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1. 发明授权

US06656428B1 Automated point of care detection system including complete sample processing capabilities 失效
标题翻译：自动点护理检测系统，包括完整的样品处理能力
公开(公告)号：US06656428B1
公开(公告)日：2003-12-02
申请号：US09632343
申请日：2000-08-03
申请人： David D. Clark , Jeffrey W. Steaffens , John Dorson , Ian Wells , Alan J. Fujii , James E. Maynard , James Baker , John Zeis , Charles Bickoff , Richard D. McEachern , Kunio Kohga , Andrew Ghusson , John C. Balsavich, Jr.
发明人： David D. Clark , Jeffrey W. Steaffens , John Dorson , Ian Wells , Alan J. Fujii , James E. Maynard , James Baker , John Zeis , Charles Bickoff , Richard D. McEachern , Kunio Kohga , Andrew Ghusson , John C. Balsavich, Jr.
IPC分类号： G01N2100
CPC分类号： B01L3/502 , B01L2200/16 , B01L2300/0672 , B01L2400/0478 , B01L2400/0644 , G01N35/00 , G01N35/1002 , G01N2035/0436 , G01N2035/0443 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： The present invention relates to cost effective analytical instruments for determining the presence or amount of an analyte in a sample. The analytical instruments utilize an assay cartridge which has a sample receiving port and a rotatable carousel containing a plurality of reagent wells. Each reagent well includes a piston element for delivery of reagent to a test surface. The instrument is capable of indexing the assay cartridge to deliver sample and reagents to a test surface in a predetermined and flexibile manner, thus providing an assay protocol which is specific to the type of sample under analysis. The invention also relates to components, features, disposables, reagent delivery systems, accessories, and methods for using such instruments. Appropriate applications include infectious disease testing, cancer detection and monitoring, therapeutic drug level monitoring, allergy testing, environmental testing, food testing, diagnostic testing of human and veterinary samples, and off-line process testing.
摘要翻译：本发明涉及用于确定样品中分析物的存在或量的成本有效的分析仪器。分析仪器使用具有样品接收端口和包含多个试剂阱的可旋转转盘的测定盒。每个试剂井都包括用于将试剂输送到测试表面的活塞元件。该仪器能够对分析盒进行分度，以将样品和试剂以预定和灵活的方式递送到测试表面，从而提供对所分析样品类型特异性的测定方案。本发明还涉及用于使用这些仪器的组件，特征，一次性用品，试剂递送系统，附件和方法。适当的应用包括传染病测试，癌症检测和监测，治疗药物水平监测，过敏测试，环境测试，食品测试，人类和兽医样品的诊断测试以及离线过程测试。

2. 发明申请

US20130018776A1 System and Method for Income Risk Assessment Utilizing Income Fraud and Income Estimation Models 审中-公开
标题翻译：利用收入欺诈和收入估算模型进行收入风险评估的制度与方法
公开(公告)号：US20130018776A1
公开(公告)日：2013-01-17
申请号：US13182228
申请日：2011-07-13
申请人： Jianjun Xie , Hoi-Ming Chi , Roger Noe , Mike Barnett , Brent Gaddis , James Baker
发明人： Jianjun Xie , Hoi-Ming Chi , Roger Noe , Mike Barnett , Brent Gaddis , James Baker
IPC分类号： G06Q40/02
CPC分类号： G06Q40/02
摘要： A method of income validation and evaluation for income risk assessment is disclosed in one embodiment. The method includes receiving a borrower loan request including a plurality of borrower data selected from the group consisting of: an employment type code, a borrower date-of-birth, a borrower zip code and a stated monthly income. The method further includes analyzing the received plurality of borrower data with respect to a stored plurality of borrower data to generate a normalized plurality of borrower data, implementing, if the stated monthly income is non-zero, an income fraud model utilizing at least the normalized plurality of borrower data including the employment type code, the borrower date-of-birth and the borrower zip code to determine an income fraud score based on the normalized plurality of borrower data, implementing an income estimation model utilizing at least the normalized plurality of borrower data and an age-band to determine a predicted income, and determining a risk assessment value as a function of the income fraud model and the income estimation mode.
摘要翻译：在一个实施例中公开了收入风险评估的收入确认和评估方法。该方法包括接收借款人贷款请求，其中包括从由以下各项组成的组中选择的多个借款人数据：雇佣类型代码，借款人出生日期，借款人邮政编码和所述月收入。该方法还包括分析所接收的多个借款人数据相对于所存储的多个借款人数据以产生归一化的多个借款人数据，如果所述月收入不为零，则实施至少使用归一化的收入欺诈模型多个借款人数据，包括就业类型代码，借款人出生日期和借款人邮政编码，以根据归一化的多个借款人数据确定收入欺诈分数，实施利用至少归一化的多个借款人的收入估计模型数据和年龄段来确定预测收入，以及确定风险评估值作为收入欺诈模型和收入估计模式的函数。

3. 发明申请

US20120190124A1 Reversible Covalent Linkage of Functional Molecules 有权
标题翻译：功能分子的可逆共价连接
公开(公告)号：US20120190124A1
公开(公告)日：2012-07-26
申请号：US13389625
申请日：2010-08-09
申请人： Mark Smith , Stephen Caddick , James Baker
发明人： Mark Smith , Stephen Caddick , James Baker
IPC分类号： C07K1/00 , C07D207/456 , C07K1/14 , C07D237/04 , G01N21/75 , C07K14/655 , C07D495/04
CPC分类号： C07K14/655 , A61K47/551 , A61K47/60 , A61K47/62 , A61K49/0017 , C07D207/416 , C07D207/456 , C07D209/52 , C07K14/435 , G01N33/58 , Y02P20/55
摘要： The present invention relates to the use of a compound containing a moiety of formula (I) as a reagent for linking a compound of formula R1—H which comprises a first functional moiety of formula F1 to a second functional moiety of formula F2 wherein X, X′, Y, R1, F1 and F2 are as defined herein. The present invention also provides related processes and products. The present invention is useful for creating functional conjugate compounds, and specifically conjugates in which at least one of the constituent molecules carries a thiol group.
摘要翻译：本发明涉及含有式（I）部分的化合物作为将包含式F1的第一功能部分的式R 1 -H的化合物与式F2的第二功能部分连接的试剂的用途，其中X， X'，Y，R1，F1和F2如本文所定义。本发明还提供了相关的方法和产品。本发明可用于产生功能性缀合化合物，特别是缀合物，其中至少一种构成分子携带巯基。

4. 发明申请

US20080045942A1 ELECTROSURGICAL INSTRUMENT AND METHOD OF USE 审中-公开
标题翻译：静电仪器及其使用方法
公开(公告)号：US20080045942A1
公开(公告)日：2008-02-21
申请号：US11925092
申请日：2007-10-26
申请人： CSABA TRUCKAI , James Baker , John Shaddock
发明人： CSABA TRUCKAI , James Baker , John Shaddock
IPC分类号： A61B18/12
CPC分类号： A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00148 , A61B2018/0063 , A61B2018/00654 , A61B2018/00791 , A61B2018/00797 , A61B2018/00809 , A61B2018/1467
摘要： An electrosurgical medical device and method for creating thermal welds in engaged tissue. In one embodiment, at least one jaw of the instrument defines a tissue engagement plane carrying a variable resistive body of a positive temperature coefficient material that has a selected decreased electrical conductance at each selected increased temperature thereof over a targeted treatment range. The variable resistive body can be engineered to bracket a targeted thermal treatment range, for example about 60° C. to 80° C., at which tissue welding can be accomplished. In one mode of operation, the engagement plane will automatically modulate and spatially localize ohmic heating within the engaged tissue from Rf energy application across micron-scale portions of the engagement surface. In another mode of operation, a variable resistive body will focus conductive heating in a selected portion of the engagement surface.
摘要翻译：一种用于在接合组织中产生热焊缝的电外科医疗装置和方法。在一个实施例中，仪器的至少一个钳口限定了携带正温度系数材料的可变电阻体的组织接合平面，其在目标治疗范围内的每个选定的升高温度下具有选定的降低的电导率。可变电阻体可以被设计成支撑目标热处理范围，例如约60℃至80℃，在该热处理范围内可以实现组织焊接。在一种操作模式中，接合平面将自动地调节并且在接合表面的微米级部分的Rf能量施加之间空间地定位所接合组织内的欧姆加热。在另一种操作模式中，可变电阻体将导电加热聚焦在接合表面的选定部分中。

5. 发明申请

US20070244980A1 Instant Messaging Plug-Ins 失效
标题翻译：即时通讯插件
公开(公告)号：US20070244980A1
公开(公告)日：2007-10-18
申请号：US11279865
申请日：2006-04-14
申请人： James Baker , Jennifer Bayer , John Holmes , Katrina Blanch , Wendy Cook
发明人： James Baker , Jennifer Bayer , John Holmes , Katrina Blanch , Wendy Cook
IPC分类号： G06F15/16
CPC分类号： G06Q10/107
摘要： Various embodiments provide a standardized way to interact with and extend instant messaging applications. A platform is provided and enables developers and other third parties to create extensions for instant messaging applications. Through a set of APIs, interacting applications or plug-ins are “sandboxed” in their own areas where they are unable to perform unpermitted or unauthorized actions. The plug-in platform or architecture is integrated with the platform of the instant messaging application and can allow developers to create plug-ins that can interact with a local user and their buddies. Any number of various types of plug-ins can be developed and incorporated into the instant messaging application in a standardized manner.
摘要翻译：各种实施例提供了与即时消息传递应用进行交互和延伸的标准化方式。提供了一个平台，使开发人员和其他第三方能够为即时消息应用程序创建扩展。通过一组API，交互应用程序或插件在他们无法执行未授权或未经授权的操作的区域中被“沙箱”。插件平台或架构与即时消息应用程序的平台集成在一起，可以让开发人员创建可以与本地用户及其伙伴进行交互的插件。可以开发任何数量的各种类型的插件，并以标准化方式将其并入即时消息应用程序。

6. 发明授权

US07226085B2 Guard for in-line roller skate 有权
标题翻译：守卫在线溜冰鞋
公开(公告)号：US07226085B2
公开(公告)日：2007-06-05
申请号：US11332267
申请日：2006-01-17
申请人： James Baker
发明人： James Baker
IPC分类号： A63C3/12
CPC分类号： A63C17/20 , A63C17/002 , A63C17/06 , A63C2201/02
摘要： The guard is formed of moldable, flexible material and has a number of wheel-receiving wells formed in an in-line configuration in its upper wall. The forward and rear edges of each well are located high enough to prevent a wheel from rolling forward or rearward within the well. Laterally extending grooves are formed in the wells to minimize forward and backward movement of the wheels within the wells while the side walls of the wells contact the side walls of the wheels in order to minimize lateral movement.
摘要翻译：防护件由可成型的柔性材料形成，并且在其上壁中具有以直列构型形成的多个轮收容井。每个井的前边缘和后边缘都足够高以防止砂轮在井内向前或向后滚动。在井中形成横向延伸的槽，以最小化井内的车轮的向前和向后运动，同时井的侧壁接触车轮的侧壁以便使侧向运动最小化。

7. 发明申请

US20070054834A1 Quaternary ammonium halides for treatment of infectious conditions 审中-公开
标题翻译：用于治疗感染性疾病的第四纪卤化铵
公开(公告)号：US20070054834A1
公开(公告)日：2007-03-08
申请号：US11400795
申请日：2006-04-10
申请人： James Baker
发明人： James Baker
IPC分类号： C11D3/00
CPC分类号： A61K31/14 , Y02A50/393 , Y02A50/469 , Y02A50/471 , Y02A50/478
摘要： Compositions comprising quaternary ammonium halides and methods of using the compositions comprising quaternary ammonium halides to treat and/or prevent infectious conditions in humans are provided.
摘要翻译：提供了包含季铵卤化物的组合物和使用包含季铵卤化物的组合物治疗和/或预防人体感染性病症的方法。

8. 发明申请

US20070036831A1 Nanoemulsion compositions having anti-inflammatory activity 审中-公开
标题翻译：具有抗炎活性的纳米乳剂组合物
公开(公告)号：US20070036831A1
公开(公告)日：2007-02-15
申请号：US11501007
申请日：2006-08-09
申请人： James Baker
发明人： James Baker
IPC分类号： A61K31/573 , A61K9/00
CPC分类号： A61K9/1075 , A61K31/573
摘要： Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, at least one anti-inflammatory agent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.
摘要翻译：描述了显示出微生物的广谱灭活或预防疾病的低毒性的纳米乳剂组合物。纳米乳剂含有水相，包含油和有机溶剂的油相，至少一种抗炎剂和一种或多种表面活性剂。还提供了制备纳米乳剂和灭活病原微生物的方法。

9. 发明授权

US07150744B2 Infusion array ablation apparatus 有权
公开(公告)号：US07150744B2
公开(公告)日：2006-12-19
申请号：US10700605
申请日：2003-11-03
申请人： Stuart D. Edwards , James Baker , Hugh Sharkey , Ronald G. Lax
发明人： Stuart D. Edwards , James Baker , Hugh Sharkey , Ronald G. Lax
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B18/1206 , A61B18/14 , A61B18/1402 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00026 , A61B2017/00084 , A61B2017/00101 , A61B2018/00011 , A61B2018/00023 , A61B2018/00196 , A61B2018/00273 , A61B2018/00452 , A61B2018/00476 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2018/1435 , A61B2018/1472 , A61B2018/162 , A61B2018/1861 , A61B2218/002 , A61M3/0279 , A61M25/007 , A61N1/06 , A61N1/403 , A61N5/02 , A61N5/04 , A61N5/045 , B22F2999/00 , C22C1/0491 , C22C14/00 , C22F1/183 , B22F3/1216 , C22C33/0285
摘要： An infusion array ablation apparatus includes an elongated delivery device having a lumen and an infusion array positionable in the lumen. The infusion array includes an RF electrode and at least a first and a second infusion member. Each infusion member has a tissue piercing distal portion and an infusion lumen. At least one of the first or second infusion members is positionable in the elongated delivery device in a compacted state and deployable from the elongated delivery device with curvature in a deployed state. Also, at least one of the first or second infusion members exhibits a changing direction of travel when advanced from the elongated delivery device to a selected tissue site. At least one infusion port is coupled to one of the elongated delivery device, the infusion array, the first infusion member or the second infusion member.

10. 发明申请

US20060277670A1 Urinary transfer system and associated method of use 有权
标题翻译：尿转移系统及相关使用方法
公开(公告)号：US20060277670A1
公开(公告)日：2006-12-14
申请号：US10526942
申请日：2004-12-02
申请人： Larry Baker , James Baker , Warren Spielman
发明人： Larry Baker , James Baker , Warren Spielman
IPC分类号： A47K11/00
CPC分类号： A61G9/006 , A61G9/00
摘要： There is a urinary transfer system and associated process that includes a urinal capable of receiving urine from a patient, urine holding container, a first conduit connected between the urinal and the urine holding container, a pump, and a second conduit connected between the urine holding container and the pump. Preferably, there is a retainer that is associated with the urinal and a removable lid associated with the urine holding container. The urinary transfer system can be powered by any type of electrical power supply and/or battery. Optimally, there is a receiver electrically connected to the pump to be able to turn the pump on and off and can preferably control the operation of the pump based on input received from a transmitter. An external male catheter can also be utilized in conjunction with the urinary transfer system.
摘要翻译：具有尿转移系统和相关联的方法，其包括能够从患者接收尿液的小便器，尿液容纳容器，连接在小便池和尿液保持容器之间的第一导管，泵和连接在尿液保持容器之间的第二导管容器和泵。优选地，存在与小便器相关联的保持器和与尿液保持容器相关联的可移除盖。尿转移系统可以由任何类型的电源和/或电池供电。最佳地，存在电连接到泵的接收器以能够打开和关闭泵，并且可以优选地基于从发射器接收的输入来控制泵的操作。外部阳性导管也可以与泌尿系统结合使用。

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