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1. 发明申请

US20050003994A1 Surface-active compositions 失效
标题翻译：表面活性组合物
公开(公告)号：US20050003994A1
公开(公告)日：2005-01-06
申请号：US10901733
申请日：2004-07-29
申请人： Dietmar Ochs , Francois Brugger , Marcel Schnyder
发明人： Dietmar Ochs , Francois Brugger , Marcel Schnyder
IPC分类号： D06L1/12 , A01N25/02 , A01N31/08 , A01N31/16 , A61K8/00 , A61K8/33 , A61K8/40 , A61K8/46 , A61K8/60 , A61Q5/02 , A61Q19/10 , C11D1/04 , C11D1/90 , C11D3/00 , C11D3/20 , C11D3/34 , C11D3/48 , C11D17/06 , C11D17/08 , D06M13/156 , D06M13/165 , D06M13/256 , C11D7/18
CPC分类号： C11D3/48 , C11D3/2068
摘要： A surface-active composition is described which comprises (a) from 0.01 to 90% by weight of a mixture of a microbicidal active ingredient of (a1) a diphenyl ether compound and (a2) a phenol derivative, (b) from 0 to 50% by weight of one or more hydrotropic agents, (c) from 0 to 80% by weight of one or more synthetic detergents or of a soap or of combinations of the mentioned substances and/or of a salt of a saturated and/or unsaturated C8-C22 fatty acid, (d) from 0 to 50% by weight of an alcohol, (e) from 0 to 50% by weight of typical ingredients for cleaning and disinfectant compositions and optionally (f) tap water or deionised water ad 100%. The compositions are used for the antimicrobial treatment of human skin and hair, of hard surfaces and of textile fibre materials.
摘要翻译：描述了一种表面活性组合物，其包含（a）0.01至90重量％的（a1）二苯醚化合物的杀微生物活性成分和（a2）苯酚衍生物的混合物，（b）0至50 （c）0至80重量％的一种或多种合成洗涤剂或皂或所述物质的组合和/或饱和和/或不饱和的盐的组合 C8-C22脂肪酸，（d）0-50重量％的醇，（e）0-50重量％的用于清洁和消毒组合物的典型成分，以及任选地（f）自来水或去离子水ad 100 ％。该组合物用于人类皮肤和毛发，硬表面和纺织纤维材料的抗微生物处理。

2. 发明授权

US06759423B2 4-Hydroxyisothiazole compounds 失效
标题翻译： 4-羟基异噻唑化合物
公开(公告)号：US06759423B2
公开(公告)日：2004-07-06
申请号：US09969738
申请日：2001-10-03
申请人： Werner Hölzl , Wolfgang Haap , Dietmar Ochs , Karin Puchtler , Marcel Schnyder , Dinesh Narendra Rele , Sitaram Pal , Asawari Bhikaji Mahtre , Surendra Umesh Kulkarni , Arakali Srinivasarao Radhakrishna
发明人： Werner Hölzl , Wolfgang Haap , Dietmar Ochs , Karin Puchtler , Marcel Schnyder , Dinesh Narendra Rele , Sitaram Pal , Asawari Bhikaji Mahtre , Surendra Umesh Kulkarni , Arakali Srinivasarao Radhakrishna
IPC分类号： C07D47117
CPC分类号： C07D275/03 , A01N43/80 , Y10T442/2525
摘要： The present invention relates to the use of 4-hydroxyisothiazole compounds as antimicrobially active substances, certain new 4-hydroxyisothiazole compounds and a process for their preparation.
摘要翻译：本发明涉及4-羟基异噻唑化合物作为抗微生物活性物质的用途，某些新的4-羟基异噻唑化合物及其制备方法。

3. 发明授权

US06358906B1 Concentrated liquid accumulations comprising a microbicidally active ingredient 失效
标题翻译：浓缩液体制剂包含杀微生物活性成分
公开(公告)号：US06358906B1
公开(公告)日：2002-03-19
申请号：US09194801
申请日：1998-12-02
申请人： Dietmar Ochs , Marcel Schnyder
发明人： Dietmar Ochs , Marcel Schnyder
IPC分类号： C11D348
CPC分类号： A61Q17/005 , A01N25/02 , A01N31/16 , A61K8/33 , A61K8/34 , A61K8/347 , A61K8/58 , A61Q11/00 , A61Q15/00 , A61Q19/00 , C11D3/2003 , C11D3/2044 , C11D3/2075 , C11D3/2082 , C11D3/24 , C11D3/3418 , C11D3/48 , C11D7/261 , C11D7/265 , C11D7/28 , C11D7/34 , D06M13/144 , D06M13/148 , D06M13/152 , D06M13/165 , D06M13/188 , D06M13/192 , D06M13/203 , D06M13/207 , D06M13/256 , D06M16/00 , A01N2300/00
摘要： There are described concentrated liquid formulations (a) comprising (a1) 1 to 80% by weight of a microbicidally active ingredient, (a2) 20 to 99% by weight of a mono- or dihydric alcohol or mixtures thereof, and concentrated liquid formulations (b) comprising (b1) 5.1 to 30% by weight of microbicidally active ingredient, (b2) 0 to 80% by weight of sulfonate, (b3) 1 to 60% by weight of a C1-C11monocarboxylic acid or of a C3-C12di- or -polycarboxylic acid; (b4) 0 to 90% by weight of a mono- or dihydric alcohol or mixtures thereof, and water to 100%, it always being necessary for one of the components (b2) or (b4) to be present. The formulations according to the invention are used as microbicidally active ingredient in cosmetic products, household articles or hand disinfectants, as preservatives in household articles and cosmetic products and as disinfectant and decontamination agent for textile fibre materials or the skin and hard surfaces.
摘要翻译：描述了浓缩液体制剂（a），其包含（a1）1至80重量％的杀微生物活性成分，（a2）20至99重量％的一价或二元醇或其混合物和浓缩液体制剂（b ），（b1）5.1〜30重量％的杀微生物活性成分，（b2）0〜80重量％的磺酸盐，（b3）1〜60重量％的C1-C11单羧酸或C3-C12- 或 - 多羧酸;（b4）0-90％（重量）的一元醇或二元醇或其混合物，并且水至100％时，总是需要一种组分（b2）或（b4）。根据本发明的制剂用作化妆品，家用制品或手消毒剂中的杀微生物活性成分，作为家用制品和化妆品中的防腐剂，以及用作纺织纤维材料或皮肤和硬表面的消毒剂和去污剂。

4. 发明授权

US06346260B1 Microbicidal active ingredients 失效
标题翻译：杀菌活性成分
公开(公告)号：US06346260B1
公开(公告)日：2002-02-12
申请号：US09629416
申请日：2000-08-01
申请人： Werner Hölzl , Wolfgang Haap , Dietmar Ochs , Karin Puchtler , Marcel Schnyder
发明人： Werner Hölzl , Wolfgang Haap , Dietmar Ochs , Karin Puchtler , Marcel Schnyder
IPC分类号： A01N4340
CPC分类号： A01N43/10 , A01N35/04 , A01N37/42 , A01N43/40
摘要： The use of hydroxyphenyl-1,3-propanediones of formula: wherein R1 and R2 are each independently of the other hydrogen, C1-C12alkyl, C1-C12alkoxy, trifluoro-C1-C3alkyl, phenyl or halogen; R3 is a 5- or 6-membered heteroaromatic radical; thiophenyl; or a radical of formula: R4, R5, R6 and R7 are each independently of the other hydrogen, halogen, C1-C12alkyl, C1-C12alkoxy, carboxy or trifluoro-C1-C3alkyl; in the antimicrobial treatment of surfaces, is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and molds.
摘要翻译：使用下式的羟基苯基-1,3-丙二酮：其中R 1和R 2各自独立于另一个氢，C 1 -C 12烷基，C 1 -C 12烷氧基，三氟-C 1 -C 3烷基，苯基或卤素; R 3是5-或6- 元杂芳基; 噻吩基; 或者式R 4，R 5，R 6和R 7基团各自独立地为氢，卤素，C 1 -C 12烷基，C 1 -C 12烷氧基，羧基或三氟-C 1 -C 3烷基;在表面的抗微生物处理中。化合物表现出对病原性革兰氏阳性和革兰氏阴性细菌以及酵母和霉菌的显着作用。

5. 发明授权

US06743940B2 4-aminobut-2-ynecarboxylic acid derivatives 失效
标题翻译： 4-氨基丁-2-炔酸衍生物
公开(公告)号：US06743940B2
公开(公告)日：2004-06-01
申请号：US10016542
申请日：2001-12-13
申请人： Werner Hölzl , Wolfgang Haap , Jürgen Koppold , Dietmar Ochs , Karin Petzold , Marcel Schnyder
发明人： Werner Hölzl , Wolfgang Haap , Jürgen Koppold , Dietmar Ochs , Karin Petzold , Marcel Schnyder
IPC分类号： C07C22900
CPC分类号： C07C229/30
摘要： There are described 4-aminobut-2-ynecarboxylic acid derivatives of formula wherein R1 and R2 are each independently of the other hydrogen, C1-C20alkyl; C3-C12cycloalkyl; unsubstituted or C1-C5alkyl-, C3-C12cycloalkyl-, C1-C5alkoxy-, C3-C12cycloalkoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C12cycloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl, phenyl-C1-C5alkyl, naphthyl and naphthyl-C1-C5alkyl; and R3 is C1-C20alkyl; C3-C12cycloalkyl. The compounds exhibit a pronounced activity against gram-positive and gram-negative bacteria, and also against yeasts and moulds.
摘要翻译：描述了通式为R 1的4-氨基丁-2-炔酸衍生物，R 2各自独立地为氢，C 1 -C 20烷基; C 3 -C 12环烷基; 未取代的或C 1 -C 5烷基 - ，C 3 -C 12环烷基 - ，C 1 -C 5烷氧基 - ，C 3 -C 12环烷氧基 - ，卤代 - ，氧代 - ，羧基 - ，羧基-C 1 -C 7烷基酯 - ，羧基-C 3 -C 12环烷基酯 - 氰基 - 三氟甲基 - ，五氟乙基 - ，氨基 - ，N，N-单或二-C 1 -C 20烷基氨基或硝基取代的苯基，苯基-C 1 -C 5烷基，萘基和萘基-C 1 -C 5烷基; 和R 3是C 1 -C 20烷基; C3-C12环烷基。化合物对革兰氏阳性和革兰氏阴性细菌以及酵母和霉菌都表现出明显的活性。

6. 发明授权

US07041631B2 Surface-active compositions comprising a mixture of diphenyl ether and o-phenyl pheno 失效
标题翻译：包含二苯基醚和邻苯基苯酚的混合物的表面活性组合物
公开(公告)号：US07041631B2
公开(公告)日：2006-05-09
申请号：US10901733
申请日：2004-07-29
申请人： Dietmar Ochs , François Brugger , Marcel Schnyder
发明人： Dietmar Ochs , François Brugger , Marcel Schnyder
IPC分类号： C11D3/48
CPC分类号： C11D3/48 , C11D3/2068
摘要： A surface-active composition is described which comprises (a) from 0.01 to 90% by weight of a mixture of a microbicidal active ingredient of (a1) a diphenyl ether compound and (a2) a phenol derivative, (b) from 0 to 50% by weight of one or more hydrotropic agents, (c) from 0 to 80% by weight of one or more synthetic detergents or of a soap or of combinations of the mentioned substances and/or of a salt of a saturated and/or unsaturated C8–C22 fatty acid, (d) from 0 to 50% by weight of an alcohol, (e) from 0 to 50% by weight of typical ingredients for cleaning and disinfectant compositions and optionally (f) tap water or deionised water ad 100%. The compositions are used for the antimicrobial treatment of human skin and hair, of hard surfaces and of textile fibre materials.
摘要翻译：描述了一种表面活性组合物，其包含（a）0.01至90重量％的（a 1 SUB）二苯基醚化合物的杀微生物活性成分和（a 2 S 2 苯酚衍生物，（b）0至50重量％的一种或多种水溶助长剂，（c）0至80重量％的一种或多种合成洗涤剂或皂或其组合所述物质和/或饱和和/或不饱和的C 8 -C 22脂肪酸的盐，（d）0至50重量％的醇，（e）0至50重量％的用于清洁和消毒组合物的典型成分，以及任选地（f）100％自来水或去离子水。该组合物用于人类皮肤和毛发，硬表面和纺织纤维材料的抗微生物处理。

7. 发明授权

US06846492B2 Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces 失效
标题翻译：苯乙胺衍生物用于表面抗微生物处理
公开(公告)号：US06846492B2
公开(公告)日：2005-01-25
申请号：US10204520
申请日：2001-02-13
申请人： Wolfgang Haap , Werner Hölzl , Dietmar Ochs , Karin Petzold , Marcel Schnyder
发明人： Wolfgang Haap , Werner Hölzl , Dietmar Ochs , Karin Petzold , Marcel Schnyder
IPC分类号： A01N33/10 , A01N37/38 , A01N39/00 , A01N39/02 , A01N39/04 , C07C217/60 , C07C255/54 , A01N25/00 , A61K7/075 , A61K7/50 , C11D7/00 , D06L1/00
CPC分类号： C07C255/54 , A01N33/10 , A01N37/38 , A01N39/00 , A01N39/02 , A01N39/04 , C07C217/60 , C07C2601/08
摘要： The use of compounds of formula (1) is described, in which compounds R1, R2 and R3 are each independently of the others hydrogen; C1-C20alkyl; C3-C7cycloalkyl; C2-C20alkenyl; C4-C7cycloalkenyl; C2-C20alkynyl, C4-C7cycloalkynyl; or unsubstituted or C1-C5alkyl-, C3-C7cylcoalkyl-, C1-C5alkoxyl-, C3-C7cycloakoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C7cylcloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl-C1-C5alkyl, naphthyl-C1-C5alkyl, phenylcarbonyl-C1-C5alkyl, naphthylcarbonyl-C1-C5alkyl, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl, thiophenyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, 1,2,3-oxadiazolyl, 1,3,4-oxadiazolyl, 1,2,3-thiadiazolyl, 1,3,4-thiadiazolyl, indolyl, pyridyl, pyridazinyl, pyrimidinyl, pyridazinyl, quinolinyl or isoquinolinyl; R4, R5, R6 and R7 are each independently of the others hydrogen; C1-C20alkyl; C3-C7 cycloalky; C2-C20alkenyl; C4-C7 cycloalkenyl; C2-C20alkynyl; or C4-C7 cycloalkynyl; and m and n are each independently of the other 0 or 1, for antimicrobial treatment of surfaces. The compounds exhibit a pronounced activity against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. They are accordingly suitable for the antimicrobial treatment, especially preservation and disinfection, of surfaces.
摘要翻译：描述了式（1）化合物的用途，其中化合物R1，R2和R3各自独立地为氢; C1-C20烷基; C 3 -C 7环烷基; C2-C20烯基; C4-C7环烯基; C 2 -C 20炔基，C 4 -C 7环炔基; 或未取代的或C 1 -C 5烷基 - ，C 3 -C 7烷基烷基 - ，C 1 -C 5烷氧基 - ，C 3 -C 7环烷氧基 - ，卤代 - ，氧代 - ，羧基 - ，羧基-C 1 -C 7烷基酯 - ，羧基-C 3 -C 7环烷基酯 - 氰基 - 三氟甲基 - ，五氟乙基 - ，氨基 - ，N，N-单或二-C 1 -C 20烷基氨基或硝基取代的苯基-C 1 -C 5烷基，萘基-C 1 -C 5烷基，苯基羰基-C 1 -C 5烷基，萘基羰基-C 1 -C 5烷基，吡咯基烷基，呋喃基烷基，噻吩基烷基，吡唑基烷基，咪唑基烷基，恶唑基烷基，噻唑基烷基，异恶唑基烷基，异噻唑基烷基，1,2,3-三唑基烷基，1,2,4-三唑基烷基，1,2,3-恶二唑基烷基，1,3,4-恶二唑基烷基 1,2,3-噻二唑基烷基，1,3,4-噻二唑基烷基，吲哚基烷基，吡啶基烷基，哒嗪基烷基，嘧啶基烷基，哒嗪基烷基，喹啉基烷基，异喹啉基烷基，吡咯基，呋喃基，噻吩基，吡唑基，咪唑基，恶唑基，噻唑基，异恶唑基，异噻唑基，，2,3-三唑基，1,2,4-三唑基，1,2,3-恶二唑基，1,3,4-恶二唑基，1,2,3-噻二唑基，1,3,4-噻二唑基，吲哚基，吡啶基，哒嗪基，嘧啶基，哒嗪基，喹啉基或异喹啉基; R4，R5，R6和R7各自独立地为氢; C1-C20烷基; C3-C7环烷基; C2-C20烯基; C4-C7环烯基; C2-C20炔基; 或C 4 -C 7环炔基; m和n各自独立地为0或1，用于表面的抗微生物处理。该化合物显示出对病原性革兰氏阳性的显着活性

8. 发明申请

US20080058393A1 Fungicidal Detergent Compositions 失效
标题翻译：杀菌剂组合物
公开(公告)号：US20080058393A1
公开(公告)日：2008-03-06
申请号：US10593227
申请日：2005-03-14
申请人： Elizabeth Harumi Kobara Pestell , Marcel Schnyder , Francois Brugger , Fernand Hoffstetter
发明人： Elizabeth Harumi Kobara Pestell , Marcel Schnyder , Francois Brugger , Fernand Hoffstetter
IPC分类号： A01N43/78
CPC分类号： A01N43/78 , A01N31/16 , A01N2300/00
摘要： Disclosed is the use of the compound of formula whereinR1 is hydrogen; or C1-C5alkyl for the fungicidal treatment of hard surfaces and textile fibre materials.The compounds of formula (1) impart antifungal properties to washed textile material. Bacteria that get on the textile material while it is being worn are destroyed.
摘要翻译：公开了下式化合物其中R 1是氢的用途; 或C 1 -C 5烷基，用于硬表面和纺织纤维材料的杀真菌处理。式（1）的化合物赋予洗涤的纺织材料抗真菌性能。磨损时纺织材料上的细菌被破坏。

9. 发明授权

US07105577B2 Antimicrobial method using a hydroxydiphenyl ether compound 失效
标题翻译：使用羟基二苯醚化合物的抗微生物方法
公开(公告)号：US07105577B2
公开(公告)日：2006-09-12
申请号：US10816967
申请日：2004-04-02
申请人： Werner Hölzl , Wolfgang Haap , Dietmar Ochs , Karin Puchtler , Marcel Schnyder , Surendra Umesh Kulkarni , Arakali Srinivasarao Radhakrishna , Mangesh Shivram Sawant , Asawari Bhikaji Mahtre
发明人： Werner Hölzl , Wolfgang Haap , Dietmar Ochs , Karin Puchtler , Marcel Schnyder , Surendra Umesh Kulkarni , Arakali Srinivasarao Radhakrishna , Mangesh Shivram Sawant , Asawari Bhikaji Mahtre
IPC分类号： A61K31/075 , A61K31/12
CPC分类号： A01N31/16 , A01N35/04 , A61K8/347 , A61K8/35 , A61Q5/02 , A61Q11/00 , A61Q15/00 , A61Q17/005 , A61Q19/10 , C07C43/295 , C07C45/46 , C07C45/54 , C07C45/673 , C07C47/575 , C07C49/84 , C11D3/48 , C11D7/263 , C11D7/3227 , Y10S514/88 , Y10S514/881 , Y10S514/901
摘要： The present invention relates to the use of hydroxydiphenyl ether compounds as antimicrobially active substances, to certain new compounds of this type and to processes for the preparation of these compounds.
摘要翻译：本发明涉及羟基二苯醚化合物作为抗微生物活性物质的某些新型化合物和这些化合物的制备方法。

10. 发明授权

US06624182B1 Hydroxyphenylvinylthiazoles 失效
标题翻译：羟基苯基乙烯基噻唑
公开(公告)号：US06624182B1
公开(公告)日：2003-09-23
申请号：US09714716
申请日：2000-11-16
申请人： Wolfgang Haap , Werner Hölzl , Dietmar Ochs , Karin Puchtler , Marcel Schnyder
发明人： Wolfgang Haap , Werner Hölzl , Dietmar Ochs , Karin Puchtler , Marcel Schnyder
IPC分类号： A61K31425
CPC分类号： C07D277/22 , A01N43/78 , C07D277/24
摘要： The use of hydroxyphenylvinylthiazoles of formula wherein R1, R2, R3 and R4 are each independently of the others hydrogen; halogen; hydroxy, C1-C16-alkyl, C1-C16alkoxy, phenyl; phenyl-C1-C3alkyl; C6-C10aryloxy, amino, mono-C1-C5alkyl-amino, di-C1-C5alkylamino or -NO2; wherein at least one of the radicals R1, R2, R3 and R4 is hydroxy; R5 is C1-C5alkyl; C1-C5alkoxy; or unsubstituted or halo-, C1-C5alkyl-, C1-C5alkoxy-, hydroxy- or pyrrolidinyl-substituted phenyl; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. Accordingly, they are suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.
摘要翻译：使用羟基苯基乙烯基噻唑的化合物R1，R2，R3和R4各自独立地为氢; 卤素; 羟基，C 1 -C 16 - 烷基，C 1 -C 16烷氧基，苯基; 苯基-C 1 -C 3烷基; C 1 -C 10芳氧基，氨基，单-C 1 -C 5烷基 - 氨基，二-C 1 -C 5烷基氨基或-NO 2; 其中基团R 1，R 2，R 3和R 4中的至少一个是羟基; R 5是C 1 -C 5烷基; C1-C5烷氧基; 或未取代或卤代 - ，C 1 -C 5烷基 - ，C 1 -C 5烷氧基 - ，羟基 - 或吡咯烷基 - 取代的苯基; 作为杀微生物活性成分被描述。该化合物对病原性革兰氏阳性和革兰氏阴性细菌以及酵母和霉菌都表现出明显的作用。因此，它们适用于抗菌处理，特别是表面的保存和消毒。

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