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1. 发明授权

US08311185B2 Multi-energy x-ray source 有权
标题翻译：多能量X射线源
公开(公告)号：US08311185B2
公开(公告)日：2012-11-13
申请号：US12684069
申请日：2010-01-07
申请人： Edward J. Seppi , Gary Virshup
发明人： Edward J. Seppi , Gary Virshup
IPC分类号： H05G1/64
CPC分类号： H01J35/101 , A61B5/7289 , A61B5/7292 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/482 , A61B6/502 , A61B6/5288 , A61B6/541 , H01J35/14 , H01J35/28 , H01J35/305 , H01J2235/088 , H01J2235/1006
摘要： A system for generating image data includes a voltage supply configured for applying a first voltage to generate radiation at a first energy level, and for applying a second voltage to generate radiation at a second energy level, an imager for generating a first set of image data based at least in part on the radiation at the first energy level, and for generating a second set of image data based at least in part on the radiation at the second energy level, and a processor for creating composite image data using the first and the second sets of image data.
摘要翻译：一种用于产生图像数据的系统包括：电压源，被配置为施加第一电压以产生处于第一能级的辐射，并且用于施加第二电压以产生第二能量级的辐射;成像器，用于产生第一组图像数据至少部分地基于第一能量级别的辐射，以及用于至少部分地基于第二能级的辐射产生第二组图像数据，以及处理器，用于使用第一和第二能量水平产生合成图像数据第二组图像数据。

2. 发明授权

US07869862B2 Systems and methods for functional imaging using contrast-enhanced multiple-energy computed tomography 有权
标题翻译：使用对比度增强多能计算机断层扫描的功能成像的系统和方法
公开(公告)号：US07869862B2
公开(公告)日：2011-01-11
申请号：US10687522
申请日：2003-10-15
申请人： Edward J. Seppi , Larry Partain , Michael Green , Gary Virshup
发明人： Edward J. Seppi , Larry Partain , Michael Green , Gary Virshup
IPC分类号： A61B6/00
CPC分类号： A61B6/405 , A61B5/7289 , A61B5/7292 , A61B6/032 , A61B6/0435 , A61B6/4035 , A61B6/4042 , A61B6/4241 , A61B6/4441 , A61B6/4488 , A61B6/466 , A61B6/481 , A61B6/482 , A61B6/502 , A61B6/504 , A61B6/5288 , A61B6/541 , G01N23/046 , G01N2223/419 , G01N2223/612 , H01J2235/081
摘要： A method of generating images of a portion of a body includes introducing a contrast agent into the body, generating a first set of image data using radiation at a first energy level after the contrast agent is introduced into the body, generating a second set of image data using radiation at a second energy level after the contrast agent is introduced into the body, and creating a volumetric composite image using the first and the second sets of image data.
摘要翻译：产生身体部分的图像的方法包括将造影剂引入体内，在将造影剂引入体内之后，以第一能量级别的辐射产生第一组图像数据，产生第二组图像在将造影剂引入身体之后，使用在第二能量级别的辐射的数据，以及使用第一和第二组图像数据创建体积合成图像。

3. 发明授权

US07397904B2 Asymmetric flattening filter for x-ray device 有权
标题翻译：用于x射线装置的非对称平坦化滤光片
公开(公告)号：US07397904B2
公开(公告)日：2008-07-08
申请号：US11127343
申请日：2005-05-11
申请人： Gary Virshup , James Boye , Edward J. Seppi , Heinrich Riem , Govin Dasani , Edward Shapiro
发明人： Gary Virshup , James Boye , Edward J. Seppi , Heinrich Riem , Govin Dasani , Edward Shapiro
IPC分类号： G21K3/00
CPC分类号： G21K1/10
摘要： Devices and methods for implementing selective, or asymmetric, attenuation of an x-ray beam. In one example, a filter is provided that is substantially in the form of a wedge where some portions of the filter are thicker, and thus provide greater attenuation, than other, thinner portions of the filter. The filter is situated between the target surface of the anode and the x-ray subject so that x-rays generated by the target pass through the filter before reaching the x-ray subject. Specifically, the filter is oriented so that the thicker portion of the filter receives the higher intensity portion of the x-ray beam, while the thinner portion of the filter receives the relatively lower intensity portion of the x-ray beam. Thus, the gain profile of the x-ray beam is flattened so that the intensity, or flux, of the x-ray beam is relatively uniform throughout a substantial portion of the beam profile.
摘要翻译：用于实现X射线束的选择性或不对称衰减的装置和方法。在一个示例中，提供基本上为楔形件的过滤器，其中过滤器的一些部分比过滤器的其它较薄部分更厚，因此提供更大的衰减。过滤器位于阳极的目标表面和X射线对象之间，使得由目标产生的x射线在到达x射线物体之前通过过滤器。具体地，过滤器被定向成使得过滤器的较厚部分接收x射线束的较高强度部分，而过滤器的较薄部分接收x射线束的较低强度部分。因此，x射线束的增益分布被平坦化，使得x射线束的强度或通量在光束轮廓的整个实质部分中相对均匀。

4. 发明授权

US07649981B2 Multi-energy x-ray source 有权
标题翻译：多能量X射线源
公开(公告)号：US07649981B2
公开(公告)日：2010-01-19
申请号：US10687573
申请日：2003-10-15
申请人： Edward J. Seppi , Gary Virshup
发明人： Edward J. Seppi , Gary Virshup
IPC分类号： G21K3/00
CPC分类号： H01J35/101 , A61B5/7289 , A61B5/7292 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/482 , A61B6/502 , A61B6/5288 , A61B6/541 , H01J35/14 , H01J35/28 , H01J35/305 , H01J2235/088 , H01J2235/1006
摘要： An apparatus for use in a radiation procedure includes a radiation filter having a first portion and a second portion, the first and the second portions forming a layer for filtering radiation impinging thereon, wherein the first portion is made from a first material having a first x-ray filtering characteristic, and the second portion is made from a second material having a second x-ray filtering characteristic. An apparatus for use in a radiation procedure includes a first target material, a second target material, and an accelerator for accelerating particles towards the first target material and the second target material to generate x-rays at a first energy level and a second energy level, respectively.
摘要翻译：用于辐射过程的装置包括具有第一部分和第二部分的辐射过滤器，第一和第二部分形成用于过滤辐射的辐射层，其中第一部分由具有第一部分和第二部分的第一材料制成，射线滤波特性，第二部分由具有第二x射线滤波特性的第二材料制成。用于辐射过程的装置包括：第一靶材料，第二靶材料和用于将颗粒朝向第一靶材料加速的加速器和第二靶材料，以在第一能级和第二能级产生X射线，分别。

5. 发明授权

US08466421B2 Radiation detector with multiple operating schemes 有权
标题翻译：具有多种操作方案的辐射探测器
公开(公告)号：US08466421B2
公开(公告)日：2013-06-18
申请号：US12847569
申请日：2010-07-30
申请人： Gary Virshup , Edward Seppi , James Clayton , Edward G Shapiro
发明人： Gary Virshup , Edward Seppi , James Clayton , Edward G Shapiro
IPC分类号： G01T1/20
CPC分类号： G01T1/208 , G01T1/2018 , G01V5/0016 , G01V5/005
摘要： A radiation detector includes a conversion element that converts an incoming radiation beam into electrical signals, which in turn can be used to generate data about the radiation beam. The conversion element may include, for example, a scintillator that converts the radiation beam into light, and a sensor that generates the signals in response to the light. The conversion element can be used in different schemes or data collection modes. For instance, the conversion element can be oriented normal to the radiation beam or transverse to the radiation beam. In either of these orientations, for example, the detector can be used in an integrating mode or in a counting mode.
摘要翻译：辐射检测器包括将输入的辐射束转换成电信号的转换元件，该信号又可用于产生关于辐射束的数据。转换元件可以包括例如将辐射束转换成光的闪烁器，以及响应于光产生信号的传感器。转换元件可以用于不同的方案或数据收集模式。例如，转换元件可以垂直于辐射束或横向于辐射束。在这些取向中的任何一个中，例如，检测器可以以积分模式或计数模式使用。

6. 发明申请

US20100128839A1 Structure and Procedure for X-Ray CT Guided Cancer Treatment 审中-公开
标题翻译： X射线CT引导癌症治疗的结构和程序
公开(公告)号：US20100128839A1
公开(公告)日：2010-05-27
申请号：US12275819
申请日：2008-11-21
申请人： Larry D. Partain , Gary Virshup , Edward Seppi , David Humber
发明人： Larry D. Partain , Gary Virshup , Edward Seppi , David Humber
IPC分类号： A61N5/10 , H05G1/60
CPC分类号： A61N5/1048 , A61N2005/1061
摘要： A radiation apparatus includes a first radiation source configured to generate radiation suitable for therapeutic treatment, and a structure for supporting a body. The structure comprises a curved surface adapted to receive a body portion to be treated during a therapeutic treatment.
摘要翻译：辐射装置包括被配置为产生适于治疗性治疗的辐射的第一辐射源和用于支撑身体的结构。该结构包括适于在治疗性治疗期间接收待治疗的身体部分的弯曲表面。

7. 发明申请

US20060256925A1 Asymmetric flattening filter for x-ray device 有权
标题翻译：用于x射线装置的非对称平坦化滤光片
公开(公告)号：US20060256925A1
公开(公告)日：2006-11-16
申请号：US11127343
申请日：2005-05-11
申请人： Gary Virshup , James Boye , Edward Seppi , Heinrich Riem , Govin Dasani , Edward Shapiro
发明人： Gary Virshup , James Boye , Edward Seppi , Heinrich Riem , Govin Dasani , Edward Shapiro
IPC分类号： G21K3/00
CPC分类号： G21K1/10
摘要： Devices and methods for implementing selective, or asymmetric, attenuation of an x-ray beam. In one example, a filter is provided that is substantially in the form of a wedge where some portions of the filter are thicker, and thus provide greater attenuation, than other, thinner portions of the filter. The filter is situated between the target surface of the anode and the x-ray subject so that x-rays generated by the target pass through the filter before reaching the x-ray subject. Specifically, the filter is oriented so that the thicker portion of the filter receives the higher intensity portion of the x-ray beam, while the thinner portion of the filter receives the relatively lower intensity portion of the x-ray beam. Thus, the gain profile of the x-ray beam is flattened so that the intensity, or flux, of the x-ray beam is relatively uniform throughout a substantial portion of the beam profile.
摘要翻译：用于实现X射线束的选择性或不对称衰减的装置和方法。在一个示例中，提供基本上为楔形件的过滤器，其中过滤器的一些部分比过滤器的其它较薄部分更厚，因此提供更大的衰减。过滤器位于阳极的目标表面和X射线对象之间，使得由目标产生的x射线在到达x射线物体之前通过过滤器。具体地，过滤器被定向成使得过滤器的较厚部分接收x射线束的较高强度部分，而过滤器的较薄部分接收x射线束的较低强度部分。因此，x射线束的增益分布被平坦化，使得x射线束的强度或通量在光束轮廓的整个实质部分中相对均匀。

8. 发明申请

US20060119427A1 Data signal amplifier and processor with multiple signal gains for increased dynamic signal range 有权
公开(公告)号：US20060119427A1
公开(公告)日：2006-06-08
申请号：US11283422
申请日：2005-11-18
申请人： Pieter Roos , Edward Seppi , Richard Colbeth , Gary Virshup , Ivan Mollov
发明人： Pieter Roos , Edward Seppi , Richard Colbeth , Gary Virshup , Ivan Mollov
IPC分类号： H03F1/36
CPC分类号： H03F3/08 , H03M1/18
摘要： Data signal amplification and processing circuitry with multiple signal gains for increasing dynamic signal range. An incoming data signal is processed in accordance with multiple signal gains. The resultant signals have multiple signal values which are compared to predetermined lower and higher thresholds. The desired output signal is: the maximum sample signal value when the maximum value fails to traverse a predetermined lower threshold; the minimum sample signal value when an adjacent larger one of the plurality of sample signal values traverses a predetermined higher threshold; a smaller of mutually adjacent ones of a pair of the plurality of sample signal values when a larger one of the pair of sample signal values traverses the predetermined higher threshold and the smaller value fails to traverse the predetermined lower threshold; and a combination of the smaller and larger ones of the pair of sample signal values when the larger value traverses the predetermined lower threshold and fails to traverse the predetermined higher threshold.

9. 发明申请

US20120082294A1 X-RAY SYSTEM AND METHOD 审中-公开
标题翻译： X射线系统和方法
公开(公告)号：US20120082294A1
公开(公告)日：2012-04-05
申请号：US12896848
申请日：2010-10-02
申请人： Gary Virshup , Robert Kluge , George A. Zdasiuk , Richard Colbeth , Josh Star-Lack , Carl Lacasce , James E. Clayton
发明人： Gary Virshup , Robert Kluge , George A. Zdasiuk , Richard Colbeth , Josh Star-Lack , Carl Lacasce , James E. Clayton
IPC分类号： G01N23/04
CPC分类号： H05G1/56 , A61B6/405 , A61B6/4233 , A61B6/54 , A61B6/56 , H05G1/30 , H05G1/66
摘要： An x-ray system includes an x-ray tube having an anode and a cathode, a sensor configured to sense a condition that results from an operation of the x-ray tube, and a communication device for transmitting a signal to a panel based at least in part on the sensed condition, the panel configured to receive radiation and generate image signals in response to the received radiation. An imaging method includes sensing a condition that results from an operation of an x-ray tube, and transmitting a signal to a panel in response to the sensed condition, wherein the panel is configured to generate image signals in response to radiation, and includes a plurality of image elements.
摘要翻译： X射线系统包括具有阳极和阴极的x射线管，被配置为感测由X射线管的操作产生的状况的传感器，以及用于基于至少部分地基于所感测的状况，所述面板被配置为响应于所接收的辐射而接收辐射并产生图像信号。成像方法包括：感测由X射线管的操作产生的状况，以及响应于感测到的状况将信号发送到面板，其中面板被配置为响应于辐射而产生图像信号，并且包括多个图像元素。

10. 发明申请

US20100080337A1 Methods, Systems, and Computer-Program Products to Correct Degradation in Tomographic Images Caused by Extraneous Radiation 有权
标题翻译：方法，系统和计算机程序产品，以纠正由外来辐射引起的断层图像的退化
公开(公告)号：US20100080337A1
公开(公告)日：2010-04-01
申请号：US12239699
申请日：2008-09-26
申请人： Edward Seppi , Edward Shapiro , Gary Virshup , Josh Star-Lack
发明人： Edward Seppi , Edward Shapiro , Gary Virshup , Josh Star-Lack
IPC分类号： G21K1/00 , H05G1/60
CPC分类号： G21K1/10 , A61B6/00 , A61B6/4291
摘要： Disclosed are systems, methods, and computer program products that generate estimates of errors caused by extraneous radiation in tomographic systems, such as cone-beam computerized tomography (CBCT) systems, fluoroscopic tomography systems, radiographic tomography systems, laminar tomography imaging systems, and the like. In one group of inventions, spatial errors are estimated from projection data collected where a known spatial perturbation has been introduced into radiation intensity of the source. In another group of inventions, temporal errors are estimated from a sequence of projections where a known perturbation in the radiation intensity of the source for different projections has been introduced.
摘要翻译：公开了系统，方法和计算机程序产品，其产生在层析成像系统中由外部辐射引起的误差的估计，诸如锥束计算机断层摄影（CBCT）系统，荧光透视断层摄影系统，放射照相层析成像系统，层析成像系统，以及喜欢。在一组发明中，空间误差是从收集的投影数据估计的，其中已知的空间扰动已被引入到源的辐射强度。在另一组发明中，根据已经引入了用于不同投影的源的辐射强度的已知扰动的一系列投影来估计时间误差。

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