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    • 4. 发明授权
    • Device for the determination of blood clotting by capacitance or resistance
    • 用于通过电容或电阻测定血液凝固的装置
    • US07021122B1
    • 2006-04-04
    • US09646348
    • 1999-03-18
    • Yossef RosembergFalk FishRaphael Levi
    • Yossef RosembergFalk FishRaphael Levi
    • G01N11/00
    • G01N33/491G01N11/04G01N2011/0066
    • A sensor device (10) and a method for measuring a viscosity of a sample of a liquid. The sensor features a chamber (12) for receiving the sample of the liquid, two electrodes (18) disposed either on the surfaces of the chamber, but possibly isolated from contacting the sample, or electrodes located externally to the chamber, and a capacitance measuring circuit (25). The sensor is used by connecting to a measurer for determining a capacitance on the electrodes, such that the capacitance directly reflects a volume occupied by the sample of the liquid. Preferably, the liquid is blood and the capacitance is used to determine the clotting time of the blood. Also preferably, a cover for the chamber is provided with at least one aperture, which more preferably is a mesh. Alternatively, an electrical property such as the amplitude of current passed through the sample is used to determine clotting time. Also preferably, the time period required for the maximum capacitance to be reached could be measured. Alternatively, the capacitance could be measured after a fixed time period (34) had elapsed. Also alternatively, the time period required for the maximum current to be reached could be measured, or the amount of current could be measured after a fixed time period had elapsed. In preferred embodiments of the present invention, a kit for measuring the clotting time of blood is provided. In other preferred embodiments of the present invention, methods are provided for using the kit and device of the present invention.
    • 传感器装置(10)和用于测量液体样品的粘度的方法。 传感器具有用于接收液体样品的腔室(12),设置在腔室表面上但可能与接触样品或位于腔室外部的电极隔离的两个电极(18)和电容测量 电路(25)。 传感器通过连接到用于确定电极上的电容的测量器来使用,使得电容直接反映由液体样品占据的体积。 优选地,液体是血液,并且电容用于确定血液的凝血时间。 还优选地,用于腔室的盖设置有至少一个孔,更优选地是网。 或者,使用诸如通过样品的电流的振幅的电特性来确定凝固时间。 还优选地,可以测量达到最大电容所需的时间。 或者,可以在经过固定时间段(34)之后测量电容。 或者,可以测量达到最大电流所需的时间段,或者在固定时间段过去之后可以测量电流量。 在本发明的优选实施方案中,提供了用于测量血液凝血时间的试剂盒。 在本发明的其它优选实施方案中,提供了使用本发明的试剂盒和装置的方法。