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    • 5. 发明授权
    • Apparatus and method for determining tissue characteristics
    • 用于确定组织特征的装置和方法
    • US06590651B1
    • 2003-07-08
    • US09700538
    • 2000-11-16
    • Shabbir BambotMark L. FaupelGlenn Steven Arche
    • Shabbir BambotMark L. FaupelGlenn Steven Arche
    • G01N2100
    • A61B5/0071A61B5/0084G01N21/474G01N21/49G01N21/6486G01N2021/6484
    • An apparatus and method embodying the invention include utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue (50). An instrument embodying the invention includes a plurality of detection devices (54) that are arranged in a predetermined pattern on a tissue contacting face of the instrument. The face of the instrument is located adjacent the target tissue (50), and a plurality of tissue characteristic measurement are simultaneously conducted. The detection devices (54) are moved to a new position, preferably without moving the tissue contacting face, and a second plurality of tissue characteristic measurements are simultaneously conducted. By conducting a series of measurements cycles in this manner, the ultimate resolution of the device is increased, while still obtaining a given resolution, which reduces potential cross-talk errors. Further, a plurality of tissue characteristics are simultaneously obtained from locations spaced across the target tissue (50) during each measurement cycle.
    • 体现本发明的装置和方法包括利用具有有限数量的询问装置的装置来在目标组织(50)上完成大量的测量。 实施本发明的仪器包括在仪器的组织接触面上以预定图案布置的多个检测装置(54)。 仪器的表面位于目标组织(50)附近,同时进行多个组织特征测量。 检测装置(54)移动到新的位置,优选地不移动组织接触面,同时进行第二组织特征测量。 通过以这种方式进行一系列测量周期,设备的最终分辨率得到提高,同时仍然获得给定的分辨率,这降低了潜在的串扰误差。 此外,在每个测量周期期间,跨越目标组织(50)间隔开的位置同时获得多个组织特征。
    • 6. 发明授权
    • Apparatus and method for determining tissue characteristics
    • 用于确定组织特征的装置和方法
    • US07006220B2
    • 2006-02-28
    • US10611917
    • 2003-07-03
    • Shabbir BambotMark L. FaupelGlenn Steven Arche
    • Shabbir BambotMark L. FaupelGlenn Steven Arche
    • G01N21/00A61B1/06
    • A61B5/0071A61B5/0084G01N21/474G01N21/49G01N21/6486G01N2021/6484
    • An apparatus and method embodying the invention including utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue. An instrument embodying the invention includes a plurality of detection devices that are arranged in a predetermined pattern on a tissue contacting face of the instrument. The face of the instrument is located adjacent the target tissue, and a plurality of tissue characteristic measurement are simultaneously conducted. The detection devices are moved to a new position, preferably without moving the tissue contacting face, and a second plurality of tissue characteristic measurements are simultaneously conducted. By conducting a series of measurement cycles in this manner, the ultimate resolution of the device is increased, while still obtaining a given resolution, which reduces potential cross-talk errors. Further, a plurality of tissue characteristics are simultaneously obtained from locations spaced across the target tissue during each measurement cycle.
    • 实施本发明的装置和方法包括利用具有有限数量的询问装置的装置来在目标组织上完成大量的测量。 实施本发明的仪器包括以预定图案布置在仪器的组织接触面上的多个检测装置。 仪器的表面位于目标组织附近,并且同时进行多个组织特征测量。 检测装置移动到新的位置,优选地不移动组织接触面,同时进行第二组织特征测量。 通过以这种方式进行一系列测量循环,设备的最终分辨率提高,同时仍然获得给定的分辨率,这降低了潜在的串扰误差。 此外,在每个测量周期期间,通过目标组织间隔开的位置同时获得多个组织特征。
    • 7. 发明授权
    • Disposable calibration target
    • 一次性校准目标
    • US06192734B1
    • 2001-02-27
    • US09286649
    • 1999-04-06
    • Robert RothfritzScott KerrGlenn Steven ArcheScott KelloggGregory J. NewmanMark A. SamuelsRichard Lachlan Fowler
    • Robert RothfritzScott KerrGlenn Steven ArcheScott KelloggGregory J. NewmanMark A. SamuelsRichard Lachlan Fowler
    • A61B500
    • A61B5/0059A61B5/1495A61B2560/0233G01J5/02G01J5/021G01J5/04G01J5/048G01J5/522G01N21/276G01N21/278G01N21/645G01N2201/0221
    • A combined infection shield and calibration or reference target for use with a measuring instrument includes a removable calibration/reference layer. The removable calibration/reference layer has predetermined optical characteristics that can be utilized to calibrate or reference the instrument. When the calibration/reference layer is removed from the remaining portions of the device, the portion of the calibration/reference layer having the predetermined optical characteristics is irrevocably altered such that the calibration/reference layer cannot be reused. The combined infection shield and target may be attached to a shield holder, which in turn is attached to an instrument. Alternatively, the infection shield and target may be attached directly to an instrument. The target may include a calibration/reference layer having a reduced strength portion which causes the target to tear or separate in a predetermined manner. Also, a double-sided adhesive layer with a gap may be used to attach the target to the remaining portions of the device, wherein the gap is arranged in a predetermined orientation with the reduced strength portion to aid tearing or separation of the target in a predetermined manner. The device may also include a cutter for causing the calibration/reference layer to tear or separate in a predetermined manner when the calibration/reference layer is removed from other portions of the device.
    • 与测量仪器一起使用的组合感染屏蔽和校准或参考目标包括可移除的校准/参考层。 可拆卸的校准/参考层具有可用于校准或参考仪器的预定光学特性。 当校准/参考层从设备的其余部分移除时,具有预定光学特性的校准/参考层的部分不可逆转地改变,使得校准/参考层不能被重复使用。 组合的感染屏蔽物和靶标可以附着到屏蔽保持器上,屏蔽保持器又连接到仪器上。 或者,感染屏蔽物和靶标可以直接附着在仪器上。 目标可以包括具有减小的强度部分的校准/参考层,其导致靶以预定方式撕裂或分离。 此外,可以使用具有间隙的双面粘合剂层将目标附着到装置的其余部分,其中间隙以减小的强度部分以预定取向布置,以有助于撕裂或分离靶材 预先确定的方式。 当校准/参考层从设备的其它部分移除时,该装置还可包括用于使校准/参考层以预定方式撕开或分离的切割器。
    • 8. 发明授权
    • Apparatus and method for determining tissue characteristics
    • 用于确定组织特征的装置和方法
    • US07301629B2
    • 2007-11-27
    • US11351054
    • 2006-02-09
    • Shabbir BambotMark L. FaupelGlenn Steven Arche
    • Shabbir BambotMark L. FaupelGlenn Steven Arche
    • G01N21/00
    • A61B5/0071A61B5/0084G01N21/474G01N21/49G01N21/6486G01N2021/6484
    • An apparatus and method embodying the invention include utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue (50). An instrument embodying the invention includes a plurality of detection devices (54) that are arranged in a predetermined pattern on a tissue contacting face of the instrument. The face of the instrument is located adjacent the target tissue (50), and a plurality of tissue characteristic measurement are simultaneously conducted. The detection devices (54) are moved to a new position, preferably without moving the tissue contacting face, and a second plurality of tissue characteristic measurements are simultaneously conducted. By conducting a series of measurements cycles in this manner, the ultimate resolution of the device is increased, while still obtaining a given resolution, which reduces potential cross-talk errors. Further, a plurality of tissue characteristics are simultaneously obtained from locations spaced across the target tissue (50) during each measurement cycle.
    • 体现本发明的装置和方法包括利用具有有限数量的询问装置的装置来在目标组织(50)上完成大量的测量。 实施本发明的仪器包括在仪器的组织接触面上以预定图案布置的多个检测装置(54)。 仪器的表面位于目标组织(50)附近,同时进行多个组织特征测量。 检测装置(54)移动到新的位置,优选地不移动组织接触面,同时进行第二组织特征测量。 通过以这种方式进行一系列测量周期,设备的最终分辨率得到提高,同时仍然获得给定的分辨率,这降低了潜在的串扰误差。 此外,在每个测量周期期间,跨越目标组织(50)间隔开的位置同时获得多个组织特征。
    • 10. 发明授权
    • Disposable calibration target
    • 一次性校准目标
    • US5924981A
    • 1999-07-20
    • US54490
    • 1998-04-03
    • Robert RothfritzScott KerrGlenn Steven ArcheScott KelloggGregory J. NewmanMark A. SamuelsRichard Lachlan Fowler
    • Robert RothfritzScott KerrGlenn Steven ArcheScott KelloggGregory J. NewmanMark A. SamuelsRichard Lachlan Fowler
    • A61B5/00A61B6/00G01B9/02G01D18/00G01N3/62G01N21/27G01N21/64
    • A61B5/0059A61B5/1495G01J5/02G01J5/021G01J5/04G01J5/048G01J5/522G01N21/276G01N21/278G01N21/645A61B2560/0233G01N2201/0221
    • A combined infection shield and calibration or reference target for use with a measuring instrument includes a removable calibration/reference layer. The removable calibration/reference layer has predetermined optical characteristics that can be utilized to calibrate or reference the instrument. When the calibration/reference layer is removed from the remaining portions of the device, the portion of the calibration/reference layer having the predetermined optical characteristics is irrevocably altered such that the calibration/reference layer cannot be reused. The combined infection shield and target may be attached to a shield holder, which in turn is attached to an instrument. Alternatively, the infection shield and target may be attached directly to an instrument. The target may include a calibration/reference layer having a reduced strength portion which causes the target to tear or separate in a predetermined manner. Also, a double-sided adhesive layer with a gap may be used to attach the target to the remaining portions of the device, wherein the gap is arranged in a predetermined orientation with the reduced strength portion to aid tearing or separation of the target in a predetermined manner. The device may also include a cutter for causing the calibration/reference layer to tear or separate in a predetermined manner when the calibration/reference layer is removed from other portions of the device.
    • 与测量仪器一起使用的组合感染屏蔽和校准或参考目标包括可移除的校准/参考层。 可拆卸的校准/参考层具有可用于校准或参考仪器的预定光学特性。 当校准/参考层从设备的其余部分移除时,具有预定光学特性的校准/参考层的部分不可逆转地改变,使得校准/参考层不能被重复使用。 组合的感染屏蔽物和靶标可以附着到屏蔽保持器上,屏蔽保持器又连接到仪器上。 或者,感染屏蔽物和靶标可以直接附着在仪器上。 目标可以包括具有减小的强度部分的校准/参考层,其导致靶以预定方式撕裂或分离。 此外,可以使用具有间隙的双面粘合剂层将目标附着到装置的其余部分,其中间隙以减小的强度部分以预定取向布置,以有助于撕裂或分离靶材 预先确定的方式。 当校准/参考层从设备的其它部分移除时,该装置还可包括用于使校准/参考层以预定方式撕开或分离的切割器。