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1. 发明申请

US20070025509A1 4-dimensional digital tomosynthesis and its applications in radiation therapy 有权
标题翻译： 4维数字断层合成及其在放射治疗中的应用
公开(公告)号：US20070025509A1
公开(公告)日：2007-02-01
申请号：US11181339
申请日：2005-07-13
申请人： Geordi Pang , Ali Bani-Hashemi , John Rowlands
发明人： Geordi Pang , Ali Bani-Hashemi , John Rowlands
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/025 , A61B6/5288 , A61B6/583 , A61N5/1037 , A61N2005/1061
摘要： A 4-dimensional digital tomosynthesis system includes an x-ray source, an x-ray detector and a processor. The x-ray source is suitable for emitting x-ray beams to an object with a periodic motion. The periodic motion is divided into (n+1) time intervals, n being a positive integer. Each of the (n+1) time intervals is associated with a time instance ti, i=0, 1, 2, . . . , n. The x-ray detector is coupled to the x-ray source for acquiring projection radiographs of the object at each time instance ti for each scan angle based on the x-ray beams. The processor is communicatively coupled to the x-ray source and the x-ray detector for controlling the x-ray source and processing data received from the x-ray detector such that all projection radiographs acquired from all scan angles for each time instance ti are reconstructed and (n+1) sets of cross sections of the object are obtained. The cross section is either a coronal cross section or a sagittal cross section. Each of the (n+1) sets of cross sections is for a different time instance ti.
摘要翻译： 4维数字断层合成系统包括x射线源，x射线检测器和处理器。 x射线源适合于向具有周期运动的物体发射X射线束。周期运动分为（n + 1）个时间间隔，n为正整数。（n + 1）个时间间隔中的每一个与时间实例t i i i i，i = 0,1,2，...相关联。。。，n。 x射线检测器耦合到x射线源，用于基于X射线束针对每个扫描角度的每个时间实例t 1采集物体的投影射线照片。处理器通信地耦合到x射线源和X射线检测器，用于控制x射线源和从x射线检测器接收的处理数据，使得对于每个时间t t从所有扫描角度获取的所有投影射线照片， SUB＆gt; i＆lt; i＆gt;被重构，并且获得对象的（n + 1）个横截面集合。横截面是冠状截面或矢状截面。第（n + 1）组横截面中的每一个都是用于不同的时间实例t 。

2. 发明授权

US09789337B2 Combined imaging modalities for radiation treatment planning 有权
公开(公告)号：US09789337B2
公开(公告)日：2017-10-17
申请号：US13269324
申请日：2011-10-07
申请人： Ali Bani-Hashemi
发明人： Ali Bani-Hashemi
IPC分类号： A61B5/055 , A61N5/10
CPC分类号： A61N5/1039 , A61B5/055 , A61N2005/105 , A61N2005/1054 , A61N2005/1091 , A61N2005/1094
摘要： A system includes acquisition of a first three-dimensional image of a patient volume using a magnetic resonance imaging scanner, acquisition of a second three-dimensional image of the patient volume using cone beam radiation emitted by the linear accelerator, and generation of a radiation treatment plan based on the first image and the second image.

3. 发明授权

US08923476B2 Acquisition of projection images for tomosynthesis 有权
标题翻译：获取用于层析合成的投影图像
公开(公告)号：US08923476B2
公开(公告)日：2014-12-30
申请号：US13369217
申请日：2012-02-08
申请人： Ajay Paidi , Jonathan Maltz , Ali Bani-Hashemi
发明人： Ajay Paidi , Jonathan Maltz , Ali Bani-Hashemi
IPC分类号： A61B6/00 , G06T11/00
CPC分类号： G06T11/006 , G06T2211/408 , G06T2211/436
摘要： Some aspects include acquisition of a first plurality of projection images of a volume using a megavoltage x-ray source, each of the first plurality of projection images associated with a respective one of a first plurality of locations of the megavoltage x-ray source, acquisition of a second plurality of projection images of the volume using a kilovoltage x-ray source, each of the second plurality of projection images associated with a respective one of a second plurality of locations of the kilovoltage x-ray source, and performance of digital tomosynthesis reconstruction to generate a three-dimensional image of the volume based on the first plurality of projection images and the second plurality of projection images. The first axis may be perpendicular to the second axis.
摘要翻译：一些方面包括使用兆伏级X射线源获取体积的第一多个投影图像，第一多个投影图像中的每一个与兆伏级x射线源的第一多个位置中的相应一个相关联，获取使用千伏X射线源的体积的第二多个投影图像中的每一个与所述千伏X射线源的第二多个位置中的相应一个相关联的第二多个投影图像以及数字断层合成的执行重构以基于第一多个投影图像和第二多个投影图像生成体积的三维图像。第一轴线可以垂直于第二轴线。

4. 发明授权

US08861672B2 Patient positioning system 有权
标题翻译：患者定位系统
公开(公告)号：US08861672B2
公开(公告)日：2014-10-14
申请号：US13298189
申请日：2011-11-16
申请人： Jonathan S. Maltz , Supratik Bose , Ali Bani-Hashemi , Ajay Paidi
发明人： Jonathan S. Maltz , Supratik Bose , Ali Bani-Hashemi , Ajay Paidi
IPC分类号： A61B6/03 , A61B6/00 , A61N5/10
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/488 , A61B6/5223 , A61N2005/105 , A61N2005/1061
摘要： A system includes acquisition of a three-dimensional computed tomography image of a patient volume at a computed tomography scanner, acquisition of projection images of the patient volume located at an isocenter of a linear accelerator, and determination of a transformation between a coordinate system of the linear accelerator and a coordinate system of the three-dimensional computed tomography image based on the projection images.
摘要翻译：一种系统包括在计算机断层摄影扫描仪中获取患者体积的三维计算机断层摄影图像，获取位于线性加速器的等角点处的患者体积的投影图像，以及确定坐标系的坐标系线性加速器和基于投影图像的三维计算机断层摄影图像的坐标系。

5. 发明授权

US08582719B2 System and method for tomosynthesis 有权
标题翻译：断层合成系统和方法
公开(公告)号：US08582719B2
公开(公告)日：2013-11-12
申请号：US13081441
申请日：2011-04-06
申请人： Ali Bani-Hashemi , Jonathan Maltz
发明人： Ali Bani-Hashemi , Jonathan Maltz
IPC分类号： A61B6/02 , A61B6/00
CPC分类号： A61B6/025 , A61B6/027 , A61B6/4007 , A61B6/54 , A61N2005/1061
摘要： A system and method for tomosynthesis, the method including emitting a respective imaging x-ray from each of a plurality of imaging x-ray sources disposed in a fixed relation with respect to one another, acquiring x-ray absorption projections of an object, each of the x-ray absorption projections associated with an imaging x-ray emitted by a respective one of the plurality of imaging x-ray sources, and performing digital tomosynthesis using the x-ray absorption projections to generate a cross-sectional image of the object.
摘要翻译：一种用于层析合成的系统和方法，所述方法包括从以相对于彼此固定关系设置的多个成像x射线源中的每一个发射相应的成像x射线，获取物体的x射线吸收投影，每个与由所述多个成像x射线源中的相应一个发射的成像x射线相关联的X射线吸收投影，以及使用所述x射线吸收投影进行数字断层合成以产生所述物体的横截面图像。

6. 发明申请

US20130090547A1 Combined Imaging Modalities for Radiation Treatment Planning 有权
标题翻译：辐射治疗计划的组合成像模式
公开(公告)号：US20130090547A1
公开(公告)日：2013-04-11
申请号：US13269324
申请日：2011-10-07
申请人： Ali Bani-Hashemi
发明人： Ali Bani-Hashemi
IPC分类号： A61B5/055
CPC分类号： A61N5/1039 , A61B5/055 , A61N2005/105 , A61N2005/1054 , A61N2005/1091 , A61N2005/1094
摘要： A system includes acquisition of a first three-dimensional image of a patient volume using a magnetic resonance imaging scanner, acquisition of a second three-dimensional image of the patient volume using cone beam radiation emitted by the linear accelerator, and generation of a radiation treatment plan based on the first image and the second image.
摘要翻译：一种系统包括使用磁共振成像扫描器获取患者体积的第一立体图像，使用由线性加速器发射的锥形束辐射获取患者体积的第二三维图像，以及产生放射治疗基于第一图像和第二图像计划。

7. 发明申请

US20060250586A1 Virtual digital shape projector 有权
标题翻译：虚拟数字投影机
公开(公告)号：US20060250586A1
公开(公告)日：2006-11-09
申请号：US11123747
申请日：2005-05-04
申请人： Ali Bani-Hashemi
发明人： Ali Bani-Hashemi
IPC分类号： G03B21/00
CPC分类号： G03B21/00 , A61N2005/1056 , G03B15/02
摘要： A projection system for projecting a shape onto a scene (e.g., the surface of an object, the body of a patient, or the like) so that the shape appears to be projected via a light beam emanating from a desired source location includes two or more projection assemblies for projecting planes of light which intersect the scene to form light stripes on the scene. The intersection of the light stripes defines a point of light projected onto the scene so that the point of light appears to emanate from the source location. The first and second projection assemblies rotate about first and second axes which extend through the source location for controlling the position of the point of light on the scene.
摘要翻译：用于将形状投影到场景（例如，物体的表面，患者身体等上）的投影系统，使得形状看起来通过从期望的源位置发出的光束投影包括两个或更多的投影组件用于投射与场景相交的光的平面，以在场景上形成光条纹。光条纹的交点定义投影到场景上的光点，使得光点看起来从源位置发出。第一和第二突出组件围绕延伸穿过源位置的第一和第二轴线旋转，以控制场景上的光点的位置。

8. 发明授权

US06351513B1 Fluoroscopy based 3-D neural navigation based on co-registration of other modalities with 3-D angiography reconstruction data 有权
标题翻译：基于3-D血管造影重建数据的其他方式的共同对照的基于荧光透视的3-D神经导航
公开(公告)号：US06351513B1
公开(公告)日：2002-02-26
申请号：US09607902
申请日：2000-06-30
申请人： Ali Bani-Hashemi , Arun Krishnan , James Williams
发明人： Ali Bani-Hashemi , Arun Krishnan , James Williams
IPC分类号： A61B603
CPC分类号： A61B6/481 , A61B5/055 , A61B6/12 , A61B6/504 , A61B6/5235 , A61B6/5247 , A61B2562/17 , Y10S378/901
摘要： A method and apparatus for providing a high-quality representation of a volume having a real-time 3-D reconstruction therein of movement of an object, wherein the real-time movement of the object is determined using a lower-quality representation of only a portion of the volume. The merger of 3-D angiography image representations acquired with other modalities, such as MR or CT, is disclosed. MR or CT modality images are registered with the 3-D Angiography data, such that those other images are brought into the same coordinate frame as the 3-D Angiography images. Movement of the object is detected in a 2-D X-ray fluoroscopy image and is reconstructed in a 3-D mode.
摘要翻译：一种用于提供其中具有物体的移动的实时3维重建的体积的高质量表示的方法和装置，其中使用较低质量的仅仅一个部分音量。公开了与其他方式（例如MR或CT）获得的3-D血管造影图像表示的合并。 MR或CT模态图像与3-D血管造影数据一起登记，使得其他图像被带入与3D血管造影图像相同的坐标系。在2维X射线荧光透视图像中检测物体的移动，并以3-D模式重建。

9. 发明申请

US20110006224A1 Digital Tomosynthesis in Ion Beam Therapy Systems 审中-公开
标题翻译：离子束治疗系统中的数字化合成
公开(公告)号：US20110006224A1
公开(公告)日：2011-01-13
申请号：US12500521
申请日：2009-07-09
申请人： Jonathan S. Maltz , Ali Bani-Hashemi
发明人： Jonathan S. Maltz , Ali Bani-Hashemi
IPC分类号： A61N5/00
CPC分类号： A61N5/103 , A61B6/025 , A61B6/4092 , A61B6/4233 , A61B6/466 , A61B6/583 , A61N2005/1052 , A61N2005/1061 , A61N2005/1087
摘要： Some embodiments include creation of projection images of a patient volume using one or more x-ray sources, performance of digital tomosynthesis on the projection images to generate a cross-sectional image of the patient volume, determination of a location of a target within the patient volume based on the cross-sectional image, determination of a location of a Bragg peak associated with an ion beam, and determination of a difference between the location of the target and the location of the Bragg peak.In some aspects, the patient volume is moved to move the target toward the location of the Bragg peak based on the difference. Additionally or alternatively, one or more characteristics of the ion beam may be changed to move the location of the Bragg peak toward the location of the target based on the difference. The one or more radiation sources may comprise a plurality of x-ray sources disposed in a fixed relationship to each other. Each of the plurality of x-ray sources may also be disposed in a fixed relationship to the ion beam source.
摘要翻译：一些实施例包括使用一个或多个x射线源创建患者体积的投影图像，在投影图像上执行数字断层合成以产生患者体积的横截面图像，确定患者在患者体内的位置的位置基于横截面图像的体积，确定与离子束相关联的布拉格峰的位置以及确定目标的位置与布拉格峰的位置之间的差异。在一些方面，移动患者体积以根据差异将目标移向布拉格峰的位置。附加地或替代地，可以改变离子束的一个或多个特性，以便基于该差异将布拉格峰的位置移动到目标的位置。一个或多个辐射源可以包括以彼此固定的关系设置的多个x射线源。多个x射线源中的每一个也可以以与离子束源固定的关系来设置。

10. 发明申请

US20100067647A1 DOSE-SPARING TOMOGRAPHIC IMAGING 有权
公开(公告)号：US20100067647A1
公开(公告)日：2010-03-18
申请号：US12210983
申请日：2008-09-15
申请人： Ali Bani-Hashemi , Christopher Amies
发明人： Ali Bani-Hashemi , Christopher Amies
IPC分类号： A61B6/00
CPC分类号： A61B6/502
摘要： A system includes emission of a first plurality of radiation beams from respective ones of a first plurality of locations along a first arc, acquisition of a first plurality of projection images of a target based on the first plurality of radiation beams, emission of a second plurality of radiation beams from respective ones of a second plurality of locations along a second arc, acquisition of a second plurality of projection images of the target based on the second plurality of radiation beams, and generation of a three-dimensional image of the target based on the first plurality of projection images and the second plurality of projection images, wherein a density of the first plurality of locations along the first arc is less than the density of the second plurality of locations along the second arc.In some aspects, at least one of the first plurality of radiation beams exhibits a first divergence angle, and at least one of the second plurality of radiation beams exhibits a second divergence angle different from the first divergence angle.
摘要翻译：一种系统包括从沿着第一弧的第一多个位置的相应位置发射第一多个辐射束，基于第一多个辐射束获取目标的第一多个投影图像，发射第二多个的辐射束，沿着第二弧的来自第二多个位置的相应的辐射束，基于所述第二多个辐射束获取所述目标的第二多个投影图像，以及基于所述第二多个辐射束生成所述目标的三维图像第一多个投影图像和第二多个投影图像，其中沿着第一弧的第一多个位置的密度小于沿着第二弧的第二多个位置的密度。在一些方面，第一多个辐射束中的至少一个呈现第一发散角，并且第二多个辐射束中的至少一个辐射束呈现与第一发散角不同的第二发散角。

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