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    • 1. 发明授权
    • Watercraft trailer
    • 船舶拖车
    • US08011683B2
    • 2011-09-06
    • US12261712
    • 2008-10-30
    • Hugo BrissonChristian LabbeDaniel MercierJoey LaroucheBruno GirouardEric Fournier
    • Hugo BrissonChristian LabbeDaniel MercierJoey LaroucheBruno GirouardEric Fournier
    • B63B21/54B60P3/10
    • B60P3/1033B60P3/1066
    • A watercraft trailer has a releasable connector for releasably connecting a watercraft to the trailer. The releasable connector has a lever pivotally connected to a connector support and a hook connected to the lever. Pivoting of the lever towards a front of the trailer moves the releasable connector to a locked position and pivots the hook towards the front of the trailer. A locking mechanism prevents the releasable connector from moving to an unlocked position by applying forces to any one of the lever and the hook that would otherwise pivot the lever and the hook towards a rear of the trailer. Unlocking the locking mechanism moves the releasable connector to the unlocked position and pivots the hook towards the rear of the trailer. A method of securing a watercraft to a watercraft trailer and a method of releasing a watercraft from a watercraft trailer are also disclosed.
    • 船舶拖车具有用于将船只与拖车可释放地连接的可释放连接器。 可释放连接器具有枢转地连接到连接器支撑件的杆和连接到杠杆的钩。 将杠杆转向拖车前部将可释放连接器移动到锁定位置,并将钩向拖车前方转动。 锁定机构通过向杠杆和钩中的任何一个施加力而防止可释放连接器移动到解锁位置,否则将使杆和钩朝向拖车的后部转动。 解锁锁定机构将可释放连接器移动到解锁位置,并将挂钩向拖车的后部转动。 还公开了将船只固定在船舶拖车上的方法以及从船只拖车释放船只的方法。
    • 3. 发明授权
    • Watercraft trailer having an intake protector
    • 船舶拖车具有进气保护器
    • US07891689B2
    • 2011-02-22
    • US12263037
    • 2008-10-31
    • Hugo BrissonChristian LabbeDaniel MercierJoey LaroucheBruno GirouardEric Fournier
    • Hugo BrissonChristian LabbeDaniel MercierJoey LaroucheBruno GirouardEric Fournier
    • B60P3/10
    • B60P3/1033B60P3/1066
    • A watercraft trailer has a watercraft receiving portion and a lower frame adapted to support a watercraft in the watercraft receiving portion. The lower frame has at least one a longitudinally extending member, a front portion, and a rear portion, a rearmost part of the rear portion being a rear end. The trailer also has a hitch coupler connected to the front portion of the lower frame, a first wheel, having a rotation axis, and a second wheel operatively connected to the lower frame. The trailer has a longitudinally extending intake protector connected to the rear portion of the lower frame. At least a portion of the intake protector is disposed between the rotation axis and the rear end of the lower frame, such that when the watercraft is received in the watercraft receiving portion, the intake protector is disposed below at least a portion of the watercraft.
    • 船舶拖车具有船舶接收部分和适于在船只接收部分中支撑船只的下部框架。 下框架具有至少一个纵向延伸的构件,前部和后部,后部的最后部分是后端。 拖车还具有连接到下框架的前部的挂钩联接器,具有旋转轴线的第一轮和可操作地连接到下框架的第二轮。 拖车具有连接到下框架的后部的纵向延伸的进气保护器。 进气保护器的至少一部分设置在下框架的旋转轴线和后端之间,使得当船只被接收在船只接收部分中时,进气保护器设置在船舶的至少一部分下方。
    • 6. 发明申请
    • Salts, Solvates and Pharmaceutical Compositions of Macrocyclic Ghrelin Receptor Agonists and Methods of Using the Same
    • 大环素Ghrelin受体激动剂的盐,溶剂化物和药物组合物及其使用方法
    • US20110245159A1
    • 2011-10-06
    • US12937040
    • 2010-09-29
    • Hamid R. HoveydaMartin VézinaEric FournierRené GagnonPatrick Bhérer
    • Hamid R. HoveydaMartin VézinaEric FournierRené GagnonPatrick Bhérer
    • A61K38/12C07K5/08C07K1/14C07K1/107C07K1/34A61P1/00A61P1/14A61P1/04A61P1/08A61P29/00A61P3/00A61P5/00A61P9/00A61P25/00A61P19/08A61P35/00
    • C07D273/00A61K9/0019
    • The present invention provides novel salts and solvates of macrocyclic compounds that bind to and/or are functional agonists of the ghrelin (growth hormone secretagogue) receptor. The invention also relates to polymorphs of these salts and solvates, pharmaceutical compositions containing these salts or solvates, and methods of using the pharmaceutical compositions. These pharmaceutical compositions are useful as therapeutics for a range of disease indications, in particular, for treatment and prevention of gastrointestinal disorders including, but not limited to, postoperative ileus, gastroparesis, including diabetic and postsurgical gastroparesis, opioid bowel dysfunction, chronic intestinal pseudo-obstruction, short bowel syndrome, functional gastrointestinal disorders and gastrointestinal dysmotility, such as that occurring in conjunction with other disease states, in critical care situations or as a result of treatment with pharmaceutical agents. Additionally, the pharmaceutical compositions have application to the treatment and prevention of metabolic and/or endocrine disorders, cardiovascular disorders, central nervous system disorders, bone disorders, inflammatory disorders, hyperproliferative disorders, disorders characterized by apoptosis and genetic disorders.
    • 本发明提供与生长素释放肽(生长激素促分泌素)受体结合和/或是功能性激动剂的大环化合物的新型盐和溶剂化物。 本发明还涉及这些盐和溶剂合物的多晶型物,含有这些盐或溶剂化物的药物组合物,以及使用该药物组合物的方法。 这些药物组合物可用作一系列疾病适应症,特别是用于治疗和预防胃肠道疾病的治疗剂,包括但不限于术后肠梗阻,胃轻瘫,包括糖尿病和手术后胃轻瘫,阿片样物质肠功能障碍, 梗阻,短肠综合征,功能性胃肠道疾病和胃肠动力障碍,例如与其他疾病状态一起发生,在重症监护情况下或作为药物治疗的结果。 此外,药物组合物可用于治疗和预防代谢和/或内分泌疾病,心血管疾病,中枢神经系统疾病,骨骼疾病,炎症性疾病,过度增殖性疾病,以凋亡和遗传疾病为特征的疾病。
    • 7. 发明授权
    • Autonomous gravity-feed beverage dispenser with cooling device
    • 具有冷却装置的自动重力给料饮料机
    • US06442960B1
    • 2002-09-03
    • US09830583
    • 2001-09-10
    • Eric FournierJean-Marc Ritter
    • Eric FournierJean-Marc Ritter
    • B67D562
    • B67D1/07B67D1/0867B67D1/0869B67D3/0009B67D2210/00026F25D31/003
    • A gravity-feed unit that dispenses cool drinks form a carboy includes a breakable inner seal. The carboy is supported by its neck, which is centered on a striker. The striker includes a discharge passage for the carboy that communicates with a coiled pipe to cause the beverage to flow through a secondary exchanger. A heat transferring agent is previously cooled in a primary exchanger and brought to the secondary exchanger by a pump. Actuation is controlled by a temperature sensor that measures the temperature of the heat transfer agent in the secondary exchanger. The primary exchanger includes a heat source that causes the heat transfer agent to pass continuously inside a closed circuit mutually connecting the primary and secondary exchangers regardless of whether the pump is operating.
    • 分配冷饮料的重力进料单元包含一个易碎的内部密封件。 它的颈部支撑着它的脖子,它以前锋为中心。 撞击器包括用于与线圈管连通以使饮料流过二次交换器的碳罐的排放通道。 传热剂预先在主交换器中冷却并通过泵送到二次交换器。 致动由温度传感器控制,温度传感器测量二次换热器中传热剂的温度。 主要交换器包括热源,其导致传热剂连续地通过相互连接初级和次级换热器的闭合回路,而不管泵是否运行。