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1. 发明申请

US20050109951A1 Novel device, system and method for fluorescence detection 审中-公开
标题翻译：用于荧光检测的新型装置，系统和方法
公开(公告)号：US20050109951A1
公开(公告)日：2005-05-26
申请号：US10500186
申请日：2002-12-26
申请人： Falk Fish , Zvi Greenberg , Ouriel Faktor
发明人： Falk Fish , Zvi Greenberg , Ouriel Faktor
IPC分类号： G01N21/64 , G01N21/75 , G01N21/77 , G01N21/86
CPC分类号： G01N21/645 , G01N21/64 , G01N21/8483 , G01N33/549 , G01N2021/6439 , G01N2021/757 , G01N2021/7759 , G01N2021/7763 , G01N2021/7786 , G01N2201/0221 , G01N2201/0222 , G01N2201/0245 , G01N2201/062 , G01N2201/0628
摘要： A device, system and method for portable fluorescence detection. The portable device of the present invention features a low power light, in which a wavelength range is defined as at least one wavelength of light. The light source is preferably highly energy efficient, such that a majority of the electrical power which is consumed is then converted into transmitted light. The emitted light from the excited fluorophore is then preferably detected with any low cost and low power photodetector. Although optionally a highly sensitive optical detector may be used, preferably fluorescence is detected with any light sensing device, such as a regular photodiode or a CCD (charge-coupled device) sensor for example.
摘要翻译：用于便携式荧光检测的装置，系统和方法。本发明的便携式装置具有低功率光，其中波长范围被定义为至少一个波长的光。光源优选地是高能量的，使得消耗的大部分电功率然后被转换成透射光。然后优选用任何低成本和低功率光电检测器检测来自激发的荧光团的发射光。尽管可选地使用高灵敏度的光学检测器，但是优选地，例如使用诸如常规光电二极管或CCD（电荷耦合器件）传感器的任何光感测装置来检测荧光。

2. 发明申请

US20060110283A1 Photometric determination of coagulation time in undiluted whole blood 审中-公开
标题翻译：未稀释全血中凝血时间的光度测定
公开(公告)号：US20060110283A1
公开(公告)日：2006-05-25
申请号：US10516053
申请日：2003-11-12
申请人： Falk Fish
发明人： Falk Fish
IPC分类号： G01N21/64
CPC分类号： G01N21/272 , G01N21/03 , G01N21/82 , G01N21/8483 , G01N33/4905 , G01N33/86 , G01N2021/0321 , G01N2021/0328 , G01N2021/0346 , G01N2021/825 , G01N2201/0221 , G01N2201/0624
摘要： A device, system and method for photometric detection of coagulation in whole blood. The present invention is easy to implement and operate. Furthermore, the present invention has the advantage of being considered to fulfill the desired standard of using photometry for measuring blood coagulation. Also, a photometric coagulation test device for whole blood specimens according to the present invention provides medical accuracy to the home user and, at the same time, is simple to construct. The present invention is also useful for detecting and determining blood agglutination, for example as the results of a serological reaction with an antibody.
摘要翻译：全血凝结光度检测装置，系统及方法。本发明易于实现和操作。此外，本发明的优点在于被认为满足使用光度法测量血液凝固的期望标准。此外，根据本发明的用于全血样本的光度凝固测试装置向家庭用户提供医学准确性，并且同时构造简单。本发明也可用于检测和测定血液凝集，例如作为与抗体血清学反应的结果。

3. 发明授权

US07591978B2 Solid phase test device for sialidase assay 有权
标题翻译：唾液酸酶测定固相试验装置
公开(公告)号：US07591978B2
公开(公告)日：2009-09-22
申请号：US11502192
申请日：2006-08-10
申请人： Oren Shraga Dwir , Tomer Keren , Falk Fish
发明人： Oren Shraga Dwir , Tomer Keren , Falk Fish
IPC分类号： G01N21/00
CPC分类号： C12Q1/34 , C12Q2334/50 , C12Q2334/52 , G01N2333/195 , G01N2333/30 , G01N2333/36 , G01N2800/36
摘要： A solid-phase test device and a method for the detection of sialidase activity in a fluid sample. The test device includes a solid support provided with a pre-deposited dry form of a sialidase detecting composition. The sialidase detecting composition includes a sialidase substrate and a color-developing reagent. When the sialidase substrate is exposed to sialidase it yields an intermediate compound which reacts with the color-developing reagent to form a detectable color change.
摘要翻译：固相试验装置和用于检测流体样品中唾液酸酶活性的方法。测试装置包括具有预沉积干燥形式的唾液酸酶检测组合物的固体支持物。唾液酸酶检测组合物包括唾液酸酶底物和显色剂。当唾液酸酶底物暴露于唾液酸酶时，产生与显色剂反应形成可检测颜色变化的中间体化合物。

4. 外观设计

USD293374S Assay cards 失效
公开(公告)号：USD293374S
公开(公告)日：1987-12-22
申请号：US672928
申请日：1984-11-19
申请人： Max Herzberg , Falk Fish
设计人： Max Herzberg , Falk Fish

5. 发明申请

US20080241953A1 Method and Apparatus for Patterning a Bibulous Substrate 审中-公开
标题翻译：用于图案化吸收性基材的方法和装置
公开(公告)号：US20080241953A1
公开(公告)日：2008-10-02
申请号：US12065780
申请日：2006-09-06
申请人： Falk Fish
发明人： Falk Fish
IPC分类号： G01N21/78 , B01J19/00 , B41F1/00
CPC分类号： B01L3/5023 , B01L2200/10 , B01L2200/12 , B01L2300/0636 , B01L2300/0681 , B01L2300/0825 , B01L2300/126 , B01L2300/165 , D21H25/005
摘要： A method of patterning a bibulous substrate is disclosed. The method comprises contacting the bibulous substrate with a first surface being coated by a barrier compound, using a second surface having a predetermined pattern engraved thereon, and applying heat and pressure onto the first surface such as to pattern the bibulous substrate in a predetermined pattern.
摘要翻译：公开了一种图案化吸水性衬底的方法。该方法包括使吸水性衬底与被阻挡化合物涂覆的第一表面接触，使用刻在其上的预定图案的第二表面，并将热和压力施加到第一表面上，以便以预定图案对吸水衬底进行图案化。

6. 发明授权

US07060453B1 Method and kit for the determination of analyte concentration in blood 有权
标题翻译：用于测定血液中分析物浓度的方法和试剂盒
公开(公告)号：US07060453B1
公开(公告)日：2006-06-13
申请号：US09763415
申请日：1999-08-19
申请人： Falk Fish
发明人： Falk Fish
IPC分类号： C12Q1/54 , C12Q1/00 , A01N1/02 , A61K39/00 , A61K45/00
CPC分类号： G01N33/66 , G01N33/50 , G01N33/721 , Y10T436/25375
摘要： A method is provided for determining the level of an analyte in the blood of an individual based on determination of the level of the same analyte in non-blood sample (e.g. urine, saliva and hair) obtained from the individual. The non-blood sample contains red blood cells and the volume of the blood in the sample together with the amount of the analyte in the sample are the basis for calculating the level of the analyte in the individual's blood. Kits for carrying out the above method are also provided.
摘要翻译：提供了一种用于基于从个体获得的非血液样品（例如尿液，唾液和头发）中相同分析物的水平的测定来确定个体血液中分析物的水平的方法。非血液样品含有红细胞，样品中的血液体积和样品中的分析物的量是计算个体血液中分析物水平的基础。还提供了用于执行上述方法的套件。

7. 发明申请

US20060105402A1 Blood type method system and device 审中-公开
标题翻译：血型法系统及装置
公开(公告)号：US20060105402A1
公开(公告)日：2006-05-18
申请号：US11272971
申请日：2005-11-15
申请人： Gennady Rott , Fred Samuels , Falk Fish , Ariela Ben-Zvi
发明人： Gennady Rott , Fred Samuels , Falk Fish , Ariela Ben-Zvi
IPC分类号： G01N33/567 , C12Q1/56 , C12M1/34
CPC分类号： G01N33/543 , G01N33/5302 , G01N33/54313 , G01N33/80
摘要： A method for the detection and/or visualization of particle agglutination in a particle suspension is provided, comprising placing a volume of the particle suspension and a volume of a solution or suspension containing an agglutinating agent at substantially the same selected location on a surface of a filter constructed so as to permit passage of individual unagglutinated particles in a direction perpendicular to the surface. A wash solution at optionally placed at substantially the same location as that of said agglutinating agent, and the surface is observed for the presence of particles. There is also provided a method for detection of agglutination reactions, such as used in blood grouping, reverse grouping and cross-matching. A device and a kit based on the invention is also claimed, which facilitates blood grouping, reverse grouping and matching in non-laboratory environment without the need for laboratory instruments.
摘要翻译：提供了用于检测和/或可视化颗粒悬浮液中的颗粒凝集的方法，包括将体积的颗粒悬浮液和一定体积的含有凝集剂的溶液或悬浮液放置在基本上相同的选定位置的过滤器被构造成允许单个未凝集的颗粒在垂直于表面的方向上通过。任选地在与所述凝集剂的位置基本上相同的位置处的洗涤溶液，并观察表面存在颗粒。还提供了用于血液分组，反向分组和交叉匹配中使用的凝集反应检测方法。还要求保护基于本发明的装置和试剂盒，其不需要实验室仪器便于非实验室环境中的血液分组，反向分组和匹配。

8. 发明申请

US20230015833A1 Apparatus and method for personalized hormonal diagnostics and therapy 有权
公开(公告)号：US20230015833A1
公开(公告)日：2023-01-19
申请号：US17857096
申请日：2022-07-04
申请人： Natalia Shtraizent , Henry Grage , Falk Fish
发明人： Natalia Shtraizent , Henry Grage , Falk Fish
IPC分类号： G01N33/76 , G01N33/74 , G16H70/60 , G16H10/60
摘要： A method and system for measuring hormone levels in human samples. Either actual levels can be measured, or hormone related parameters can be measured with computation extrapolating the parameters to the actual hormone level. A patient hormone level can be compared against a population database based on age, gender and other factors to determine a score for a particular hormone. A dosage of the hormone being given a patient can be automatically adjusted based on the score with optional approval of the adjustment made by a health professional. This is particularly useful in hormone replacement therapy and in-vitro fertilization.

9. 发明申请

US20100173423A1 Multiple testing apparatus and method 审中-公开
标题翻译：多种检测仪器及方法
公开(公告)号：US20100173423A1
公开(公告)日：2010-07-08
申请号：US12319306
申请日：2009-01-06
申请人： Vivian Zuaretz , Falk Fish
发明人： Vivian Zuaretz , Falk Fish
IPC分类号： G01N33/48
CPC分类号： G01N33/54386 , G01N33/558
摘要： A multiple test strip assembly comprising a non-bibulous support, a sample application site comprising a defined area of said non-bibulous support delimited by a liquid impervious barrier, and at least two test strips placed on said support, each having a bibulous sample receiving pad, wherein the sample receiving pad of each of said at least two test strips is in contact with said sample application site.
摘要翻译：包括非吸水性支撑物的多个测试条组件，包括由液体不可渗透屏障限定的所述非吸水支撑物的限定区域的样品施加位置和放置在所述支撑件上的至少两个测试条，每个测试条具有吸收样品接收垫，其中所述至少两个测试条中的每一个的样品接收垫与所述样品施加部位接触。

10. 发明申请

US20080038766A1 Dry format sialidase assay 有权
标题翻译：干式唾液酸酶测定
公开(公告)号：US20080038766A1
公开(公告)日：2008-02-14
申请号：US11502192
申请日：2006-08-10
申请人： Oren Shraga Dwir , Tomer Keren , Falk Fish
发明人： Oren Shraga Dwir , Tomer Keren , Falk Fish
IPC分类号： C12Q1/34 , C12M3/00
CPC分类号： C12Q1/34 , C12Q2334/50 , C12Q2334/52 , G01N2333/195 , G01N2333/30 , G01N2333/36 , G01N2800/36
摘要： A solid-phase test device and method for the detection of sialidase activity in a fluid sample. The test device comprises a solid support provided with pre-deposited dry form of a sialidase detecting composition comprising a sialidase substrate and a color-developing reagent, wherein the sialidase substrate when exposed to sialidase yields an intermediate compound which reacts with the color-developing reagent to form a detectable color change.
摘要翻译：一种用于检测流体样品中唾液酸酶活性的固相试验装置和方法。测试装置包括提供有预沉积干燥形式的包含唾液酸酶底物和显色剂的唾液酸酶检测组合物的固体支持物，其中当唾液酸酶底物暴露于唾液酸酶时产生与显色剂反应的中间体化合物以形成可检测的颜色变化。

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