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1. 发明授权

US5709703A Stent delivery device and method for manufacturing same 失效
标题翻译：支架输送装置及其制造方法
公开(公告)号：US5709703A
公开(公告)日：1998-01-20
申请号：US744036
申请日：1996-11-05
申请人： Goran Lukic , Marc Gianotti
发明人： Goran Lukic , Marc Gianotti
IPC分类号： A61F2/82 , A61F2/06 , A61F2/84 , A61M25/00 , A61B17/00
CPC分类号： A61F2/95 , A61F2/966 , A61M25/0009
摘要： The stent delivery device has an elongated sheath with a self-expandable stent placed in contracted condition within the distal area of the sheath. An elongated core is arranged in the sheath for relative longitudinal motion between core and sheath, and drive means are arranged between the core and the stent. Scratch protection tubular means comprise a reinforcement ring secured in the sheath and surrounding the distal end portion of the stent when the stent is in contracted condition in the sheath and a tube of thermoformable material heat shrunk over the proximal end portion of the stent and over the core.
摘要翻译：支架输送装置具有细长的护套，其中自扩张支架置于收缩状态下在护套的远端区域内。在芯鞘和护套之间布置细长的芯体以进行相对的纵向运动，驱动装置设置在芯体和支架之间。刮擦保护管状装置包括固定在护套中并且当支架在护套中处于收缩状态时围绕支架的远端部分的加强环，并且热可成型材料管热收缩在支架的近端部分上方核心。

2. 发明申请

US20110270381A1 METHODS AND APPARATUS FOR STENTING COMPRISING ENHANCED EMBOLIC PROTECTION COUPLED WITH IMPROVED PROTECTIONS AGAINST RESTENOSIS AND THROMBUS FORMATION 有权
标题翻译：用于包括增强的保护性保护的改进方法和装置与改进的保护和血栓形成的保护
公开(公告)号：US20110270381A1
公开(公告)日：2011-11-03
申请号：US13089039
申请日：2011-04-18
申请人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf von Oepen
发明人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf von Oepen
IPC分类号： A61F2/82
CPC分类号： A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
摘要： Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
摘要翻译：提供了用于支架置入的装置和方法，其包括附着于多孔生物相容性材料的支架，所述多孔生物相容性材料可渗透内皮细胞向内生长，但不能透过预定尺寸的栓塞。提供优选的支架设计，以及优选的制造技术。还提供了用于血管分支的装置和方法。此外，本发明的实施方案可以包括被配置用于局部递送治疗剂的涂层。预期本发明的实施方案可提供增强的栓塞保护，改善的力分布和改善的再交联性，同时降低再狭窄和血栓形成的风险。

3. 发明授权

US07811314B2 Methods and apparatus for stenting comprising enhanced embolic protection coupled with improved protections against restenosis and thrombus formation 有权
标题翻译：用于支架置入的方法和装置包括增强的栓塞保护以及改进的针对再狭窄和血栓形成的保护
公开(公告)号：US07811314B2
公开(公告)日：2010-10-12
申请号：US11732244
申请日：2007-04-02
申请人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf von Oepen
发明人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf von Oepen
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
摘要： Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
摘要翻译：提供了用于支架置入的装置和方法，其包括附着于多孔生物相容性材料的支架，所述多孔生物相容性材料可渗透内皮细胞向内生长，但不能透过预定尺寸的栓塞。提供优选的支架设计，以及优选的制造技术。还提供了用于血管分支的装置和方法。此外，本发明的实施方案可以包括被配置用于局部递送治疗剂的涂层。预期本发明的实施方案可提供增强的栓塞保护，改善的力分布和改善的再交联性，同时降低再狭窄和血栓形成的风险。

4. 发明授权

US5626602A Catheter with a vascular support 失效
标题翻译：导管与血管支持
公开(公告)号：US5626602A
公开(公告)日：1997-05-06
申请号：US375591
申请日：1995-01-17
申请人： Marc Gianotti , Paul Lehmann
发明人： Marc Gianotti , Paul Lehmann
IPC分类号： A61M25/00 , A61F2/00 , A61F2/06 , A61F2/82 , A61F2/84 , A61F2/88 , A61M25/04 , A61M29/00
CPC分类号： A61F2/88 , A61F2/95 , A61F2/966 , A61F2230/0076 , A61F2250/0098
摘要： A catheter with a radially self-expanding cylindrical vascular support made of a permeable mesh of crossed stiff fibers is disclosed. The catheter has a tubular outer catheter shaft and an inner catheter to which the vascular support is fixed. The tubular outer catheter shaft is axially movable with respect to the inner catheter.
摘要翻译：公开了一种具有径向自膨胀圆柱形血管支架的导管，其由交叉刚性纤维的可渗透网构成。导管具有管状外导管轴和固定血管支架的内导管。管状外导管轴可相对于内导管轴向移动。

5. 发明授权

US07927364B2 Methods and apparatus for stenting comprising enhanced embolic protection coupled with improved protections against restenosis and thrombus formation 有权
公开(公告)号：US07927364B2
公开(公告)日：2011-04-19
申请号：US10859636
申请日：2004-06-03
申请人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf Von Oepen
发明人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf Von Oepen
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
摘要： Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.

6. 发明授权

US06240978B1 Stent and method for manufacturing such a stent 有权
标题翻译：用于制造这种支架的支架和方法
公开(公告)号：US06240978B1
公开(公告)日：2001-06-05
申请号：US09431988
申请日：1999-11-02
申请人： Marc Gianotti
发明人： Marc Gianotti
IPC分类号： B21F3300
CPC分类号： A61F2/90 , A61F2/88 , A61F2002/3011 , A61F2230/0002 , D04C1/06 , D04C3/48 , D10B2403/0241 , D10B2509/06 , Y10T29/49874
摘要： A prosthetic stent with a tubular wall having local inwardly or outwardly formed elevations. Stents having such elevations have a higher mechanical stability if bend according to the curvature of the body vessels to be supported or repaired. Also a method for manufacturing a stent with such elevations is described.
摘要翻译：具有管状壁的假体支架具有局部向内或向外形成的高度。具有这种高度的支架具有较高的机械稳定性，如果根据体容器的曲率进行弯曲以被支撑或修复。还描述了一种用于制造具有这种高度的支架的方法。

7. 发明授权

US5725571A Catheter with a stent 失效
标题翻译：导管与支架
公开(公告)号：US5725571A
公开(公告)日：1998-03-10
申请号：US752273
申请日：1996-11-20
申请人： Christian Imbert , Eugen Hofmann , Marc Gianotti
发明人： Christian Imbert , Eugen Hofmann , Marc Gianotti
IPC分类号： A61M25/00 , A61F2/90 , A61M27/00 , A61F2/06 , A61M29/00
CPC分类号： A61F2/95 , A61F2/90 , A61F2/966
摘要： A catheter with a self-expanding stent of a permeable mesh of stiff intersecting fibers is provided. A tubular outer catheter shaft holds the stent under tension at its distal end and from which the stent can be released for placement. A displaceable inner catheter inside the tubular outer catheter shaft supports the stent axially at its proximal end. In order to release the stent, the outer catheter shaft is retracted with respect to the inner catheter. A process for producing this catheter is also described. The stent is secured by gripping it at its proximal end in such a way that it forms a permeable mesh cone that expands automatically together with the stent and has a radius that increases gradually to the radius of the relaxed stent. The stent is securely anchored on the inner catheter with the help of the mesh cone.
摘要翻译：提供了具有刚性交叉纤维的可渗透网的自膨胀支架的导管。管状外导管轴将支架保持在其远端处的张力处，并且支架可以从该导管释放以放置。管状外导管轴内的位移内导管在其近端轴向支撑支架。为了释放支架，外导管轴相对于内导管缩回。还描述了用于生产该导管的方法。通过在其近端处夹持支架来固定支架，使得其形成与支架一起自动扩张的可渗透的网孔，并且具有逐渐增加到松弛支架的半径的半径。借助于网孔，支架可靠地固定在内导管上。

8. 发明授权

US5607466A Catheter with a stent 失效
标题翻译：导管与支架
公开(公告)号：US5607466A
公开(公告)日：1997-03-04
申请号：US433281
申请日：1995-04-28
申请人： Christian Imbert , Eugen Hofmann , Marc Gianotti
发明人： Christian Imbert , Eugen Hofmann , Marc Gianotti
IPC分类号： A61M25/00 , A61F2/90 , A61M27/00 , A61F2/06 , A61M5/178 , A61M29/00
CPC分类号： A61F2/95 , A61F2/90 , A61F2/966
摘要： A catheter with a self-expanding stent of a permeable mesh of stiff intersecting fibers is provided. A tubular outer catheter shaft holds the stent under tension at its distal end and from which the stent can be released for placement. A displaceable inner catheter inside the tubular outer catheter shaft supports the stent axially at its proximal end. In order to release the stent, the outer catheter shaft is retracted with respect to the inner catheter. A process for producing this catheter is also described. The stent is secured by gripping it at its proximal end in such a way that it forms a permeable mesh cone that expands automatically together with the stent and has a radius that increases gradually to the radius of the relaxed stent. The stent is securely anchored on the inner catheter with the help of the mesh cone.
摘要翻译：提供了具有刚性交叉纤维的可渗透网的自膨胀支架的导管。管状外导管轴将支架保持在其远端处的张力处，并且支架可以从该导管释放以放置。管状外导管轴内部的位移内导管在其近端轴向支撑支架。为了释放支架，外导管轴相对于内导管缩回。还描述了用于生产该导管的方法。通过在其近端处夹持支架来固定支架，使得其形成与支架一起自动扩张的可渗透的网孔，并且具有逐渐增加到松弛支架的半径的半径。借助于网孔，支架可靠地固定在内导管上。

9. 发明授权

US07993303B2 Stiffening support catheter and methods for using the same 有权
标题翻译：加强支撑导管及其使用方法
公开(公告)号：US07993303B2
公开(公告)日：2011-08-09
申请号：US11738384
申请日：2007-04-20
申请人： Randolf Von Oepen , Ian J. Clark , Lorcan Coffey , Thomas Rieth , Richard Newhauser , Travis Yribarren , Marc Gianotti , Bernhard Uihlein
发明人： Randolf Von Oepen , Ian J. Clark , Lorcan Coffey , Thomas Rieth , Richard Newhauser , Travis Yribarren , Marc Gianotti , Bernhard Uihlein
IPC分类号： A61M29/00
CPC分类号： A61M25/0054 , A61M25/0053 , A61M2025/0006 , A61M2025/0025 , A61M2025/0063
摘要： A support catheter that can puncture a heart septum with a guidewire without buckling and that can access difficult to reach arteries such as carotid or renal arteries from the aorta under difficult circumstances is provided. The support catheter comprises a catheter body having a proximal end, a distal end, and an interior wall surface defining a first lumen extending from the proximal end toward the distal end. A second lumen is disposed between the interior wall surface and an outer surface of the catheter body. A plurality of stiffening members is disposed around the second lumen, the plurality of stiffening members being engageable to selectively stiffen the catheter body. In another configuration, the catheter further comprises a second plurality of stiffening members disposed between the first lumen and the second lumen.
摘要翻译：提供了一种支撑导管，其可以用导线刺穿心脏隔膜而没有屈曲，并且可以在困难的情况下进入难以到达主动脉的颈动脉或肾动脉的动脉。支撑导管包括具有近端，远端和限定从近端朝向远端延伸的第一内腔的内壁表面的导管主体。第二管腔设置在内壁表面和导管主体的外表面之间。多个加强构件设置在第二内腔周围，多个加强构件可接合以选择性地加强导管主体。在另一种构造中，导管还包括设置在第一腔和第二腔之间的第二多个加强构件。

10. 发明授权

US07927365B2 Methods and apparatus for stenting comprising enhanced embolic protection coupled with improved protections against restenosis and thrombus formation 有权
标题翻译：用于支架置入的方法和装置包括增强的栓塞保护以及改进的针对再狭窄和血栓形成的保护
公开(公告)号：US07927365B2
公开(公告)日：2011-04-19
申请号：US11731820
申请日：2007-03-29
申请人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf Von Oepen
发明人： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf Von Oepen
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
摘要： Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
摘要翻译：提供了用于支架置入的装置和方法，其包括附着于多孔生物相容性材料的支架，所述多孔生物相容性材料可渗透内皮细胞向内生长，但不能透过预定尺寸的栓塞。提供优选的支架设计，以及优选的制造技术。还提供了用于血管分支的装置和方法。此外，本发明的实施方案可以包括被配置用于局部递送治疗剂的涂层。预期本发明的实施方案可提供增强的栓塞保护，改善的力分布和改善的再交联性，同时降低再狭窄和血栓形成的风险。

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