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1. 发明授权

US08790241B2 Selective adherence of stent-graft coverings 有权
标题翻译：支架移植物覆盖物的选择性粘附
公开(公告)号：US08790241B2
公开(公告)日：2014-07-29
申请号：US13225028
申请日：2011-09-02
申请人： Tarun J. Edwin , Scott L. Randall , Brendan McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Scott L. Randall , Brendan McCrea , Christopher E. Banas
IPC分类号： A61F2/04 , A61F2/07 , A61F2/90
CPC分类号： A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/072 , A61F2002/075 , A61F2230/005 , A61F2230/0054 , A61F2240/001 , A61F2250/0003 , A61F2250/0014 , A61F2250/0039 , A61F2250/0067 , B29C65/02 , B29C65/48 , B29L2031/753
摘要： A method for making a radially expandable stent-graft, including positioning a radially expandable stent member concentrically over a first polymeric member, locating a second polymeric member concentrically over the stent member and first polymeric member, and joining the first polymeric member to the second polymeric member through interstices of the stent member at selective locations to form slip planes between the first and second polymeric members. The slip planes accommodate movement of the stent between the polymeric members to facilitate compression of the stent graft to a low profile.
摘要翻译：一种用于制造径向可扩张的支架移植物的方法，包括将径向可扩张的支架构件同心地定位在第一聚合物构件上，将第二聚合物构件同心地定位在支架构件和第一聚合构件上，以及将第一聚合物构件连接到第二聚合物通过在选择性位置处的支架构件的间隙以在第一和第二聚合物构件之间形成滑动平面。滑动平面适应支架在聚合物构件之间的运动，以便将支架移植物压缩至低轮廓。

2. 发明授权

US08617441B2 Methods for making an encapsulated stent 失效
标题翻译：制造胶囊支架的方法
公开(公告)号：US08617441B2
公开(公告)日：2013-12-31
申请号：US13399715
申请日：2012-02-17
申请人： Tarun J. Edwin , Christopher E. Banas , Brendan Mccrea
发明人： Tarun J. Edwin , Christopher E. Banas , Brendan Mccrea
IPC分类号： B29C45/14
CPC分类号： A61F2/82 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2002/072 , A61L27/507 , A61L31/048 , A61L31/10 , A61L2400/16 , B29C55/005 , B29C55/22 , B29K2027/18 , Y10S623/901 , C08L27/18
摘要： A method for making an encapsulated stent includes providing a first seamless unsintered ePTFE tube, providing a second seamless unsintered ePTFE tube, positioning a balloon-expandable stent between the first and second ePTFE tubes to form an assembly, disposing an ePTFE interlayer member between the first and second ePTFE tubes, and joining the first ePTFE tube to the second ePTFE tube through openings in a wall of the stent by applying first pressure, and then heat, to the assembly.
摘要翻译：制造胶囊化支架的方法包括提供第一无缝未烧结的ePTFE管，提供第二无缝未烧结的ePTFE管，将球囊扩张支架定位在第一和第二ePTFE管之间以形成组件，将ePTFE夹层构件设置在第一和第二ePTFE管，并且通过施加第一压力将第一ePTFE管连接到第二ePTFE管，通过支架的壁中的开口，然后加热到组件。

3. 发明授权

US08337650B2 Methods for making a supported graft 失效
标题翻译：制作支撑移植物的方法
公开(公告)号：US08337650B2
公开(公告)日：2012-12-25
申请号：US13434472
申请日：2012-03-29
申请人： Tarun J. Edwin , Rajagopal R. Kowligi , Brendan McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Rajagopal R. Kowligi , Brendan McCrea , Christopher E. Banas
IPC分类号： B32B37/00
CPC分类号： A61F2/88 , A61F2/0077 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/072 , A61F2002/075 , A61F2002/30093 , A61F2002/30448 , A61F2210/0019 , A61F2210/0076 , A61F2220/005 , A61L31/048 , C08L27/18
摘要： A method for forming a self-expanding stent-graft, including coupling a shape memory member to a polymer cladding to form a polymer clad member, disposing a length of the polymer clad member in an overlapping helical manner about a longitudinal axis, joining and sealing adjacent overlapping regions of the polymer clad member to form a stent-graft, manipulating the stent-graft from a first diameter to a second diameter smaller than the first diameter, and loading the stent-graft into a restraining sheath at the second diameter, the restraining sheath preventing expansion of the stent-graft from the second diameter to the first diameter.
摘要翻译：一种形成自扩张型支架移植物的方法，包括将形状记忆元件耦合到聚合物包层以形成聚合物包覆部件，将一段长度的聚合物包覆部件以围绕纵向轴线的重叠螺旋方式设置，接合和密封聚合物包覆部件的相邻重叠区域以形成支架移植物，将支架移植物从第一直径操纵至小于第一直径的第二直径，并将支架移植物装载到第二直径的约束护套中，限制护套防止支架移植物从第二直径扩展到第一直径。

4. 发明授权

US6053943A Endoluminal graft with integral structural support and method for making same 失效
标题翻译：具有整体结构支持的腔内移植物及其制备方法
公开(公告)号：US6053943A
公开(公告)日：2000-04-25
申请号：US77533
申请日：1998-05-28
申请人： Tarun J. Edwin , Christopher E. Banas
发明人： Tarun J. Edwin , Christopher E. Banas
IPC分类号： A61F2/00 , A61F2/06 , B29C47/00 , B29C53/14 , B29C53/58 , B29C55/22 , A61F2/04
CPC分类号： A61F2/07 , B29C47/0019 , B29C47/0023 , B29C47/003 , B29C47/0033 , B29C55/22 , A61F2/0077 , A61F2/848 , A61F2/88 , A61F2002/072 , A61F2002/8483 , A61F2220/0016 , B29C47/00 , B29C53/14 , B29C53/58 , B29L2031/753
摘要： A structurally supported graft (10) having a support structure (26) with strain relief sections (30) contained with an internal surface, an external surface, or a wall thickness of a tubular graft member (12). The structurally supported graft (10) may include a beading element (24) which is co-extruded with the support structure (26) having strain relief sections (30) and spiraled about the tubular graft (10). The support structure (26) includes differing types of strain relief sections (30) which are capable of allowing for the longitudinal and radial expansion of the structurally supported graft (10), respectively. The strain relief sections (30) may also include unconnected ends which form outwardly protruding barbs (62) upon expansion of the structurally supported graft within a blood vessel or body lumen. The method for making the structurally supported graft includes selecting or preparing a support structure with strain relief sections, co-extruding the structural support with a beading element, forming a spiral about the tubular graft with the co-extruded structure, and securing the co-extruded structure to the tubular graft.
摘要翻译： PCT No.PCT / US95 / 16497 Sec。 371日期：1998年5月28日 102（e）日期1998年5月28日PCT提交1995年12月8日PCT公布。公开号WO97 / 21401 日期：1997年6月19日具有支撑结构（26）的结构支撑的移植物（10）具有应变消除部分（30），其包含管状移植部件（12）的内表面，外表面或壁厚。结构支撑的移植物（10）可以包括与具有应变消除部分（30）并且围绕管状移植物（10）螺旋化的支撑结构（26）共挤出的卷边元件（24）。支撑结构（26）包括不同类型的应变消除部分（30），其能够分别允许结构支撑的移植物（10）的纵向和径向膨胀。应变消除部分（30）还可以包括在结构上支撑的移植物在血管或体腔内膨胀时形成向外突出的倒钩（62）的未连接的端部。用于制造结构支撑的移植物的方法包括选择或制备具有应变消除部分的支撑结构，将结构支撑件用滚珠元件共挤出，用共挤出结构在管状移植物周围形成螺旋，挤压结构到管状移植物。

5. 发明授权

US07468071B2 Diametrically adaptable encapsulated stent and methods for deployment thereof 失效
标题翻译：直径适应性包封支架及其部署方法
公开(公告)号：US07468071B2
公开(公告)日：2008-12-23
申请号：US10873085
申请日：2004-06-21
申请人： Tarun J. Edwin , Brendan McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Brendan McCrea , Christopher E. Banas
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2002/072 , A61L27/507 , A61L31/048 , A61L31/10 , A61L2400/16 , B29C55/005 , B29C55/22 , B29K2027/18 , Y10S623/901 , C08L27/18
摘要： An implantable intraluminal device having a self-expanding stent encapsulated between a first and second seamless ePTFE tube. The implantable intraluminal device has a reduced first diametric dimension and an expanded second diametric dimension, and is adapted to be modeled to the in vivo profile of a receiving anatomical structure through radial expansion of at least a portion thereof to a third diametric dimension greater than the second diametric dimension.
摘要翻译：一种可植入管腔内装置，其具有封装在第一和第二无缝ePTFE管之间的自扩张支架。可植入管腔内装置具有减小的第一直径尺寸和扩大的第二直径尺寸，并且适于通过其至少一部分的径向膨胀至大于第二直径尺寸的第三直径尺寸而被建模为接收解剖结构的体内轮廓第二直径尺寸。

6. 发明授权

US07004966B2 Selective adherence of stent-graft coverings 有权
公开(公告)号：US07004966B2
公开(公告)日：2006-02-28
申请号：US10410589
申请日：2003-04-09
申请人： Tarun J. Edwin , Scott L. Randall , Brendan McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Scott L. Randall , Brendan McCrea , Christopher E. Banas
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/072 , A61F2002/075 , A61F2230/005 , A61F2230/0054 , A61F2240/001 , A61F2250/0003 , A61F2250/0014 , A61F2250/0039 , A61F2250/0067 , B29C65/02 , B29C65/48 , B29L2031/753
摘要： An endoluminal vascular device having a plurality of predetermined boding locations between respective first and second covering members to selectively encapsulate a support member. Selective bonding between the first and second covering members results in unbonded slip pockets to accommodate movement of the support member. Such a configuration allows compression of the support member with minimal force and also promotes a low profile of the compressed device. Unbonded regions of the covering members also encourage enhanced cellular penetration for rapid healing and can be configured to hold bioactive substances that diffuse through the covering members.

7. 发明授权

US06797217B2 Methods for making encapsulated stent-grafts 失效
标题翻译：包封支架移植物的制备方法
公开(公告)号：US06797217B2
公开(公告)日：2004-09-28
申请号：US10242160
申请日：2002-09-12
申请人： Brendan J. McCrea , Tarun J. Edwin , Christopher E. Banas
发明人： Brendan J. McCrea , Tarun J. Edwin , Christopher E. Banas
IPC分类号： B29C6102
CPC分类号： A61F2/82 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2002/072 , A61L27/507 , A61L31/048 , A61L31/10 , A61L2400/16 , B29C55/005 , B29C55/22 , B29K2027/18 , Y10S623/901 , C08L27/18
摘要： Shape memory alloy and elastically self-expanding endoluminal stents which are at least partially encapsulated in a substantially monolithic expanded polytetrafluorethylene (“ePTFE”) covering. An endoluminal stent, which has a reduced diametric dimension for endoluminal delivery and a larger in vivo final diametric diameter is encapsulated in an ePTFE covering which circumferentially covers both the luminal and abluminal walls along at least a portion of the longitudinal extent of the endoluminal stent. The endoluminal stent is fabricated from a shape memory alloy which exhibits either shape memory or pseudoelastic properties or from an elastic material having an inherent spring tension.
摘要翻译：形状记忆合金和弹性自膨胀腔内支架，其至少部分包封在基本上整齐的膨胀聚四氟乙烯（“ePTFE”）中。内窥镜支架具有减小的内腔输送的直径尺寸和较大的体内最终直径直径被封装在ePTFE覆盖物中，其沿着沿内腔支架的纵向范围的至少一部分圆周地覆盖管腔和囊腔壁。内镜支架由形状记忆合金制成，其形状记忆或假弹性性质或具有固有弹簧张力的弹性材料。

8. 发明授权

US06547814B2 Selective adherence of stent-graft coverings 有权
标题翻译：支架移植物覆盖物的选择性粘附
公开(公告)号：US06547814B2
公开(公告)日：2003-04-15
申请号：US09764811
申请日：2001-01-16
申请人： Tarun J. Edwin , Scott L. Randall , Brendan J. McCrea , Christopher E. Banas
发明人： Tarun J. Edwin , Scott L. Randall , Brendan J. McCrea , Christopher E. Banas
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/072 , A61F2002/075 , A61F2230/005 , A61F2230/0054 , A61F2240/001 , A61F2250/0003 , A61F2250/0014 , A61F2250/0039 , A61F2250/0067 , B29C65/02 , B29C65/48 , B29L2031/753
摘要： A method for selectively bonding layers of polymeric material, especially expanded polytetrafluoroethylene (ePTFE), to create endoluminal vascular devices. In a preferred method the selective bonding is achieved by applying pressure to selected areas using a textured mandrel. This permits a stent device to be encapsulated between two layers of ePTFE with unbonded slip pockets to accommodate movement of the structural members of the stent. This allows stent compression with minimal force and promotes a low profile of the compressed device. Unbonded regions of ePTFE allow enhanced cellular penetration for rapid healing and can also contain bioactive substance that will diffuse through the ePTFE to treat the vessel wall.
摘要翻译：选择性地粘合聚合物材料层，特别是膨胀聚四氟乙烯（ePTFE）的层以产生腔内血管装置的方法。在优选的方法中，通过使用纹理心轴向选定区域施加压力来实现选择性粘合。这允许将支架装置封装在具有未粘合的滑动袋的两层ePTFE之间以适应支架的结构构件的运动。这允许以最小的力量进行支架压缩并且促进压缩装置的低轮廓。 ePTFE的未结合区域允许增强细胞穿透以快速愈合，还可以含有生物活性物质，其将通过ePTFE扩散以治疗血管壁。

9. 发明授权

US5749880A Endoluminal encapsulated stent and methods of manufacture and endoluminal delivery 失效
公开(公告)号：US5749880A
公开(公告)日：1998-05-12
申请号：US508033
申请日：1995-07-27
申请人： Christopher E. Banas , Tarun J. Edwin
发明人： Christopher E. Banas , Tarun J. Edwin
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61F2/07 , A61F2/90 , A61F2002/072
摘要： An radially expandable stent-graft and method of making the same, including at least one a stent member encapsulated between at least two longitudinally expanded polytetrafluoroethylene (ePTFE) coverings. The at least one stent member has openings through wall surfaces of the stent to permit radial expansion. The at least two longitudinally expanded ePTFE coverings are circumferentially applied over the at least one stent member in their unsintered state, and sintered during application of a circumferential pressure to bond the ePTFE around and through the wall surfaces of the stent. The sintered ePTFE forms a substantially continuous, monolithic and integral encapsulation of the at least one stent. Upon radial expansion of the stent-graft, the stent and the ePTFE node-fibril microstructure radially deform. Radial deformation of the ePTFE encapsulation results in nodal elongation in the axis of radial expansion. After radial expansion of the stent-graft, a substantial bonded area remains intact and maintains the encapsulation of the stent in vivo.

10. 发明申请

US20120193018A1 Methods for Making a Supported Graft 失效
标题翻译：制作支持移植的方法
公开(公告)号：US20120193018A1
公开(公告)日：2012-08-02
申请号：US13434472
申请日：2012-03-29
申请人： Christopher E. Banas , Tarun J. Edwin , Brendan J. McCrea , Rajagopal R. Kowligi
发明人： Christopher E. Banas , Tarun J. Edwin , Brendan J. McCrea , Rajagopal R. Kowligi
IPC分类号： B32B37/14 , B32B38/00
CPC分类号： A61F2/88 , A61F2/0077 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/072 , A61F2002/075 , A61F2002/30093 , A61F2002/30448 , A61F2210/0019 , A61F2210/0076 , A61F2220/005 , A61L31/048 , C08L27/18
摘要： A method for forming a self-expanding stent-graft, including coupling a shape memory member to a polymer cladding to form a polymer clad member, disposing a length of the polymer clad member in an overlapping helical manner about a longitudinal axis, joining and sealing adjacent overlapping regions of the polymer clad member to form a stent-graft, manipulating the stent-graft from a first diameter to a second diameter smaller than the first diameter, and loading the stent-graft into a restraining sheath at the second diameter, the restraining sheath preventing expansion of the stent-graft from the second diameter to the first diameter.
摘要翻译：一种形成自扩张型支架移植物的方法，包括将形状记忆元件耦合到聚合物包层以形成聚合物包覆部件，将一段长度的聚合物包覆部件以围绕纵向轴线的重叠螺旋方式设置，接合和密封聚合物包覆部件的相邻重叠区域以形成支架移植物，将支架移植物从第一直径操纵至小于第一直径的第二直径，并将支架移植物装载到第二直径的约束护套中，限制护套防止支架移植物从第二直径扩展到第一直径。

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