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    • 9. 发明授权
    • Adjustable prosthetic valve implant
    • 可调式假体瓣膜植入物
    • US08449604B2
    • 2013-05-28
    • US12544163
    • 2009-08-19
    • Shawn MoaddebSamuel ShaolianEmanuel ShaoulianJay A. Lenker
    • Shawn MoaddebSamuel ShaolianEmanuel ShaoulianJay A. Lenker
    • A61F2/24
    • A61F2/2469A61F2/07A61F2/2418A61F2/2445A61F2/90A61F2002/075A61F2210/0023A61F2220/0008A61F2220/0016A61F2220/005A61F2220/0058A61F2230/0078A61F2250/0004A61F2250/0007A61F2250/001
    • A prosthetic implant for treating a diseased aortic valve is described. The prosthetic implant includes a substantially tubular body configured to be positioned in an aorta of a patient, at or near the patient's aortic valve. The body includes a lumen extending through the body from a proximal end to a distal end of the body; and an adjustable frame surrounding the lumen. The prosthetic implant further includes at least one adjustable element located in or on the body and extending at least partially around a circumference of the lumen. The at least one adjustable element includes a shape memory material and is transformable, in response to application of an activation energy, from a first configuration to a second configuration, wherein the first configuration and second configuration differ in a size of at least one dimension of the at least one adjustable element. The at least one adjustable element may engage at least one of a root of the aorta, an annulus of the aortic valve, and the patient's left ventricle, when the at least one adjustable element is in the second configuration.
    • 描述了用于治疗患病主动脉瓣的假体植入物。 假体植入物包括构造成位于患者的主动脉中的基本上管状的主体,位于患者的主动脉瓣处或附近。 主体包括从身体的近端延伸穿过主体的内腔到远端; 以及围绕管腔的可调节框架。 假体植入物还包括至少一个位于体内或身体上的可调节元件,并且至少部分地围绕内腔的圆周延伸。 所述至少一个可调节元件包括形状记忆材料,并且响应于施加激活能量而可从第一配置转变为第二配置,其中所述第一配置和第二配置的尺寸至少为 所述至少一个可调元件。 当至少一个可调节元件处于第二构造时,至少一个可调元件可接合主动脉的根部,主动脉瓣的环和患者的左心室中的至少一个。