08506514B2
公开(公告)日：2013-08-13
申请号：US13054309
申请日：2009-07-14
申请人： Hans Joergen Pedersen , Arne Briest
发明人： Hans Joergen Pedersen , Arne Briest
IPC分类号： A61M37/00
CPC分类号： A61M27/006 , A61B5/031 , A61B5/076 , A61B5/103 , A61B5/1116 , A61B5/4528 , A61B5/6864 , A61B5/6868 , A61B2560/0219 , A61B2562/0247 , A61M2205/3507 , A61M2210/0693
摘要： The present invention relates to a method and system to regulate pressure in an object, and is especially suitable for regulating intracranial pressure in people suffering from hydrocephalus. The system includes the measurement of physical parameters other than the pressure to be regulated, especially the present position of the object, such as the inclination.
摘要翻译：本发明涉及一种调节物体压力的方法和系统，特别适用于调节患有脑积水的人的颅内压。该系统包括除了要调节的压力以外的物理参数的测量，特别是对象的当前位置，例如倾斜度。

7. 发明申请

US20100028404A1 Compound and device for treating bone and/or cartilage defects 失效
标题翻译：用于治疗骨和/或软骨缺陷的复合物和装置
公开(公告)号：US20100028404A1
公开(公告)日：2010-02-04
申请号：US12554940
申请日：2009-09-07
申请人： Arne Briest
发明人： Arne Briest
IPC分类号： A61F2/00 , A61K38/39 , A61K38/16 , A61K9/50
CPC分类号： A61L27/227 , A61K38/1866 , A61K38/1875 , A61K38/39 , A61L27/24 , A61K2300/00
摘要： The present invention relates to compositions devices and methods for treating bone and/or cartilage defects, and a method for manufacturing such a composition or device. In a certain embodiment, the invention provides a device and/or composition for treating bone and/or cartilage defects, having at least one collagen, for example of animal origin, and further containing at least one substance having an osteo-inductive or chondro-inductive activity, at least one differentiation and/or growth factor having osteo-stimulative and/or chondro-stimulative effect, and at least one filling material, in which the composition is in the form of a lyophil.
摘要翻译：本发明涉及用于治疗骨和/或软骨缺陷的组合物装置和方法，以及制造这种组合物或装置的方法。在某个实施方案中，本发明提供了用于治疗骨和/或软骨缺陷的装置和/或组合物，其具有至少一种胶原，例如动物来源，并且还含有至少一种具有骨诱导性或软骨型的物质，诱导活性，至少一种具有骨刺激和/或软骨刺激作用的分化和/或生长因子，以及至少一种填充材料，其中所述组合物为冻干物形式。

8. 发明申请

US20080140199A1 Impantable Body for Spinal Fusion 审中-公开
标题翻译：脊柱融合不易身体
公开(公告)号：US20080140199A1
公开(公告)日：2008-06-12
申请号：US11572436
申请日：2005-07-16
申请人： Arne Briest
发明人： Arne Briest
IPC分类号： A61F2/44
CPC分类号： A61F2/4455 , A61F2/0095 , A61F2002/2817 , A61F2002/30062 , A61F2002/30082 , A61F2002/30131 , A61F2002/30171 , A61F2002/30179 , A61F2002/302 , A61F2002/30291 , A61F2002/30677 , A61F2002/30828 , A61F2002/4475 , A61F2210/0004 , A61F2210/0095 , A61F2230/0013 , A61F2230/005 , A61F2230/0058 , A61F2230/0065 , A61F2230/0091 , A61F2310/00017 , A61F2310/00047 , A61F2310/00083 , A61F2310/0097 , A61F2310/00976 , A61L27/042 , A61L27/047 , A61L27/58
摘要： An implantable body for intersomatic fusion (spinal fusion) is disclosed, made from a bioresorbable, metallic material. Said metallic material preferably contains magnesium or iron as main component. The material is particularly a magnesium alloy or an iron alloy.
摘要翻译：公开了由生物可再吸收的金属材料制成的用于腔内融合（脊柱融合）的可植入体。所述金属材料优选含有镁或铁作为主要成分。该材料特别是镁合金或铁合金。

9. 发明授权

US08586070B2 Composition and device for treating bone and/or cartilage defects 失效
标题翻译：用于治疗骨和/或软骨缺陷的组合物和装置
公开(公告)号：US08586070B2
公开(公告)日：2013-11-19
申请号：US13357182
申请日：2012-01-24
申请人： Arne Briest
发明人： Arne Briest
IPC分类号： A61K38/00 , A61K38/16 , A61K38/17 , A61K38/18 , A61K38/30 , A61K38/39
CPC分类号： A61L27/227 , A61K38/1866 , A61K38/1875 , A61K38/39 , A61L27/24 , A61K2300/00
摘要： The present invention relates to compositions devices and methods for treating bone and/or cartilage defects, and a method for manufacturing such a composition or device. In a certain embodiment, the invention provides a device and/or composition for treating bone and/or cartilage defects, having at least one collagen, for example of animal origin, and further containing at least one substance having an osteo-inductive or chondro-inductive activity, at least one differentiation and/or growth factor having osteo-stimulative and/or chondro-stimulative effect, and at least one filling material, in which the composition is in the form of a lyophil.
摘要翻译：本发明涉及用于治疗骨和/或软骨缺陷的组合物装置和方法，以及制造这种组合物或装置的方法。在某个实施方案中，本发明提供了用于治疗骨和/或软骨缺陷的装置和/或组合物，其具有至少一种胶原，例如动物来源，并且还含有至少一种具有骨诱导性或软骨型的物质，诱导活性，至少一种具有骨刺激和/或软骨刺激作用的分化和/或生长因子，以及至少一种填充材料，其中所述组合物为冻干物形式。

10. 发明授权

US08114428B2 Methods for manufacturing a composition for treating bone and/or cartilage defects 失效
标题翻译：用于制造用于治疗骨和/或软骨缺陷的组合物的方法
公开(公告)号：US08114428B2
公开(公告)日：2012-02-14
申请号：US12554940
申请日：2009-09-07
申请人： Arne Briest
发明人： Arne Briest
IPC分类号： A61K38/00 , A61K38/16 , A61K38/17 , A61K38/18 , A61K38/30 , A61K38/39
CPC分类号： A61L27/227 , A61K38/1866 , A61K38/1875 , A61K38/39 , A61L27/24 , A61K2300/00
摘要： The present invention relates to compositions devices and methods for treating bone and/or cartilage defects, and a method for manufacturing such a composition or device. In a certain embodiment, the invention provides a device and/or composition for treating bone and/or cartilage defects, having at least one collagen, for example of animal origin, and further containing at least one substance having an osteo-inductive or chondro-inductive activity, at least one differentiation and/or growth factor having osteo-stimulative and/or chondro-stimulative effect, and at least one filling material, in which the composition is in the form of a lyophil.
摘要翻译：本发明涉及用于治疗骨和/或软骨缺陷的组合物装置和方法，以及制造这种组合物或装置的方法。在某个实施方案中，本发明提供了用于治疗骨和/或软骨缺陷的装置和/或组合物，其具有至少一种胶原，例如动物来源，并且还含有至少一种具有骨诱导性或软骨型的物质，诱导活性，至少一种具有骨刺激和/或软骨刺激作用的分化和/或生长因子，以及至少一种填充材料，其中所述组合物为冻干物形式。

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