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    • 3. 发明授权
    • Aerosol container and a method for storage and administration of a pre-determined amount of a pharmaceutically active aerosol
    • 气溶胶容器和用于储存和施用预定量的药学活性气溶胶的方法
    • US08119105B2
    • 2012-02-21
    • US10424633
    • 2003-04-28
    • Francois BruggerAngelika Stampf
    • Francois BruggerAngelika Stampf
    • A61K9/12A61M11/00
    • A61K9/008B65D83/54
    • The invention relates to an aerosol container for pharmaceutically active aerosols that are to be administered in predetermined amounts and that are supplied in the container in the form of a suspension, the suspension also comprising, in addition to a pharmaceutically active substance, at least a propellant gas. The aerosol container has a metering valve that comprises a metering chamber and a valve stem. In a first position of the valve stem, the metering chamber is in communication with the interior of the container and has been filled with a predetermined amount of the aerosol. In a second position of the valve stem, the amount of aerosol disposed in the metering chamber is released. The propellant gas is an alternative propellant gas that is free of fluorochlorohydrocarbons, preferably a propellant gas that comprises only fluorohydrocarbons, and the inner wall of the container is coated with a plastics coating.
    • 本发明涉及一种用于药物活性气溶胶的气溶胶容器,其以预定量施用并以悬浮液的形式供应到容器中,所述悬浮液除药学活性物质外还包含至少一种推进剂 加油站。 气溶胶容器具有包括计量室和阀杆的计量阀。 在阀杆的第一位置中,计量室与容器的内部连通,并且已经填充有预定量的气溶胶。 在阀杆的第二位置,释放设置在计量室中的气溶胶的量。 推进剂气体是不含氟氯代烃的替代推进剂气体,优选仅包含氟代烃的推进剂气体,并且容器的内壁涂覆有塑料涂层。