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1. 发明授权

US6004348A Endoluminal encapsulated stent and methods of manufacture and endoluminal delivery 失效
标题翻译：腔内胶囊支架及其制造方法和腔内输送
公开(公告)号：US6004348A
公开(公告)日：1999-12-21
申请号：US67158
申请日：1998-04-27
申请人： Christopher E. Banas , Tarun J. Edwin , David Dalessandro
发明人： Christopher E. Banas , Tarun J. Edwin , David Dalessandro
IPC分类号： A61F2/82 , A61F2/06
CPC分类号： A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075
摘要： An radially expandable stent-graft and method of making the same, including at least one a stent member encapsulated between at least two longitudinally expanded polytetrafluoroethylene (ePTFE) coverings. The at least one stent member has openings through wall surfaces of the stent to permit radial expansion. The at least two longitudinally expanded ePTFE coverings are circumferentially applied over the at least one stent member in their unsintered state, and sintered during application of a circumferential pressure to bond the ePTFE around and through the wall surfaces of the stent. The sintered ePTFE forms a substantially continuous, monolithic and integral encapsulation of the at least one stent. Upon radial expansion of the stent-graft, the stent and the ePTFE node-fibril microstructure radially deform. Radial deformation of the ePTFE encapsulation results in nodal elongation in the axis of radial expansion. After radial expansion of the stent-graft, a substantial bonded area remains intact and maintains the encapsulation of the stent in vivo.
摘要翻译：一种可径向扩张的支架移植物及其制造方法，包括至少一个封装在至少两个纵向膨胀的聚四氟乙烯（ePTFE）覆盖物之间的支架构件。至少一个支架构件具有通过支架的壁表面的开口以允许径向膨胀。所述至少两个纵向膨胀的ePTFE覆盖物在其未烧结状态下周向地施加在所述至少一个支架构件上，并且在施加周向压力下烧结以将ePTFE结合在支架的壁表面上并通过支架的壁表面。烧结的ePTFE形成至少一个支架的基本上连续的，整体的和整体的包封。在支架移植物的径向膨胀时，支架和ePTFE节点 - 原纤维微结构径向变形。 ePTFE封装的径向变形导致径向膨胀轴的节点伸长。在支架移植物的径向膨胀之后，实质的结合区域保持完整并且将体内的支架保持在囊内。

2. 发明授权

US08790241B2 Selective adherence of stent-graft coverings 有权
标题翻译：支架移植物覆盖物的选择性粘附
公开(公告)号：US08790241B2
公开(公告)日：2014-07-29
申请号：US13225028
申请日：2011-09-02
申请人： Tarun J. Edwin , Scott L. Randall , Brendan McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Scott L. Randall , Brendan McCrea , Christopher E. Banas
IPC分类号： A61F2/04 , A61F2/07 , A61F2/90
CPC分类号： A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/072 , A61F2002/075 , A61F2230/005 , A61F2230/0054 , A61F2240/001 , A61F2250/0003 , A61F2250/0014 , A61F2250/0039 , A61F2250/0067 , B29C65/02 , B29C65/48 , B29L2031/753
摘要： A method for making a radially expandable stent-graft, including positioning a radially expandable stent member concentrically over a first polymeric member, locating a second polymeric member concentrically over the stent member and first polymeric member, and joining the first polymeric member to the second polymeric member through interstices of the stent member at selective locations to form slip planes between the first and second polymeric members. The slip planes accommodate movement of the stent between the polymeric members to facilitate compression of the stent graft to a low profile.
摘要翻译：一种用于制造径向可扩张的支架移植物的方法，包括将径向可扩张的支架构件同心地定位在第一聚合物构件上，将第二聚合物构件同心地定位在支架构件和第一聚合构件上，以及将第一聚合物构件连接到第二聚合物通过在选择性位置处的支架构件的间隙以在第一和第二聚合物构件之间形成滑动平面。滑动平面适应支架在聚合物构件之间的运动，以便将支架移植物压缩至低轮廓。

3. 发明授权

US08617441B2 Methods for making an encapsulated stent 失效
标题翻译：制造胶囊支架的方法
公开(公告)号：US08617441B2
公开(公告)日：2013-12-31
申请号：US13399715
申请日：2012-02-17
申请人： Tarun J. Edwin , Christopher E. Banas , Brendan Mccrea
发明人： Tarun J. Edwin , Christopher E. Banas , Brendan Mccrea
IPC分类号： B29C45/14
CPC分类号： A61F2/82 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2002/072 , A61L27/507 , A61L31/048 , A61L31/10 , A61L2400/16 , B29C55/005 , B29C55/22 , B29K2027/18 , Y10S623/901 , C08L27/18
摘要： A method for making an encapsulated stent includes providing a first seamless unsintered ePTFE tube, providing a second seamless unsintered ePTFE tube, positioning a balloon-expandable stent between the first and second ePTFE tubes to form an assembly, disposing an ePTFE interlayer member between the first and second ePTFE tubes, and joining the first ePTFE tube to the second ePTFE tube through openings in a wall of the stent by applying first pressure, and then heat, to the assembly.
摘要翻译：制造胶囊化支架的方法包括提供第一无缝未烧结的ePTFE管，提供第二无缝未烧结的ePTFE管，将球囊扩张支架定位在第一和第二ePTFE管之间以形成组件，将ePTFE夹层构件设置在第一和第二ePTFE管，并且通过施加第一压力将第一ePTFE管连接到第二ePTFE管，通过支架的壁中的开口，然后加热到组件。

4. 发明授权

US08337650B2 Methods for making a supported graft 失效
标题翻译：制作支撑移植物的方法
公开(公告)号：US08337650B2
公开(公告)日：2012-12-25
申请号：US13434472
申请日：2012-03-29
申请人： Tarun J. Edwin , Rajagopal R. Kowligi , Brendan McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Rajagopal R. Kowligi , Brendan McCrea , Christopher E. Banas
IPC分类号： B32B37/00
CPC分类号： A61F2/88 , A61F2/0077 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/072 , A61F2002/075 , A61F2002/30093 , A61F2002/30448 , A61F2210/0019 , A61F2210/0076 , A61F2220/005 , A61L31/048 , C08L27/18
摘要： A method for forming a self-expanding stent-graft, including coupling a shape memory member to a polymer cladding to form a polymer clad member, disposing a length of the polymer clad member in an overlapping helical manner about a longitudinal axis, joining and sealing adjacent overlapping regions of the polymer clad member to form a stent-graft, manipulating the stent-graft from a first diameter to a second diameter smaller than the first diameter, and loading the stent-graft into a restraining sheath at the second diameter, the restraining sheath preventing expansion of the stent-graft from the second diameter to the first diameter.
摘要翻译：一种形成自扩张型支架移植物的方法，包括将形状记忆元件耦合到聚合物包层以形成聚合物包覆部件，将一段长度的聚合物包覆部件以围绕纵向轴线的重叠螺旋方式设置，接合和密封聚合物包覆部件的相邻重叠区域以形成支架移植物，将支架移植物从第一直径操纵至小于第一直径的第二直径，并将支架移植物装载到第二直径的约束护套中，限制护套防止支架移植物从第二直径扩展到第一直径。

5. 发明授权

US6053943A Endoluminal graft with integral structural support and method for making same 失效
标题翻译：具有整体结构支持的腔内移植物及其制备方法
公开(公告)号：US6053943A
公开(公告)日：2000-04-25
申请号：US77533
申请日：1998-05-28
申请人： Tarun J. Edwin , Christopher E. Banas
发明人： Tarun J. Edwin , Christopher E. Banas
IPC分类号： A61F2/00 , A61F2/06 , B29C47/00 , B29C53/14 , B29C53/58 , B29C55/22 , A61F2/04
CPC分类号： A61F2/07 , B29C47/0019 , B29C47/0023 , B29C47/003 , B29C47/0033 , B29C55/22 , A61F2/0077 , A61F2/848 , A61F2/88 , A61F2002/072 , A61F2002/8483 , A61F2220/0016 , B29C47/00 , B29C53/14 , B29C53/58 , B29L2031/753
摘要： A structurally supported graft (10) having a support structure (26) with strain relief sections (30) contained with an internal surface, an external surface, or a wall thickness of a tubular graft member (12). The structurally supported graft (10) may include a beading element (24) which is co-extruded with the support structure (26) having strain relief sections (30) and spiraled about the tubular graft (10). The support structure (26) includes differing types of strain relief sections (30) which are capable of allowing for the longitudinal and radial expansion of the structurally supported graft (10), respectively. The strain relief sections (30) may also include unconnected ends which form outwardly protruding barbs (62) upon expansion of the structurally supported graft within a blood vessel or body lumen. The method for making the structurally supported graft includes selecting or preparing a support structure with strain relief sections, co-extruding the structural support with a beading element, forming a spiral about the tubular graft with the co-extruded structure, and securing the co-extruded structure to the tubular graft.
摘要翻译： PCT No.PCT / US95 / 16497 Sec。 371日期：1998年5月28日 102（e）日期1998年5月28日PCT提交1995年12月8日PCT公布。公开号WO97 / 21401 日期：1997年6月19日具有支撑结构（26）的结构支撑的移植物（10）具有应变消除部分（30），其包含管状移植部件（12）的内表面，外表面或壁厚。结构支撑的移植物（10）可以包括与具有应变消除部分（30）并且围绕管状移植物（10）螺旋化的支撑结构（26）共挤出的卷边元件（24）。支撑结构（26）包括不同类型的应变消除部分（30），其能够分别允许结构支撑的移植物（10）的纵向和径向膨胀。应变消除部分（30）还可以包括在结构上支撑的移植物在血管或体腔内膨胀时形成向外突出的倒钩（62）的未连接的端部。用于制造结构支撑的移植物的方法包括选择或制备具有应变消除部分的支撑结构，将结构支撑件用滚珠元件共挤出，用共挤出结构在管状移植物周围形成螺旋，挤压结构到管状移植物。

6. 发明授权

US08157940B2 Methods for making a supported graft 有权
标题翻译：制作支撑移植物的方法
公开(公告)号：US08157940B2
公开(公告)日：2012-04-17
申请号：US12546483
申请日：2009-08-24
申请人： Tarun J. Edwin , Rajagopal R. Kowligi , Brendan McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Rajagopal R. Kowligi , Brendan McCrea , Christopher E. Banas
IPC分类号： B32B37/00
CPC分类号： A61F2/88 , A61F2/0077 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/072 , A61F2002/075 , A61F2002/30093 , A61F2002/30448 , A61F2210/0019 , A61F2210/0076 , A61F2220/005 , A61L31/048 , C08L27/18
摘要： A method for forming a self-expanding stent-graft, including coupling a shape memory member to a polymer cladding to form a polymer clad member, winding a length of the polymer clad member about a mandrel so that adjacent windings include regions of polymer cladding that overlap, heating the wound polymer clad member to join and seal the overlapping regions to one another, manipulating the stent-graft from a first diameter to a second diameter smaller than the first diameter, and loading the stent-graft into a restraining sheath, wherein the restraining sheath prevents the stent-graft from reverting to the first diameter.
摘要翻译：一种用于形成自扩张支架移植物的方法，包括将形状记忆元件耦合到聚合物包层以形成聚合物包覆部件，围绕心轴缠绕长度的聚合物包覆部件，使得相邻绕组包括聚合物包层的区域，重叠，加热缠绕的聚合物包覆部件以将重叠区域彼此连接并密封，将支架移植物从第一直径操作至小于第一直径的第二直径，并将支架移植物装载到限制鞘中，其中限制护套防止支架移植物恢复到第一直径。

7. 发明申请

US20110196473A1 METHODS FOR MAKING AN ENCAPSULATED STENT AND INTRALUMINAL DELIVERY THEREOF 失效
标题翻译：用于制造包封手套和其内分泌物的方法
公开(公告)号：US20110196473A1
公开(公告)日：2011-08-11
申请号：US13088129
申请日：2011-04-15
申请人： Brendan J. McCrea , Tarun J. Edwin , Christopher E. Banas
发明人： Brendan J. McCrea , Tarun J. Edwin , Christopher E. Banas
IPC分类号： A61F2/82 , B32B37/00
CPC分类号： A61F2/82 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2002/072 , A61L27/507 , A61L31/048 , A61L31/10 , A61L2400/16 , B29C55/005 , B29C55/22 , B29K2027/18 , Y10S623/901 , C08L27/18
摘要： A method for making an encapsulated stent includes providing a first seamless unsintered ePTFE tube, providing a second seamless sintered ePTFE tube, positioning a self-expanding stent between the first and second ePTFE tubes to form an assembly, disposing an ePTFE interlayer member between the first and second ePTFE tubes, and joining the first ePTFE tube to the second ePTFE tube through openings in a wall of the stent by applying first pressure, and then heat, to the assembly.
摘要翻译：制造胶囊化支架的方法包括提供第一无缝未烧结的ePTFE管，提供第二无缝烧结ePTFE管，将自扩张支架定位在第一和第二ePTFE管之间以形成组件，将ePTFE夹层部件设置在第一和第二ePTFE管，并且通过施加第一压力将第一ePTFE管连接到第二ePTFE管，通过支架的壁中的开口，然后加热到组件。

8. 发明授权

US06264684B1 Helically supported graft 失效
标题翻译：螺旋支持移植
公开(公告)号：US06264684B1
公开(公告)日：2001-07-24
申请号：US08999583
申请日：1997-12-22
申请人： Christopher E. Banas , Tarun J. Edwin , Brendan J. McCrea , Rajagopal R. Kowligi
发明人： Christopher E. Banas , Tarun J. Edwin , Brendan J. McCrea , Rajagopal R. Kowligi
IPC分类号： A61F206
CPC分类号： A61F2/88 , A61F2/0077 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/072 , A61F2002/075 , A61F2002/30093 , A61F2002/30448 , A61F2210/0019 , A61F2210/0076 , A61F2220/005 , A61L31/048 , C08L27/18
摘要： Shape memory alloy and elastically self-expanding endoluminal support structures which are at least partially encapsulated in a substantially monolithic expanded polytetrafluoroethylene (“ePTFE”) covering. An endoluminal stent, which has a reduced diametric dimension for endoluminal delivery and a larger in vivo final diametric diameter, is encapsulated in an ePTFE covering which circumferentially covers both the luminal and abluminal walls along at least a portion of the longitudinal extent of the endoluminal stent. The stent and ePTFE covering are helically wound into an open cylindrical configuration with adjacent windings forming overlapping regions of ePTFE covering bonded to one another. The shape memory endoluminal stent is fabricated from a shape memory alloy which exhibits either shape memory or pseudoelastic properties or from an elastic material having an inherent spring tension such as spring steel, braided stainless steel wire, or composite materials, such as woven or braided carbon fibers.
摘要翻译：形状记忆合金和弹性自膨胀腔内支撑结构，其至少部分地包封在基本上整齐的膨胀聚四氟乙烯（“ePTFE”）中。内窥镜支架具有减小的内腔输送的直径尺寸和较大的体内最终直径直径，被封装在ePTFE覆盖物中，沿着沿内腔支架的纵向范围的至少一部分圆周地覆盖管腔和囊腔壁。支架和ePTFE覆盖物螺旋缠绕成开放的圆柱形构造，相邻的绕组形成覆盖彼此结合的ePTFE的重叠区域。形状记忆腔内支架由具有形状记忆或假弹性特征的形状记忆合金或具有固有弹簧张力的弹性材料制成，例如弹簧钢，编织不锈钢丝或复合材料，例如织造或编织碳纤维。

9. 发明授权

US6124523A Encapsulated stent 失效
标题翻译：封装支架
公开(公告)号：US6124523A
公开(公告)日：2000-09-26
申请号：US401871
申请日：1995-03-10
申请人： Christopher E. Banas , Tarun J. Edwin
发明人： Christopher E. Banas , Tarun J. Edwin
IPC分类号： A61F2/06 , A61F2/02
CPC分类号： A61F2/07 , A61F2/90 , A61F2002/072
摘要： An encapsulated stent including a stent or structural support layer sandwiched between two biocompatible flexible layers. One preferred embodiment has a stent cover which includes a tubular shaped stent that is concentrically retained between two tubular shaped grafts of expanded polytetrafluoroethylene. Another preferred embodiment has a stent graft which includes at least one stent sandwiched between the ends of two tubular shaped grafts wherein at least a portion of the grafts are unsupported by the stent. Still another embodiment includes an articulating stented graft which includes a plurality of stents spaced apart from one another at a predetermined distance wherein each stent is contained between two elongated biocompatible tubular members. The graft/stent/graft assemblies all have inseparable layers.
摘要翻译：一种胶囊化支架，其包括夹在两个生物相容性柔性层之间的支架或结构支撑层。一个优选实施例具有支架盖，其包括同心地保持在膨胀聚四氟乙烯的两个管状移植物之间的管状支架。另一优选实施例具有支架移植物，其包括夹在两个管状移植物的端部之间的至少一个支架，其中移植物的至少一部分不被支架支撑。另一个实施例包括铰接式支架移植物，其包括以预定距离彼此间隔开的多个支架，其中每个支架包含在两个细长的生物相容性管状构件之间。移植物/支架/移植物组件都具有不可分离的层。

10. 发明授权

US5628786A Radially expandable vascular graft with resistance to longitudinal compression and method of making same 失效
标题翻译：具有抗纵向压缩的径向扩张血管移植物及其制造方法
公开(公告)号：US5628786A
公开(公告)日：1997-05-13
申请号：US439853
申请日：1995-05-12
申请人： Christopher E. Banas , Scott Randall , Tarun J. Edwin , Fariba Hurry
发明人： Christopher E. Banas , Scott Randall , Tarun J. Edwin , Fariba Hurry
IPC分类号： A61F2/00 , A61F2/06 , A61L27/16 , B32B1/08
CPC分类号： A61F2/07 , A61F2/06 , A61L27/16 , B32B1/08 , A61F2002/072 , A61F2002/075 , A61F2250/0018 , Y10S623/901 , Y10T428/31544
摘要： A microporous polytetrafluoroethylene ("PTFE") endovascular graft which has a reinforcing structure integrally bound to the graft which permits radial expansion of the graft and stabilizes the graft against longitudinal compression upon application of an axial force thereto and against axial foreshortening upon radial expansion of the graft. The graft is particularly useful as a covering for an endovascular stent.
摘要翻译：一种微孔聚四氟乙烯（“PTFE”）血管内移植物，其具有与移植物整体结合的增强结构，其允许移植物的径向膨胀，并且在施加轴向力时使移植物抵抗纵向压缩并且在径向扩张时防止轴向缩短接枝。移植物特别适用于血管内支架的覆盖物。

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