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    • 5. 发明授权
    • Opto-acoustic transducer for medical applications
    • 用于医疗应用的光学传感器
    • US06379325B1
    • 2002-04-30
    • US09350494
    • 1999-07-09
    • William BenettPeter CelliersLuiz Da SilvaMichael GlinskyRichard LondonDuncan MaitlandDennis MatthewsPeter KrulevichAbraham Lee
    • William BenettPeter CelliersLuiz Da SilvaMichael GlinskyRichard LondonDuncan MaitlandDennis MatthewsPeter KrulevichAbraham Lee
    • A61B1720
    • A61B18/26A61B17/2202A61B2017/00106A61B2017/22084A61B2090/378
    • This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control.
    • 本发明是用于在生物介质中产生声振动的光学激活换能器。 传感器位于可以位于导管内的光纤的端部。 用于操作换能器的能量由通过光纤传输到换能器的激光光学地提供。 脉冲激光被吸收在换能器的工作流体中,以产生热压力并随之导致换能器头部的绝热膨胀,使其对环境介质起作用。 传感器通过热冷却过程返回到其原始状态。 传感器在环境介质中的运动将声能耦合到介质中。 通过以高重复率脉冲激光(其可以从CW变化到100kHz),可以在介质中局部地建立超声辐射场。 这种生产超声波振动的方法可以在体内用于治疗人类中风相关病症,特别是用于溶解血栓。 导管还可以掺入抗血栓溶解药物治疗作为辅助治疗,并且其可以与用于成像和反馈控制的超声波检测设备结合操作。