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1. 发明授权

US06596863B2 Medical composition containing nitroetheneamine Derivative or salt there of as active constituent 失效
标题翻译：含有硝基乙烯胺的药物组合物作为活性成分的衍生物或盐
公开(公告)号：US06596863B2
公开(公告)日：2003-07-22
申请号：US10133752
申请日：2002-04-29
申请人： Fuminori Kato , Keizo Miyata , Hirohiko Kimura , Kazuhiro Yamamoto , Hiroyuki Ikegami , Hiromi Takeo
发明人： Fuminori Kato , Keizo Miyata , Hirohiko Kimura , Kazuhiro Yamamoto , Hiroyuki Ikegami , Hiromi Takeo
IPC分类号： C07D21376
CPC分类号： C07D495/04 , A61K31/00 , A61K31/428 , C07C243/16 , C07C243/20 , C07C243/22 , C07C243/28 , C07C243/38 , C07C251/76 , C07C251/80 , C07C251/86 , C07C257/06 , C07C281/02 , C07C311/49 , C07C311/51 , C07C323/36 , C07C327/58 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07D213/40 , C07D213/53 , C07D213/74 , C07D213/77 , C07D215/38 , C07D231/38 , C07D231/56 , C07D233/52 , C07D239/42 , C07D239/52 , C07D239/94 , C07D241/44 , C07D251/46 , C07D263/58 , C07D277/82 , C07D295/125 , C07D295/30 , C07D307/40 , C07D307/52 , C07D307/88 , C07D317/58 , C07D317/66 , C07D319/18 , C07D333/20 , C07D333/22 , C07D401/12 , C07D405/12 , C07D471/04
摘要： Process for producing a nitroetheneamine derivative or its stereoisomer, its tautomer or a salt thereof comprising reacting a compound of the formula with a compound of the formula R6—CH2NO2 to obtain a compound of the formula and reacting the resulting compound with a compound of the formula
摘要翻译：制备硝基乙烯胺衍生物或其立体异构体，其互变异构体或其盐的方法包括使制备式R 6 -CH 2 NO 2的化合物的化合物与式R 6 -CH 2 NO 2化合物反应，得到下式化合物，并使所得化合物与式

2. 发明授权

US06451792B1 Medical composition containing nitroetheneamine derivative or salt thereof as active constituent 失效
标题翻译：含有硝基乙烯胺衍生物或其盐作为活性成分的医药组合物
公开(公告)号：US06451792B1
公开(公告)日：2002-09-17
申请号：US09805781
申请日：2001-03-20
申请人： Fuminori Kato , Keizo Miyata , Hirohiko Kimura , Kazuhiro Yamamoto , Hiroyuki Ikegami , Hiromi Takeo
发明人： Fuminori Kato , Keizo Miyata , Hirohiko Kimura , Kazuhiro Yamamoto , Hiroyuki Ikegami , Hiromi Takeo
IPC分类号： A61K31135
CPC分类号： C07D495/04 , A61K31/00 , A61K31/428 , C07C243/16 , C07C243/20 , C07C243/22 , C07C243/28 , C07C243/38 , C07C251/76 , C07C251/80 , C07C251/86 , C07C257/06 , C07C281/02 , C07C311/49 , C07C311/51 , C07C323/36 , C07C327/58 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07D213/40 , C07D213/53 , C07D213/74 , C07D213/77 , C07D215/38 , C07D231/38 , C07D231/56 , C07D233/52 , C07D239/42 , C07D239/52 , C07D239/94 , C07D241/44 , C07D251/46 , C07D263/58 , C07D277/82 , C07D295/125 , C07D295/30 , C07D307/40 , C07D307/52 , C07D307/88 , C07D317/58 , C07D317/66 , C07D319/18 , C07D333/20 , C07D333/22 , C07D401/12 , C07D405/12 , C07D471/04
摘要： A medical composition containing, as an active constituent, a nitroetheneamine derivative represented by the formula (I): wherein the substituents are as defined in the disclosure, its stereoisomers, its tautomers or a salt thereof.
摘要翻译：作为活性成分含有由式（I）表示的硝基乙烯胺衍生物的医药组合物，其中取代基如本公开内容所定义，其立体异构体，其互变异构体或其盐。

3. 发明申请

US20110225381A1 NONVOLATILE STORAGE DEVICE, ACCESS DEVICE AND NONVOLATILE STORAGE SYSTEM 有权
标题翻译：非易失性存储设备，访问设备和非易失性存储系统
公开(公告)号：US20110225381A1
公开(公告)日：2011-09-15
申请号：US13046053
申请日：2011-03-11
申请人： Masato Suto , Toshiyuki Honda , Keizo Miyata
发明人： Masato Suto , Toshiyuki Honda , Keizo Miyata
IPC分类号： G06F12/00 , G06F12/02 , G06F12/16
CPC分类号： G11C11/5628 , G06F3/0619 , G06F3/0652 , G06F3/0679 , G06F11/1446 , G06F12/0246 , G06F2212/7205 , Y02D10/13
摘要： A memory controller includes a reading/writing control unit for controlling writing and reading of data to and from a physical block of a nonvolatile memory, a writing mode table for storing one of a first writing mode of protecting data against a power shutdown during writing and a second writing mode of writing data at a higher speed than the first writing mode, and a setting unit for setting the writing mode received from an access device in a writing mode table. The reading/writing control unit performs data writing based on the writing mode that has been set in the writing mode table.
摘要翻译：存储器控制器包括用于控制从非易失性存储器的物理块写入数据和从非易失性存储器的物理块读取数据的读/写控制单元，用于存储写入期间保护数据的第一写入模式与电源关闭的第一写入模式的写模式表;以及以比第一写入模式更高的速度写入数据的第二写入模式，以及设置单元，用于在写入模式表中设置从访问设备接收的写入模式。读取/写入控制单元基于在写入模式表中设置的写入模式执行数据写入。

4. 发明授权

US06982848B2 Disk apparatus and head positioning method 失效
标题翻译：磁盘设备和磁头定位方法
公开(公告)号：US06982848B2
公开(公告)日：2006-01-03
申请号：US10852135
申请日：2004-05-25
申请人： Toshio Inaji , Keizo Miyata , Hiroshi Kohso , Makoto Umeda
发明人： Toshio Inaji , Keizo Miyata , Hiroshi Kohso , Makoto Umeda
IPC分类号： G11B5/596 , G11B21/02
CPC分类号： G11B5/596 , G11B5/5582 , G11B21/106
摘要： A disk apparatus includes: an actuator 7; a driver 10; a voltage detector 11 for outputting first voltage signal Ed which is produced in a driving coil 5 of the actuator 7; a voltage signal adjuster 16 for outputting pseudo disturbance signal ur and generating second voltage signal Ed+ from pseudo disturbance signal ur, driving signal u, first voltage signal Ed, and disturbance estimation signal τdest; a disturbance estimator 12 for estimating the magnitude of disturbance load τd applied to a magnetic head 2 from driving signal u and second voltage signal Ed+ to output disturbance estimation signal τdest; a position detector 13 for generating position error signal e which corresponds to a current position of the magnetic head 2; a position controller 14 for generating control signal c from position error signal e; and a corrector 15 for generating driving signal u from disturbance estimation signal τdest and position control signal c.
摘要翻译：盘装置包括：致动器7; 司机10; 用于输出在致动器7的驱动线圈5中产生的第一电压信号Ed的电压检测器11; 用于从伪干扰信号ur输出伪干扰信号ur并产生第二电压信号Ed + SUP的电压信号调节器16，驱动信号u，第一电压信号Ed和干扰估计信号taud < / SUB>; 用于估计从驱动信号u和第二电压信号Ed + SUP施加到磁头2的干扰负载taud的大小的干扰估计器12，以输出干扰估计信号taud < 用于产生对应于磁头2的当前位置的位置误差信号e的位置检测器13; 位置控制器14，用于从位置误差信号e产生控制信号c; 以及用于从干扰估计信号taud和/或位置控制信号c产生驱动信号u的校正器15。

5. 发明授权

US06714367B1 Master information medium and method of master information recording 失效
标题翻译：主信息介质和主信息记录方法
公开(公告)号：US06714367B1
公开(公告)日：2004-03-30
申请号：US09555583
申请日：2000-08-07
申请人： Tatsuaki Ishida , Hiroshi Ryonai , Nobuyuki Komura , Keizo Miyata , Kiyokazu Tohma
发明人： Tatsuaki Ishida , Hiroshi Ryonai , Nobuyuki Komura , Keizo Miyata , Kiyokazu Tohma
IPC分类号： G11B586
CPC分类号： B82Y10/00 , G11B5/64 , G11B5/656 , G11B5/74 , G11B5/743 , G11B5/82 , G11B5/855 , G11B5/865
摘要： A master information carrier has a shape pattern corresponding to an information signal array to be recorded on a magnetic recording medium, and the shape pattern is provided by arraying a ferromagnetic thin film deposited on a nonmagnetic substrate surface. The ferromagnetic thin film is either a soft magnetic film or semihard magnetic film having not more than 40 kA/m coercive force in track length direction of the information signals, and residual magnetization of the ferromagnetic thin film in the track length direction of the information signals is greater than coercive force of the magnetic recording medium. As a result, a master information carrier with superior magnetic recording performance can be obtained.
摘要翻译：主信息载体具有对应于要记录在磁记录介质上的信息信号阵列的形状图案，并且通过排列沉积在非磁性基板表面上的铁磁性薄膜来提供形状图案。铁磁性薄膜是在信息信号的轨道长度方向上具有不超过40kA / m矫顽力的软磁性膜或半硬磁性薄膜，以及信息信号的磁道长度方向上的铁磁性薄膜的剩余磁化大于磁记录介质的矫顽力。结果，可以获得具有优良磁记录性能的主信息载体。

6. 发明授权

US06646820B1 Method for recording magnetic recording medium 失效
标题翻译：记录磁记录介质的方法
公开(公告)号：US06646820B1
公开(公告)日：2003-11-11
申请号：US09869947
申请日：2001-07-03
申请人： Tatsuaki Ishida , Taizou Hamada , Hideyuki Hashi , Keizo Miyata , Yasuaki Ban , Hiromi Kita
发明人： Tatsuaki Ishida , Taizou Hamada , Hideyuki Hashi , Keizo Miyata , Yasuaki Ban , Hiromi Kita
IPC分类号： G11B586
CPC分类号： G11B5/865 , G11B5/127 , G11B5/23 , G11B5/82
摘要： A master information carrier (2) with an arranged pattern formed of a ferromagnetic film in a shape corresponding to information signals is superposed on a magnetic recording medium (1) and the arranged pattern formed of a ferromagnetic film is magnetized with a magnetizing head (6), thus transfer-recording the arranged pattern into the magnetic recording medium as a magnetized pattern. The magnetizing head includes an annular magnetic circuit with a gap, and a strength of a magnetic field applied to the master information carrier by magnetic flux leaking from portions other than the gap is set to be 20% or less of that of a magnetic field applied to the master information carrier by magnetic flux leaking from the gap. Quality deterioration due to various conditions during recording can be prevented and uniform recording with less variation depending on position on the magnetic recording medium is achieved.
摘要翻译：具有与信息信号相对应的铁磁膜形成的排列图案的主信息载体（2）叠加在磁记录介质（1）上，由铁磁膜形成的排列图案被磁化头（6 ），从而将布置的图案作为磁化图案转印记录到磁记录介质中。磁化头包括具有间隙的环形磁路，并且通过从除了间隙之外的部分泄漏的磁通量施加到主信息载体的磁场强度设定为施加的磁场的磁场强度的20％以下通过磁通从主信息载体泄漏出来。可以防止由记录期间的各种条件导致的质量劣化，并且实现根据磁记录介质上的位置具有较小变化的均匀记录。

7. 发明授权

US5247070A N-terminal muteins of tumor necrosis factor 失效
标题翻译：肿瘤坏死因子的N-末端MUTEIN
公开(公告)号：US5247070A
公开(公告)日：1993-09-21
申请号：US763512
申请日：1991-09-20
申请人： Nobutoshi Yamada , Masanari Kato , Keizo Miyata , Yoshiyuki Aoyama , Hiroshi Shikama
发明人： Nobutoshi Yamada , Masanari Kato , Keizo Miyata , Yoshiyuki Aoyama , Hiroshi Shikama
IPC分类号： A61K38/00 , A61P35/00 , C07K14/00 , C07K14/52 , C07K14/525 , C07K14/78 , C07K19/00 , C12N1/21 , C12N15/28 , C12P21/02 , C12R1/19
CPC分类号： C07K14/525 , C07K14/78 , A61K38/00 , C07K2319/00 , Y10S930/144
摘要： A polypeptide which is a tumor necrosis factor polypeptide having an amino acid sequence represented by from the 1st Ser to the 155th Leu as shown by SEQ ID NO:1 in the Sequence Listing, or its mutein, wherein the amino acid sequence of the 1st Ser to the 8th Asp of the SEQ ID NO:1 or the corresponding amino acid sequence of the mutein is replaced by an amino acid sequence containing at least one amino acid sequence of cell-adherent peptide of laminin and from 5 to 30 amino acids. Also disclosed are a recombinant plasmid containing a DNA encoding such a polypeptide, a recombinant microbial cell transformed by such a recombinant plasmid, a process for producing the polypeptide, a pharmaceutical composition comprising the polypeptide as an active ingredient, and a DNA for the polypeptide.

8. 发明授权

US07019938B2 Head positioning method, and disk apparatus using the same 失效
标题翻译：头定位方法和使用其的磁盘装置
公开(公告)号：US07019938B2
公开(公告)日：2006-03-28
申请号：US10692652
申请日：2003-10-27
申请人： Keizo Miyata , Toshio Inaji , Hiroshi Kohso
发明人： Keizo Miyata , Toshio Inaji , Hiroshi Kohso
IPC分类号： G11B5/596
CPC分类号： G11B5/5552 , G11B21/083
摘要： A first estimator 13 estimates the position of a head based on a VCM driving signal u1 and a voltage signal Va output from a VCM 6 to output a first head position estimation signal x1est. The first estimator 13 estimates the disturbance acting on a head supporting mechanism 8 to output a disturbance estimation signal τdest. A second estimator 15 estimates the displacement of the head based on a control signal c2 for a fine adjustment actuator 7 to output a displacement estimation signal x2est. The first head position estimation signal x1est and the displacement estimation signal x2est are added together to obtain a second head position estimation signal xest. A position error signal e is generated using a head position signal x obtained by detecting the servo information and the second head position estimation signal xest. A disturbance compensator 10 synthesizes a VCM control signal c1 with the disturbance estimation signal τdest to generate the VCM driving signal u1.
摘要翻译：第一估计器13基于VCM驱动信号u 1 1和从VCM 6输出的电压信号Va来估计头的位置，以输出第一头位置估计信号x＆lt; 1＆ SUB>。第一估计器13估计作用在头支撑机构8上的扰动，以输出干扰估计信号τ> dest dest dest。第二估计器15基于用于精调节致动器7的控制信号c 2估计头的位移，以输出位移估计信号x2stest 。将第一头部位置估计信号x 1＆lt; 1＆gt;和位移估计信号x＆lt; 2est＆gt;相加在一起以获得第二头部位置估计信号x 。使用通过检测伺服信息和第二打印头位置估计信号x获得的打印头位置信号x来产生位置误差信号e。干扰补偿器10将VCM控制信号c 1与干扰估计信号τSUB分配，以产生VCM驱动信号u 1。

9. 发明授权

US06980380B2 Master information carrier and method for manufacturing magnetic disk 失效
标题翻译：主信息载体和制造磁盘的方法
公开(公告)号：US06980380B2
公开(公告)日：2005-12-27
申请号：US10330172
申请日：2002-12-27
申请人： Keizo Miyata , Hideyuki Hashi , Tatsuaki Ishida
发明人： Keizo Miyata , Hideyuki Hashi , Tatsuaki Ishida
IPC分类号： G11B5/82 , G11B5/86 , G11B23/50
CPC分类号： B82Y10/00 , G11B5/743 , G11B5/82 , G11B5/865 , G11B23/505
摘要： A master information carrier includes a high-level region and a low-level region that are formed on a non-magnetic base. The high-level region includes a ferromagnetic thin film pattern that corresponds to preformat information signals. The master information carrier is brought into close contact with a magnetic disk by exhausting a gas from a hole of the magnetic disk to generate negative pressure in a space between the low-level region and the magnetic disk. In this case, to prevent deformation of the central portion of the master information carrier, an inner edge of the high-level region in the radial direction is extended to the vicinity of a hole edge of the magnetic disk so that a portion of the high-level region comes into contact with the vicinity of the hole edge. This configuration can improve the close contact between the master information carrier and the magnetic disk, thus achieving higher reliability of magnetic transfer recording.
摘要翻译：主信息载体包括形成在非磁性基底上的高电平区域和低电平区域。高电平区域包括对应于预格式化信息信号的铁磁薄膜图案。通过从磁盘的孔排出气体而使主信息载体与磁盘紧密接触，以在低电平区域和磁盘之间的空间中产生负压。在这种情况下，为了防止主信息载体的中心部分的变形，高度区域的径向内侧的边缘延伸到磁盘的孔边缘附近，使得一部分高水平区域与孔边缘附近接触。这种配置可以改善主信息载体和磁盘之间的紧密接触，从而实现更高的磁转移记录的可靠性。

10. 发明授权

US06903896B2 Head positioning method, and disk apparatus using the same 失效
标题翻译：头定位方法和使用其的磁盘装置
公开(公告)号：US06903896B2
公开(公告)日：2005-06-07
申请号：US10606124
申请日：2003-06-26
申请人： Keizo Miyata , Toshio Inaji
发明人： Keizo Miyata , Toshio Inaji
IPC分类号： G11B5/55 , G11B5/596
CPC分类号： G11B5/5526
摘要： A disturbance compensation signal is produced by estimating the magnitude of disturbance acting upon an actuator based on a driving signal and a voltage signal generated when driving the actuator. A control signal is produced by multiplying the disturbance compensation signal by a gain adjustment coefficient. A head position error signal is produced based on the target position of a magnetic head and the current position of the magnetic head that is detected based on servo information recorded in advance on a magnetic disk. A gain adjuster obtains the driving signal by adding together the control signal and a position control signal. The actuator is driven with the driving signal output from the gain adjuster.
摘要翻译：通过基于驱动信号和驱动致动器时产生的电压信号来估计作用于致动器的干扰的大小来产生扰动补偿信号。通过将扰动补偿信号乘以增益调整系数来产生控制信号。基于磁头的目标位置和基于预先记录在磁盘上的伺服信息检测的磁头的当前位置来产生磁头位置误差信号。增益调节器通过将控制信号和位置控制信号相加在一起来获得驱动信号。致动器由增益调节器输出的驱动信号驱动。

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