专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08728979B2 Method for identifying cells based on DNA replication domain timing profiles 有权
标题翻译：基于DNA复制域定时分布识别细胞的方法
公开(公告)号：US08728979B2
公开(公告)日：2014-05-20
申请号：US12200186
申请日：2008-08-28
申请人： David M. Gilbert , Tyrone Ryba , Ichiro Hiratani
发明人： David M. Gilbert , Tyrone Ryba , Ichiro Hiratani
IPC分类号： C40B30/04 , C12Q1/68
CPC分类号： C12Q1/6837 , C12Q1/6804 , C12Q1/6806 , C12Q1/6809 , G01N33/5005 , C12Q2565/626 , C12Q2565/501 , C12Q2525/101
摘要： Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.
摘要翻译：提供了基于使用高分辨率基因组阵列或测序程序的复制域时序概况来识别和/或区分同源细胞群的方法。这些方法可用于将细胞群体的复制定时概况与复制定时指纹，复制定时指纹和/或复制定时指纹的一个或多个信息段进行比较，其可以同时或先前确定和/或包含在数据库中，以确定它们之间是否存在匹配。基于这样的信息，可以确定细胞群体的身份，或者细胞群体的身份可以与其他细胞群体或细胞类型区分开。还提供了用于确定特定细胞类型的复制定时指纹的方法。

2. 发明申请

US20120322675A1 GENOME-SCALE ANALYSIS OF REPLICATION TIMING 审中-公开
标题翻译：复制时间的基因量化分析
公开(公告)号：US20120322675A1
公开(公告)日：2012-12-20
申请号：US13479686
申请日：2012-05-24
申请人： David M. Gilbert , Tyrone Ryba , Ichiro Hiratani
发明人： David M. Gilbert , Tyrone Ryba , Ichiro Hiratani
IPC分类号： C40B30/04 , G06F19/20
CPC分类号： C12Q1/6809 , C12Q1/6841 , C12Q1/6881 , C12Q2600/158 , C12Q2527/113 , C12Q2531/149 , C12Q2539/115 , C12Q2565/501
摘要： Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.
摘要翻译：提供了基于使用高分辨率基因组阵列或测序程序的复制域时序概况来识别和/或区分同源细胞群的方法。这些方法可用于将细胞群体的复制定时概况与复制定时指纹，复制定时指纹和/或复制定时指纹的一个或多个信息段进行比较，其可以同时或先前确定和/或包含在数据库中，以确定它们之间是否存在匹配。基于这样的信息，可以确定细胞群体的身份，或者细胞群体的身份可以与其他细胞群体或细胞类型区分开。还提供了用于确定特定细胞类型的复制定时指纹的方法。

3. 发明授权

US09245090B2 Fingerprint for cell identity and pluripotency 有权
标题翻译：指纹用于细胞识别和多能性
公开(公告)号：US09245090B2
公开(公告)日：2016-01-26
申请号：US13595017
申请日：2012-08-27
申请人： David M. Gilbert , Tyrone Ryba , Jinfeng Zhang
发明人： David M. Gilbert , Tyrone Ryba , Jinfeng Zhang
IPC分类号： G06F19/10 , G06F19/00 , G06F19/24
CPC分类号： G06F19/24
摘要： A method for determining a replication timing footprint comprises the following steps: (a) selecting a set of chosen regions of the replication timing profile of a chromosome of an individual, (b) choosing a set of selected regions from the set of chosen regions to form a set of selected regions and a set of unused regions, (c) conducting a iterative algorithm on the set of selected regions until a domain number for the set of selected regions has decreased to a predetermined minimum, (d) determining a replication timing footprint based the set of selected regions after step (c) has been conducted, and (e) displaying the replication timing footprint to a user.
摘要翻译：一种用于确定复制定时覆盖区的方法包括以下步骤：（a）选择个体染色体的复制定时分布的一组选定区域，（b）从所选择的区域组中选择一组选定区域，形成一组所选择的区域和一组未使用的区域，（c）对所选区域的集合进行迭代算法，直到所选择的区域集合的域号已经减小到预定的最小值，（d）确定复制定时已经执行步骤（c）之后的所选区域集合的占位面积，以及（e）向用户显示复制定时覆盖区。

4. 发明授权

US08725423B2 Replication timing profiles for leukemia and other cancers 有权
标题翻译：白血病和其他癌症的复制时机
公开(公告)号：US08725423B2
公开(公告)日：2014-05-13
申请号：US13726803
申请日：2012-12-26
申请人： David M. Gilbert , Tyrone Ryba
发明人： David M. Gilbert , Tyrone Ryba
IPC分类号： G06F19/26
CPC分类号： G06F19/26 , G06F19/18 , G06F19/24
摘要： Described is a method for determining that a population of cells are a specific type of leukemic cell based on the replication timing fingerprint for the population of cells.
摘要翻译：描述了基于细胞群体的复制时间指纹来确定细胞群体是特定类型的白血病细胞的方法。

5. 发明申请

US20120062917A1 MASS CUSTOMIZATION OF ARTICLES HAVING DIMENSIONAL AND/OR ANIMATED IMAGES 有权
标题翻译：具有尺寸和/或动画图像的文章的大规模定制
公开(公告)号：US20120062917A1
公开(公告)日：2012-03-15
申请号：US13231387
申请日：2011-09-13
申请人： Daniel S. Hirsch , David M. Gilbert , John Tomczyk , Anthony L. Hoffman
发明人： Daniel S. Hirsch , David M. Gilbert , John Tomczyk , Anthony L. Hoffman
IPC分类号： G06K1/00
CPC分类号： B41M3/00 , B42D15/02 , B42D15/027 , B42D2035/20 , G02B27/123 , G02B27/2214 , G06F3/1203 , G06F3/1243 , G06K15/105
摘要： Mass customization of articles with a customized composite or dimensional image created from one or more custom images, such as photographs, text, and the like. The customized composite image is automatically generated by interlacing, or otherwise combining, the one or more custom or personalized images, and is automatically placed or imposed in a digital template to form a print ready file. The print file is then digitally printed on a substrate and a lens is married thereto such that the composite image is viewable through the lens. Alternatively, the print ready file, or at least the customized composite image, is printed directly on the back of a lens such that the composite image is viewable through the lens.
摘要翻译：使用由一个或多个自定义图像创建的自定义复合或维度图像（如照片，文本等）大量自定义文章。定制的合成图像通过交织或以其他方式组合一个或多个定制或个性化图像而自动生成，并且被自动放置或施加在数字模板中以形成打印准备文件。然后将打印文件数字印刷在基板上，并且透镜与其结合，使得合成图像可透过透镜观看。或者，打印准备文件或至少定制的合成图像直接印在透镜的背面上，使得合成图像可通过透镜观看。

6. 发明申请

US20080112761A1 IN SITU REMEDIATION OF SOURCE ZONES VIA IN SITU ADMIXING OF CONTAMINATED MEDIA, CHEMICAL OXIDANTS, AND STABILIZING AGENTS 审中-公开
标题翻译：在污染介质，化学氧化物和稳定剂的初步加工中，通过原位改造源区
公开(公告)号：US20080112761A1
公开(公告)日：2008-05-15
申请号：US11737599
申请日：2007-04-19
申请人： Thomas Clay Sale , David M. Gilbert
发明人： Thomas Clay Sale , David M. Gilbert
IPC分类号： B09C1/08
CPC分类号： B09C1/08
摘要： A process for treating contaminants present in subsurface source zones comprises in situ admixing of contaminated media, chemical oxidants and stabilizing agents using known soil-mixing techniques. A grout for treating contaminants present in soil comprises chemical oxidants and stabilizing agents.
摘要翻译：用于处理存在于地下源区中的污染物的方法包括使用已知的土壤混合技术原位混合受污染的介质，化学氧化剂和稳定剂。用于处理土壤中污染物的灌浆剂包括化学氧化剂和稳定剂。

7. 发明授权

US4396932A Method for making a light-activated line-operable zero-crossing switch including two lateral transistors, the emitter of one lying between the emitter and collector of the other 失效
标题翻译：用于制造具有两个横向晶体管的光激活线路可操作的零交叉开关的方法，一个位于另一个的发射极和集电极之间的发射极
公开(公告)号：US4396932A
公开(公告)日：1983-08-02
申请号：US288861
申请日：1981-07-31
申请人： Paul G. Alonas , David M. Gilbert , Vernon P. O'Neil, II
发明人： Paul G. Alonas , David M. Gilbert , Vernon P. O'Neil, II
IPC分类号： H01L27/07 , H01L27/144 , H01L29/747 , H03K17/79
CPC分类号： H01L27/1443 , H01L27/0711 , H01L29/747 , H03K17/79 , Y10T307/773
摘要： A monolithic light-activated line-operable zero-crossing switch and method of making the same. The device comprises anti-parallel thyristors, each of whose gates is shunted by a field effect transistor. Each device may also be shunted by a resistor to reduce the overall sensitivity. The method of making the device contemplates surrounding the field effect transistor gate electrode and an internal shunt electrode by the primary metallization which forms the contact to the two main terminals of the device.
摘要翻译：单片光激活线路可操作的零交叉开关及其制造方法。该装置包括反并联晶闸管，其每个栅极由场效应晶体管分流。每个器件还可以由电阻器分流以降低总体灵敏度。制造该器件的方法考虑通过与器件的两个主端子形成接触的初级金属化来围绕场效应晶体管栅电极和内部分流电极。

8. 发明授权

US09132691B2 Mass customization of articles having dimensional and/or animated images 有权
标题翻译：具有尺寸和/或动画图像的物品的大规模定制
公开(公告)号：US09132691B2
公开(公告)日：2015-09-15
申请号：US13231387
申请日：2011-09-13
申请人： Daniel S. Hirsch , David M. Gilbert , John Tomczyk , Anthony L. Hoffman
发明人： Daniel S. Hirsch , David M. Gilbert , John Tomczyk , Anthony L. Hoffman
IPC分类号： H04N1/46 , B42D15/02
CPC分类号： B41M3/00 , B42D15/02 , B42D15/027 , B42D2035/20 , G02B27/123 , G02B27/2214 , G06F3/1203 , G06F3/1243 , G06K15/105
摘要： Mass customization of articles with a customized composite or dimensional image created from one or more custom images, such as photographs, text, and the like. The customized composite image is automatically generated by interlacing, or otherwise combining, the one or more custom or personalized images, and is automatically placed or imposed in a digital template to form a print ready file. The print file is then digitally printed on a substrate and a lens is married thereto such that the composite image is viewable through the lens. Alternatively, the print ready file, or at least the customized composite image, is printed directly on the back of a lens such that the composite image is viewable through the lens.
摘要翻译：使用由一个或多个自定义图像创建的自定义复合或维度图像（如照片，文本等）大量自定义文章。定制的合成图像通过交织或以其他方式组合一个或多个定制或个性化图像而自动生成，并且被自动放置或施加在数字模板中以形成打印准备文件。然后将打印文件数字印刷在基板上，并且透镜与其结合，使得合成图像可透过透镜观看。或者，打印准备文件或至少定制的合成图像直接印在透镜的背面上，使得合成图像可通过透镜观看。

9. 发明授权

US5898128A Electronic component 失效
标题翻译：电子元器件
公开(公告)号：US5898128A
公开(公告)日：1999-04-27
申请号：US712037
申请日：1996-09-11
申请人： Guillermo L. Romero , Christopher M. Scanlan , David M. Gilbert
发明人： Guillermo L. Romero , Christopher M. Scanlan , David M. Gilbert
IPC分类号： H01L23/538 , H01L25/07 , H01L25/16 , H05K1/05 , H05K1/18 , H05K3/10 , H05K5/00
CPC分类号： H01L24/82 , H01L23/5389 , H01L24/24 , H01L25/072 , H01L25/16 , H05K1/053 , H05K1/183 , H05K5/0091 , H01L2224/05554 , H01L2224/24137 , H01L2224/24227 , H01L2224/48091 , H01L2224/49111 , H01L24/48 , H01L2924/00014 , H01L2924/01004 , H01L2924/01006 , H01L2924/01013 , H01L2924/01024 , H01L2924/01029 , H01L2924/01033 , H01L2924/01042 , H01L2924/01047 , H01L2924/01074 , H01L2924/01078 , H01L2924/01079 , H01L2924/014 , H01L2924/14 , H01L2924/351 , H05K2201/0376 , H05K2201/09036 , H05K2201/09981 , H05K2201/10969 , H05K2203/049 , H05K3/107
摘要： An electronic component (10) has an electrically insulating substrate (20) that is encapsulated with an electrically conductive material (15) to provide thermal dissipation for the electronic component (10). The electrically insulating substrate (20) has cavities (21-24) that are either completely filled with an electrically conductive material (15) or are partially filled to provide recesses (26-27) for electronic devices (30,31). The electronic devices (30,31) are electrically coupled to the leads (60-63) of the electronic component (10) using either wire bonds (70) or metallic depositions (55-57).
摘要翻译：电子部件（10）具有用导电材料（15）封装以提供电子部件（10）的散热的电绝缘基板（20）。电绝缘基板（20）具有完全填充有导电材料（15）的腔体（21-24），或者部分地被填充以提供用于电子设备（30,31）的凹槽（26-27）。电子器件（30,31）使用引线键（70）或金属沉积（55-57）电耦合到电子元件（10）的引线（60-63）。

10. 发明授权

US4458408A Method for making a light-activated line-operable zero-crossing switch 失效
标题翻译：用于制造光激活的线路可操作的过零开关的方法
公开(公告)号：US4458408A
公开(公告)日：1984-07-10
申请号：US484080
申请日：1983-04-11
申请人： Paul G. Alonas , David M. Gilbert , Vernon P. O'Neil, II
发明人： Paul G. Alonas , David M. Gilbert , Vernon P. O'Neil, II
IPC分类号： H01L27/07 , H03K17/79 , H01L29/747
CPC分类号： H03K17/79 , H01L27/0711
摘要： A monolithic light-activated line-operable zero-crossing switch and method of making the same. The device comprises anti-parallel thyristors, each of whose gates is shunted by a field effect transistor. Each device may also be shunted by a resistor to reduce the overall sensitivity. The method of making the device contemplates surrounding the field effect transistor gate electrode and an internal shunt electrode by the primary metallization which forms the contact to the two main terminals of the device.
摘要翻译：单片光激活线路可操作的零交叉开关及其制造方法。该装置包括反并联晶闸管，其每个栅极由场效应晶体管分流。每个器件还可以由电阻器分流以降低总体灵敏度。制造该器件的方法考虑通过与器件的两个主端子形成接触的初级金属化来围绕场效应晶体管栅电极和内部分流电极。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式