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    • 7. 发明授权
    • Phosphor layer for radiation image conversion panel
    • 荧光层用于辐射图像转换面板
    • US06641858B1
    • 2003-11-04
    • US09588571
    • 2000-06-07
    • Hideki SuzukiKatsuhiro Kohda
    • Hideki SuzukiKatsuhiro Kohda
    • B05D506
    • G21K4/00C09K11/02C09K11/025C09K11/7733G21K2004/08
    • A method of preparing a phosphor layer coating solution of a radiation image conversion panel is provided, in which, at least a phosphor, a binder, a cross-linking agent which cross-links the binder by being heated, and a solvent are constituent components of the phosphor layer coating solution. The method includes a phosphor dispersing step in which the constituent components other than the cross-linking agent are mixed and stirred to disperse the phosphor such that a phosphor dispersion is prepared, a cooling step in which the phosphor dispersion prepared in the phosphor dispersing step is cooled, and a cross-linking agent adding step in which the cross-linking agent is added to the phosphor dispersion cooled in the cooling step and the dispersion is stirred such that the cross-linking agent is thoroughly mixed therewith.
    • 提供一种制备放射线图像转换面板的荧光体层涂布溶液的方法,其中至少含有荧光体,粘合剂,通过加热使粘合剂交联的交联剂,溶剂是构成成分 的荧光体层涂布溶液。 该方法包括荧光体分散步骤,其中将交联剂以外的组成成分混合并搅拌以分散荧光体,使得制备荧光体分散体;制备步骤,其中在荧光体分散步骤中制备的荧光体分散体为 将交联剂添加到在冷却工序中冷却的荧光体分散体中并进行搅拌,使交联剂充分混合的交联剂添加工序。
    • 8. 发明申请
    • POLYMER-ACTIVE AGENT CONJUGATES
    • 聚合物活性剂共混物
    • US20130344023A1
    • 2013-12-26
    • US13981235
    • 2012-01-11
    • Michel WathierHideki Suzuki
    • Michel WathierHideki Suzuki
    • A61K47/48
    • A61K47/48176A61K47/58
    • A polymer includes at least one monomeric unit represented by Formula I, II, or III: where X is CH2 or O; R1 is H, COOR2, COCH3, CONHR2, OR2 or SR2; L is a bond or a linker group; AA is a group derived from an active agent; each R2 is independently H, a cation, an alkyl, an alkenyl, an alkynyl, COCH3, CH2CH2OH, CH2CH2OR3, an amino acid, a small peptide, a large peptide, enzyme, protein, growth factor, cytokine, antibody, single chain antibody, antibody fragment, COCCH3═CH2, COCH═CH2, CH2CO2H, CH2CH2CO2H, CH2CH2SH, CH2CH2SR3 or (CH2CH2O)n′R4; n′ is an integer from 1 to 2000; each R3 is independently trityl, 4-methyltrityl or 2 pyridyl; each R4 is independently H, an alkyl, an alkenyl, an alkynyl, COCCH3═CH2, COCH═CH2, CH2CHO, CH2CH2CHO, CO2H, CO2R5, CH2CO2H, CH2CH2CO2H, CH2NH2, CH2NHR5, CH2N(R5)2, CH2CH2NH2, CH2CH2NHR, CH2CH2N(R5)2, SH, CH2CO2R5, or CH2CH2CO2R5; and each R5 is independently maleimide, a cation, an amino acid, a small peptide, a large peptide, protein, enzyme, growth factor, cytokine, antibody, single chain antibody, phosphate, sulfate, choline, or an activated ester.
    • 聚合物包括由式I,II或III表示的至少一个单体单元:其中X是CH 2或O; R1是H,COOR2,COCH3,CONHR2,OR2或SR2; L是键或连接基; AA是一种衍生自活性剂的基团; 每个R 2独立地是H,阳离子,烷基,烯基,炔基,COCH 3,CH 2 CH 2 OH,CH 2 CH 2OR 3,氨基酸,小肽,大肽,酶,蛋白质,生长因子,细胞因子,抗体,单链抗体 ,抗体片段,COCCH3 = CH2,COCH = CH2,CH2CO2H,CH2CH2CO2H,CH2CH2SH,CH2CH2SR3或(CH2CH2O)n'R4; n'是从1到2000的整数; 每个R 3独立地是三苯甲基,4-甲基三苯甲基或2-吡啶基; 每个R 4独立地是H,烷基,烯基,炔基,COCCH 3 = CH 2,COCH = CH 2,CH 2 CHO,CH 2 CH 2 CHO,CO 2 H,CO 2 R 5,CH 2 CO 2 H,CH 2 CH 2 CO 2 H,CH 2 NH 2,CH 2 NHR 5,CH 2 N(R 5)2,CH 2 CH 2 NH 2,CH 2 CH 2 NHR,CH 2 CH 2 N (R5)2,SH,CH2CO2R5或CH2CH2CO2R5; 每个R 5独立地为马来酰亚胺,阳离子,氨基酸,小肽,大肽,蛋白质,酶,生长因子,细胞因子,抗体,单链抗体,磷酸盐,硫酸盐,胆碱或活化酯。